Metformin Hcl combined with Pregabalin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Muscle Twitching Other Serious 10/1/2006 62 Male 179 lb 12/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Twitching Other Serious 10/1/2006 62 Male 179 lb 2/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Other Serious 1/1/2007 46 Male 243 lb 4/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Interaction Other Serious 59 Male 6/19/2007 Ireland
Primary
Concomitant
Interacting
Jaundice Hospitalization Male 6/28/2007 Physician France
Primary
Secondary
Concomitant
Unresponsive To Stimuli Disability 4/14/2007 68 Male 262 lb 7/30/2007 Pharmacist United States
Primary
Concomitant
Serotonin Syndrome Other Serious 1/1/2007 43 Male 9/27/2007 Physician United States
Primary
Concomitant
Serotonin Syndrome Other Serious 1/1/2007 43 Male 10/29/2007 Physician United States
Primary
Concomitant
Oesophageal Carcinoma Life Threatening 48 Male 12/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Productive Cough Other Serious 12/10/2007 Female 174 lb 2/8/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 50 Female 3/3/2008 United States
Primary
Concomitant
Interacting
Vomiting Hospitalization 6/8/2006 Female 3/7/2008 United States
Primary
Secondary
Concomitant
Death Death 3/15/2008 61 Female 3/21/2008 Netherlands
Primary
Secondary
Concomitant
Renal Impairment Other Serious 50 Female 3/21/2008 Physician United States
Primary
Concomitant
Interacting
White Blood Cell Count Increased Required Intervention 50 Female 3/19/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 3/15/2008 61 Female 3/28/2008 Physician Netherlands
Primary
Secondary
Concomitant
Renal Impairment Other Serious 47 Male 4/18/2008 Other Health Professional Canada
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 50 Female 4/23/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 47 Male 4/25/2008 Canada
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 50 Female 5/2/2008 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Injury Other Serious 50 Female 4/25/2008 United States
Primary
Secondary
Death Death 3/15/2008 61 Female 5/19/2008 Physician Netherlands
Primary
Secondary
Concomitant
Multiple Myeloma Life Threatening 5/1/2008 Female 187 lb 6/11/2008 Consumer Colombia
Primary
Concomitant
Rhabdomyolysis Other Serious 66 Male 7/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 47 Male 7/9/2008 Other Health Professional Canada
Primary
Concomitant
Interacting
Syncope Life Threatening 66 Male 7/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 66 Male 7/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sleep Disorder Other Serious 73 Male 8/5/2008 Netherlands
Primary
Secondary
Concomitant
Pruritus 6/19/2008 Female 218 lb 8/29/2008 United States
Primary
Concomitant
Alopecia 3/1/2008 Female 250 lb 9/2/2008 Consumer United States
Primary
Concomitant
Hepatic Haemorrhage Other Serious 6/1/2008 50 Male 8/26/2008 Physician Chile
Primary
Concomitant
Weight Loss Poor Female 182 lb 9/12/2008 Consumer United States
Primary
Concomitant
Photosensitivity Reaction Hospitalization 7/1/2007 Female 133 lb 9/12/2008 Physician United States
Primary
Concomitant
Renal Injury Hospitalization 50 Female 9/12/2008 United States
Primary
Concomitant
Vomiting 7/1/2008 Female 11/6/2008 Consumer United States
Primary
Concomitant
Cardiac Failure Other Serious 59 Male 11/21/2008 Italy
Primary
Concomitant
Paradoxical Drug Reaction Hospitalization Male 11/24/2008 Canada
Primary
Concomitant
Skin Burning Sensation 9/20/2008 Female 11/26/2008 United States
Primary
Concomitant
Blood Glucose Increased Male 11/26/2008 United States
Primary
Concomitant
Swelling Female 11/26/2008 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 11/3/2008 Male 12/8/2008 Physician France
Primary
Secondary
Concomitant
Arthralgia Hospitalization 4/14/2008 Male 228 lb 12/11/2008 United States
Primary
Secondary
Concomitant
Urticaria 5/1/2008 Female 162 lb 12/12/2008 United States
Primary
Concomitant
Interacting
Accidental Exposure 9/5/2008 Male 185 lb 12/12/2008 Consumer United States
Primary
Concomitant
Pain In Extremity 2/1/2008 Male 330 lb 12/12/2008 United States
Primary
Concomitant
Incorrect Dose Administered 10/31/2008 Female 210 lb 12/12/2008 Other Health Professional United States
Primary
Concomitant
Injection Site Reaction 6/1/2008 Female 12/12/2008 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 50 Female 12/11/2008 Physician United States
Primary
Concomitant
Myalgia Hospitalization 3/8/2009 Male 143 lb 3/12/2009 Physician India
Primary
Concomitant
Bronchospasm Other Serious 2/10/2009 58 Female 177 lb 3/13/2009 Physician United Kingdom
Primary
Concomitant
Myalgia Life Threatening 3/8/2009 Male 143 lb 3/16/2009 Physician India
Primary
Secondary
Concomitant
Myalgia Life Threatening 3/8/2009 Male 143 lb 3/16/2009 Physician India
Primary
Secondary
Concomitant
Myalgia Hospitalization 3/8/2009 Male 143 lb 3/20/2009 Physician India
Primary
Concomitant
Respiratory Tract Infection Hospitalization 3/8/2009 Male 143 lb 4/2/2009 Physician India
Primary
Concomitant
Wound Infection Other Serious 7/9/2004 35 Male 235 lb 4/10/2009 United States
Primary
Concomitant
Depression 7/8/2008 56 Male 252 lb 12/22/2008 Pharmacist United States
Primary
Concomitant
Nephropathy Other Serious 66 Male 4/23/2009 Physician United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Other Serious 50 Female 6/5/2009 Physician United States
Primary
Secondary
Concomitant
Normochromic Normocytic Anaemia Other Serious 66 Male 6/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 1/1/2009 75 Male 8/5/2009 Physician Switzerland
Primary
Secondary
Concomitant
Incorrect Dose Administered 9/5/2008 Male 185 lb 9/12/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 5/17/2009 54 Female 229 lb 9/10/2009 Consumer United States
Primary
Concomitant
Sensory Loss Other Serious 2/11/2009 Female 232 lb 9/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 9/23/2009 Male 255 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 6/7/2008 66 Male 11/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/7/2008 66 Male 11/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 1/1/2007 43 Male 11/30/2009 Physician United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 50 Female 12/7/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2007 Female 188 lb 12/22/2009 Physician United States
Primary
Concomitant
Drug Toxicity Death 56 Male 1/8/2010 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 56 Male 1/11/2010 Physician United States
Primary
Secondary
Poisoning Death 1/1/2008 56 Male 1/29/2010 Physician United States
Primary
Secondary
Poisoning Death 1/1/2008 56 Male 1/29/2010 Physician United States
Primary
Secondary
Poisoning Death 1/1/2008 56 Male 2/1/2010 Physician United States
Primary
Secondary
Completed Suicide Death 56 Male 2/24/2010 Physician United States
Primary
Secondary
Liver Function Test Abnormal 7/10/2009 52 Female 2/23/2010 Consumer United States
Primary
Secondary
Concomitant
Metabolic Acidosis Death 2/10/2010 65 Female 265 lb 3/11/2010 Physician Germany
Primary
Secondary
Concomitant
Metabolic Acidosis Death 2/10/2010 65 Female 265 lb 3/19/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Metabolic Acidosis Death 2/10/2010 65 Female 265 lb 3/22/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Metabolic Acidosis Death 2/10/2010 65 Female 265 lb 3/23/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Metabolic Acidosis Death 2/10/2010 65 Female 265 lb 3/23/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Metabolic Acidosis Death 2/10/2010 65 Female 265 lb 3/23/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Dyspnoea Other Serious 11/27/2007 62 Female 3/25/2010 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced 1/28/2010 80 Female 110 lb 3/30/2010 Spain
Primary
Concomitant
Somnolence Hospitalization 7/11/2001 79 Male 7/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/8/2010 79 Male 7/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 7/29/2010 United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 7/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 8/1/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/8/2010 79 Male 8/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 8/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/8/2010 79 Male 8/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/8/2010 79 Male 8/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/8/2010 79 Male 8/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Hospitalization 7/8/2010 79 Male 7/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 8/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 7/8/2010 79 Male 8/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 79 Male 8/7/2010 United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 8/19/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 8/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/8/2010 79 Male 8/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/8/2010 79 Male 8/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/8/2010 79 Male 8/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/8/2010 79 Male 8/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 9/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Hospitalization 7/8/2010 79 Male 9/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Hospitalization 79 Male 9/8/2010
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 10/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 10/8/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 10/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 10/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 2/7/2001 79 Male 10/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 9/19/2010 10/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 7/8/2010 79 Male 10/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 79 Male 10/12/2010 Other Health Professional
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/8/2010 79 Male 10/20/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 10/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 7/1/2010 79 Male 10/28/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 7/8/2010 79 Male 10/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 79 Male 11/5/2010 Other Health Professional
Primary
Secondary
Concomitant
Escherichia Urinary Tract Infection Hospitalization 10/17/2010 78 Female 148 lb 11/24/2010 Consumer United Kingdom
Primary
Concomitant
Drug Interaction Death 1/25/2011 Consumer Japan
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Hospitalization 11/10/2010 70 Male 2/7/2011 Pharmacist Spain
Primary
Concomitant
Febrile Neutropenia Hospitalization 3/30/2011 67 Male 4/20/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/30/2011 67 Male 4/28/2011 Physician Italy
Primary
Secondary
Concomitant
Nervousness Hospitalization 1/7/2011 84 Male 173 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 1/1/2010 67 Female 5/16/2011 Consumer United States
Primary
Concomitant
Dehydration Hospitalization 9/11/2009 52 Female 198 lb 5/25/2011 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 1/7/2011 84 Male 173 lb 5/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bradycardia Hospitalization 1/7/2011 84 Male 173 lb 6/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Completed Suicide Other Serious 1/1/2008 56 Male 7/20/2011 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2008 56 Male 7/21/2011 Physician United States
Primary
Secondary
Loss Of Consciousness Life Threatening 7/14/2011 69 Male 174 lb 8/9/2011 Pharmacist United Kingdom
Primary
Concomitant
Pupillary Reflex Impaired Hospitalization 7/14/2011 69 Male 177 lb 8/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
Lymphadenopathy Other Serious 7/1/2007 71 Female 8/31/2011 United States
Primary
Concomitant
Bradycardia Hospitalization 1/7/2011 84 Male 173 lb 9/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Required Intervention 5/1/2011 83 Male 9/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Body Mass Index Decreased Hospitalization 54 Male 10/6/2011 Physician United Kingdom
Primary
Concomitant
Hypophagia Hospitalization 54 Male 10/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Nausea Other Serious 54 Male 10/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Malaise Other Serious 54 Male 10/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Acute Sinusitis Hospitalization 10/10/2011 58 Female 203 lb 10/21/2011 Physician United States
Primary
Concomitant
Malaise Hospitalization 54 Male 10/21/2011 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Disorder Other Serious 54 Male 10/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Renal Failure Acute Other Serious 54 Male 10/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Gastrointestinal Disorder Other Serious 54 Male 10/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Renal Failure Acute Other Serious 54 Male 10/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Malaise Other Serious 54 Male 10/24/2011 Other Health Professional United Kingdom
Primary
Secondary

Drug Data