Metformin Hcl combined with Pravastatin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Nephrolithiasis Other Serious 7/1/2006 52 Female 1/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 75 Female 170 lb 2/8/2007 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/20/2006 Male 231 lb 4/4/2007 Pharmacist France
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/20/2006 Male 231 lb 4/19/2007 Pharmacist France
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Hospitalization 5/3/2007 62 Male 6/21/2007 Other Health Professional Germany
Primary
Secondary
Headache 3/1/2007 39 Female 300 lb 11/16/2007 Other Health Professional United States
Primary
Concomitant
Nausea 9/1/2006 56 Female 249 lb 12/19/2007 Consumer United States
Primary
Secondary
Concomitant
Coronary Artery Occlusion Hospitalization 1/8/2007 60 Female 160 lb 11/29/2007 Consumer United States
Primary
Concomitant
Lactic Acidosis Hospitalization 12/26/2007 68 Male 2/25/2008 France
Primary
Secondary
Arthralgia Hospitalization 1/22/2008 59 Male 4/18/2008 Other Health Professional France
Primary
Secondary
Hiccups Hospitalization 2/28/2008 Male 164 lb 4/30/2008 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 2/29/2008 75 Male 5/12/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 60 Male 5/10/2008 Pharmacist United States
Primary
Concomitant
Pruritus 1/1/2008 73 Female 8/15/2008 United States
Primary
Concomitant
Nausea 3/22/2008 62 Female 8/15/2008 United States
Primary
Concomitant
Screaming 6/26/2008 63 Female 8/15/2008 Physician United States
Primary
Concomitant
Haematoma Other Serious 8/3/2008 Male 8/29/2008 Pharmacist Switzerland
Primary
Concomitant
Cardiac Arrest Other Serious 8/16/2008 64 Male 9/5/2008 Ireland
Primary
Concomitant
Hepatitis Other Serious 51 Male 201 lb 9/22/2008 Consumer United Kingdom
Primary
Concomitant
Cardiac Arrest Death 8/16/2008 64 Male 10/1/2008 Ireland
Primary
Concomitant
Acute Myocardial Infarction Death 3/8/2008 Male 165 lb 10/14/2008 Other Health Professional Japan
Primary
Concomitant
Pruritus 1/1/2008 73 Female 11/14/2008 United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 2/29/2008 75 Male 12/3/2008 Other Health Professional France
Primary
Secondary
Concomitant
Rash Other Serious 7/1/2006 52 Female 99 lb 12/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Death 69 Female 1/21/2009 Other Health Professional United States
Primary
Secondary
Renal Injury 62 Male 2/18/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 7/31/2007 64 Male 3/18/2009 Korea, Republic Of
Primary
Secondary
Concomitant
Metastatic Neoplasm Other Serious Female 3/30/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Bacterial Female 269 lb 4/13/2009 United States
Primary
Concomitant
Vomiting Life Threatening 7/17/2004 Female 6/25/2009 Consumer Mexico
Primary
Secondary
Concomitant
Weight Decreased Other Serious 47 Male 7/9/2009 Consumer United States
Primary
Secondary
Concomitant
Peritoneal Fibrosis Other Serious 1/4/2009 51 Male 106 lb 8/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Peritoneal Fibrosis Other Serious 1/4/2009 51 Male 106 lb 8/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rash 3/1/2008 60 Female 165 lb 8/14/2009 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Hospitalization 88 Female 9/11/2009 United States
Primary
Concomitant
Orthostatic Hypotension 1/1/2008 46 Male 276 lb 10/6/2009 Pharmacist United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 9/23/2009 74 Male 11/5/2009 Physician United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 9/23/2009 74 Male 11/9/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/27/2009 66 Female 134 lb 12/22/2009 Consumer United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 9/23/2009 74 Male 12/31/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/27/2009 66 Female 1/7/2010 Physician United States
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Life Threatening 80 Male 3/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Life Threatening 80 Male 4/5/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Life Threatening 80 Male 4/10/2010 United Kingdom
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 3/2/2010 47 Female 4/20/2010 Other Health Professional France
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 4/1/2010 77 Male 6/29/2010 Physician France
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 4/1/2010 77 Male 6/28/2010 Physician France
Primary
Secondary
Concomitant
Drug Ineffective 12/1/2007 54 Male 220 lb 6/29/2010 Consumer United States
Primary
Concomitant
Wound Infection Other Serious 11/26/2009 59 Female 178 lb 7/6/2010 Physician Canada
Primary
Secondary
Concomitant
Wound Infection Other Serious 11/26/2009 59 Female 178 lb 7/8/2010 Physician Canada
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 1/1/2010 67 Female 294 lb 7/13/2010 Physician United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 84 Female 10/7/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 6/24/2010 65 Male 262 lb 10/18/2010 Physician United Kingdom
Primary
Concomitant
Off Label Use Other Serious 6/24/2010 65 Male 262 lb 10/18/2010 Physician United Kingdom
Primary
Concomitant
Interacting
Hypoglycaemia Other Serious 65 Male 10/15/2010 United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Abnormal 9/8/2010 75 Male 11/23/2010 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 63 Female 11/23/2010 Physician United States
Primary
Concomitant
Tendonitis Other Serious 70 Male 12/1/2010 Other Health Professional Netherlands
Primary
Concomitant
Pulmonary Embolism Hospitalization 12/6/2010 68 Male 179 lb 12/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 7/13/2010 52 Male 298 lb 12/20/2010 Physician United States
Primary
Concomitant
Death Death 9/8/2010 75 Male 12/21/2010 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 8/22/2010 67 Female 154 lb 12/16/2010 Physician United States
Primary
Concomitant
Insomnia 67 Male 2/24/2011 Consumer United States
Primary
Secondary
Concomitant
Lactic Acidosis Hospitalization 11/8/2010 81 Female 3/3/2011 Physician Germany
Primary
Concomitant
Lactic Acidosis Hospitalization 11/8/2010 81 Female 3/4/2011 Consumer Germany
Primary
Concomitant
Dyspepsia Hospitalization 1/1/2011 71 Male 192 lb 3/15/2011 Consumer United States
Primary
Concomitant
Pain Hospitalization 1/1/2011 71 Male 192 lb 3/29/2011 Physician United States
Primary
Concomitant
Chest Discomfort Hospitalization 1/11/2011 76 Male 4/1/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/11/2011 76 Male 4/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dermatitis Other Serious 9/23/2009 74 Male 4/11/2011 Physician United States
Primary
Secondary
Concomitant
Morphoea Other Serious 61 Female 4/20/2011 Physician United States
Primary
Concomitant
Electrocardiogram T Wave Peaked Life Threatening 12/24/2010 74 Female 5/20/2011 Consumer France
Primary
Secondary
Concomitant
Drug Ineffective Death 8/27/2010 74 Male 190 lb 5/24/2011 Physician France
Primary
Secondary
Concomitant
Drug Ineffective Death 8/27/2010 74 Male 190 lb 5/27/2011 Physician France
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 3/29/2011 77 Female 5/31/2011 Pharmacist Japan
Primary
Concomitant
Breast Cancer Hospitalization 7/25/2006 79 Female 137 lb 6/4/2011 Physician Japan
Primary
Concomitant
Malignant Neoplasm Of Ampulla Of Vater Other Serious 8/27/2010 74 Male 190 lb 6/10/2011 Physician France
Primary
Secondary
Concomitant
Dyskinesia Hospitalization 3/14/2011 53 Male 231 lb 6/16/2011 Other Health Professional France
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 10/13/2009 67 Female 152 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Hospitalization 5/26/2011 83 Female 7/8/2011 Other Health Professional France
Primary
Concomitant
Blood Amylase Increased Hospitalization 6/3/2011 50 Male 7/8/2011 Consumer United Kingdom
Primary
Concomitant
Duodenal Ulcer Hospitalization 82 Male 172 lb 7/7/2011 Pharmacist Canada
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 6/1/2011 72 Female 7/19/2011 Other Health Professional France
Primary
Concomitant
Hypoglycaemia Life Threatening 7/2/2011 91 Female 130 lb 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Other Serious 6/15/2011 73 Female 168 lb 8/5/2011 Consumer United States
Primary
Concomitant
Blood Glucose Increased 2/1/2011 52 Female 159 lb 8/6/2011 Consumer United States
Primary
Concomitant
Sinus Disorder 4/1/2011 52 Female 158 lb 8/6/2011 Consumer United States
Primary
Concomitant
Confusional State Other Serious 6/16/2011 73 Male 8/10/2011 Consumer France
Primary
Concomitant
Duodenal Ulcer Hospitalization 3/10/2011 82 Male 172 lb 8/25/2011 Other Health Professional Canada
Primary
Concomitant
Interacting
Gastritis Hospitalization 3/10/2011 82 Male 172 lb 8/15/2011 Other Health Professional Canada
Primary
Concomitant
Interacting
Balance Disorder Other Serious 6/16/2011 73 Male 176 lb 8/29/2011 Other Health Professional France
Primary
Concomitant
Pyrexia Hospitalization 1/26/2010 57 Female 9/7/2011 Consumer United States
Primary
Concomitant
Bradycardia Hospitalization 6/27/2011 67 Male 245 lb 9/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 6/15/2011 73 Female 168 lb 9/8/2011 United States
Primary
Concomitant
Retinal Haemorrhage Other Serious 7/24/2011 75 Female 132 lb 9/8/2011 Physician Japan
Primary
Concomitant
Pustular Psoriasis Hospitalization 6/1/2011 64 Female 9/13/2011 Consumer Germany
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 9/1/2011 86 Female 114 lb 9/14/2011 Physician United States
Primary
Concomitant
Hypoglycaemic Encephalopathy Hospitalization Female 9/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Pressure Increased 62 Female 161 lb 9/27/2011 Consumer United States
Primary
Secondary
Concomitant
Hypoglycaemic Encephalopathy Hospitalization Female 9/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypoglycaemic Encephalopathy Hospitalization Female 10/5/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Retinal Haemorrhage Other Serious 7/24/2011 75 Female 132 lb 10/6/2011 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 7/25/2011 73 Female 10/17/2011 Physician United States
Primary
Concomitant
Ectopic Pregnancy Other Serious 1/1/2008 26 Female 168 lb 10/21/2011 Lawyer United States
Primary
Concomitant
Acute Myocardial Infarction Death 9/6/2011 86 Female 114 lb 10/28/2011 Physician United States
Primary
Concomitant
Depressive Symptom Hospitalization 7/8/2011 79 Female 119 lb 11/1/2011 Consumer Japan
Primary
Concomitant
Neuropathy Peripheral Disability 3/1/2011 63 Male 170 lb 11/3/2011 Consumer Netherlands
Primary
Secondary
Concomitant
Visual Impairment Other Serious 60 Male 11/4/2011 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2011 68 Male 190 lb 11/18/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 6/3/2011 61 Female 99 lb 11/18/2011 Physician Japan
Primary
Concomitant
Pancreatitis Hospitalization 9/1/2011 54 Female 11/22/2011 Consumer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 77 Female 11/23/2011 Physician Japan
Primary
Concomitant
Death Death 11/7/2011 74 Male 11/28/2011 Pharmacist United States
Primary
Concomitant
Diarrhoea Disability 7/25/2011 73 Female 11/30/2011 Physician United States
Primary
Concomitant
Renal Disorder Other Serious 6/26/2009 73 Male 255 lb 12/1/2011 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 9/1/2011 54 Female 12/5/2011 Other Health Professional United States
Primary
Concomitant
Dizziness Hospitalization 10/22/2011 55 Female 357 lb 12/6/2011 Consumer United States
Primary
Concomitant
Abdominal Discomfort Other Serious 6/15/2011 73 Female 168 lb 12/13/2011 Physician United States
Primary
Concomitant
Pain Other Serious 1/1/2008 26 Female 168 lb 12/15/2011 Consumer United States
Primary
Concomitant
Muscle Disorder Other Serious 12/1/2010 73 Male 161 lb 12/22/2011 Consumer United States
Primary
Secondary
Concomitant
Metastases To Central Nervous System Death Male 12/22/2011 Physician United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 1/1/2009 46 Male 172 lb 12/23/2011 Consumer United States
Primary
Secondary
Concomitant
Hospitalisation Hospitalization Female 73 lb 12/28/2011 Physician Japan
Primary
Concomitant
Pancreatitis Acute Hospitalization 11/25/2011 1/2/2012 Physician Japan
Primary
Concomitant
Depression Other Serious 55 Female 1/5/2012 Consumer United States
Primary
Concomitant
Hyperhidrosis Other Serious 6/15/2011 73 Female 168 lb 1/17/2012 Consumer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 62 Female 1/19/2012 United States
Primary
Concomitant
Abnormal Sensation In Eye Hospitalization 1/1/2011 73 Male 146 lb 1/20/2012 Physician Japan
Primary
Concomitant
Pancreatitis Acute Hospitalization 11/25/2011 40 Male 207 lb 1/23/2012 Physician Japan
Primary
Concomitant
Pregnancy On Oral Contraceptive Other Serious 1/1/2008 26 Female 168 lb 1/24/2012 Other Health Professional United States
Primary
Concomitant
Hyponatraemia Hospitalization 10/31/2011 78 Female 1/27/2012 Consumer France
Primary
Concomitant
Folliculitis 11/30/2011 53 Female 230 lb 1/29/2012 Consumer United States
Primary
Concomitant
Nausea Female 230 lb 1/29/2012 Consumer United States
Primary
Concomitant
Muscle Spasms 3/1/2011 55 Female 237 lb 1/28/2012 Consumer United States
Primary
Concomitant
Hepatic Cirrhosis Other Serious 1/28/2011 76 Female 1/31/2012 Physician France
Primary
Secondary
Diabetes Mellitus Other Serious 67 Female 150 lb 2/1/2012 Consumer United States
Primary
Concomitant
Abdominal Discomfort Other Serious 6/15/2011 73 Female 168 lb 2/6/2012 Consumer United States
Primary
Concomitant
Low Density Lipoprotein Increased Other Serious 1/1/2011 73 Female 146 lb 2/16/2012 Consumer United States
Primary
Secondary
Concomitant
Decreased Activity Hospitalization Female 73 lb 2/17/2012 Physician Japan
Primary
Concomitant
Electrocardiogram St Segment Depression Other Serious 4/18/2011 70 Female 2/13/2012 Japan
Primary
Concomitant
Blood Glucose Increased Other Serious 1/1/2010 68 Female 2/24/2012 Consumer United States
Primary
Secondary
Concomitant
Abdominal Discomfort 58 Female 2/24/2012 Consumer United States
Primary
Concomitant
Diarrhoea 71 Female 2/24/2012 Consumer United States
Primary
Concomitant
Neuropathy Peripheral 2/24/2012 Pharmacist United States
Primary
Secondary
Drug Ineffective Hospitalization 1/27/2012 63 Male 176 lb 2/27/2012 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/18/2012 82 Female 2/27/2012 Consumer Germany
Primary
Secondary
Concomitant
Malignant Neoplasm Of Ampulla Of Vater Other Serious 8/19/2010 74 Male 190 lb 3/2/2012 Physician France
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Other Serious 11/18/2011 42 Male 3/12/2012 Physician Japan
Primary
Concomitant
Neoplasm Progression Other Serious 11/7/2011 82 Male 149 lb 3/14/2012 Physician Japan
Primary
Concomitant
Hypertension 65 Male 214 lb 3/14/2012 Physician United States
Primary
Concomitant

Drug Data