Metformin Hcl combined with Pioglitazone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Middle Insomnia 8/1/2006 54 Female 152 lb 10/11/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 12/26/2006 71 Female 150 lb 1/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Uveitis Other Serious 33 Female 1/24/2007 United Kingdom
Primary
Secondary
Paraesthesia Other Serious 1/7/2007 67 Female 1/31/2007 Pharmacist United Kingdom
Primary
Concomitant
High Density Lipoprotein Decreased Other Serious 59 Male 1/31/2007 United Kingdom
Primary
Secondary
Concomitant
High Density Lipoprotein Decreased Other Serious 54 Male 1/31/2007 United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 7/1/2000 Female 2/6/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 12/26/2006 71 Female 150 lb 2/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 12/28/2006 71 Female 150 lb 2/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophageal Adenocarcinoma Other Serious 10/1/2006 65 Male 220 lb 2/14/2007 Physician United States
Primary
Concomitant
Malaise Disability 5/10/2006 66 Female 243 lb 3/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Heart Rate Irregular 10/1/2006 60 Female 184 lb 1/12/2007 Consumer United States
Primary
Concomitant
Personality Change Other Serious 3/1/2007 Female 180 lb 4/9/2007 Consumer United States
Primary
Secondary
Concomitant
Malaise Disability 5/10/2006 66 Female 243 lb 4/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Liver Injury Hospitalization 73 Female 73 lb 4/12/2007 Physician Belgium
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 3/27/2007 74 4/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Personality Change Other Serious 3/1/2007 Female 197 lb 5/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Life Threatening 1/12/2007 Male 150 lb 5/11/2007 Physician France
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/12/2007 57 Male 401 lb 4/30/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 53 Male 216 lb 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 11/18/2006 56 Female 4/26/2007 Consumer United States
Primary
Concomitant
Hyperglycaemia Other Serious 12/1/2005 48 Female 207 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Pleuropericarditis Hospitalization 6/18/2006 Male 198 lb 6/29/2007 Physician Canada
Primary
Concomitant
Headache 6/1/2007 8 Male 200 lb 7/10/2007 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 60 Male 8/22/2007 Physician United Kingdom
Primary
Concomitant
Joint Dislocation Hospitalization 7/23/2007 53 Female 9/12/2007 Other Health Professional United States
Primary
Concomitant
Joint Dislocation Hospitalization 7/23/2007 53 Female 9/17/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 60 Male 9/25/2007 Physician United Kingdom
Primary
Concomitant
Palpitations Other Serious 68 Male 9/27/2007 United Kingdom
Primary
Concomitant
Anaphylactic Shock Other Serious Female 10/26/2007 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 10/24/2007 40 Male 11/8/2007 Physician United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 3/1/2007 59 Male 11/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 6/1/2005 59 Male 11/12/2007 Other Health Professional Germany
Primary
Concomitant
Medication Error Death 9/5/2006 78 Female 201 lb 11/21/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Wrong Drug Administered Other Serious 1/1/2006 70 Female 168 lb 10/22/2007 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 9/24/2007 Female 12/3/2007 Consumer Germany
Primary
Concomitant
Renal Tubular Disorder Other Serious 70 Male 12/14/2007 Japan
Primary
Secondary
Concomitant
Joint Swelling Other Serious 1/1/2007 46 Male 12/14/2007 Pharmacist Germany
Primary
Concomitant
Interacting
Herpes Zoster 9/21/2007 Female 158 lb 12/14/2007 United States
Primary
Concomitant
Injection Site Pain Female 220 lb 12/14/2007 Consumer United States
Primary
Concomitant
Paraesthesia 10/24/2007 Male 241 lb 12/14/2007 Consumer United States
Primary
Concomitant
Anaphylactic Shock Other Serious Female 12/11/2007 United States
Primary
Concomitant
Renal Tubular Disorder Other Serious 70 Male 12/18/2007 Japan
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 12/21/2007 Physician United Kingdom
Primary
Concomitant
Nocturia Other Serious 1/1/2007 Male 165 lb 12/21/2007 Physician United States
Primary
Secondary
Concomitant
Myositis Life Threatening 11/14/2007 46 Male 12/28/2007
Primary
Secondary
Concomitant
Trichophytosis Other Serious 64 Female 1/31/2008
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 1/1/2007 Female 2/1/2008 Other Health Professional France
Primary
Concomitant
Interacting
Herpes Simplex Other Serious 1/1/2007 40 Male 2/7/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2007 Female 2/15/2008 Other Health Professional France
Primary
Concomitant
Interacting
Pulmonary Embolism Hospitalization 1/23/2008 47 Female 256 lb 2/19/2008 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/23/2008 47 Female 256 lb 2/22/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2007 Female 2/28/2008 Other Health Professional France
Primary
Concomitant
Interacting
Pancreatitis Acute Hospitalization 12/16/2007 60 Female 123 lb 3/5/2008 Physician India
Primary
Concomitant
Hypertension Other Serious 60 Male 3/26/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Other Serious 60 Male 4/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 3/19/2008 Male 201 lb 4/11/2008 Consumer United Kingdom
Primary
Concomitant
Hypertension Other Serious 60 Male 4/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 195 lb 4/16/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/1/2008 Female 4/17/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 77 Female 4/22/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 2/14/2008 Male 220 lb 4/25/2008 Physician Switzerland
Primary
Concomitant
Pitting Oedema Other Serious 4/17/2008 71 Male 220 lb 5/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Withdrawal Syndrome Other Serious 9/16/1997 37 Female 5/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Male 195 lb 5/8/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/7/2008 42 Female 4/28/2008 Pharmacist United States
Primary
Concomitant
Muscle Spasms 4/3/2008 Female 280 lb 6/12/2008 United States
Primary
Concomitant
Sensory Disturbance Other Serious 6/6/2008 Female 6/25/2008 Other Health Professional Canada
Primary
Concomitant
Hypoglycaemia Other Serious 2/1/2008 65 Male 327 lb 4/30/2008 United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 7/20/2007 52 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Pregnancy Other Serious 12/1/2007 Female 166 lb 6/20/2008 Physician United States
Primary
Secondary
Abortion Spontaneous Other Serious 5/30/2004 46 Female 233 lb 7/11/2008 Pharmacist United States
Primary
Concomitant
Fatigue Hospitalization 2/14/2008 Male 220 lb 7/29/2008 Physician Switzerland
Primary
Concomitant
Flushing 7/1/2007 Female 8/27/2008 Pharmacist United States
Primary
Concomitant
Pruritus 1/1/2006 Male 168 lb 8/27/2008 Physician United States
Primary
Concomitant
Vomiting 3/1/2008 Male 180 lb 8/27/2008 Consumer United States
Primary
Concomitant
Flatulence 6/21/2008 Female 225 lb 8/27/2008 United States
Primary
Concomitant
Pollakiuria 11/1/2007 Female 241 lb 8/27/2008 Consumer United States
Primary
Concomitant
Anxiety 5/1/2008 50 Male 8/29/2008
Primary
Concomitant
Skin Burning Sensation 6/17/2008 Male 8/29/2008 United States
Primary
Concomitant
Gingival Pain 7/13/2008 55 Male 8/29/2008 United States
Primary
Concomitant
Diarrhoea 7/9/2008 59 Male 8/29/2008 United States
Primary
Concomitant
Muscular Weakness 7/16/2008 Male 250 lb 8/29/2008 United States
Primary
Concomitant
Medication Residue 1/1/2007 Male 150 lb 9/2/2008 Physician United States
Primary
Concomitant
Drug Level Decreased Female 170 lb 9/2/2008 Other Health Professional United States
Primary
Concomitant
Blister 5/12/2008 Female 188 lb 9/12/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 219 lb 9/12/2008 United States
Primary
Concomitant
Tuberculin Test Positive 7/11/2008 Female 200 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Injection Site Pain 1/1/2004 Female 211 lb 9/12/2008 Consumer United States
Primary
Concomitant
Contusion 5/1/2008 Female 170 lb 9/12/2008 Consumer United States
Primary
Concomitant
Respiratory Tract Congestion 8/5/2008 Female 200 lb 9/12/2008 United States
Primary
Concomitant
Syncope Hospitalization 6/1/2008 137 lb 9/12/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 5/1/2008 69 Male 9/14/2008 Physician Switzerland
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 8/4/2008 59 Male 9/17/2008 Physician France
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 7/1/2008 Female 326 lb 9/25/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 Female 161 lb 9/29/2008 United States
Primary
Concomitant
Thyroid Cancer Other Serious 11/1/2006 Male 272 lb 9/22/2008 Consumer United States
Primary
Concomitant
Tachycardia Other Serious 8/27/2008 Male 198 lb 10/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/4/2008 80 Female 110 lb 10/6/2008 Pharmacist United States
Primary
Concomitant
High Density Lipoprotein Decreased Other Serious 66 Female 10/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 9/30/2008 Male 269 lb 11/13/2008 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/15/2008 64 Male 166 lb 7/17/2008 Pharmacist United States
Primary
Concomitant
Thyroid Cancer Other Serious 8/23/2006 Male 272 lb 11/21/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 9/26/2008 58 Female 207 lb 11/26/2008 Physician Brazil
Primary
Secondary
Concomitant
Muscular Weakness 7/16/2008 Male 250 lb 11/26/2008 United States
Primary
Concomitant
Blood Glucose Increased 9/8/2008 Male 11/26/2008 United States
Primary
Concomitant
Burning Sensation 9/26/2008 Male 11/26/2008 United States
Primary
Concomitant
Rash 10/1/2008 Male 11/26/2008 Physician
Primary
Concomitant
Cellulitis Hospitalization 10/31/2008 Female 269 lb 12/2/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/24/2008 Male 322 lb 12/3/2008 Consumer United Kingdom
Primary
Concomitant
Tenderness 3/15/2008 Male 235 lb 12/4/2008 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 1/1/2007 Female 200 lb 12/4/2008 Consumer United States
Primary
Concomitant
Treatment Noncompliance Life Threatening 10/14/2008 43 Female 12/3/2008 Other Health Professional United States
Primary
Concomitant
Procedural Complication 6/1/2008 Female 230 lb 12/12/2008 Consumer United States
Primary
Concomitant
Hyperhidrosis 6/1/2008 Female 156 lb 12/12/2008 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 11/12/2008 Female 192 lb 12/12/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2007 Female 12/16/2008 Other Health Professional France
Primary
Concomitant
Interacting
Ascites Other Serious 11/1/2008 70 Male 12/17/2008 Pharmacist Korea, Republic Of
Primary
Concomitant
Completed Suicide Death 1/1/2007 44 Male 12/22/2008 Physician United States
Primary
Secondary
Urinary Tract Infection Other Serious 9/26/2008 58 Female 207 lb 12/24/2008 Physician Brazil
Primary
Secondary
Concomitant
Completed Suicide Death 44 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Urinary Tract Infection Other Serious 9/26/2008 58 Female 207 lb 12/31/2008 Physician Brazil
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 2/14/2008 Male 220 lb 1/14/2009 Physician Switzerland
Primary
Concomitant
Poisoning Death 44 Male 1/15/2009 Physician United States
Primary
Secondary
Completed Suicide Death 1/29/2009 Other Health Professional United States
Primary
Secondary
Fatigue Hospitalization 11/1/2008 75 Male 2/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Polymyalgia Rheumatica Other Serious 7/29/2006 Female 166 lb 2/27/2009 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 6/30/2008 Male 280 lb 2/27/2009 Physician United States
Primary
Concomitant
Intentional Overdose Hospitalization 1/1/2009 29 Male 3/17/2009 Other Health Professional Canada
Primary
Secondary
Polymyalgia Rheumatica Other Serious 7/29/2006 Female 166 lb 3/16/2009 Physician United States
Primary
Concomitant
Myalgia Other Serious 1/1/2006 56 Male 4/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization Male 4/16/2009 Physician United Kingdom
Primary
Concomitant
Gastroenteritis Other Serious 69 Male 4/23/2009 Greece
Primary
Concomitant
Lethargy Required Intervention 2/18/2009 79 Male 217 lb 2/18/2009 Pharmacist United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 1/1/2009 Female 288 lb 4/29/2009 Consumer United States
Primary
Concomitant
Palpitations Other Serious 1/30/2009 61 Female 93 lb 5/11/2009 Other Health Professional Thailand
Primary
Secondary
Concomitant
Pancreatitis Other Serious 6/30/2008 Male 280 lb 5/12/2009 Physician United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 1/1/2008 Male 280 lb 5/18/2009 Physician United States
Primary
Concomitant
Glycosylated Haemoglobin Increased Other Serious Female 6/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Swollen Tongue Other Serious 3/25/2009 54 Female 260 lb 6/16/2009 Physician United Kingdom
Primary
Concomitant
Glycosylated Haemoglobin Increased Other Serious Female 6/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Oedema Peripheral 6/14/2008 Female 185 lb 6/30/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/6/2002 32 Male 154 lb 7/10/2009 United States
Primary
Concomitant
Pancreatitis Acute Life Threatening Male 266 lb Physician United States
Primary
Secondary
Concomitant
Left Ventricular Failure Other Serious 4/9/2009 76 Male 8/20/2009 United Kingdom
Primary
Concomitant
Weight Increased 1/1/2006 Female 211 lb 8/25/2009 Consumer United States
Primary
Concomitant
Thyroid Cancer Other Serious 8/23/2006 Male 272 lb 9/3/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 8/1/2009 Male 222 lb 9/3/2009 Consumer United States
Primary
Concomitant
Skin Ulcer 1/1/2005 Female 269 lb 9/11/2009 Physician United States
Primary
Concomitant
Incorrect Dose Administered 5/26/2007 Female 125 lb 9/11/2009 Consumer United States
Primary
Concomitant

Drug Data