Metformin Hcl combined with Paroxetine Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatic Enzyme Abnormal Required Intervention 7/29/2005 67 Male 188 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Diarrhoea Other Serious 10/19/2005 Male 209 lb 12/14/2005 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 10/1/2005 51 Male 2/23/2006 Consumer United States
Primary
Secondary
Concomitant
Cholestasis Hospitalization 7/1/2005 75 Female 8/30/2006 Other Health Professional Japan
Primary
Concomitant
Sudden Death Death 8/7/2006 62 Male 10/9/2006 Physician United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 1/1/2006 53 Female 150 lb 1/15/2007 Consumer United States
Primary
Concomitant
Hepatitis Life Threatening 12/13/2004 Female 1/16/2007 Canada
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/12/2006 46 Male 1/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urticaria 11/7/2005 41 Female 12/26/2006 Pharmacist United States
Primary
Concomitant
Tension 4/15/2006 84 Male 2/6/2007 Consumer United States
Primary
Secondary
Concomitant
Overdose Death 1/25/2007 60 Male 2/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Overdose Death 1/25/2007 60 Male 213 lb 2/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 1/1/2005 52 Female 150 lb 3/1/2007 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 1/1/2005 52 Female 150 lb 3/7/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 12/12/2006 46 Male 3/23/2007 Physician United Kingdom
Primary
Concomitant
Tremor Disability 1/1/2005 77 Female 192 lb 11/8/2007 Consumer France
Primary
Concomitant
Toe Amputation Other Serious 2/1/2007 82 Male 178 lb 11/12/2007 Consumer United States
Primary
Concomitant
Pulmonary Embolism Death 9/15/2007 Female 11/13/2007 United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 5/1/2007 55 Female 11/20/2007 France
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/15/2007 Female 11/22/2007 United Kingdom
Primary
Secondary
Concomitant
Tremor Disability 1/1/2005 77 Female 192 lb 12/21/2007 Consumer France
Primary
Concomitant
Renal Failure Acute Life Threatening 10/1/2007 61 Female 2/12/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Tachycardia Other Serious 1/24/2008 Female 2/14/2008 Pharmacist United States
Primary
Concomitant
Visual Disturbance Disability 10/1/2007 57 Female 315 lb 3/3/2008 Consumer United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 65 Female 254 lb 3/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 65 Female 3/13/2008 United Kingdom
Primary
Secondary
Concomitant
Lung Neoplasm Hospitalization 3/1/2008 Female 145 lb 4/4/2008 Physician United States
Primary
Concomitant
Blood Glucose Decreased Other Serious 2/1/2007 Male 237 lb 4/11/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 69 Male 181 lb 4/11/2008 Physician United States
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 4/29/2007 75 Male 4/14/2008 Physician Germany
Primary
Secondary
Concomitant
Interacting
Weight Decreased Other Serious 69 Male 181 lb 4/18/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2007 Female 233 lb 4/24/2008 Physician United States
Primary
Concomitant
Melaena Hospitalization 11/25/2007 57 Female 220 lb 5/1/2008 Physician Australia
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 9/16/1997 37 Female 5/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Overdose Death 1/25/2007 60 Male 213 lb 5/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Congenital Anomaly 12/27/2006 Female 5/30/2008 Lawyer United States
Primary
Secondary
Concomitant
Vasculitis Other Serious 5/16/2008 Female 6/5/2008 Physician Sweden
Primary
Concomitant
Vasculitis Other Serious 5/16/2008 Female 6/9/2008 Physician Sweden
Primary
Concomitant
Renal Failure Acute Other Serious 75 Female 6/12/2008 Other Health Professional Germany
Primary
Concomitant
Pancreatitis Acute Hospitalization 8/14/2007 Female 215 lb 4/10/2008 Pharmacist United States
Primary
Concomitant
Mental Impairment 2/16/2008 6/12/2008 United States
Primary
Concomitant
Weight Increased 5/1/2007 Female 292 lb 6/12/2008 United States
Primary
Concomitant
Serotonin Syndrome Other Serious 65 Female 7/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Loss Poor Other Serious 7/11/2002 45 Female 7/9/2008 United Kingdom
Primary
Concomitant
Overdose Death 1/25/2007 60 Male 7/15/2008 United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 75 Female 7/25/2008 Other Health Professional Germany
Primary
Concomitant
Overdose Death 1/25/2007 60 Male 213 lb 7/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Serotonin Syndrome Other Serious 65 Female 7/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Spinal Muscular Atrophy Other Serious 67 Male 8/7/2008 Other Health Professional Canada
Primary
Concomitant
Somnolence Other Serious 65 Female 8/15/2008 United Kingdom
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 7/17/2008 Female 97 lb 9/5/2008 Belgium
Primary
Concomitant
Respiratory Failure Hospitalization 12/27/2006 Female 9/15/2008 Physician United States
Primary
Secondary
Concomitant
Somnambulism Other Serious 9/1/2008 Male 247 lb 9/24/2008 United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 5/28/2008 Male 188 lb 9/22/2008 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 9/1/2006 55 Female 10/1/2008 Consumer United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 66 Male 10/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Diabetes Mellitus Inadequate Control Other Serious 66 Male 10/14/2008 Physician United Kingdom
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 66 Male 10/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Diabetes Mellitus Inadequate Control Other Serious 66 Male 10/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Diabetes Mellitus Inadequate Control Other Serious 66 Male 10/17/2008 Consumer United Kingdom
Primary
Secondary
Diarrhoea Male 11/3/2008 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 12/27/2006 Female 11/13/2008 Physician United States
Primary
Secondary
Concomitant
Confusional State Other Serious 10/24/2008 75 Female 11/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Death 1/26/2005 Male 11/24/2008 Consumer United States
Primary
Secondary
Concomitant
Muscle Spasms 9/4/2008 Female 11/26/2008 United States
Primary
Concomitant
Back Pain 10/2/2008 Female 11/26/2008 United States
Primary
Concomitant
Sensory Disturbance 11/5/2008 Female 11/26/2008 United States
Primary
Concomitant
Medication Error 11/18/2008 11/26/2008 Pharmacist United States
Primary
Secondary
Upper Limb Fracture 1/1/2006 Female 12/9/2008 Consumer
Primary
Concomitant
Nausea 8/30/2008 Female 12/12/2008 United States
Primary
Concomitant
Hepatitis Other Serious 69 Female 12/19/2008 Other Health Professional United States
Primary
Concomitant
Accidental Exposure Other Serious 51 Male 12/29/2008 Other Health Professional Germany
Primary
Secondary
Accidental Exposure Other Serious 51 Male 12/29/2008 Other Health Professional Germany
Primary
Secondary
Renal Failure Death 1/26/2005 Male 1/20/2009 Consumer United States
Primary
Secondary
Concomitant
Urticaria 10/29/2008 29 Female 2/9/2009 Consumer United States
Primary
Secondary
Concomitant
Tension 8/19/2008 49 Male 2/9/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/4/2009 61 Female 174 lb 2/9/2009 Physician United States
Primary
Concomitant
Ventricular Septal Defect Hospitalization 1/26/2005 Male 2/16/2009 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 12/27/2006 Female 3/3/2009 Physician United States
Primary
Secondary
Concomitant
Injection Site Pruritus 12/1/2008 Female 165 lb 3/14/2009 Physician United States
Primary
Concomitant
Insomnia Hospitalization 12/15/2006 53 Female 3/17/2009 Korea, Democratic People's Republic Of
Primary
Concomitant
Speech Disorder Other Serious 1/1/2007 Male 216 lb 4/1/2009 Consumer Netherlands
Primary
Concomitant
Suicidal Ideation Other Serious 10/1/1997 42 Male 236 lb 4/3/2009 United States
Primary
Concomitant
Ventricular Septal Defect Congenital Anomaly Male 4/15/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 5/21/2006 65 Male 4/17/2009 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 1/1/2001 54 Male 215 lb 4/27/2009 Other Health Professional United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 7/17/2008 Female 97 lb 4/28/2009 Belgium
Primary
Concomitant
Lipase Increased Required Intervention 75 Female 5/1/2009 Other Health Professional Italy
Primary
Concomitant
Syncope Hospitalization 2/15/2009 73 Female 141 lb 5/18/2009 United States
Primary
Concomitant
Pulmonary Congestion Other Serious 65 Male 157 lb 6/25/2009 Physician Portugal
Primary
Concomitant
Ventricular Septal Defect Congenital Anomaly Male 6/30/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/8/2009 74 Female 6/25/2009 Other Health Professional Netherlands
Primary
Concomitant
Diabetes Mellitus Hospitalization 7/17/2008 Female 97 lb 7/2/2009 Belgium
Primary
Concomitant
Renal Dysplasia Congenital Anomaly 10/11/2004 Female 8 lb 7/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Product Quality Issue Disability 4/1/2009 64 Male 7/2/2009 United Kingdom
Primary
Concomitant
Interacting
Transient Ischaemic Attack Hospitalization 6/6/2009 54 Male 181 lb 7/9/2009 Physician United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/6/2002 32 Male 154 lb 7/10/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 59 Female 155 lb 7/16/2009 United States
Primary
Concomitant
Breast Cancer Other Serious 7/1/2008 62 Female 7/20/2009 Pharmacist South Africa
Primary
Concomitant
Vomiting Hospitalization Female 7/15/2009 Other Health Professional Netherlands
Primary
Concomitant
Somnolence 6/16/2008 Male 8/6/2009 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Death 86 Male 8/16/2009 Lawyer United States
Primary
Concomitant
Toxic Skin Eruption Hospitalization 5/21/2009 57 Female 8/20/2009 Other Health Professional France
Primary
Secondary
Flushing 6/1/2009 Male 210 lb 8/23/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 1/1/2007 Female 8/25/2009 Physician United States
Primary
Concomitant
Flushing Male 256 lb 8/29/2009 United States
Primary
Concomitant
Product Odour Abnormal 8/26/2009 64 Female 8/28/2009 Pharmacist United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 10/14/2007 Female 9/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Death Female 9/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Fibrillation Death 86 Male 9/15/2009 United States
Primary
Concomitant
Weight Gain Poor 1/10/2005 48 Male 200 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Obesity 1/1/2001 35 Female 195 lb 9/23/2009 United States
Primary
Concomitant
Hypothyroidism Other Serious 2/1/2004 39 Female 288 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 86 Male 136 lb 9/25/2009 United States
Primary
Concomitant
Thrombin Time Prolonged Other Serious 80 Female 10/12/2009 Physician Netherlands
Primary
Concomitant
Wheezing Hospitalization 1/26/2005 Male 7 lb 10/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 81 Male 136 lb 10/27/2009 United States
Primary
Concomitant
Myocardial Infarction Death 7/12/2009 Female 12/1/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Life Threatening 8/1/2009 Female 12/23/2009 Physician Canada
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 11/1/2009 Male 2/2/2010 Physician United Kingdom
Primary
Concomitant
Dementia Alzheimer's Type Other Serious 3/26/2009 86 Female 110 lb 2/23/2010 Consumer Brazil
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2003 Male 3/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 59 Female 155 lb 4/19/2010 United States
Primary
Concomitant
Stomatitis Hospitalization 7/8/2008 60 Male 177 lb 4/16/2010 Lawyer United States
Primary
Concomitant
Hyperglycaemia Other Serious 60 Female 4/26/2010 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 77 Female 5/4/2010 Consumer United States
Primary
Concomitant
Off Label Use Hospitalization 3/2/2010 59 Female 5/6/2010 Physician France
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2006 59 Male 177 lb 5/12/2010 Lawyer United States
Primary
Concomitant
Parathyroid Tumour Benign Hospitalization 65 Female 254 lb 6/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Laboratory Test Abnormal Hospitalization 5/23/2010 74 Female 205 lb 5/31/2010 Pharmacist United States
Primary
Concomitant
Somnolence Hospitalization 65 Female 254 lb 6/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Parathyroid Tumour Benign Hospitalization 65 Female 254 lb 6/9/2010 United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 7/1/2006 59 Male 177 lb 6/21/2010 Lawyer United States
Primary
Concomitant
Weight Increased 1/1/2007 63 Male 305 lb 7/9/2010 Consumer United States
Primary
Concomitant
Renal Disorder Other Serious 11/1/2006 56 Male 250 lb 7/29/2010 Physician United States
Primary
Concomitant
Sleep Disorder Male 206 lb 7/30/2010 Consumer United States
Primary
Concomitant
Insomnia 7/1/2008 70 Male 198 lb 7/30/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 50 Male 8/9/2010 Consumer United States
Primary
Concomitant
Panic Attack 60 Female 8/9/2010 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 8/3/2010 48 Female 154 lb 8/12/2010 Pharmacist United States
Primary
Concomitant
Suicidal Ideation Hospitalization 77 Female 8/18/2010 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/30/2010 78 Male 8/23/2010 Brazil
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 9/1/2009 75 Female 9/1/2010 Consumer France
Primary
Secondary
Pneumonia Hospitalization 5/30/2010 78 Male 8/31/2010 Brazil
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/1/2010 75 Female 9/7/2010 Other Health Professional Germany
Primary
Secondary
Weight Decreased Other Serious 9/1/2009 75 Female 9/8/2010 Other Health Professional France
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/24/2006 72 Male 9/20/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 4/1/2010 63 Male 9/27/2010 Consumer France
Primary
Concomitant
Parkinsonism Other Serious 5/1/2010 80 Male 10/1/2010 Physician Spain
Primary
Concomitant
Rash Other Serious 3/20/2008 57 Female 10/11/2010 Physician United States
Primary
Concomitant

Drug Data