Metformin Hcl combined with Paracetamol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pruritus Death 7/22/2004 Male 187 lb 1/25/2006 United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 6/6/2002 89 Female 141 lb 1/26/2006 United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 10/14/2005 72 Female 2/3/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Swelling Disability 46 Male 254 lb 6/19/2006 Physician United Kingdom
Primary
Concomitant
Nervous System Disorder Other Serious 58 Female 176 lb 7/14/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Oesophageal Haemorrhage Hospitalization 7/8/2006 Female 105 lb 1/22/2007 Consumer Canada
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 7/15/2003 Female 186 lb 2/8/2007 Lawyer United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 9/1/2006 32 Female 192 lb 2/15/2007 Consumer United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious Female 3/1/2007 Pharmacist United Kingdom
Primary
Concomitant
Chest Pain Other Serious 8/15/2006 Female 137 lb 4/10/2007 Physician United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 3/2/2007 74 Male 4/13/2007 Other Health Professional France
Primary
Concomitant
Interacting
Haemorrhagic Stroke Hospitalization 3/27/2007 74 4/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 3/2/2007 74 Male 4/26/2007 Other Health Professional France
Primary
Concomitant
Interacting
Renal Failure Hospitalization 3/2/2007 74 Male 4/27/2007 Other Health Professional France
Primary
Concomitant
Interacting
Skin Ulcer Life Threatening 4/30/2007 Consumer United Kingdom
Primary
Concomitant
Rash Hospitalization 4/9/2004 65 Female 5/3/2007 Consumer United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 3/4/2006 66 Female 5/16/2007 Consumer Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 4/19/2007 78 5/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/30/2007 Female 263 lb 5/22/2007 Consumer Canada
Primary
Concomitant
Oral Candidiasis Hospitalization 6/8/2006 72 Male 132 lb 5/25/2007 United Kingdom
Primary
Secondary
Concomitant
Death Death 3/3/2007 Female 108 lb 5/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 3/3/2007 Female 108 lb 5/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperaesthesia Hospitalization 62 Male 159 lb 5/24/2007 Belgium
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 5/22/2007 6/4/2007 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Hospitalization 4/30/2007 Female 263 lb 6/9/2007 Physician Canada
Primary
Concomitant
Cardiac Failure Hospitalization 8/15/2006 Female 150 lb 6/13/2007 Physician United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 5/22/2007 Female 6/20/2007 Pharmacist United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 5/22/2007 Female 6/22/2007 Pharmacist United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 7/16/2006 Male 293 lb 7/16/2007 United Kingdom
Primary
Concomitant
Drug Interaction Death 78 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Somnolence Other Serious Female 8/24/2007 Physician Ireland
Primary
Concomitant
Rib Fracture Hospitalization 7/18/2007 76 Female 238 lb 8/31/2007 Consumer United Kingdom
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/6/2007 Consumer United Kingdom
Primary
Concomitant
Gait Disturbance Other Serious 7/27/2007 83 128 lb 9/6/2007 Physician United Kingdom
Primary
Concomitant
Platelet Count Increased Other Serious 6/23/2007 50 Male 320 lb 9/13/2007 Physician United Kingdom
Primary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 9/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 1/1/2007 73 Female 9/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/18/2007 Physician United Kingdom
Primary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 9/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 10/4/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Angina Unstable Other Serious 3/3/2007 64 Male 196 lb 11/15/2007 Physician Spain
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 5/22/2007 Female 12/10/2007 Pharmacist United Kingdom
Primary
Concomitant
Myositis Life Threatening 11/14/2007 46 Male 12/28/2007
Primary
Secondary
Concomitant
Hip Fracture Hospitalization 12/16/2007 Female 1/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Formication Hospitalization 2/26/2007 51 Male 1/17/2008
Primary
Secondary
Concomitant
Spinal Cord Compression Other Serious 77 Male 1/23/2008 Other Health Professional Germany
Primary
Secondary
Vomiting Life Threatening 1/1/2008 68 Male 198 lb 1/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 7/16/2006 Male 293 lb 2/6/2008 United Kingdom
Primary
Concomitant
Vision Blurred Hospitalization 11/17/2007 Female 2/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/19/2007 2/11/2008 Physician Australia
Primary
Concomitant
Renal Failure Life Threatening 77 Male 2/19/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Rash Hospitalization 7/17/2006 Male 293 lb 2/26/2008 United Kingdom
Primary
Concomitant
Death Death 3/15/2008 61 Female 3/21/2008 Netherlands
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 51 Female 4/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Gastric Ulcer Perforation Life Threatening 2/29/2008 54 Female 4/17/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/18/2008 United States
Primary
Concomitant
Rash Pustular Hospitalization 4/10/2007 Male 146 lb 4/18/2008 United Kingdom
Primary
Concomitant
Myocardial Ischaemia Life Threatening 8/30/2005 Male 139 lb 4/22/2008 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 3/12/2007 Male 4/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/30/2008 United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 1/19/2008 Male 5/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Myocardial Infarction Death 4/23/2008 Male 172 lb 5/2/2008 Physician Netherlands
Primary
Concomitant
Hypertension Other Serious 4/1/2008 63 Male 5/1/2008 Physician Spain
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/9/2008 United States
Primary
Concomitant
Hyperglycaemia Hospitalization 67 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 6/8/2006 Male 132 lb 8/4/2008 United Kingdom
Primary
Secondary
Concomitant
Retching Other Serious 11/12/2008 Female 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 1/18/2009 65 Male 223 lb 2/9/2009 Physician United Kingdom
Primary
Concomitant
Pneumonia Other Serious 6/9/2008 Female 141 lb 2/13/2009 United Kingdom
Primary
Concomitant
Hypertension Other Serious 12/28/2008 Female 159 lb 2/19/2009 Consumer United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 3/2/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/17/2008 Female 120 lb 3/3/2009 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 5/1/2008 67 Female 141 lb 3/13/2009 Consumer Brazil
Primary
Concomitant
Bronchospasm Other Serious 2/10/2009 58 Female 177 lb 3/13/2009 Physician United Kingdom
Primary
Concomitant
Agranulocytosis Other Serious 1/12/2009 69 Female 143 lb 3/16/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 1/12/2009 3/16/2009 Physician Germany
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 1/12/2009 69 Female 3/16/2009 Physician Germany
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 1/12/2009 3/30/2009 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Other Serious Female 4/2/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulse Pressure Decreased Disability 50 Female 192 lb 4/3/2009 Physician United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 3/1/2009 Male 220 lb 4/9/2009 Consumer United Kingdom
Primary
Concomitant
Pneumonia Other Serious 6/9/2008 Female 141 lb 4/13/2009 United Kingdom
Primary
Concomitant
Diarrhoea Other Serious Female 4/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Other Serious Female 4/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Other Serious Female 4/23/2009 United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 3/1/2009 Male 220 lb 4/29/2009 Consumer United Kingdom
Primary
Concomitant
Retching Other Serious 11/12/2008 Female 5/8/2009 Consumer United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 11/5/2008 67 Female 181 lb 5/13/2009 Other Health Professional Finland
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 5/29/2009 Consumer United States
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 1/12/2009 69 5/29/2009 Physician Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 2/16/2009 Male 222 lb 6/3/2009 Consumer United Kingdom
Primary
Concomitant
Agranulocytosis Life Threatening 1/12/2009 69 Female 6/15/2009 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/24/2009 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Other Serious 6/9/2009 75 Female 157 lb 6/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Other Serious 4/24/2009 Female 6/23/2009
Primary
Secondary
Concomitant
Upper Airway Obstruction Death 12/16/2008 82 Male 6/30/2009 Pharmacist United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 6/3/2009 Female 7/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Surgery Other Serious 1/1/2009 Male 7/8/2009 Pharmacist Germany
Primary
Concomitant
Lacunar Infarction Hospitalization 6/24/2009 85 Female 7/8/2009 Physician Spain
Primary
Concomitant
Influenza Other Serious 7/2/2009 Female 148 lb 7/15/2009 Other Health Professional Chile
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/7/2009 Female 7/15/2009 United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 7/16/2009 Consumer United States
Primary
Secondary
Concomitant
Influenza Other Serious 7/2/2009 Female 148 lb 7/21/2009 Other Health Professional Chile
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2008 54 Female 8/13/2009 Brazil
Primary
Secondary
Concomitant
Delirium Hospitalization 8/18/2009 Female 196 lb 8/28/2009 Netherlands
Primary
Secondary
Concomitant
Upper Airway Obstruction Death 12/16/2008 82 Male 8/26/2009 Pharmacist United Kingdom
Primary
Concomitant
Vision Blurred Disability 1/1/2009 65 Female 8/31/2009
Primary
Secondary
Concomitant
Delirium Hospitalization 8/18/2009 Female 196 lb 9/14/2009 Netherlands
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 2/1/2009 65 Female 9/17/2009 Physician Denmark
Primary
Concomitant
Sepsis Other Serious 71 Female 9/21/2009 Physician United Kingdom
Primary
Secondary
Urinary Retention Hospitalization 9/10/2009 Male 250 lb 9/22/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/1/2009 71 Male 181 lb 9/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 71 Female 10/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 71 Female 10/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Other Serious 71 10/9/2009 Physician United Kingdom
Primary
Secondary
Myositis Life Threatening 11/14/2007 4 Male 10/23/2009 United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious 7/6/2009 Female 123 lb 11/6/2009 Physician Malaysia
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/7/2008 66 Male 11/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 11/10/2009 Consumer United States
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 5/1/2008 66 Male 139 lb 11/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urine Odour Abnormal Other Serious Female 11/18/2009 Pharmacist France
Primary
Concomitant
Gastritis Hospitalization 10/23/2009 Male 125 lb 11/19/2009 Physician Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/14/2007 Male 188 lb 11/20/2009 Physician New Zealand
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Death 8/1/2009 Male 207 lb 11/23/2009 United Kingdom
Primary
Concomitant
Haematuria Hospitalization 9/1/2008 Male 11/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Polyarthritis Other Serious 9/19/2007 Male 11/30/2009 Physician Netherlands
Primary
Concomitant
Haemorrhage Other Serious 10/8/2009 Male 12/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Other Serious 4/1/2008 63 Male 12/1/2009 Physician Spain
Primary
Concomitant
Hypoglycaemia Life Threatening 11/19/2009 71 Male 12/7/2009 Netherlands
Primary
Concomitant
Melaena Other Serious 11/19/2009 71 Male 12/8/2009 Netherlands
Primary
Concomitant
Gastritis Hospitalization 10/23/2009 Male 125 lb 12/8/2009 Physician United States
Primary
Secondary
Concomitant
Melaena Other Serious 11/19/2009 71 Male 12/10/2009 Netherlands
Primary
Concomitant
Hiatus Hernia Hospitalization 10/23/2009 Male 125 lb 12/10/2009 Physician Brazil
Primary
Secondary
Concomitant
Jugular Vein Thrombosis Hospitalization 4/1/2007 Female 226 lb 12/11/2009 Physician Netherlands
Primary
Secondary
Concomitant
Death Death 10/31/2009 Female 12/11/2009 Consumer United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 63 Male 1/6/2010 Other Health Professional Austria
Primary
Secondary
Vomiting Hospitalization 8/23/2009 1/6/2010 Physician Netherlands
Primary
Secondary
Concomitant
Melaena Other Serious 11/19/2009 71 Male 1/8/2010 Netherlands
Primary
Concomitant
Melaena Other Serious 11/19/2009 71 Male 1/14/2010 Netherlands
Primary
Concomitant
Renal Impairment Other Serious 63 Male 1/11/2010
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/1/2009 83 Female 158 lb 1/15/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 1/15/2008 70 Female 154 lb 1/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urethral Cancer Other Serious 63 Male 231 lb 1/16/2010 United States
Primary
Secondary
Renal Failure Other Serious 1/11/2010 Male 1/29/2010 Physician France
Primary
Concomitant
Urinary Retention Hospitalization 9/10/2009 Male 250 lb 2/24/2010 Physician United Kingdom
Primary
Concomitant
Rib Fracture Hospitalization 7/18/2007 76 Female 238 lb 2/25/2010 Physician United Kingdom
Primary
Concomitant
Skin Exfoliation Hospitalization 12/24/2009 70 Male 2/23/2010 France
Primary
Concomitant
Urine Output Decreased Hospitalization 6/2/2009 Male 3/15/2010 United Kingdom
Primary
Concomitant

Drug Data