Metformin Hcl combined with Nph Insulin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Other Serious 12/12/2005 78 Male 151 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Hospitalization 3/18/2006 64 Male 182 lb 4/3/2006 Pharmacist United States
Primary
Secondary
Blood Glucose Increased 3/15/2006 77 Male 188 lb 4/17/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/30/2006 79 Male 167 lb 7/24/2006 United States
Primary
Concomitant
Blood Glucose Increased 4/8/2006 69 Male 160 lb 7/19/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased 4/25/2006 58 Female 7/19/2006 Consumer United States
Primary
Concomitant
Weight Decreased 6/1/2006 45 Male 250 lb 7/19/2006 Consumer United States
Primary
Concomitant
Feeling Abnormal Female 7/19/2006 Consumer United States
Primary
Concomitant
Supraventricular Extrasystoles Hospitalization 4/8/2006 78 Male 154 lb 9/11/2006 Physician France
Primary
Secondary
Concomitant
Drug Effect Decreased 1/1/2006 Male 300 lb 7/19/2006 Consumer United States
Primary
Concomitant
Weight Decreased 5/1/2006 Female 314 lb 7/19/2006 Consumer United States
Primary
Concomitant
Gastroenteritis Viral 5/7/2006 66 Female 205 lb 7/19/2006 Consumer United States
Primary
Concomitant
Medication Error Male 7/19/2006 Consumer United States
Primary
Concomitant
Drug Ineffective 6/10/2006 51 Female 225 lb 7/19/2006 Consumer United States
Primary
Concomitant
Erectile Dysfunction Other Serious 1/1/2005 68 Male 216 lb 9/28/2006 Pharmacist Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 8/2/2006 53 Male 120 lb 9/18/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Life Threatening 1/23/2006 71 Male 187 lb 11/1/2006 Physician Germany
Primary
Concomitant
Visual Disturbance Other Serious 44 Male 11/3/2006 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 9/1/2006 Male 11/8/2006 Physician United States
Primary
Secondary
Concomitant
Weight Fluctuation 1/1/2002 67 Female 11/30/2006 Other Health Professional United States
Primary
Concomitant
Wolff-parkinson-white Syndrome Hospitalization 11/17/2006 49 Male 215 lb 12/14/2006 United States
Primary
Concomitant
Synovitis Hospitalization 10/30/2006 71 Female 1/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased 12/1/2005 58 Female 350 lb 10/16/2006 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 5/31/2006 Female 160 lb 6/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/17/2006 73 Male 135 lb 12/19/2006 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 9/13/2006 71 Male 257 lb 9/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Swelling Hospitalization 2/8/2007 Female 5/30/2007 Physician United States
Primary
Concomitant
Swelling Hospitalization 2/8/2007 Female 5/30/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2004 Female 6/8/2007 Lawyer United States
Primary
Secondary
Concomitant
Chills 2/7/2007 67 Female 4/10/2007 Consumer United States
Primary
Concomitant
Nausea 1/10/2007 71 Male 4/10/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2004 Female 8/8/2007 Lawyer United States
Primary
Secondary
Concomitant
Retinal Disorder Other Serious Female 8/30/2007 Physician Puerto Rico
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 Female 8/31/2007 Lawyer United States
Primary
Secondary
Concomitant
Contrast Media Allergy Life Threatening 7/16/2007 43 Male 273 lb 8/30/2007 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 Female 9/18/2007 Lawyer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 11/3/2003 Female 10/11/2007 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 11/1/2003 Female 11/28/2007 Consumer United States
Primary
Secondary
Concomitant
Unintended Pregnancy Other Serious 8/1/2005 Female 97 lb 1/29/2008 Consumer Brazil
Primary
Concomitant
Unintended Pregnancy Other Serious 1/1/2007 Female 97 lb 2/22/2008 Consumer Brazil
Primary
Concomitant
Blood Glucose Fluctuation 1/1/2005 73 Female 148 lb 2/25/2008 Consumer United States
Primary
Secondary
Concomitant
Toothache Hospitalization 10/8/2007 57 Female 3/17/2009 Korea, Republic Of
Primary
Concomitant
Myocardial Ischaemia Hospitalization 3/11/2003 34 Male 276 lb 5/26/2009 Lawyer United States
Primary
Concomitant
Pulmonary Malformation Death 2/13/2009 5/28/2009 Physician Algeria
Primary
Concomitant
Myocardial Ischaemia Hospitalization 3/1/2003 34 Male 276 lb 5/29/2009 Pharmacist United States
Primary
Concomitant
Breast Cancer Required Intervention 4/12/2003 63 Female 183 lb 5/19/2009 Consumer United States
Primary
Secondary
Concomitant
Sensation Of Heaviness Other Serious 41 Female 6/23/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/1/2001 16 Female 200 lb 7/9/2009 United States
Primary
Concomitant
Diabetic Retinopathy Other Serious 10/1/2004 41 Male 152 lb 7/21/2009 United States
Primary
Secondary
Concomitant
Blood Glucose Increased Male 8/22/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 6/1/2008 55 Male 174 lb 8/26/2009 Consumer Brazil
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1999 Female 10/23/2009 Physician United States
Primary
Concomitant
Muscular Weakness 1/1/2005 Female 226 lb 11/24/2009 Consumer United States
Primary
Concomitant
Drug Exposure During Pregnancy Hospitalization 1/27/2008 Female 12/1/2009 Consumer United States
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 1/1/2009 Male 1/5/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2009 Female 165 lb 1/8/2010 Consumer Brazil
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/1999 Female 197 lb 2/5/2010 Physician United States
Primary
Concomitant
Hypokalaemia Life Threatening 11/24/2009 66 Female 209 lb 2/10/2010 Consumer United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 11/24/2009 66 Female 209 lb 2/23/2010 Consumer United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 4/6/2010 United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2009 57 Male 4/12/2010 Other Health Professional United States
Primary
Concomitant
Wound Other Serious 1/1/2010 66 Female 4/13/2010 Physician Canada
Primary
Concomitant
Visual Impairment Other Serious 5/22/2010 49 Male 194 lb 6/18/2010 Consumer Switzerland
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 1/13/2010 54 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Swelling Other Serious 11/1/2007 47 Male 320 lb 6/29/2010 Lawyer United States
Primary
Concomitant
Product Quality Issue 6/17/2010 66 Female 151 lb 6/28/2010 Consumer United States
Primary
Concomitant
Erectile Dysfunction Other Serious 10/1/2004 41 Male 152 lb 7/2/2010 United States
Primary
Secondary
Concomitant
Tumour Necrosis Other Serious 1/1/2010 63 Male 205 lb 7/12/2010 Brazil
Primary
Concomitant
Product Quality Issue 6/17/2010 66 Female 151 lb 7/19/2010 Consumer United States
Primary
Concomitant
Frustration 1/1/2008 64 Male 266 lb 7/31/2010 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 3/29/2010 56 Male 181 lb 8/13/2010 Physician Turkey
Primary
Secondary
Concomitant
Quality Of Life Decreased Death 68 Male 279 lb 10/19/2010 Pharmacist United States
Primary
Concomitant
Infection Hospitalization 10/17/2010 67 Female 11/14/2010 Consumer Canada
Primary
Concomitant
Varicose Ulceration Hospitalization 3/1/2009 12/31/2010 Consumer Colombia
Primary
Secondary
Concomitant
Varicose Ulceration Other Serious 3/1/2009 1/5/2011 Consumer Colombia
Primary
Secondary
Concomitant
Device Dislocation Other Serious 4/1/2010 57 Female 161 lb 1/6/2011 Consumer Brazil
Primary
Concomitant
Oesophageal Candidiasis Other Serious 2/3/2011 42 Male 2/11/2011 Other Health Professional Mexico
Primary
Secondary
Concomitant
Pain Other Serious 1/7/2005 51 Female 230 lb 3/24/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/7/2005 51 Female 230 lb 3/24/2011 Consumer United States
Primary
Concomitant
Application Site Swelling Other Serious 10/1/2010 36 Female 5/3/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Drug Hypersensitivity 7/2/2010 53 Female 367 lb 5/13/2011 Physician United States
Primary
Concomitant
Feeling Abnormal Other Serious 1/1/2005 51 Male 207 lb 5/17/2011 Consumer Brazil
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2005 51 Male 207 lb 5/19/2011 Consumer Brazil
Primary
Concomitant
Puncture Site Haemorrhage Other Serious 8/12/2010 67 Male 243 lb 5/25/2011 Other Health Professional Canada
Primary
Concomitant
Scar Other Serious Female 209 lb 5/31/2011 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 5/16/2011 62 Male 248 lb 5/25/2011 Pharmacist United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 1/14/2011 68 Male 6/16/2011 Consumer United States
Primary
Secondary
Concomitant
Gait Disturbance Disability 4/25/2008 68 Female 169 lb 4/17/2011 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 5/16/2011 62 Male 248 lb 6/17/2011 Pharmacist United States
Primary
Concomitant
Toxoplasma Serology Positive Hospitalization 5/7/2005 58 Male 174 lb 6/29/2011 United States
Primary
Secondary
Concomitant
Scar Other Serious 1/1/2009 63 Female 209 lb 6/29/2011 Consumer United States
Primary
Secondary
Concomitant
Injury Other Serious 1/7/2005 51 Female 230 lb 7/6/2011 Consumer United States
Primary
Concomitant
Acute Respiratory Failure Other Serious 1/14/2011 68 Male 7/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/14/2011 68 Male 7/18/2011 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Required Intervention 5/20/2005 61 Male 200 lb 7/11/2011 Lawyer United States
Primary
Concomitant
Haematoma Disability 5/16/2011 62 Male 248 lb 7/22/2011 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/14/2011 68 Male 8/18/2011 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 1/11/2011 68 Male 8/24/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/11/2011 68 Male 8/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Retroperitoneal Neoplasm Other Serious 8/24/2011 69 Male 130 lb 9/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 53 Male 9/26/2011 Brazil
Primary
Secondary
Infectious Peritonitis Hospitalization 8/24/2011 69 Male 130 lb 9/30/2011 Consumer United States
Primary
Secondary
Concomitant
Iga Nephropathy Hospitalization 6/29/2010 24 Female 115 lb 10/24/2011 Brazil
Primary
Secondary
Concomitant
Nonspecific Reaction Female 10/27/2011 Other Health Professional United States
Primary
Concomitant
Albuminuria Other Serious 54 Female 355 lb 10/31/2011 Physician Brazil
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 5/1/2010 33 Female 188 lb 10/31/2011 Physician Brazil
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 1/11/2011 68 Male 11/1/2011 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Death 9/21/2006 59 Male 196 lb 11/1/2011 Lawyer United States
Primary
Concomitant
Hypersensitivity Female 11/1/2011 Other Health Professional United States
Primary
Concomitant
Blood Pressure Increased Other Serious 53 Male 11/2/2011 Physician Brazil
Primary
Secondary
Cardiac Disorder Other Serious 3/2/2006 58 Male 200 lb 11/3/2011 Consumer United States
Primary
Concomitant
Microalbuminuria Other Serious 5/1/2010 33 Female 188 lb 11/2/2011 Physician
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 53 Male 194 lb 11/9/2011 Physician Brazil
Primary
Secondary
Pancreatitis Acute Life Threatening 1/11/2011 68 Male 11/10/2011 Consumer United States
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 5/1/2010 33 Female 188 lb 11/13/2011 Physician Brazil
Primary
Secondary
Concomitant
Retroperitoneal Neoplasm Other Serious 8/24/2011 69 Male 130 lb 11/14/2011 Consumer United States
Primary
Secondary
Concomitant
Accidental Overdose Other Serious 10/25/2011 48 Female 141 lb 11/16/2011 Pharmacist Mexico
Primary
Secondary
Concomitant
Low Density Lipoprotein Increased Other Serious 5/1/2010 33 Female 188 lb 11/15/2011 Physician
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 10/19/2011 63 Male 11/22/2011 Physician Canada
Primary
Secondary
Polyarthritis Hospitalization 10/30/2006 71 Female 153 lb 12/1/2011 Physician United States
Primary
Secondary
Concomitant
Dizziness 10/21/2011 59 Female 12/5/2011 Other Health Professional United States
Primary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 68 Female 12/6/2011 Brazil
Primary
Secondary
Concomitant
Blood Urea Increased Other Serious 68 Female 12/6/2011 Brazil
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/4/2011 58 Male 190 lb 12/7/2011 Consumer Mexico
Primary
Concomitant
Nerve Injury Life Threatening 6/27/2011 61 189 lb 11/15/2011 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 10/19/2011 63 Male 12/8/2011 Physician Canada
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 2/3/2011 42 Male 12/13/2011 Other Health Professional Mexico
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 10/19/2011 63 Male 12/20/2011 Physician Canada
Primary
Secondary
Concomitant
Nausea Other Serious 12/6/2011 49 Male 269 lb 12/19/2011 Pharmacist United States
Primary
Concomitant
Parkinson's Disease Other Serious 1/1/2011 71 Female 159 lb 12/30/2011 Consumer Brazil
Primary
Secondary
Concomitant
Arrhythmia Other Serious Male 200 lb 12/30/2011 Lawyer United States
Primary
Concomitant
Asthenia 10/21/2011 59 Female 1/9/2012 Other Health Professional United States
Primary
Concomitant
Nonspecific Reaction 10/21/2011 59 Female 1/9/2012 Other Health Professional United States
Primary
Concomitant
Dyspnoea Hospitalization 10/19/2011 63 Male 1/10/2012 Physician Canada
Primary
Secondary
Concomitant
Nausea 10/21/2011 59 Female 1/11/2012 Other Health Professional United States
Primary
Concomitant
Arrhythmia Other Serious 9/29/2009 70 Male 260 lb 1/13/2012 Lawyer United States
Primary
Concomitant
Opportunistic Infection Life Threatening 1/11/2011 68 Male 1/27/2012 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 197 lb 1/25/2012 Lawyer United States
Primary
Concomitant
Psoriasis Other Serious 57 Female 243 lb 3/3/2012 Consumer Brazil
Primary
Concomitant
Pneumonia Aspiration Hospitalization 2/1/2012 51 Male 3/27/2012 United States
Primary
Secondary
Concomitant
Back Disorder Death 2/23/2012 75 Male 176 lb 3/29/2012 Consumer Brazil
Primary
Concomitant
Vomiting 3/6/2012 78 Male 4/6/2012 Pharmacist United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 2/1/2012 51 Male 4/16/2012 Physician United States
Primary
Secondary
Concomitant
Back Pain Death 10/19/2011 64 Male 4/26/2012 Physician Canada
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Hospitalization 8/19/2011 61 Female 323 lb 4/27/2012 Other Health Professional United States
Primary
Concomitant
Insomnia Other Serious 132 lb 4/27/2012 Consumer Brazil
Primary
Concomitant
Cervix Carcinoma Hospitalization 56 Female 291 lb 5/7/2012 Lawyer United States
Primary
Concomitant
Pneumonia Hospitalization 10/19/2011 64 Male 5/11/2012 Physician Canada
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 2/1/2012 51 Male 5/11/2012 United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 4/16/2012 61 Female 229 lb 5/21/2012 Other Health Professional Canada
Primary
Concomitant

Drug Data