Metformin Hcl combined with Nitroglycerin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatic Enzyme Abnormal Required Intervention 7/29/2005 67 Male 188 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Melaena Hospitalization 12/11/2003 77 Female 1/24/2006 Other Health Professional France
Primary
Secondary
Vomiting Other Serious 12/12/2005 78 Male 151 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Pulmonary Mass Other Serious 12/6/2005 59 Female 2/3/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Syncope Hospitalization 10/18/2005 66 Male 210 lb 10/19/2005 Pharmacist United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 12/28/2005 58 Male 418 lb 12/29/2005 Pharmacist United States
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Other Serious 12/6/2005 59 Female 2/16/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Male 200 lb 2/17/2006 United States
Primary
Concomitant
Stent Placement Other Serious 1/1/2004 60 Male 197 lb 3/14/2006 United States
Primary
Concomitant
Troponin Increased Other Serious 2/3/2006 68 Male 172 lb 3/15/2006 Physician Italy
Primary
Concomitant
Feeling Abnormal 2/1/2006 60 Male 290 lb 4/17/2006 Consumer United States
Primary
Concomitant
Vascular Occlusion Other Serious 80 Female 196 lb 7/5/2006 Physician United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 1/1/2006 Male 210 lb 8/24/2006 Consumer United States
Primary
Concomitant
Hypotension Other Serious 8/29/2006 81 Male 117 lb 8/29/2006 Pharmacist United States
Primary
Concomitant
Macular Oedema Other Serious 1/30/2006 74 Male 185 lb 10/12/2006 Pharmacist Australia
Primary
Concomitant
Pain In Extremity Other Serious Male 10/9/2006 France
Primary
Concomitant
Vision Blurred Other Serious 1/30/2006 74 Male 185 lb 10/17/2006 Pharmacist Australia
Primary
Concomitant
Vision Blurred Other Serious 1/30/2006 74 Male 185 lb 10/18/2006 Pharmacist Australia
Primary
Concomitant
Pharmaceutical Product Complaint 10/15/2006 62 Female 230 lb 10/16/2006 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 8/15/2006 81 Male 111 lb 9/18/2006 Pharmacist United States
Primary
Concomitant
Cough 1/1/2006 77 Male 10/30/2006 Consumer United States
Primary
Concomitant
Infusion Site Reaction Hospitalization 10/1/2006 70 Male 187 lb 12/10/2006 Other Health Professional United States
Primary
Concomitant
Visual Disturbance Other Serious 12/19/2006 Male 245 lb 12/28/2006 Consumer United States
Primary
Concomitant
Lung Neoplasm Malignant Life Threatening 7/1/2006 Male 185 lb 12/28/2006 Spain
Primary
Concomitant
Presyncope Other Serious Male 229 lb 11/14/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 1/7/2006 68 Female 151 lb 1/19/2007 Consumer United States
Primary
Concomitant
Haemorrhage Life Threatening 1/22/2007 76 Male 254 lb 1/26/2007 Pharmacist United States
Primary
Concomitant
Vomiting Life Threatening 10/1/2006 61 Male 250 lb 2/1/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/1/2006 61 Male 250 lb 2/2/2007 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 44 Female 2/13/2007 Consumer United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious Female 221 lb 2/16/2007 United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 1/1/2005 52 Female 150 lb 3/1/2007 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 1/1/2005 52 Female 150 lb 3/7/2007 Physician United States
Primary
Concomitant
Vomiting Life Threatening 9/15/2006 61 Male 250 lb 3/9/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/1/2006 61 Male 250 lb 3/20/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/1/2006 61 Male 250 lb 3/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Protein Urine Required Intervention 70 Male 2/23/2006 United States
Primary
Concomitant
Myalgia Hospitalization 8/19/2005 62 Female 211 lb 2/23/2006 Other Health Professional United States
Primary
Concomitant
Coronary Artery Occlusion Life Threatening 1/12/2007 72 Female 226 lb 3/21/2007 Other Health Professional United States
Primary
Concomitant
Protein Urine Required Intervention 7/21/2005 70 Male 189 lb 6/2/2006 United States
Primary
Concomitant
Dyspnoea Hospitalization 3/26/2007 Female 165 lb 3/26/2007 Pharmacist United States
Primary
Concomitant
Intentional Overdose Other Serious 71 Male 3/29/2007 Pharmacist Canada
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 7/1/2006 Male 150 lb 3/29/2007 Spain
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 10/1/2006 61 Male 250 lb 3/23/2007 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 9/1/2006 Female 186 lb 5/1/2007 Physician United States
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 3/20/2007 85 Male 4/24/2007 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious Female 221 lb 5/14/2007 United States
Primary
Concomitant
Hypotension Hospitalization 1/26/2007 59 Male 5/10/2007 Pharmacist United States
Primary
Concomitant
Vomiting Life Threatening 10/1/2006 61 Male 250 lb 5/16/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 10/1/2006 Male 250 lb 5/21/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/1/2006 59 Female 145 lb 5/17/2007 Consumer United States
Primary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious Male 3/28/2007 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 92 Male 6/12/2007 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 8/1/2006 59 Female 145 lb 6/5/2007 Consumer United States
Primary
Concomitant
Syncope Other Serious 6/6/2007 60 Female 6/14/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2006 68 Female 151 lb 6/20/2007 Consumer United States
Primary
Concomitant
Narcolepsy Other Serious 4/1/2007 Male 163 lb 6/22/2007 Physician Netherlands
Primary
Concomitant
Dyspnoea 1/13/2007 54 Male 6/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Other Serious 8/29/2006 56 Female 6/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Required Intervention 7/9/2007 47 Female 188 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Hospitalization 6/16/2007 73 Male 130 lb 7/23/2007 Physician Spain
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 53 Female 297 lb 8/13/2007 Consumer United States
Primary
Concomitant
Psoriasis Hospitalization 1/1/2004 57 Male 292 lb 8/13/2007 Consumer United States
Primary
Concomitant
Stent Placement Hospitalization Male 8/24/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2006 Female 8/27/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/1/2007 Female 220 lb 9/11/2007 Physician United States
Primary
Concomitant
Haematochezia Other Serious 4/1/2007 Female 9/11/2007 Consumer United States
Primary
Concomitant
Onychoclasis 74 Female 144 lb 10/2/2007 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 3/1/2007 Female 229 lb 10/4/2007 Consumer United States
Primary
Concomitant
Rash Pruritic 12/1/2006 Female 210 lb 8/6/2007 Pharmacist United States
Primary
Concomitant
Myalgia Other Serious 79 Female 10/19/2007 Pharmacist Canada
Primary
Concomitant
Pruritus 11/7/2006 67 Female 11/13/2007 Consumer United States
Primary
Concomitant
Blood Glucose Increased 9/4/2007 65 Male 11/16/2007 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 3/1/2007 Female 229 lb 12/11/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2001 68 Male 241 lb 12/11/2007 Consumer United States
Primary
Concomitant
Foreign Body Trauma Other Serious 1/1/2007 Female 12/12/2007 Pharmacist United States
Primary
Secondary
Concomitant
Nausea Hospitalization 8/1/2007 Male 220 lb 12/11/2007 Physician United States
Primary
Concomitant
Generalised Oedema Hospitalization 11/9/2007 Male 12/20/2007 Other Health Professional Norway
Primary
Concomitant
Weight Increased Hospitalization 7/1/2001 68 Male 241 lb 12/20/2007 Consumer United States
Primary
Concomitant
Hypotension Other Serious 71 Male 174 lb 12/21/2007 Other Health Professional Brazil
Primary
Secondary
Concomitant
Vomiting 5/1/2007 65 Female 10/8/2007 Consumer United States
Primary
Concomitant
Generalised Oedema Hospitalization 11/9/2007 Male 1/2/2008 Other Health Professional Norway
Primary
Concomitant
Vomiting 7/4/2007 57 Female 10/8/2007 Consumer United States
Primary
Concomitant
Haematochezia Other Serious 6/1/2007 Female 270 lb 1/14/2008 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2007 Male 1/17/2008 Consumer
Primary
Concomitant
Metabolic Acidosis Other Serious 68 Male 1/18/2008 Other Health Professional Germany
Primary
Secondary
Cholelithiasis Hospitalization 10/30/2007 49 Female 187 lb 1/18/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Death 68 Male 1/29/2008 Spain
Primary
Secondary
International Normalised Ratio Decreased Other Serious 11/1/2007 Female 295 lb 1/29/2008 Physician United States
Primary
Concomitant
Interacting
Renal Failure Other Serious 68 Male 2/1/2008 Other Health Professional United States
Primary
Secondary
Vomiting Death 68 Male 1/31/2008 Spain
Primary
Secondary
Weight Decreased Hospitalization 1/1/2007 Female 2/1/2008 Consumer United States
Primary
Concomitant
Metabolic Acidosis Death 68 Male 2/12/2008 Spain
Primary
Secondary
Urine Albumin/creatinine Ratio Increased Other Serious 12/1/2007 2/12/2008 Physician Canada
Primary
Concomitant
Ventricular Asystole Hospitalization 68 Male 2/11/2008 Spain
Primary
Secondary
Dyspnoea Life Threatening 1/5/2008 63 Female 198 lb 2/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 Male 221 lb 2/26/2008 Consumer United States
Primary
Concomitant
Toothache Hospitalization 10/8/2007 57 Female 2/25/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Weight Decreased 1/1/2006 70 Male 250 lb 1/10/2008 Consumer United States
Primary
Concomitant
Vomiting 8/1/2007 69 Male 1/10/2008 Consumer United States
Primary
Concomitant
Paraesthesia 9/27/2007 53 Female 145 lb 1/10/2008 Consumer United States
Primary
Concomitant
Ventricular Asystole Other Serious 68 Male 3/7/2008 Physician Spain
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 11/18/2007 62 Male 2/15/2008 United States
Primary
Concomitant
Arthritis 5/28/2007 66 Female 240 lb 6/14/2007 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2006 Male 245 lb 3/11/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 10/8/2007 57 Female 3/6/2008 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 68 Male 3/18/2008 Spain
Primary
Secondary
Renal Failure Other Serious 68 Male 3/18/2008 Other Health Professional United States
Primary
Secondary
Hyperkalaemia Other Serious 6/26/2006 83 Female 2/22/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 68 Male 3/20/2008 Spain
Primary
Secondary
Vomiting Hospitalization 10/8/2007 57 Female 3/25/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Renal Failure Other Serious 68 Male 3/31/2008 Spain
Primary
Secondary
Metabolic Acidosis Death 68 Male 4/3/2008 Other Health Professional Spain
Primary
Secondary
Metabolic Acidosis Other Serious 68 Male 4/7/2008 Consumer Spain
Primary
Secondary
Weight Decreased Hospitalization 1/1/2007 Female 247 lb 4/2/2008 Consumer United States
Primary
Concomitant
Procedural Site Reaction Required Intervention 2/1/2006 50 Male 280 lb 4/3/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/9/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/1/2006 Female 4/7/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 68 Male 4/11/2008 Consumer Spain
Primary
Secondary
Weight Decreased Other Serious 2/1/2008 Male 201 lb 4/9/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/18/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/24/2008 Physician United States
Primary
Secondary
Concomitant
Vascular Occlusion Other Serious 3/27/2004 Male 4/18/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Female 247 lb 4/25/2008 Physician United States
Primary
Concomitant
Sudden Death Death 4/13/2008 77 Female 5/1/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/8/2007 57 Female 4/28/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2006 Male 245 lb 5/16/2008 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Other Serious 3/12/2008 66 Female 146 lb 5/19/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1990 62 Female 203 lb 5/20/2008 United States
Primary
Secondary
Concomitant
Nausea Other Serious 2/4/2008 Male 155 lb 5/23/2008 Physician Canada
Primary
Concomitant
Suicidal Ideation Other Serious 3/24/2008 Female 148 lb 5/30/2008 United States
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 6/10/2008 63 Female 229 lb 6/13/2008 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 3/24/2008 Female 148 lb 6/16/2008 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 1/5/2008 61 Female 167 lb 6/10/2008 United States
Primary
Concomitant
Glossitis 81 Female 124 lb 6/24/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/30/2005 Male 139 lb 6/27/2008 United States
Primary
Concomitant
Angina Pectoris Hospitalization 6/8/2008 Male 434 lb 6/27/2008 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/10/2007 60 Male 149 lb 6/23/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2008 Male 6/30/2008 Consumer United States
Primary
Concomitant
Ventricular Hypokinesia Life Threatening 8/30/2005 Male 139 lb 7/2/2008 Physician United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 7/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 4/8/2008 Male 321 lb 7/2/2008 Physician United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 7/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 4/1/2008 Male 321 lb 7/10/2008 Physician United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 7/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/18/2008 67 Male 187 lb 7/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 7/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1990 Female 220 lb 7/29/2008 United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 5/8/2008 56 Male 250 lb 7/24/2008 Consumer United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 194 lb 7/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data