Metformin Hcl combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Dehydration Hospitalization 11/19/2005 55 Male 236 lb 1/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/19/2005 55 Male 236 lb 1/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/19/2005 55 Male 236 lb 2/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/26/2006 67 Female 130 lb 2/10/2006 Physician Sweden
Primary
Concomitant
Vertigo Hospitalization 1/26/2006 67 Female 130 lb 2/24/2006 Physician Sweden
Primary
Concomitant
Weight Decreased Other Serious 64 Male 155 lb 7/5/2006 Physician United States
Primary
Concomitant
Snoring Life Threatening 6/26/2006 52 Female 306 lb 8/31/2006 Pharmacist United States
Primary
Concomitant
Nausea Hospitalization 9/25/2006 44 Male 283 lb 9/26/2006 Pharmacist United States
Primary
Concomitant
Pleural Effusion Hospitalization 9/10/2006 39 Female 217 lb 9/27/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Urinary Tract Infection Bacterial Required Intervention 6/30/2006 62 Female 9/21/2006 Physician United States
Primary
Secondary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 251 lb 10/16/2006 Consumer United States
Primary
Concomitant
Rash Hospitalization 9/22/2006 77 Male 128 lb 10/25/2006 Physician Australia
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 9/10/2006 39 Female 217 lb 10/24/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 9/1/2006 Male 11/8/2006 Physician United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/26/2006 67 Female 130 lb 11/7/2006 Physician Sweden
Primary
Concomitant
Malnutrition Hospitalization 1/1/2006 77 Male 132 lb 11/28/2006 Physician Canada
Primary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 255 lb 11/15/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/30/2006 39 Female 205 lb 11/20/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/30/2006 39 Female 205 lb 11/30/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Vertigo Hospitalization 1/26/2006 67 Female 130 lb 12/5/2006 Physician Sweden
Primary
Concomitant
Staphylococcal Infection Life Threatening 6/13/2006 39 Female 205 lb 12/12/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Malnutrition Hospitalization 1/1/2006 77 Male 132 lb 12/22/2006 Physician Canada
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/17/2006 60 Male 1/8/2007 Consumer Ireland
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/25/2006 69 Male 10/6/2006 United States
Primary
Secondary
Concomitant
Weight Fluctuation Hospitalization 67 Male 255 lb 1/18/2007 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/17/2006 60 Male 2/2/2007 Consumer Ireland
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 Female 154 lb 2/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting 1/1/2006 73 Female 11/10/2006 Consumer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/17/2006 60 Male 2/20/2007 Consumer Ireland
Primary
Secondary
Concomitant
Panic Reaction Other Serious 2/1/2007 Female 200 lb 2/27/2007 Consumer United States
Primary
Concomitant
Loss Of Consciousness Life Threatening 1/26/2006 69 Male 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 3/26/2007 Female 165 lb 3/26/2007 Pharmacist United States
Primary
Concomitant
Parkinson's Disease Death 68 Male 11/6/2006 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 3/1/2007 54 Female 3/26/2007 Physician Peru
Primary
Secondary
Concomitant
Nephrolithiasis Other Serious 1/1/2007 46 Male 5/11/2007 Pharmacist Canada
Primary
Concomitant
Vomiting Hospitalization 4/30/2007 Female 263 lb 5/22/2007 Consumer Canada
Primary
Concomitant
Vomiting Hospitalization 4/30/2007 Female 263 lb 6/9/2007 Physician Canada
Primary
Concomitant
Nephrolithiasis Other Serious 1/1/2007 46 Male 5/24/2007 Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 9/24/2006 Male 439 lb 5/15/2007 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/17/2006 60 Male 7/13/2007 Consumer Ireland
Primary
Secondary
Concomitant
Somnolence 59 Male 7/23/2007 Consumer United States
Primary
Concomitant
Pancreatic Carcinoma Death 9/1/2004 Male 126 lb 7/24/2007 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/17/2006 60 Male 8/1/2007 Consumer Ireland
Primary
Secondary
Concomitant
Unresponsive To Stimuli Disability 4/14/2007 68 Male 262 lb 7/30/2007 Pharmacist United States
Primary
Concomitant
Parkinsonism Hospitalization 5/19/2006 69 Male 8/3/2007 Pharmacist United States
Primary
Concomitant
Respiratory Failure Death 2/1/2007 59 Male 8/7/2007 Physician United States
Primary
Concomitant
Urine Output Decreased Hospitalization 2/19/2006 60 Male 8/15/2007 Consumer Ireland
Primary
Secondary
Concomitant
Hepatitis Death 1/1/2006 63 Male 123 lb 8/17/2007 Pharmacist Canada
Primary
Concomitant
Hepatitis Death 1/1/2006 63 Male 123 lb 8/20/2007 Pharmacist Canada
Primary
Concomitant
Methaemoglobinaemia Hospitalization 57 Male 8/20/2007
Primary
Secondary
Concomitant
Vomiting Other Serious Male 146 lb 8/30/2007 United States
Primary
Concomitant
Vomiting 4/19/2007 54 Male 7/11/2007 Consumer United States
Primary
Concomitant
Upper Extremity Mass Hospitalization 6/19/2007 Male 246 lb 10/9/2007 Canada
Primary
Concomitant
Vaginal Candidiasis Required Intervention 8/25/2007 70 Female 10/24/2007 Physician Canada
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/17/2006 60 Male 11/27/2007 Consumer Ireland
Primary
Secondary
Concomitant
Nausea Hospitalization 3/5/2007 62 Male 194 lb 3/22/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 11/9/2007 Female 225 lb 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Female 241 lb 12/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 12/1/2007 Male 200 lb 12/31/2007 Consumer United States
Primary
Concomitant
Stupor Hospitalization 52 Female 1/10/2008 Other Health Professional Australia
Primary
Concomitant
Stupor Hospitalization 52 Female 1/15/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Somnolence Other Serious 52 Female 1/23/2008
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/19/2006 60 Male 2/1/2008 Consumer Ireland
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious Male 2/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious Male 3/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/6/2008 76 Male 195 lb 3/7/2008 Other Health Professional United States
Primary
Concomitant
Cerebral Haemorrhage Other Serious 6/10/2007 Male 201 lb 4/4/2008 Physician United States
Primary
Secondary
Concomitant
Posturing Life Threatening 6/21/2007 68 Male 4/8/2008 Pharmacist United States
Primary
Secondary
Concomitant
Myocarditis Other Serious 3/1/2008 60 Male 4/9/2008 Physician United States
Primary
Concomitant
Spinal Fracture Other Serious 52 Male 4/25/2008 Consumer United States
Primary
Concomitant
Oesophagitis Hospitalization 12/26/2007 Male 5/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/27/2008 71 Male 185 lb 5/5/2008 Consumer United States
Primary
Secondary
Concomitant
Overdose Other Serious 1/1/2006 Female 6/30/2008 Consumer United States
Primary
Concomitant
Lactic Acidosis Life Threatening 1/10/2008 67 Male 7/7/2008
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 68 Female 7/8/2008 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 217 lb 7/18/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/15/2008 Male 192 lb 7/22/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 7/1/2008 63 Male 192 lb 7/28/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Death 7/15/2008 Male 192 lb 7/25/2008 Physician United States
Primary
Concomitant
Vomiting Death 7/24/2008 Male 192 lb 7/25/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 7/1/2008 63 Male 192 lb 7/30/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Life Threatening 1/10/2008 67 Female 8/1/2008 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 7/31/2008 United States
Primary
Secondary
Concomitant
Lactic Acidosis Life Threatening 1/10/2008 67 Male 8/7/2008
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 216 lb 8/11/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 216 lb 8/22/2008 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/28/2008 Female 270 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Hallucination, Visual Hospitalization 8/19/2008 61 Male 386 lb 8/20/2008 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 1/1/2006 Female 134 lb 9/19/2008 Physician United States
Primary
Concomitant
Trismus Other Serious 54 Male 9/24/2008 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 12/26/2007 Male 10/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 11/4/2008 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 1/1/2008 Male 11/19/2008 Physician Australia
Primary
Secondary
Unresponsive To Stimuli Required Intervention 10/13/2008 74 Female 154 lb 10/14/2008 Pharmacist United States
Primary
Secondary
Concomitant
Feeling Cold 9/10/2008 50 Female 11/14/2008 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection 12/6/2006 Female 134 lb 11/26/2008 Physician United States
Primary
Concomitant
Respiratory Failure Life Threatening 5/26/2008 Male 210 lb 1/5/2009 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 5/12/2007 Male 210 lb 1/8/2009 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 1/18/2009 65 Male 223 lb 2/9/2009 Physician United Kingdom
Primary
Concomitant
Sepsis Other Serious 5/12/2007 Male 210 lb 2/9/2009 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/2/2008 63 Female 2/5/2009 Physician Spain
Primary
Secondary
Concomitant
Urinary Tract Infection Pseudomonal Other Serious 1/1/1991 45 Female 270 lb 2/12/2009 United States
Primary
Concomitant
Sepsis Other Serious 5/12/2007 Male 210 lb 2/27/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2009 64 Female 3/3/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 1/1/1996 45 Male 4/2/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 8/12/2003 60 Male 216 lb 4/3/2009 United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 3/27/2009 60 Male 4/17/2009 Consumer United States
Primary
Secondary
Concomitant
Body Temperature Increased Hospitalization 4/18/2009 58 Male 157 lb 4/24/2009 Physician United States
Primary
Concomitant
Lethargy Required Intervention 2/18/2009 79 Male 217 lb 2/18/2009 Pharmacist United States
Primary
Secondary
Concomitant
Movement Disorder Death 1/29/2009 Male 150 lb 5/4/2009 Physician Brazil
Primary
Concomitant
Platelet Count Decreased Life Threatening 3/27/2009 60 Male 5/6/2009 Consumer United States
Primary
Secondary
Concomitant
Body Temperature Increased Hospitalization 4/18/2009 58 Male 157 lb 4/24/2009 Physician United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 42 Male 240 lb 5/20/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/19/2003 38 Male 220 lb 5/20/2009 United States
Primary
Concomitant
Upper Airway Obstruction Death 12/16/2008 82 Male 6/30/2009 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 4/1/2009 Male 213 lb 7/8/2009 Physician United States
Primary
Concomitant
Renal Dysplasia Congenital Anomaly 10/11/2004 Female 8 lb 7/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/13/2002 42 Male 213 lb 7/15/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 59 Female 155 lb 7/16/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/11/2005 58 Female 171 lb 7/21/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 41 Male 332 lb 7/30/2009 United States
Primary
Concomitant
Rash 6/29/2009 Male 175 lb 8/23/2009 United States
Primary
Concomitant
Upper Airway Obstruction Death 12/16/2008 82 Male 8/26/2009 Pharmacist United Kingdom
Primary
Concomitant
Retinal Artery Occlusion Disability 6/8/2009 Male 182 lb 9/2/2009 Physician Canada
Primary
Concomitant
Haematochezia Hospitalization 8/18/2009 83 Female 9/4/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
Haematochezia Hospitalization 8/18/2009 83 Female 9/16/2009 Other Health Professional United States
Primary
Concomitant
Road Traffic Accident Hospitalization 2/23/2001 59 Male 190 lb 9/23/2009 Other Health Professional United States
Primary
Concomitant
Haemorrhage Urinary Tract Hospitalization 10/13/2009 Male 209 lb 10/26/2009 United States
Primary
Concomitant
Sepsis Other Serious 1/1/2007 49 Male 10/29/2009 Lawyer United States
Primary
Secondary
Concomitant
Vascular Calcification Hospitalization 79 Female 10/26/2009 Lawyer United States
Primary
Concomitant
Renal Failure Hospitalization 10/13/2009 Male 209 lb 11/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 79 Female 11/18/2009 United States
Primary
Concomitant
Wound Infection Other Serious 7/22/2009 Male 224 lb 12/3/2009 Consumer United States
Primary
Concomitant
Apparent Death Life Threatening 69 Female 12/3/2009 Consumer
Primary
Secondary
Concomitant
Urinary Tract Infection 12/6/2006 Female 134 lb 12/1/2009 Physician United States
Primary
Concomitant
Sepsis Other Serious 5/12/2007 Male 210 lb 12/1/2009 Physician United States
Primary
Concomitant
Superficial Injury Of Eye 10/1/2009 Male 154 lb 12/7/2009 Consumer
Primary
Concomitant
Renal Failure Other Serious 2/13/2007 61 Male 214 lb 12/9/2009 Lawyer United States
Primary
Secondary
Concomitant
Ill-defined Disorder Other Serious 69 Female 12/22/2009 Consumer United States
Primary
Concomitant
Therapy Naive Hospitalization 79 Female 120 lb 1/19/2010 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 56 Female 1/21/2010 United States
Primary
Concomitant
Sepsis Other Serious 1/1/2007 49 Male 2/1/2010 Consumer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 2/4/2010 Consumer Canada
Primary
Secondary
Concomitant
Wound Infection Other Serious 7/22/2009 Male 224 lb 2/5/2010 Consumer United States
Primary
Concomitant
Sepsis Other Serious 5/12/2007 Male 210 lb 2/1/2010 Physician United States
Primary
Concomitant
Skin Discolouration Other Serious 6/23/2009 Male 300 lb 2/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Burning Sensation 2/5/2010 Female 187 lb 2/16/2010 United States
Primary
Concomitant
Headache 64 Female 2/23/2010 Physician United States
Primary
Concomitant

Drug Data