Metformin Hcl combined with Metoprolol Succinate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Mastitis Hospitalization 3/9/2006 55 Female 176 lb 6/27/2006 Physician Germany
Primary
Concomitant
Blood Glucose Increased Required Intervention 11/28/2005 60 Female 192 lb 1/19/2006 Physician United States
Primary
Secondary
Concomitant
Mastitis Hospitalization 3/9/2006 55 Female 187 lb 7/14/2006 Physician Germany
Primary
Concomitant
Thrombosis Hospitalization 1/1/2006 Male 210 lb 8/24/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 9/11/2006 Brazil
Primary
Secondary
Concomitant
Vasculitic Rash Hospitalization 5/18/2006 Male 9/21/2006 Pharmacist United States
Primary
Concomitant
Vasculitic Rash Hospitalization 5/18/2006 Male 9/21/2006 Pharmacist United States
Primary
Concomitant
Vasculitic Rash Hospitalization 5/18/2006 Male 9/21/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 10/11/2006 Brazil
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 70 Male 10/20/2006 Brazil
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 2/22/2006 73 Female 192 lb 11/6/2006
Primary
Concomitant
Splenomegaly Other Serious 2/27/2006 73 Male 218 lb 11/3/2006 Other Health Professional Germany
Primary
Concomitant
Intentional Overdose Death 58 NotSpecified 11/14/2006 Physician United States
Primary
Secondary
Vomiting 5/29/2006 48 Female 249 lb 11/30/2006 Consumer United States
Primary
Concomitant
Speech Disorder Other Serious 7/21/2006 86 Male 164 lb 7/26/2006 Pharmacist United States
Primary
Concomitant
Urticaria 5/18/2006 57 Male 365 lb 5/18/2006 United States
Primary
Concomitant
Completed Suicide Death 58 11/28/2006 Physician United States
Primary
Secondary
Expired Drug Administered 72 Male 190 lb 12/1/2006 Consumer United States
Primary
Concomitant
Vertigo Hospitalization 1/26/2006 67 Female 130 lb 12/5/2006 Physician Sweden
Primary
Concomitant
Circulatory Collapse Death 12/14/2006 Male 173 lb 12/22/2006 Other Health Professional Canada
Primary
Concomitant
Torsade De Pointes Life Threatening 9/9/2006 60 Male 275 lb 11/6/2006 Pharmacist United States
Primary
Concomitant
Visual Disturbance Other Serious 12/19/2006 Male 245 lb 12/28/2006 Consumer United States
Primary
Concomitant
Psychotic Disorder Hospitalization 12/16/2006 63 Male 183 lb 12/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 12/19/2006 55 Male 197 lb 12/21/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/10/2006 50 Female 12/26/2006 Physician Hong Kong
Primary
Secondary
Concomitant
High Density Lipoprotein Decreased Other Serious 1/1/2005 72 Male 174 lb 1/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/25/2006 69 Male 10/6/2006 United States
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 1/28/2006 83 Male 192 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2006 Female 1/9/2007 Consumer United States
Primary
Concomitant
Post Procedural Complication Hospitalization 1/1/2006 62 Female 200 lb 1/9/2007 Consumer United States
Primary
Concomitant
Syncope Life Threatening 9/30/2006 73 Male 1/10/2007
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 1/1/2006 53 Female 150 lb 1/15/2007 Consumer United States
Primary
Concomitant
Myalgia Other Serious 10/3/2006 Male 1/17/2007 Pharmacist United States
Primary
Concomitant
Dyspnoea 73 Female 1/23/2007 Consumer United States
Primary
Concomitant
Decreased Appetite 1/1/2006 Male 10/16/2006 Consumer United States
Primary
Concomitant
Paradoxical Drug Reaction Hospitalization 1/24/2007 78 Female 112 lb 1/26/2007 Pharmacist United States
Primary
Concomitant
Shock Other Serious 9/15/2006 Male 172 lb 2/6/2007 Physician Germany
Primary
Concomitant
Hyperhidrosis Other Serious 77 Male 222 lb 8/17/2006 United States
Primary
Concomitant
Confusional State Other Serious Male 2/23/2006 Other Health Professional United States
Primary
Concomitant
Epistaxis Hospitalization 2/7/2007 74 Male 138 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Nausea 8/3/2006 Female 10/16/2006 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 74 Male 2/26/2007 Consumer France
Primary
Concomitant
Nausea 58 Female 170 lb 10/16/2006 Consumer United States
Primary
Concomitant
Rash 12/26/2006 62 Male 2/28/2007 Consumer United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 1/1/2005 52 Female 150 lb 3/1/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 11/23/2006 54 Female 301 lb 3/2/2007 Consumer United States
Primary
Concomitant
Hypertension Life Threatening 12/6/2006 3/5/2007 Physician Canada
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 1/1/2005 52 Female 150 lb 3/7/2007 Physician United States
Primary
Concomitant
Duodenal Ulcer Hospitalization 1/23/2007 67 Female 148 lb 1/31/2007 Pharmacist United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 10/3/2006 60 Female 247 lb 3/20/2007 Physician Lithuania
Primary
Concomitant
Pain Other Serious 1/20/2007 Female 297 lb 3/21/2007 Consumer Canada
Primary
Concomitant
Stomach Discomfort 2/21/2007 77 Female 3/8/2007 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 2/1/2006 67 Female 8/17/2006 Physician United States
Primary
Concomitant
Mental Status Changes Hospitalization 2/21/2007 77 Male 211 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Shock Hospitalization 2/21/2007 Male 3/28/2007 Physician United States
Primary
Secondary
Concomitant
Lethargy Hospitalization 1/30/2007 74 Male 227 lb 3/29/2007 Physician United States
Primary
Secondary
Concomitant
Urticaria Other Serious 1/20/2007 63 Male 337 lb 1/25/2007 Pharmacist United States
Primary
Concomitant
Shock Death 2/21/2007 77 Male 211 lb 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Asthma Hospitalization 1/1/2007 Male 317 lb 4/3/2007 Pharmacist Germany
Primary
Concomitant
Diarrhoea Hospitalization 1/30/2007 Male 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Musculoskeletal Pain Other Serious 1/1/2006 Female 220 lb 4/4/2007 Consumer Netherlands
Primary
Concomitant
Septic Shock Death 2/21/2007 Male 4/5/2007 Physician United States
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 59 Male 4/6/2007 Pharmacist Ireland
Primary
Concomitant
Fall Hospitalization 3/15/2007 75 Female 4/3/2007 Consumer Canada
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 4/6/2007 57 Male 400 lb 4/6/2007 Consumer United States
Primary
Secondary
Concomitant
Spinal Column Stenosis 10/18/2006 77 Female 195 lb 1/12/2007 Consumer United States
Primary
Concomitant
Weight Increased 10/1/2006 71 Male 256 lb 1/12/2007 Consumer United States
Primary
Concomitant
Death Death 11/2/2006 Female 195 lb 4/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/27/2007 Male 227 lb 4/19/2007 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/30/2007 74 Male 227 lb 4/20/2007 Physician United States
Primary
Secondary
Concomitant
Sensation Of Foreign Body 11/11/2006 69 Female 181 lb 1/12/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/30/2007 Male 4/25/2007 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite 1/1/2006 65 Female 200 lb 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
Tachyarrhythmia Death 11/2/2006 Female 195 lb 4/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Infection Hospitalization 1/27/2007 Male 227 lb 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Toothache 75 Male 185 lb 4/30/2007 United States
Primary
Concomitant
Rash Hospitalization 9/1/2006 Female 186 lb 5/1/2007 Physician United States
Primary
Concomitant
Radius Fracture Other Serious 3/24/2007 57 Female 212 lb 5/8/2007 Physician Germany
Primary
Concomitant
Loss Of Consciousness Hospitalization 76 Female 5/1/2007
Primary
Concomitant
Foot Fracture Other Serious 62 Male 5/11/2007 Physician Germany
Primary
Concomitant
Multi-organ Failure Death 11/2/2006 Female 195 lb 5/15/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Foot Fracture Other Serious 3/1/2006 62 Male 5/21/2007 Physician Germany
Primary
Concomitant
Electrocardiogram Abnormal 73 Female 5/21/2007 United States
Primary
Concomitant
Cardiac Failure Other Serious 59 Male 5/25/2007 Ireland
Primary
Concomitant
Secondary Adrenocortical Insufficiency Hospitalization 11/7/2006 41 Male 179 lb 5/30/2007 Physician Netherlands
Primary
Concomitant
Vomiting Hospitalization 11/2/2006 68 Male 195 lb 2/14/2007 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization Male 6/4/2007 Physician Canada
Primary
Concomitant
Pyrexia Hospitalization Male 6/5/2007 Physician Canada
Primary
Concomitant
Vomiting 12/1/2006 67 Male 220 lb 4/23/2007 Physician United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 9/11/2006 48 Female 162 lb 6/1/2007 Consumer United States
Primary
Concomitant
Drug Withdrawal Syndrome Required Intervention 5/7/2006 52 Female 220 lb 4/13/2007 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased 3/30/2007 81 Female 5/17/2007 United States
Primary
Concomitant
Upper Respiratory Tract Infection 1/9/2007 56 Female 180 lb 5/17/2007 Physician United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 5/23/2007 64 Male 6/7/2007 Pharmacist United States
Primary
Concomitant
Hypotension 1/24/2007 84 Female 5/17/2007 United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 6/1/2002 63 Male 269 lb 6/12/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 59 Female 6/12/2007 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 6/2/2007 69 Female 120 lb 6/10/2007 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Unexpected Hospitalization 12/10/2006 53 Female 6/14/2007 Consumer United States
Primary
Concomitant
Nausea 2/18/2007 50 Male 270 lb 4/10/2007 Consumer United States
Primary
Concomitant
Drug Interaction Other Serious 59 Male 6/19/2007 Ireland
Primary
Concomitant
Interacting
Nausea Life Threatening 6/3/2007 Female 154 lb 6/21/2007 Other Health Professional United States
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 8/29/2006 56 Female 6/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Postoperative Wound Infection Hospitalization 205 lb 6/25/2007 Consumer Canada
Primary
Concomitant
Hyperglycaemia Other Serious 2/7/2007 65 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 59 Male 6/29/2007 Physician Canada
Primary
Concomitant
Hypersomnia Other Serious 1/13/2007 77 Female 260 lb 7/2/2007 Physician Germany
Primary
Concomitant
Swelling Face Other Serious 4/1/2007 64 Female 328 lb 7/3/2007 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Female 220 lb 7/13/2007 Physician United States
Primary
Secondary
Rash Required Intervention 7/9/2007 47 Female 188 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 9/11/2006 48 Female 162 lb 7/25/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/15/2007 Female 8/2/2007 Pharmacist Germany
Primary
Secondary
Concomitant
Pseudomonas Infection Other Serious 6/17/2007 65 Male 229 lb 8/3/2007 Physician United States
Primary
Secondary
Concomitant
Rectal Cancer Metastatic Death 3/13/2005 78 Male 7/31/2007 Canada
Primary
Concomitant
Syncope Hospitalization 5/25/2006 71 Female 8/3/2007 Pharmacist United States
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2007 Male 240 lb 8/10/2007 Physician United States
Primary
Concomitant
Amnesia 4/6/2007 65 Male 280 lb 7/10/2007 Consumer United States
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 6/17/2007 65 Male 229 lb 8/10/2007 Physician United States
Primary
Secondary
Concomitant
Hepatitis Acute Hospitalization 6/21/2007 44 Male 8/14/2007 Physician Australia
Primary
Concomitant
Nausea 5/1/2007 8/10/2007 Consumer United States
Primary
Concomitant
Drug Interaction Other Serious 66 Male 8/16/2007 Sweden
Primary
Concomitant
Interacting
Methaemoglobinaemia Hospitalization 57 Male 8/20/2007
Primary
Secondary
Concomitant
Hepatitis Acute Hospitalization 6/21/2007 44 Male 8/20/2007 Physician Australia
Primary
Concomitant
Hypotension Other Serious 4/5/2007 81 Female 133 lb 7/25/2007 United States
Primary
Concomitant
Orthopnoea Other Serious 4/30/2004 55 Male 226 lb 9/5/2007 Physician Canada
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 7/1/2007 86 Female 9/5/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Oedema Peripheral 1/1/2007 Male 140 lb 8/21/2007 United States
Primary
Concomitant
Hallucination, Visual Other Serious 12/12/2006 51 Male 279 lb 9/6/2007 Consumer United States
Primary
Concomitant
Restless Legs Syndrome 11/1/2006 68 Male 9/6/2007 Consumer United States
Primary
Concomitant
Speech Disorder Hospitalization 5/14/2007 9/10/2007 Consumer Germany
Primary
Concomitant
Pancreatitis Chronic Other Serious 1/5/2005 Male 128 lb 9/12/2007 Physician Mexico
Primary
Concomitant
Muscular Weakness Hospitalization 75 Male 280 lb 9/12/2007 Physician United States
Primary
Concomitant
Coronary Artery Disease Other Serious 9/12/2007 Female 287 lb 9/12/2007 Physician United States
Primary
Concomitant
Hyperkalaemia Hospitalization 9/6/2007 70 Female 159 lb 9/19/2007 Physician Germany
Primary
Secondary
Concomitant
Pain In Extremity Other Serious Male 9/19/2007 Consumer Canada
Primary
Concomitant
Weight Increased Hospitalization 10/1/2000 Male 10/2/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 4/1/2007 Male 250 lb 10/3/2007 Physician United States
Primary
Concomitant
Drug Effect Decreased 8/2/2007 Male 11/12/2007 Pharmacist United States
Primary
Concomitant
Medication Error Death 9/5/2006 78 Female 11/26/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased 2/1/2007 64 Male 230 lb 11/16/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/4/2007 Female 12/14/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection 9/19/2007 Female 160 lb 12/14/2007 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 189 lb 12/19/2007 Physician United States
Primary
Concomitant
Prostatic Specific Antigen Increased 71 Male 12/20/2007 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 7/10/2007 66 Male 12/21/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Colorectal Cancer Hospitalization 2/20/2006 64 Female 152 lb 12/26/2007 Germany
Primary
Concomitant
Pulmonary Oedema Hospitalization 7/10/2007 66 Male 1/2/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/4/2007 Female 1/11/2008 Physician United States
Primary
Concomitant
Colorectal Cancer Hospitalization 2/20/2006 64 Female 152 lb 1/14/2008 Germany
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 9/15/2007 60 Female 1/16/2008 Physician Switzerland
Primary
Concomitant

Drug Data