Metformin Hcl combined with Metolazone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Hospitalization 3/1/2005 85 Female 1/26/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 50 Male 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting 3/17/2006 71 Female 193 lb 7/19/2006 Consumer United States
Primary
Concomitant
Nodal Arrhythmia Life Threatening 4/26/2006 Female 205 lb 10/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Palpitations 37 Female 224 lb 1/23/2007 Consumer United States
Primary
Concomitant
Weight Decreased 8/1/2006 66 Male 275 lb 1/12/2007 Consumer United States
Primary
Concomitant
Weight Decreased 7/10/2006 66 Male 275 lb 4/10/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/20/2007 Male 260 lb 8/1/2007 Pharmacist United States
Primary
Concomitant
Weight Increased 9/1/2006 39 Male 11/14/2007 Consumer United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 11/1/2007 Male 12/12/2007 Consumer United States
Primary
Concomitant
Hypothyroidism Other Serious 4/1/2008 Male 228 lb 5/19/2008 Consumer United States
Primary
Concomitant
Respiratory Distress Hospitalization 4/29/2008 Male 260 lb 5/27/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/10/2007 60 Male 149 lb 6/23/2008 United States
Primary
Concomitant
Weight Decreased Required Intervention 10/15/2007 60 Male 153 lb 7/24/2008 United States
Primary
Concomitant
Tremor Hospitalization 7/11/2008 Female 170 lb 9/12/2008 Consumer United States
Primary
Concomitant
Tremor Hospitalization 7/11/2008 Female 170 lb 11/10/2008 Consumer United States
Primary
Concomitant
Blood Glucose Increased 10/20/2008 Female 11/26/2008 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 59 Female 11/26/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 59 Female 216 lb 1/12/2009
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 4/1/2008 56 Female 1/15/2009 Consumer United States
Primary
Concomitant
Blood Glucose Increased 10/14/2008 75 Male 234 lb 2/3/2009 Physician United States
Primary
Concomitant
Hypertension Hospitalization 6/2/2003 44 Male 401 lb 4/22/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 9/1/2006 Male 295 lb 4/29/2009 Physician United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 11/1/2007 71 Female 142 lb 6/19/2009 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 5/19/2009 60 Male 6/26/2009 Physician United States
Primary
Concomitant
Nausea 90 Male 7/14/2009 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 64 Male 250 lb 7/23/2009 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious Male 7/23/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 47 Male 8/3/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 47 Male 8/11/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 4/23/2007 54 Female 258 lb 8/12/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 8/12/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 4/29/2008 Male 260 lb 8/27/2009 Physician United States
Primary
Concomitant
Unevaluable Event Death 71 Male 8/23/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/1/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 9/1/2009 Lawyer United States
Primary
Concomitant
Thyroxine Free Increased Other Serious 4/23/2007 54 Female 258 lb 9/2/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 47 Male 9/2/2009 United States
Primary
Concomitant
Metabolic Acidosis Death 7/28/2009 55 Male 348 lb 9/9/2009 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/4/2009 United States
Primary
Concomitant
Surgery Hospitalization 47 Male 9/3/2009 United States
Primary
Concomitant
Weight Increased Other Serious 4/23/2007 54 Female 258 lb 9/3/2009 United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 9/10/2009 United States
Primary
Concomitant
Surgery Death Female 9/11/2009 United States
Primary
Concomitant
Syncope Hospitalization 58 Male 9/15/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 9/15/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/16/2009 Lawyer United States
Primary
Concomitant
Pain In Extremity Hospitalization 47 Male 10/27/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 10/26/2009 United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 10/26/2009 United States
Primary
Concomitant
Muscular Weakness Other Serious 9/15/2009 78 Female 184 lb 11/14/2009 Other Health Professional United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 11/16/2009 United States
Primary
Concomitant
X-ray Limb Abnormal Other Serious 72 Male 11/16/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 11/18/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 4/23/2007 54 Female 258 lb 11/18/2009 United States
Primary
Concomitant
Dizziness 8/29/2009 46 Female 1/8/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 72 Male 201 lb 1/11/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 72 Male 201 lb 1/20/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 2/4/2010 Consumer Canada
Primary
Secondary
Concomitant
Presyncope Hospitalization Female 98 lb 2/5/2010 Consumer United States
Primary
Concomitant
Skin Discolouration Other Serious 6/23/2009 Male 300 lb 2/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 2/25/2009 Female 3/12/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 3/31/2010 Lawyer United States
Primary
Concomitant
Urinary Retention Other Serious 60 Male 236 lb 4/22/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 60 Female 6/21/2010
Primary
Secondary
Rash Other Serious 2/26/2008 87 Male 151 lb 6/23/2010 Other Health Professional United States
Primary
Concomitant
Torsade De Pointes Other Serious 64 Female 6/30/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 64 Female 6/30/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 64 Female 6/30/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 7/1/2010 Consumer Canada
Primary
Secondary
Concomitant
Drug Intolerance Hospitalization Female 236 lb 7/2/2010 Consumer United States
Primary
Concomitant
Splenomegaly Hospitalization 1/1/2010 67 Female 294 lb 7/13/2010 Physician United States
Primary
Concomitant
Fluid Overload Hospitalization Female 236 lb 7/15/2010 Physician United States
Primary
Concomitant
Renal Disorder Other Serious 11/1/2006 56 Male 250 lb 7/29/2010 Physician United States
Primary
Concomitant
Erectile Dysfunction Other Serious 1/2/2008 59 Male 220 lb 7/31/2010 Consumer United States
Primary
Concomitant
Vision Blurred Required Intervention 60 Female 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 4/30/2010 Male 8/4/2010 Physician Switzerland
Primary
Concomitant
Vision Blurred Required Intervention 60 Female 8/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 77 Male 201 lb 8/27/2010 United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 8/26/2010 69 Male 11/19/2010 Physician Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 8/26/2010 69 Male 12/6/2010 Physician Canada
Primary
Secondary
Concomitant
Pneumonia Hospitalization 41 Female 201 lb 1/28/2011 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 75 Female 179 lb 6/2/2011 Physician United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 75 Female 179 lb 6/1/2011 Physician United States
Primary
Secondary
Concomitant
Interacting
Weight Decreased Other Serious 1/1/2011 62 Female 326 lb 6/3/2011 United States
Primary
Concomitant
Death Death 51 Male 6/22/2011 Pharmacist United States
Primary
Concomitant
Anaemia Other Serious 7/1/2006 55 Male 351 lb 6/30/2011 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious Female 291 lb 7/21/2011 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 4/1/2007 66 Male 351 lb 8/1/2011 Lawyer United States
Primary
Concomitant
Nausea Hospitalization 75 Female 179 lb 8/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 7/12/2011 63 Male 251 lb 8/2/2011 Pharmacist United States
Primary
Concomitant
Pancreatitis Relapsing Other Serious 11/1/2006 56 Male 250 lb 8/3/2011 Consumer United States
Primary
Concomitant
Pulmonary Fibrosis Death Female 198 lb 8/1/2011 Physician United States
Primary
Concomitant
Skin Hypopigmentation Other Serious 48 Female 291 lb 8/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 3/1/2011 75 Female 396 lb 8/17/2011 Physician United States
Primary
Secondary
Concomitant
Hilar Lymphadenopathy Other Serious Male 9/21/2011 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 48 Female 291 lb 10/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Leukopenia Hospitalization Male 10/25/2011 Physician United States
Primary
Concomitant
Hepatic Steatosis Hospitalization Female 11/1/2011 Pharmacist United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 10/15/2011 11/3/2011 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization Female 11/7/2011 Lawyer United States
Primary
Secondary
Concomitant
Hepatic Steatosis Hospitalization Female 11/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 10/19/2011 63 Male 11/22/2011 Physician Canada
Primary
Secondary
Haematoma Other Serious Female 11/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Specific Antibody Present Other Serious 9/26/2011 53 Male 11/23/2011 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 10/19/2011 63 Male 12/8/2011 Physician Canada
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization Female 12/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 9/1/2011 62 Male 300 lb 12/16/2011 Consumer United States
Primary
Concomitant
Nicotine Dependence Other Serious 1/1/2006 48 Female 220 lb 12/8/2011 Lawyer United States
Primary
Concomitant
Dyspnoea Hospitalization 10/19/2011 63 Male 12/20/2011 Physician Canada
Primary
Secondary
Concomitant
Muscle Spasms Other Serious Female 12/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 62 Female 12/21/2011 Physician United States
Primary
Secondary
Wrong Technique In Drug Usage Process Hospitalization 9/1/2011 62 Male 300 lb 1/5/2012 Consumer United States
Primary
Concomitant
Toxicity To Various Agents Death 62 Female 1/9/2012 Physician United States
Primary
Secondary
Pancreatitis Other Serious Female 268 lb 11/17/2011 Lawyer United States
Primary
Concomitant
Renal Disorder Other Serious 11/1/2006 56 Male 250 lb 11/17/2011 Lawyer United States
Primary
Concomitant
Tenosynovitis Stenosans Other Serious Female 1/9/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 10/19/2011 63 Male 1/10/2012 Physician Canada
Primary
Secondary
Concomitant
Hypermetabolism Other Serious Female 1/11/2012 Lawyer United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 62 Female 1/11/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 62 Female 1/12/2012 Physician United States
Primary
Secondary
Death Death 1/1/2010 62 Female 1/13/2012 Physician United States
Primary
Secondary
Cough Other Serious 1/6/2012 64 Male 1/13/2012 United States
Primary
Concomitant
Toxicity To Various Agents Death 62 Female 1/11/2012 Physician United States
Primary
Secondary
Heart Rate Increased Hospitalization Female 1/17/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization Male 1/17/2012 Physician United States
Primary
Concomitant
Poisoning Death 1/1/2010 62 Female 1/11/2012 Physician United States
Primary
Secondary
Arteriosclerosis Coronary Artery Hospitalization Male 1/18/2012 Physician United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 62 Female 1/19/2012 United States
Primary
Concomitant
Renal Impairment 1/1/2012 68 Male 1/20/2012 Consumer United States
Primary
Concomitant
Toxicity To Various Agents Death 62 Female 1/23/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 62 Female 1/13/2012 Physician United States
Primary
Secondary
Death Death 62 Female 1/24/2012 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Death 1/1/2010 62 Female 1/13/2012 Physician United States
Primary
Secondary
Death Death 62 Female 1/17/2012 Other Health Professional Denmark
Primary
Secondary
Hydronephrosis Life Threatening 1/1/2006 55 Female 280 lb 1/20/2012 Consumer United States
Primary
Concomitant
Pruritus 9/1/2011 61 Female 240 lb 1/28/2012 Consumer United States
Primary
Concomitant
Flushing 1/1/2012 Male 1/31/2012 Consumer United States
Primary
Concomitant
Toxicity To Various Agents Death 1/1/2010 62 Female 1/13/2012 Physician United States
Primary
Secondary
Dry Mouth Other Serious 9/26/2011 53 Male 2/1/2012 Other Health Professional United States
Primary
Concomitant
Obesity Other Serious Male 1/30/2012 Physician United States
Primary
Concomitant
Tenosynovitis Stenosans Other Serious Female 2/3/2012 Lawyer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious Female 2/8/2012 Consumer United States
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization Female 2/10/2012 Consumer United States
Primary
Secondary
Concomitant
Limb Asymmetry Other Serious Male 216 lb 2/6/2012 Lawyer United States
Primary
Concomitant
Cough Other Serious 1/6/2012 64 Male 2/20/2012 Physician United States
Primary
Concomitant
Skin Ulcer Other Serious 48 Female 291 lb 2/20/2012 Consumer United States
Primary
Secondary
Concomitant
Intracardiac Thrombus Hospitalization 12/24/2007 46 Male 271 lb 2/23/2012 Other Health Professional United States
Primary
Concomitant
Death Death 62 Female 3/2/2012 Other Health Professional United States
Primary
Secondary
Hypoglycaemia Other Serious 12/11/2011 50 Female 285 lb 2/23/2012 Physician United States
Primary
Concomitant

Drug Data