Mesna combined with Vincristine Sulfate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Rate Increased Hospitalization 7/21/2005 Female 31 lb 2/2/2006 United States
Primary
Secondary
Urinary Tract Infection Other Serious 3/6/2006 Female 111 lb 3/15/2006 United States
Primary
Secondary
Performance Status Decreased Other Serious 3/13/2006 Male 216 lb 3/29/2006 United States
Primary
Secondary
Vomiting Hospitalization 4/11/2006 Female 214 lb 4/28/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 3/20/2006 70 Female 117 lb 5/11/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 3/4/2006 Male 311 lb 8/11/2006 United States
Primary
Secondary
White Blood Cell Count Increased Hospitalization 8/16/2006 Female 108 lb 9/8/2006 United States
Primary
Secondary
White Blood Cell Count Increased Hospitalization 8/16/2006 Female 108 lb 9/27/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 9/4/2006 12 Male 12/18/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/12/2006 50 Male 166 lb 2/9/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/12/2006 51 Male 166 lb 2/20/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/19/2007 Male 198 lb 5/8/2007 United States
Primary
Secondary
Tachycardia Hospitalization 6/3/2007 Male 188 lb 6/8/2007 United States
Primary
Secondary
Ventricular Extrasystoles Death 4/18/2007 69 Female 6/22/2007 France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/18/2007 Female 141 lb 7/20/2007 United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Death 4/17/2007 53 Female 7/27/2007 United States
Primary
Secondary
Tremor Life Threatening 7/5/2007 36 Female 119 lb 8/2/2007 Other Health Professional Portugal
Primary
Concomitant
Vomiting Hospitalization 7/25/2007 Male 187 lb 7/30/2007 United States
Primary
Secondary
Premature Baby Other Serious Male 9/14/2007 Consumer United States
Primary
Secondary
Tumour Lysis Syndrome Hospitalization 9/18/2007 Male 492 lb 10/2/2007 United States
Primary
Secondary
Wound Secretion Hospitalization 9/27/2007 Male 467 lb 10/8/2007 United States
Primary
Secondary
Soft Tissue Necrosis Hospitalization 10/27/2007 Female 99 lb 11/2/2007 United States
Primary
Secondary
Concomitant
Vulval Disorder Hospitalization 10/27/2007 Female 99 lb 11/15/2007 Canada
Primary
Secondary
Encephalopathy Other Serious 70 Male 11/21/2007 Other Health Professional Italy
Primary
Secondary
Vomiting Other Serious 11/11/2007 Male 289 lb 12/4/2007 United States
Primary
Secondary
Pseudomonas Infection Hospitalization 12/12/2007 Female 166 lb 1/2/2008 United States
Primary
Secondary
Tachycardia Hospitalization 12/21/2007 Male 289 lb 1/7/2008 United States
Primary
Secondary
Vomiting Other Serious 12/17/2007 69 Male 1/23/2008 Consumer United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 1/21/2008 Female 21 lb 1/23/2008 United States
Primary
Secondary
Concomitant
Venous Pressure Jugular Increased Hospitalization 1/21/2008 Female 21 lb 1/28/2008 Canada
Primary
Secondary
Concomitant
Venous Pressure Jugular Increased Hospitalization 1/21/2008 Female 21 lb 2/8/2008 United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 2/19/2008 Male 187 lb 2/28/2008 United States
Primary
Secondary
Weight Decreased Hospitalization 3/30/2008 Male 203 lb 4/7/2008 United States
Primary
Secondary
Weight Decreased Hospitalization 3/30/2008 Male 203 lb 4/10/2008 United States
Primary
Secondary
Lower Respiratory Tract Infection Fungal Hospitalization 5/6/2008 Female 17 lb 5/8/2008 United States
Primary
Secondary
Hypocalcaemia Hospitalization 3/4/2008 Male 183 lb 5/8/2008 United States
Primary
Secondary
Pulmonary Mycosis Hospitalization 5/6/2008 Female 17 lb 5/12/2008 United States
Primary
Secondary
Renal Failure Other Serious 14 Male 6/12/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/30/2008 Male 203 lb 6/9/2008 United States
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 6/13/2008 Female 141 lb 6/19/2008 United States
Primary
Secondary
Stomatitis Hospitalization 6/13/2008 Female 141 lb 7/7/2008 United States
Primary
Secondary
Neuropathy Peripheral Other Serious 1/1/2007 37 Male 7/29/2008 India
Primary
Secondary
Concomitant
Malabsorption 7/28/2008 Male 125 lb 7/28/2008 United States
Primary
Secondary
Transient Ischaemic Attack Hospitalization 7/22/2008 9 Male 76 lb 8/8/2008 Physician United States
Primary
Secondary
Concomitant
Wound Infection Bacterial Hospitalization 5/27/2007 Female 141 lb 6/20/2007 United States
Primary
Secondary
Urine Leukocyte Esterase Positive Hospitalization 10/5/2008 Male 209 lb 10/9/2008 United States
Primary
Secondary
Death Death 67 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 66 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Urine Leukocyte Esterase Positive Hospitalization 11/23/2008 Male 209 lb 1/8/2009 United States
Primary
Secondary
Pharyngeal Oedema Hospitalization 12/27/2008 Male 183 lb 12/30/2008 United States
Primary
Secondary
Epilepsy Other Serious 12/23/2008 15 Female 2/3/2009 Pharmacist Norway
Primary
Secondary
Concomitant
Sepsis Hospitalization 11/15/2008 Male 192 lb 2/9/2009 United States
Primary
Secondary
Weight Decreased Hospitalization 10/6/2008 Male 192 lb 2/11/2009 United States
Primary
Secondary
Speech Disorder Other Serious 12/1/2008 33 Male 2/27/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Speech Disorder Other Serious 12/1/2008 33 Male 3/25/2009 Pharmacist Norway
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/5/2009 1 Female 15 lb 3/27/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2009 1 Female 15 lb 4/13/2009 Physician
Primary
Secondary
Concomitant
Convulsion Other Serious 6 Female 5/4/2009 Other Health Professional Italy
Primary
Secondary
Convulsion Other Serious 9 Male 5/4/2009 Other Health Professional Italy
Primary
Secondary
Somnolence Other Serious 5 Female 5/4/2009 Other Health Professional Italy
Primary
Secondary
Convulsion Life Threatening 6 Female 5/4/2009 Other Health Professional Italy
Primary
Secondary
Septic Shock Hospitalization 5/4/2009 Female 30 lb 5/5/2009 United States
Primary
Secondary
Septic Shock Hospitalization 5/4/2009 Female 30 lb 5/13/2009 United States
Primary
Secondary
Pyrexia Hospitalization 5/2/2009 Male 157 lb 5/19/2009 United States
Primary
Secondary
Septic Shock Hospitalization 5/4/2009 Female 30 lb 5/22/2009 United States
Primary
Secondary
Shock Hospitalization 5/4/2009 Female 30 lb 6/5/2009 United States
Primary
Secondary
Diffuse Large B-cell Lymphoma Other Serious 1/1/1998 67 Female 6/23/2009 Consumer Japan
Primary
Secondary
Streptococcal Sepsis Hospitalization 5/4/2009 Female 30 lb 6/17/2009 United States
Primary
Secondary
Diffuse Large B-cell Lymphoma Other Serious 1/1/1998 67 Female 6/26/2009 Other Health Professional Italy
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 6/12/2009 Male 163 lb 6/23/2009 United States
Primary
Secondary
Speech Disorder Other Serious 12/1/2008 33 Male 8/7/2009 Pharmacist Norway
Primary
Secondary
Concomitant
Spinal Cord Disorder Hospitalization 12/3/2009 Male 39 lb 12/11/2009 United States
Primary
Secondary
Spinal Cord Disorder Hospitalization 12/3/2009 Male 39 lb 12/22/2009 United States
Primary
Secondary
Nephrogenic Diabetes Insipidus Other Serious 64 Male 12/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/12/2010 8 Female 3/18/2010 Other Health Professional France
Primary
Secondary
Epilepsy Other Serious 12/23/2008 15 Female 4/8/2010 Pharmacist Norway
Primary
Secondary
Venoocclusive Liver Disease Other Serious 14 Male 5/19/2010 Other Health Professional Canada
Primary
Secondary
Venoocclusive Liver Disease Other Serious 14 Male 5/28/2010 Other Health Professional Canada
Primary
Secondary
Hemiparesis Other Serious 7/1/2008 13 Male 134 lb 8/26/2010 Other Health Professional Belgium
Primary
Secondary
Restlessness Other Serious 12/16/2008 33 Male 10/6/2010 Other Health Professional Norway
Primary
Secondary
Concomitant
Septic Shock Hospitalization 11/28/2010 12 Male 98 lb 12/2/2010 United States
Primary
Secondary
Malignant Melanoma 12/3/2010 66 Male 157 lb 12/15/2010 United States
Primary
Secondary
Herpes Zoster Other Serious 11/23/2010 65 Male 12/28/2010 Other Health Professional France
Primary
Secondary
Concomitant
Malignant Melanoma Of Sites Other Than Skin 12/3/2010 66 Male 157 lb 1/3/2011 United States
Primary
Secondary
Skin Necrosis Other Serious 11/23/2010 65 Male 1/20/2011 Other Health Professional France
Primary
Secondary
Concomitant
Colitis Ischaemic Other Serious 51 Male 2/18/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 11/23/2010 65 Male 2/18/2011 Other Health Professional France
Primary
Secondary
Concomitant
Fanconi Syndrome Other Serious 1 2/23/2011 Physician France
Primary
Secondary
Fanconi Syndrome Other Serious 2 2/23/2011 Other Health Professional France
Primary
Secondary
Fanconi Syndrome Other Serious 1 2/23/2011 Other Health Professional France
Primary
Secondary
Fanconi Syndrome Other Serious 2 2/23/2011 Physician France
Primary
Secondary
Burning Sensation Hospitalization Male 101 lb 3/3/2011 Other Health Professional Canada
Primary
Concomitant
Angioedema Hospitalization 8 Male 3/1/2011 Pharmacist United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 3/3/2011 4 Male 42 lb 3/3/2011 Physician United States
Primary
Secondary
Transaminases Increased Hospitalization 3/7/2011 Male 17 lb 3/8/2011 Australia
Primary
Secondary
Metastases To Pleura Hospitalization 3/7/2011 Male 17 lb 3/14/2011 Physician Australia
Primary
Secondary
Convulsion Other Serious 1/11/2010 22 Male 4/1/2011 Other Health Professional France
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 3/16/2011 50 Male 4/13/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Haemodynamic Instability Death 3/3/2011 4 Male 42 lb 4/1/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 55 Male 4/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Hospitalization 4/6/2011 5 Male 41 lb 4/11/2011 Other Health Professional United States
Primary
Secondary
Drug Interaction Life Threatening 3/16/2011 50 Male 4/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Burkitt's Lymphoma Death 55 Male 4/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Leukopenia Life Threatening 50 Male 4/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
No Therapeutic Response Life Threatening 50 Male 4/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Failure Death 5/5/2011 Physician United States
Primary
Secondary
Concomitant
Infection In An Immunocompromised Host Other Serious 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Death 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Marrow Failure Death 5/5/2011 Physician United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 5/5/2011 Physician United States
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 5/5/2011 Physician United States
Primary
Secondary
Concomitant
Bone Marrow Failure Death 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Infection In An Immunocompromised Host Death 5/5/2011 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 55 Male 5/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Hospitalization 3/23/2011 8 Male 66 lb 5/3/2011 United States
Primary
Secondary
Toxicity To Various Agents Other Serious 55 Male 5/23/2011 Consumer United Kingdom
Primary
Secondary
Multi-organ Failure Hospitalization 3/22/2011 8 Male 66 lb 5/16/2011 United States
Primary
Secondary
Back Pain Other Serious 7/9/2007 17 Female 5/26/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Burkitt's Lymphoma Other Serious 55 Male 5/27/2011 Consumer United Kingdom
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/2/2011 45 Female 6/3/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 5/4/2011 20 Male 183 lb 6/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Leukopenia Life Threatening 3/16/2011 50 Male 6/13/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Bone Pain Other Serious 7/9/2007 17 Female 6/16/2011 Lawyer Denmark
Primary
Secondary
Concomitant
Leukopenia Life Threatening 50 Male 6/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Unspecified Histology Aggressive Life Threatening 3/16/2011 50 Male 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/2/2011 45 Female 7/5/2011 Physician Spain
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 50 Male 7/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/1/2011 20 Male 7/13/2011 Physician United States
Primary
Secondary
Lymphocyte Count Decreased Hospitalization 7/12/2011 3 Female 34 lb 7/19/2011 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/1/2011 20 Male 7/28/2011 Physician United States
Primary
Secondary
Nausea Hospitalization 6/24/2011 11 Male 71 lb 8/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Other Serious 7/9/2007 17 Female 8/23/2011 Lawyer Denmark
Primary
Secondary
Concomitant
Swelling Face Hospitalization 9/15/2011 5 Male 40 lb 9/20/2011 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Hospitalization 3/9/2011 43 Male 202 lb 9/29/2011 United States
Primary
Secondary
Acute Myeloid Leukaemia Hospitalization 3/9/2011 43 Male 202 lb 9/29/2011 United States
Primary
Secondary
Fungaemia Hospitalization 7/15/2011 3 Female 24 lb 10/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 41 Female 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 26 Male 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 54 Female 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 51 Male 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 22 Female 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant

Drug Data