Meropenem combined with Vancomycin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 12/2/2004 65 9/12/2005 Pharmacist United States
Primary
Concomitant
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tracheostomy Life Threatening 7/10/2005 42 Female 1/23/2006 United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 23 Male 1/24/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Shock Hospitalization 1/19/2006 35 Female 1/20/2006 Physician Belgium
Primary
Concomitant
Respiratory Rate Increased Life Threatening 11/8/2005 70 Female 1/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Decreased Death 9/1/2005 67 Female 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Thrombotic Stroke Death 10/27/2005 45 Female 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Death 1/1/2005 72 Male 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/30/2005 Female 2/10/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/26/2004 Male 121 lb 2/17/2006 Physician United Kingdom
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 2/14/2006 0 Male 3/6/2006 Spain
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/1/2005 54 Female 1/20/2006 Physician United States
Primary
Concomitant
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/3/2005 63 Male 218 lb 3/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/10/2006 38 Male 176 lb 4/5/2006 Physician United States
Primary
Concomitant
Respiratory Rate Increased Life Threatening 11/20/2005 70 Female 4/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Death 3/26/2006 73 Male 4/24/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/30/2005 Female 84 lb 5/2/2006 Physician Japan
Primary
Secondary
Concomitant
Shock Other Serious 5/3/2006 0 Female 5/11/2006 Physician Spain
Primary
Concomitant
Rhabdomyolysis Life Threatening 4/14/2006 Male 5/24/2006 Physician Japan
Primary
Secondary
Concomitant
Systemic Mycosis Life Threatening 4/1/2006 49 Female 5/25/2006 Physician Austria
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2005 45 Female 165 lb 5/22/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 2/15/2006 Male 6/1/2006 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 4/14/2006 Male 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease Hospitalization 8/3/2003 28 Male 4/27/2006 Japan
Primary
Concomitant
Graft Versus Host Disease Hospitalization 3/14/2003 32 Male 4/27/2006 Japan
Primary
Concomitant
General Physical Health Deterioration Death 8/1/2004 13 Male 99 lb 6/6/2006 Pharmacist United States
Primary
Concomitant
Colitis Pseudomembranous Death 5 Female 6/15/2006 Physician United States
Primary
Secondary
Rhabdomyolysis Life Threatening 4/14/2006 50 Male 6/26/2006 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 4/29/2006 1 Female 6/21/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 5/25/2006 60 Male 198 lb 6/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tracheal Haemorrhage Hospitalization 5/31/2006 69 Male 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization 9/2/2004 75 Male 7/6/2006 Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 5/8/2006 69 Male 7/7/2006 Other Health Professional Japan
Primary
Concomitant
Hypomagnesaemia Life Threatening Male 7/17/2006 Physician United Kingdom
Primary
Concomitant
Swelling Face Other Serious 8/9/2004 51 Female 8/8/2006 Consumer Australia
Primary
Secondary
Transaminases Increased Hospitalization 7/3/2003 35 Female 8/24/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Septic Shock Death 36 Female 8/17/2006 Other Health Professional Australia
Primary
Concomitant
Vomiting Hospitalization 5/1/2006 33 Female 9/1/2006 Physician United States
Primary
Secondary
Concomitant
Infection Other Serious 6/26/2004 Male 121 lb 9/18/2006 Physician United Kingdom
Primary
Concomitant
Therapy Non-responder Other Serious Male 9/25/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 8/31/2006 0 Male 9/22/2006 Finland
Primary
Concomitant
Staphylococcal Infection Life Threatening 5/8/2006 69 Male 9/21/2006 Other Health Professional Japan
Primary
Concomitant
Staphylococcal Infection Life Threatening 5/1/2006 69 Male 9/29/2006 Japan
Primary
Concomitant
Tumour Lysis Syndrome Required Intervention 1/1/2006 37 Female 9/28/2006 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Required Intervention 8/30/2006 37 Female 10/13/2006 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 8/1/2006 85 Female 10/26/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 3 Male 11/6/2006
Primary
Concomitant
Renal Failure Acute Hospitalization 7/6/2006 77 Male 11/10/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/3/2006 62 Male 11/14/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 8/31/2006 0 Male 11/13/2006 Other Health Professional Finland
Primary
Concomitant
Splenic Infarction Required Intervention 4/19/2006 Male 12/15/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 3 Male 1/9/2007 Consumer Australia
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 3/14/2006 20 Male 234 lb 12/29/2006 Consumer United States
Primary
Concomitant
Respiratory Failure Life Threatening 1/3/2007 30 Male 168 lb 1/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Disability 9/27/2005 Male 132 lb 3/16/2007 Japan
Primary
Concomitant
Drug Level Decreased Other Serious 31 Female 3/19/2007
Primary
Concomitant
Interacting
Neuropathy Peripheral Other Serious 12/15/2006 42 Male 207 lb 3/14/2007 Physician United States
Primary
Concomitant
Sepsis Hospitalization 11/25/2006 82 Female 3/20/2007 Other Health Professional Australia
Primary
Concomitant
Sinus Tachycardia Other Serious 3/8/2007 11 Female 53 lb 3/30/2007 Physician United States
Primary
Concomitant
Vena Cava Thrombosis Life Threatening 2/23/2004 41 Female 4/9/2007 Physician Sweden
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 12/15/2006 42 Male 207 lb 4/10/2007 Physician
Primary
Concomitant
Nephritis Interstitial Other Serious 56 5/1/2007 Consumer Australia
Primary
Concomitant
Visual Disturbance Other Serious 1/20/2007 21 Male 150 lb 5/8/2007 Pharmacist United States
Primary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 3/25/2007 Male 193 lb 5/10/2007 Physician United States
Primary
Secondary
Concomitant
Vena Cava Thrombosis Life Threatening 2/23/2004 41 Female 5/11/2007 Physician Sweden
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/3/2006 62 Male 6/27/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 7/10/2007 Other Health Professional Sweden
Primary
Concomitant
Systemic Mycosis Life Threatening 4/1/2006 49 Female 99 lb 7/13/2007 Physician Austria
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/3/2006 62 Male 7/19/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/11/2007 9 Female 56 lb 7/16/2007 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 57 Female 8/1/2007 Physician Italy
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 8/3/2007 Other Health Professional Sweden
Primary
Concomitant
Weight Decreased Hospitalization 5/11/2007 9 Female 56 lb 7/27/2007 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/1/2007 59 Male 260 lb 8/3/2007 Other Health Professional United States
Primary
Secondary
Cardiac Arrest Life Threatening 11/12/2006 Female 174 lb 8/7/2007 Australia
Primary
Secondary
Concomitant
Septic Shock Other Serious 21 Male 8/8/2007 Other Health Professional Korea, Republic Of
Primary
Secondary
Pyrexia Other Serious 2 Male 8/17/2007 Physician Brazil
Primary
Concomitant
Venoocclusive Disease Life Threatening 7/12/2007 39 Male 8/21/2007 Physician United States
Primary
Secondary
Concomitant
Cerebral Artery Thrombosis Life Threatening 2/9/2006 9/4/2007 Physician Argentina
Primary
Concomitant
Vena Cava Thrombosis Life Threatening 12/13/2006 9/10/2007 Physician Argentina
Primary
Concomitant
Atrial Thrombosis Life Threatening 2/24/2006 0 Female 7 lb 9/10/2007 Physician Argentina
Primary
Concomitant
Somnolence Hospitalization 8/1/2007 8 Male 88 lb 9/11/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Superinfection Hospitalization 11/25/2006 82 Female 9/18/2007 Other Health Professional Australia
Primary
Concomitant
Vomiting Other Serious 8 Male 10/2/2007
Primary
Secondary
Concomitant
Vena Cava Thrombosis Life Threatening 12/13/2006 10/3/2007 Physician Argentina
Primary
Concomitant
Atrial Thrombosis Life Threatening 2/24/2006 0 Female 7 lb 10/3/2007 Physician Argentina
Primary
Concomitant
Varicose Vein Life Threatening 6/15/2007 67 Male 190 lb 10/1/2007 Physician United States
Primary
Concomitant
Sepsis Hospitalization 1/1/2007 59 Male 260 lb 10/11/2007 Other Health Professional United States
Primary
Secondary
Somnolence Other Serious 8/1/2007 8 Male 88 lb 10/12/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 1/3/2007 58 Female 112 lb 10/9/2007 Pharmacist United States
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 9/23/2007 Male 192 lb 10/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebral Artery Thrombosis Life Threatening 2/9/2006 10/18/2007 Physician Argentina
Primary
Concomitant
Atrial Thrombosis Life Threatening 2/24/2006 0 Female 7 lb 10/18/2007 Physician Argentina
Primary
Concomitant
Vena Cava Thrombosis Life Threatening 12/13/2006 10/18/2007 Physician Argentina
Primary
Concomitant
Somnolence Other Serious 1/1/2007 8 Male 88 lb 10/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 10/7/2002 61 Female 11/1/2007 Physician
Primary
Concomitant
Pathogen Resistance Death 45 Male 11/1/2007 Other Health Professional Austria
Primary
Concomitant
Pathogen Resistance Death 45 Male 11/2/2007 Other Health Professional Austria
Primary
Concomitant
Pathogen Resistance Death 45 Male 11/2/2007 Other Health Professional Austria
Primary
Concomitant
Pneumonia Other Serious 8/6/2007 Female 117 lb 11/2/2007 Physician Japan
Primary
Concomitant
Staphylococcal Infection Life Threatening 1/1/2007 8 Male 88 lb 10/31/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenic Infection Other Serious 9/25/2007 46 Male 10/4/2007 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 8/1/2007 8 Male 88 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/11/2007 9 Female 56 lb 11/2/2007 United States
Primary
Secondary
Concomitant
Pyrexia Death 9/20/2007 Female 130 lb 11/13/2007 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2007 Female 11/14/2007 Pharmacist United Kingdom
Primary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 8/18/2007 8 Male 88 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10 Male 11/8/2007 Sweden
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/2/2007 15 Female 208 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 126 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 11/5/2007 15 Female 208 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 7/12/2007 39 Male 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Staphylococcal Death 9/5/2007 Female 130 lb 12/14/2007 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10 Male 12/14/2007 Sweden
Primary
Secondary
Concomitant
Respiratory Rate Increased Hospitalization 12/4/2007 66 Female 210 lb 12/12/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/11/2007 9 Female 56 lb 12/13/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 10/6/2007 36 Male 12/28/2007 Physician Australia
Primary
Secondary
Concomitant
Viral Infection Death 11/30/2007 51 Female 106 lb 12/28/2007 Physician Belgium
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 8/6/2007 Female 117 lb 1/4/2008 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 8/6/2007 Female 117 lb 1/8/2008 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 1/1/2007 59 Male 260 lb 1/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/3/2007 58 Female 112 lb 1/22/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 5/11/2007 9 Female 56 lb 12/13/2007 United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 1/19/2008 Male 133 lb 1/29/2008 United States
Primary
Secondary
Concomitant
Haemorrhage Intracranial Disability 1/18/2008 Male 2/8/2008 Physician Spain
Primary
Concomitant
Rash Maculo-papular Life Threatening 12/6/2007 57 Female 2/15/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Rash Maculo-papular Life Threatening 12/6/2007 57 Female 2/19/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 8/6/2007 Female 117 lb 2/21/2008 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 12/6/2007 57 Female 2/20/2008 Spain
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/13/2008 11 Female 44 lb 2/26/2008 Physician Ireland
Primary
Concomitant
Nephritis Interstitial Life Threatening 12/6/2007 57 Female 3/4/2008 Spain
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 10/5/2007 55 Male 3/13/2008 Pharmacist United States
Primary
Secondary
Vomiting Hospitalization 1/13/2008 11 Female 44 lb 3/13/2008 Ireland
Primary
Concomitant
Aspartate Aminotransferase Increased Life Threatening 2/20/2008 10 Male 54 lb 3/19/2008 Pharmacist United States
Primary
Concomitant
Septic Shock Required Intervention 1/23/2008 56 Male 293 lb 3/20/2008 Physician Germany
Primary
Concomitant
Sepsis Hospitalization 7/21/2006 54 Male 134 lb 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Visual Disturbance Other Serious 1/24/2008 Male 121 lb 3/31/2008 Physician Australia
Primary
Concomitant
Transaminases Increased Hospitalization 12/30/2007 5 Male 42 lb 4/3/2008 Physician Belgium
Primary
Concomitant
Transaminases Increased Hospitalization 12/30/2007 5 Male 42 lb 4/7/2008 Physician Belgium
Primary
Concomitant
Protein Total Decreased Other Serious Male 176 lb 4/21/2008 Pharmacist Australia
Primary
Secondary
Concomitant
Cardiac Failure Death 3/8/2008 14 Female 4/25/2008 Physician Italy
Primary
Secondary
Concomitant
Vision Blurred Other Serious 12/24/2007 41 Female 168 lb 3/12/2008 Pharmacist United States
Primary
Concomitant
Staphylococcal Sepsis Other Serious 3/1/2008 49 Male 90 lb 5/6/2008 Pharmacist United States
Primary
Concomitant
Cardiac Failure Death 3/8/2008 14 Female 5/6/2008 Physician Italy
Primary
Secondary
Concomitant
Pneumonia Other Serious 13 Female 5/16/2008 Physician Belgium
Primary
Concomitant

Drug Data