Melphalan combined with Thalomid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Other Serious NotSpecified 8/17/2006 Physician United States
Primary
Concomitant
Syncope Hospitalization 1/27/2008 77 Male 2/22/2008 Physician Italy
Primary
Secondary
Concomitant
Swelling Other Serious 8/2/2001 Male 200 lb 7/31/2008 United States
Primary
Secondary
Concomitant
Aortic Aneurysm Rupture Other Serious 5/1/2008 Male 8/25/2008 Physician United States
Primary
Concomitant
Thoracic Vertebral Fracture Other Serious 9/16/2007 Female 9/3/2008 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/1/2008 Male 9/15/2008 Physician United States
Primary
Secondary
Concomitant
Sudden Death Other Serious 10/1/2008 Italy
Primary
Secondary
Concomitant
Sinus Tachycardia Required Intervention 7/19/2006 65 Female 1/22/2007 Physician United States
Primary
Secondary
Pneumonia Hospitalization 9/21/2008 Female 177 lb 10/20/2008 United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 1/1/2008 Female 10/20/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/27/2008 Physician Greece
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 11/8/2008 Female 132 lb 11/21/2008 France
Primary
Secondary
Concomitant
Neoplasm Other Serious 12/11/2008 Portugal
Primary
Concomitant
Somnolence Death 3/22/2007 Female 12/24/2008 Canada
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 50 Female 12/30/2008 Physician United States
Primary
Concomitant
Respiratory Syncytial Virus Infection Hospitalization 1/13/2009 Female 178 lb 2/12/2009 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/18/2008 Female 205 lb 2/16/2009 Physician Germany
Primary
Concomitant
Somnolence Death 3/22/2007 Female 3/2/2009 Canada
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/18/2008 Female 205 lb 3/4/2009 Physician Germany
Primary
Concomitant
Somnolence Death 3/22/2007 Female 4/7/2009 Canada
Primary
Secondary
Concomitant
Nodal Arrhythmia Life Threatening 2/24/2009 Male 128 lb 4/10/2009 Australia
Primary
Secondary
Concomitant
Interacting
Skin Nodule Other Serious 4/14/2009 Other Health Professional Poland
Primary
Secondary
Pancytopenia Other Serious 61 Female 4/14/2009 Other Health Professional Netherlands
Primary
Concomitant
Vomiting Other Serious 4/14/2009 Other Health Professional Austria
Primary
Secondary
Concomitant
Pancytopenia Other Serious 61 Female 4/16/2009 Other Health Professional Netherlands
Primary
Concomitant
Haemorrhage Other Serious 4/24/2009 Italy
Primary
Secondary
Concomitant
Haemorrhage Other Serious 4/29/2009 Italy
Primary
Secondary
Renal Failure Other Serious 5/1/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/7/2009 Other Health Professional France
Primary
Secondary
Concomitant
Multi-organ Failure Death 1/1/2009 Female 5/18/2009 Physician United States
Primary
Concomitant
Nodal Arrhythmia Life Threatening 2/24/2009 Male 128 lb 6/9/2009 Australia
Primary
Secondary
Concomitant
Interacting
Staphylococcal Bacteraemia Other Serious 1/1/2009 Male 174 lb 6/11/2009 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 3/18/2008 Female 205 lb 6/23/2009 Physician Germany
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/11/2009 Female 141 lb 7/1/2009 Canada
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2009 Male 174 lb 7/17/2009 Physician United States
Primary
Concomitant
Uterine Leiomyoma 5/28/2008 Female 233 lb 7/23/2009 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/11/2009 Female 141 lb 7/24/2009 Canada
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/1/2009 Male 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/1/2009 Female 153 lb 7/31/2009 United States
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious 2/1/2008 Female 8/3/2009 Physician United States
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious 1/1/2008 74 Female 8/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious 2/1/2008 Female 9/18/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 10/20/2009 Netherlands
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/8/2009 Female 10/26/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/11/2009 Netherlands
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 1/1/2009 Male 163 lb 11/24/2009 United States
Primary
Secondary
Concomitant
Sedation Other Serious 12/9/2009 Other Health Professional Czech Republic
Primary
Concomitant
Neutrophil Count Decreased Other Serious 1/1/2009 Male 163 lb 12/16/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2000 Male 1/18/2010 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 1/1/2009 Male 3/4/2010 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/2000 Female 140 lb 3/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 71 7/14/2010 Italy
Primary
Secondary
Renal Failure Other Serious 1/13/2010 85 Female 207 lb 7/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/17/2005 60 Male 7/15/2010 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/2000 52 Female 140 lb 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nodal Arrhythmia Life Threatening 2/24/2009 71 Male 128 lb 7/22/2010 Physician Australia
Primary
Secondary
Concomitant
Interacting
Renal Failure Acute Other Serious 1/1/2009 55 Male 186 lb 8/6/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 69 Male 8/30/2010 Japan
Primary
Secondary
Sepsis Other Serious 8/16/2010 76 Female 147 lb 9/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 5/1/2000 75 Female 9/8/2010 United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Life Threatening 9/4/2010 88 Male 123 lb 11/1/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Syncope Other Serious 10/1/2010 47 Male 12/20/2010 Physician United States
Primary
Concomitant
Multiple Myeloma Other Serious Female 12/29/2010 Other Health Professional United States
Primary
Concomitant
Dermal Cyst Other Serious 1/1/2000 52 Female 140 lb 1/5/2011 Lawyer United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 10/11/2010 80 Male 210 lb 1/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Death 10/6/2010 47 Male 1/17/2011 Physician United States
Primary
Concomitant
Neoplasm Malignant Other Serious 5/1/2000 75 Female 1/19/2011 Lawyer United States
Primary
Secondary
Concomitant
Multiple Myeloma Hospitalization 4/8/2010 62 Female 1/20/2011 Physician United States
Primary
Concomitant
Endometrial Cancer Other Serious 8/20/2009 61 Female 141 lb 1/24/2011 Other Health Professional United States
Primary
Secondary
Death Death 68 1/24/2011 Other Health Professional United States
Primary
Secondary
Breast Cancer Other Serious 61 Male 1/26/2011 Other Health Professional United States
Primary
Secondary
Meningitis Herpes Death 59 1/26/2011 Other Health Professional United States
Primary
Secondary
Hepatic Failure Death 38 Female 1/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 69 1/28/2011 Other Health Professional United States
Primary
Secondary
Complications Of Bone Marrow Transplant Other Serious 48 1/28/2011 Other Health Professional United States
Primary
Secondary
Squamous Cell Carcinoma Other Serious 59 1/28/2011 Other Health Professional United States
Primary
Secondary
Astrocytoma Death 68 1/28/2011 Other Health Professional United States
Primary
Secondary
Hepatotoxicity Other Serious Female 1/31/2011 Physician Australia
Primary
Concomitant
Multiple Myeloma Other Serious 69 1/31/2011 Other Health Professional United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 56 1/31/2011 Other Health Professional United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 54 1/31/2011 Other Health Professional United States
Primary
Secondary
Squamous Cell Carcinoma Other Serious 56 1/31/2011 Other Health Professional United States
Primary
Secondary
Performance Status Decreased Disability 12/1/2010 82 Female 2/4/2011 Other Health Professional United States
Primary
Concomitant
Syncope Other Serious 12/7/2010 47 Male 2/7/2011 Physician United States
Primary
Concomitant
Colon Cancer Other Serious 58 Male 2/10/2011 Other Health Professional United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 63 Male 2/10/2011 Other Health Professional United States
Primary
Secondary
Neuropathy Peripheral Other Serious 5/19/2009 76 Female 191 lb 2/14/2011 Physician United States
Primary
Concomitant
Hepatotoxicity Hospitalization 7/16/2010 67 Female 139 lb 2/14/2011 Physician Australia
Primary
Concomitant
Hypertonic Bladder Other Serious 1/1/2005 60 Male 2/18/2011 Lawyer United States
Primary
Concomitant
Pathological Fracture Hospitalization 2/5/2011 71 Male 2/22/2011 Physician Australia
Primary
Concomitant
Multiple Myeloma Disability 12/1/2010 82 Female 3/7/2011 Other Health Professional United States
Primary
Concomitant
Death Other Serious 3/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Seroma Other Serious 1/1/2000 52 Female 140 lb 3/10/2011 Physician United States
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 7/16/2010 67 Female 139 lb 3/10/2011 Physician Australia
Primary
Concomitant
Diarrhoea Other Serious 11/1/2010 75 Female 3/29/2011 Consumer Australia
Primary
Concomitant
Micturition Urgency Other Serious 1/1/2010 77 Female 191 lb 4/4/2011 Physician United States
Primary
Concomitant
Lymphocytic Leukaemia Other Serious 11/30/2010 74 Male 218 lb 4/4/2011 Physician United States
Primary
Secondary
Concomitant
Iliac Artery Thrombosis Other Serious 1/1/2000 52 Female 140 lb 4/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis Cholestatic Hospitalization 7/16/2010 67 Female 139 lb 4/11/2011 Physician Australia
Primary
Concomitant
Lymphocytic Leukaemia Other Serious 11/30/2010 74 Male 218 lb 4/15/2011 Physician United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 1/1/2000 52 Female 140 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 1/26/2011 74 Female 206 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertension Other Serious 1/1/2005 60 Male 4/26/2011 Other Health Professional United States
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 10/11/2010 80 Male 210 lb 4/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 1/1/2009 89 Male 163 lb 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Pneumonia Viral Hospitalization 4/4/2011 70 Female 187 lb 5/3/2011 Physician United States
Primary
Concomitant
Atelectasis Other Serious 1/1/2005 60 Male 5/5/2011 Lawyer United States
Primary
Concomitant
Pollakiuria Other Serious 1/1/2010 77 Female 191 lb 5/9/2011 Physician United States
Primary
Concomitant
Cardio-respiratory Arrest Death 12/3/2008 51 Female 5/9/2011 Other Health Professional United States
Primary
Secondary
Pyrexia Hospitalization 11/21/2010 70 Female 9/8/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 1/1/2011 63 Male 9/13/2011 Other Health Professional United States
Primary
Secondary
Carcinoid Tumour Pulmonary Death 8/28/2007 69 Female 9/13/2011 Other Health Professional United States
Primary
Secondary
Multiple Myeloma Other Serious 6/7/2007 71 9/13/2011 Other Health Professional United States
Primary
Secondary
Hepatic Function Abnormal Hospitalization 1/1/2003 77 Female 1/6/2012 United States
Primary
Secondary
Concomitant
Disorientation Hospitalization 1/1/2003 77 Female 1/19/2012 United States
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 2/23/2012 Physician United States
Primary
Secondary
Concomitant
Lymphadenectomy Other Serious 6/28/2010 72 Female 137 lb 5/24/2012 Physician Netherlands
Primary
Secondary
Pancreatitis Hospitalization 2/6/2012 83 Female 99 lb 12/17/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Malignant Melanoma Death 8/26/2008 78 Male 210 lb 11/16/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Endometrial Cancer Other Serious 9/30/2009 61 Female 141 lb 8/5/2013 Other Health Professional Us
Primary
Secondary
Squamous Cell Carcinoma Of Skin Death 4/5/2010 69 Female 3/22/2013 Other Health Professional Us
Primary
Secondary
Leukaemia Granulocytic Other Serious 11/30/2010 74 Male 218 lb 3/21/2013 Physician Us
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/5/2010 86 Female 135 lb 9/27/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 9/12/2012 Country Not Specified
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 11/3/2011 81 Male 143 lb 10/10/2012 Physician Us
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 8/27/2012 81 Female 154 lb 9/27/2012 Pharmacist Au
Primary
Concomitant
Acute Myeloid Leukaemia Death 8/17/2011 60 Male 9/12/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Hospitalization 12/17/2008 80 Female 104 lb 12/12/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Bladder Transitional Cell Carcinoma Other Serious 4/26/2010 82 Male 12/20/2012 Physician Us
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 10/29/2010 82 Male 175 lb 1/8/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Invasive Ductal Breast Carcinoma Other Serious 7/27/2010 Female 9/20/2012 Physician Us
Primary
Secondary
Lung Adenocarcinoma Other Serious 7/2/2010 76 Male 134 lb 1/9/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Plasma Cell Myeloma Death 10/17/2012 61 Male 10/22/2012 Physician Ca
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 9/17/2012 80 Male 179 lb 11/12/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Transitional Cell Carcinoma Other Serious 10/3/2012 73 Male 133 lb 2/20/2013 Physician Ca
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 1/24/2013 75 Female 189 lb 3/11/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 10/24/2012 69 Female 5/3/2013 Physician Us
Primary
Secondary
Concomitant
Plasma Cell Myeloma Death 1/2013 Male 3/27/2013 Physician Us
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 3/4/2013 84 Male 8/14/2013 Physician Ca
Primary
Secondary
Squamous Cell Carcinoma Of The Oral Cavity Other Serious 1/26/2012 81 Male 202 lb 5/9/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/10/2012 83 Female 132 lb 10/23/2012 Physician Us
Primary
Secondary
Concomitant
Acute Lymphocytic Leukaemia Other Serious 4/5/2013 61 Male 260 lb 5/22/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Malignant Neoplasm Of Unknown Primary Site Other Serious 1/20/2011 NotSpecified 5/8/2013 Physician Us
Primary
Secondary
Dysphagia Death 5/1/2013 78 Female 139 lb 5/29/2013 Physician Us
Primary
Concomitant
Adverse Drug Reaction Other Serious 75 Female 161 lb 6/17/2013 Other Health Professional Us
Primary
Concomitant
Plasma Cell Myeloma Other Serious 62 Male 384 lb 6/24/2013 Other Health Professional Us
Primary
Concomitant
Drug Ineffective Other Serious 35 Male 408 lb 6/28/2013 Other Health Professional Us
Primary
Concomitant
Toxicity To Various Agents Other Serious 88 Male 317 lb 7/8/2013 Other Health Professional Us
Primary
Concomitant
Adverse Drug Reaction Other Serious 68 Male 210 lb 7/15/2013 Other Health Professional Us
Primary
Concomitant
Wound Dehiscence Other Serious 3/17/2004 56 Female 140 lb 8/13/2013 Physician Us
Primary
Secondary
Concomitant

Drug Data