Melphalan combined with Thalidomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tooth Extraction Other Serious 1/1/2003 79 Male 1/13/2006 United States
Primary
Concomitant
Wound Debridement Other Serious 6/18/1999 51 Male 1/25/2006 United States
Primary
Secondary
Concomitant
Myopathy Steroid Death 1/5/2006 71 Male 2/2/2006 Pharmacist United States
Primary
Concomitant
Sinusitis Hospitalization 1/15/2006 65 Male 225 lb 2/16/2006 Physician United States
Primary
Secondary
Osteonecrosis Other Serious Female 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 Male 2/24/2006 United States
Primary
Secondary
Concomitant
Hypoaesthesia 70 Male 2/28/2006 Consumer United States
Primary
Secondary
Wound Drainage Other Serious 1/1/2001 52 Male 3/15/2006 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 3/24/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/1/2003 70 Male 108 lb 3/30/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 68 Male 4/13/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 Male 5/8/2006 United States
Primary
Secondary
Concomitant
Melaena Other Serious 60 Female 5/22/2006 Australia
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 5/31/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 Male 6/1/2006 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2000 69 Male 6/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2000 69 Male 6/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Soft Tissue Disorder Other Serious 1/1/2005 68 Male 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2003 61 Male 6/22/2006 United States
Primary
Concomitant
Wound Debridement Other Serious 12/1/2003 70 Male 108 lb 6/29/2006 Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2003 61 Male 6/30/2006 United States
Primary
Concomitant
Wound Treatment Other Serious 44 Female 7/5/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2003 61 Male 187 lb 7/21/2006 Physician Germany
Primary
Concomitant
Tooth Extraction Other Serious 2/1/2003 61 Male 7/25/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2002 62 Male 8/16/2006 United States
Primary
Secondary
Concomitant
Plasmacytoma Other Serious 54 Male 9/21/2006 Consumer United States
Primary
Secondary
Thrombophlebitis Other Serious 1/1/2005 51 Male 10/3/2006 Consumer United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 5/5/2005 61 Female 10/3/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/1/2005 62 Male 152 lb 10/4/2006 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2000 69 Male 10/23/2006 United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 10/25/2006 Physician United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 Male 11/22/2006 United States
Primary
Secondary
Concomitant
Disease Progression Hospitalization 9/1/2004 64 Male 11/13/2006 Physician United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 44 Female 12/12/2006
Primary
Secondary
Pain Other Serious 44 Female 12/20/2006 Physician Italy
Primary
Secondary
Wound Debridement Disability 12/1/2005 63 Female 1/3/2007 Switzerland
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 54 Male 1/12/2007 United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 9/1/2006 83 Female 1/12/2007 Switzerland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/20/2003 77 Female 1/13/2007 United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 1/15/2007 Physician United States
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy 54 Male 1/16/2007 United States
Primary
Secondary
Wound Debridement Other Serious 2/1/2003 54 Male 1/25/2007 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 73 Male 2/2/2007 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 2/19/2007 Physician Japan
Primary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 3/5/2007 Physician Japan
Primary
Concomitant
Spinal Compression Fracture Other Serious 8/18/2006 68 Male 176 lb 3/7/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/1/2004 67 Female 3/15/2007 Japan
Primary
Concomitant
Tooth Extraction Disability 2/1/2005 84 Male 3/19/2007 France
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 3/16/2007 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 2/27/2007 68 Female 4/24/2007 Physician United States
Primary
Secondary
Concomitant
Hepatitis Acute Life Threatening 3/26/2007 51 Female 128 lb 4/19/2007 Pharmacist United States
Primary
Concomitant
Soft Tissue Infection Disability 12/1/2006 83 Male 4/28/2007 Other Health Professional Australia
Primary
Concomitant
Tooth Extraction Other Serious 12/1/2004 54 Female 166 lb 5/7/2007 United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2005 73 Male 239 lb 5/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/23/2006 78 Male 161 lb 5/26/2007 Physician United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 5/23/2006 78 Male 161 lb 5/26/2007 Physician United Kingdom
Primary
Concomitant
Tooth Extraction 2/1/2007 47 Male 154 lb 5/31/2007 Physician Germany
Primary
Concomitant
Tooth Extraction 2/1/2007 47 Male 154 lb 5/31/2007 Physician Germany
Primary
Concomitant
Wound Drainage Other Serious 2/1/2005 73 Male 239 lb 6/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2004 47 Female 6/8/2007 Physician Australia
Primary
Secondary
Concomitant
Hepatitis Acute Other Serious 51 Female 5/17/2007 Pharmacist United States
Primary
Concomitant
Wound Debridement Other Serious 2/1/2003 56 Male 6/15/2007 United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/1/2006 76 Male 6/20/2007 Other Health Professional Finland
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2005 60 Female 7/20/2007 United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2005 60 Female 7/20/2007 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/9/2007 83 Male 8/28/2007 Consumer United States
Primary
Secondary
Urinary Tract Infection Other Serious 1/1/1997 64 Female 9/4/2007 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/1997 64 Female 9/4/2007 United States
Primary
Secondary
Concomitant
West Nile Viral Infection Other Serious 8/18/2006 68 Male 176 lb 9/26/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/1/2004 67 Female 10/16/2007 Japan
Primary
Concomitant
Dementia Other Serious 1/1/2007 55 Male 10/22/2007 Physician Japan
Primary
Secondary
Concomitant
Dementia Hospitalization 11/1/2006 55 Male 10/29/2007 Physician Japan
Primary
Secondary
Concomitant
Dementia Hospitalization 11/1/2006 55 Male 11/19/2007 Physician Japan
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 1/1/2005 68 Male 201 lb 12/11/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/20/2003 77 Female 12/18/2007 Physician United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 56 Male 12/18/2007 United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 12/26/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 9/4/2007 60 Male 2/6/2008 Physician Japan
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 1/1/2007 55 Male 2/6/2008 United States
Primary
Concomitant
Hypoaesthesia 1/30/2007 77 Female 2/13/2008 Consumer United States
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 1/1/2005 67 Male 201 lb 2/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 11/25/1998 43 Female 170 lb 2/29/2008 United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 7/1/2006 Female 3/11/2008 Physician Italy
Primary
Concomitant
Visual Disturbance Other Serious 11/25/1998 43 Female 170 lb 3/18/2008 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 3/9/2007 71 Male 4/8/2008 Physician Australia
Primary
Concomitant
Tooth Extraction Other Serious 3/7/2005 Male 4/18/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 1/1/2007 61 Female 128 lb 4/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Leukaemia Hospitalization 2/6/2008 64 Male 198 lb 4/24/2008 Physician Israel
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2007 55 Male 5/21/2008 Physician United States
Primary
Concomitant
Syncope Hospitalization 1/27/2008 77 Male 5/22/2008 Physician Italy
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 9/4/2007 Male 123 lb 7/2/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 12/20/2006 72 Male 90 lb 7/21/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Guillain-barre Syndrome Hospitalization 47 Male 8/4/2008 Other Health Professional United States
Primary
Secondary
Guillain-barre Syndrome Other Serious 47 Male 8/11/2008 United States
Primary
Secondary
Guillain-barre Syndrome Other Serious 47 Male 8/9/2008 United States
Primary
Secondary
Wound Decomposition Other Serious 9/1/2003 Male 130 lb 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 47 Male 8/20/2008 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2007 Male 9/9/2008 Other Health Professional France
Primary
Concomitant
Sequestrectomy Other Serious 5/11/2007 Female 9/9/2008 Other Health Professional France
Primary
Secondary
Concomitant
Haemoptysis Other Serious 1/1/2007 Male 10/14/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/17/2008 Female 10/17/2008 Italy
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 57 Female 11/4/2008 Other Health Professional Japan
Primary
Concomitant
Tooth Extraction Other Serious 4/1/2007 57 Female 11/13/2008 Other Health Professional Japan
Primary
Concomitant
Tooth Extraction Other Serious 4/1/2007 57 Female 12/8/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 11/8/2008 Female 146 lb 12/17/2008 France
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 71 Male 12/30/2008 Other Health Professional France
Primary
Concomitant
Osteonecrosis Other Serious 12/1/2007 57 Female 12/30/2008 Other Health Professional Japan
Primary
Secondary
Pneumonitis Hospitalization Male 1/5/2009 Physician France
Primary
Concomitant
Squamous Cell Carcinoma Death 4/1/2002 6 Male 1/7/2009 Italy
Primary
Secondary
Pulmonary Toxicity Hospitalization 71 Male 1/9/2009 Other Health Professional France
Primary
Concomitant
Wound Drainage Other Serious 1/1/2001 Male 150 lb 1/13/2009 United States
Primary
Secondary
Concomitant
Vertebroplasty Other Serious 1/1/2003 Male 1/15/2009 Physician United States
Primary
Concomitant
Sequestrectomy Other Serious 78 Female 1/16/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 12/1/2007 57 Female 1/16/2009 Other Health Professional Japan
Primary
Secondary
Tooth Abscess Disability 10/1/2004 Female 1/19/2009 United States
Primary
Concomitant
Somnolence Other Serious 3/22/2008 78 Female 1/19/2009 Consumer Canada
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/8/2008 Female 146 lb 1/29/2009 France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 68 Female 2/3/2009 Italy
Primary
Concomitant
Stem Cell Transplant Other Serious 4/22/2005 Male 2/17/2009 Pharmacist United States
Primary
Concomitant
Respiratory Syncytial Virus Infection Hospitalization 1/13/2009 49 Female 178 lb 2/19/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Infarction Hospitalization 1/19/2009 Male 168 lb 2/24/2009 Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/9/2009 Male 172 lb 3/2/2009 Germany
Primary
Secondary
Stem Cell Transplant Other Serious 4/22/2005 Male 3/4/2009 Pharmacist United States
Primary
Concomitant
Vomiting Death 50 Male 3/9/2009 Consumer United States
Primary
Secondary
Concomitant
Nervous System Disorder Death 54 Male 3/9/2009 Consumer United States
Primary
Secondary
Concomitant
Dermatitis Exfoliative Other Serious 8/16/2008 77 Male 3/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 2/9/2009 67 Male 3/11/2009 Physician Germany
Primary
Secondary
Spinal Fracture Other Serious 3/3/2009 Male 3/12/2009 Turkey
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 1/19/2009 Male 168 lb 3/13/2009 Germany
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 2/26/2009 Male 104 lb 3/16/2009 France
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/1/2009 76 Male 3/16/2009 Physician Italy
Primary
Secondary
Concomitant
Tibia Fracture Other Serious 8/1/2003 62 Male 3/18/2009 Physician Australia
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/25/2008 70 Male 176 lb 3/23/2009 Physician Germany
Primary
Secondary
Concomitant
Tenderness Other Serious 4/22/2005 Male 3/23/2009 Pharmacist United States
Primary
Concomitant
Sepsis Life Threatening 2/9/2009 Male 172 lb 3/25/2009 Germany
Primary
Secondary
Concomitant
Sudden Death Death 3/23/2009 Male 240 lb 3/27/2009 Russian Federation
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/9/2009 Male 172 lb 4/1/2009 Germany
Primary
Secondary
Concomitant
Sudden Death Death 2/1/2005 Male 240 lb 4/8/2009 Russian Federation
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/9/2009 Male 172 lb 4/13/2009 Germany
Primary
Secondary
Concomitant
Pyrexia 60 Male 4/9/2009 Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 4/14/2009 Consumer United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 2/11/2009 Female 4/15/2009 Physician Greece
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 1/1/2005 Male 201 lb 4/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 2/9/2009 Male 4/20/2009 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/3/2009 Male 4/20/2009 Physician Italy
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/27/2009 Italy
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 2/13/2009 Female 132 lb 4/27/2009 France
Primary
Concomitant
Febrile Neutropenia Other Serious 4/27/2009 Consumer United Kingdom
Primary
Secondary

Drug Data