Melphalan combined with Revlimid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tooth Extraction Other Serious 2/1/2003 61 Male 6/22/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 2/1/2003 61 Male 6/30/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 2/1/2003 61 Male 7/25/2006 United States
Primary
Concomitant
Fatigue Other Serious 9/8/2006 43 Female 9/26/2006 Physician United States
Primary
Concomitant
Swelling Other Serious 1/1/2005 60 Female 7/20/2007 United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2005 60 Female 7/20/2007 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/19/2007
Primary
Secondary
Concomitant
Rebound Effect Other Serious 11/19/2007
Primary
Secondary
Concomitant
Rebound Effect Other Serious 11/19/2007
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/1/2006 64 Male 12/19/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 12/13/2007 Female 12/18/2007 Pharmacist United States
Primary
Concomitant
Tooth Abscess Other Serious 1/1/2007 55 Male 2/6/2008 United States
Primary
Concomitant
Urinary Tract Infection Required Intervention 12/1/2007 76 Female 12/18/2007 Pharmacist United States
Primary
Secondary
Concomitant
Tenderness Other Serious 1/1/2003 60 Male 4/2/2008 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 1/1/2007 61 Female 128 lb 4/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2007 55 Male 5/21/2008 Physician United States
Primary
Concomitant
Rash Other Serious 5/15/2008 Male 5/21/2008 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/23/2008 Male 148 lb 8/13/2008 Sweden
Primary
Secondary
Concomitant
Fatigue Hospitalization 6/16/2008 Male 8/18/2008 Australia
Primary
Secondary
Rash Death Female 8/25/2008 Physician Ireland
Primary
Concomitant
Intestinal Perforation Life Threatening 8/11/2008 Male 8/25/2008 Italy
Primary
Secondary
Concomitant
Sepsis Life Threatening 3/26/2008 Female 192 lb 9/3/2008 United States
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 3/18/2008 Female 138 lb 9/4/2008 Canada
Primary
Secondary
Diverticulitis Hospitalization 2/27/2008 Female 121 lb 9/5/2008 Greece
Primary
Secondary
Loss Of Consciousness Hospitalization 2/28/2008 Female 132 lb 9/8/2008 Greece
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/29/2008 Female 9/8/2008 Italy
Primary
Secondary
Concomitant
White Blood Cell Disorder Other Serious 8/24/2008 64 Female 145 lb 9/9/2008 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/18/2008 Male 9/10/2008 Italy
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 9/5/2008 Male 139 lb 9/12/2008 Greece
Primary
Secondary
Scrotal Swelling Death 9/12/2008 Male 188 lb 9/18/2008 Canada
Primary
Secondary
Rash Hospitalization 2/7/2008 Female 9/19/2008 Physician Ireland
Primary
Concomitant
Nausea Hospitalization 9/12/2008 Female 107 lb 9/24/2008 Germany
Primary
Secondary
Cardiac Arrest Death 9/12/2008 Male 188 lb 10/1/2008 Canada
Primary
Secondary
Paraesthesia Hospitalization 1/1/2008 75 Female 10/1/2008 Physician United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 8/24/2008 Female 126 lb 10/6/2008 Belgium
Primary
Secondary
Hypocalcaemia Hospitalization 2/28/2008 Female 132 lb 10/7/2008 Greece
Primary
Secondary
Concomitant
Hypophosphataemia Other Serious 11/1/2007 Female 115 lb 10/13/2008 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/13/2007 Male 154 lb 10/17/2008 Austria
Primary
Secondary
Febrile Neutropenia Hospitalization 11/13/2007 Male 154 lb 10/17/2008 Austria
Primary
Secondary
Pneumonia Hospitalization 4/17/2008 Female 10/17/2008 Italy
Primary
Secondary
Concomitant
Blood Magnesium Decreased Hospitalization 11/7/2008 Female 210 lb 11/20/2008 United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 11/8/2008 Female 132 lb 11/21/2008 France
Primary
Secondary
Concomitant
Weight Decreased Disability 1/1/2008 Female 11/21/2008 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 9/23/2008 Male 152 lb 11/25/2008 Italy
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 11/15/2008 Female 181 lb 12/2/2008 Turkey
Primary
Secondary
Renal Failure Acute Hospitalization 11/1/2008 Female 210 lb 12/4/2008 United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 11/22/2008 Male 159 lb 12/5/2008 Russian Federation
Primary
Secondary
Pyrexia Hospitalization 9/26/2008 Male 152 lb 12/8/2008 Italy
Primary
Secondary
Concomitant
Sepsis Other Serious 12/10/2007 Female 12/10/2008 Australia
Primary
Secondary
Sepsis Other Serious 11/15/2008 Female 181 lb 12/11/2008 Turkey
Primary
Secondary
Renal Impairment Life Threatening 7/1/2008 Female 106 lb 12/11/2008 Belgium
Primary
Secondary
Autoimmune Thrombocytopenia Other Serious 2/15/2008 Male 12/11/2008 Physician Denmark
Primary
Concomitant
Multiple Myeloma Death 11/22/2008 Male 159 lb 12/15/2008 Russian Federation
Primary
Secondary
Pneumonitis Hospitalization 11/8/2008 Female 146 lb 12/17/2008 France
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/29/2008 Female 12/24/2008 Italy
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/2/2008 Female 106 lb 1/5/2009 Belgium
Primary
Secondary
Renal Failure Acute Life Threatening 7/2/2008 Female 106 lb 1/5/2009 Belgium
Primary
Secondary
Anaemia Life Threatening 4/28/2008 Female 1 lb 1/5/2009 Poland
Primary
Secondary
Renal Failure Acute Hospitalization 11/7/2008 Female 206 lb 1/6/2009 United States
Primary
Secondary
Concomitant
Somnolence Life Threatening 7/2/2008 Female 106 lb 1/7/2009 Belgium
Primary
Secondary
Concomitant
Anaemia Haemolytic Autoimmune Other Serious 12/1/2008 1/13/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 12/24/2008 Male 1/13/2009 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 11/18/2008 Female 2/5/2009 Physician United States
Primary
Concomitant
Sepsis Other Serious 12/9/2007 Female 2/10/2009 Australia
Primary
Secondary
Renal Failure Acute Life Threatening 7/2/2008 Female 106 lb 2/11/2009 Belgium
Primary
Secondary
Concomitant
Bile Duct Cancer Death 10/1/2008 Female 2/12/2009 France
Primary
Secondary
Stem Cell Transplant Other Serious 4/22/2005 Male 2/17/2009 Pharmacist United States
Primary
Concomitant
Hyperuricaemia Other Serious 6/2/2008 Male 204 lb 2/18/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/1/2008 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 11/12/2007 Male 138 lb 3/4/2009 Spain
Primary
Secondary
Stem Cell Transplant Other Serious 4/22/2005 Male 3/4/2009 Pharmacist United States
Primary
Concomitant
Agranulocytosis Hospitalization 9/25/2008 Male 3/5/2009 France
Primary
Secondary
Bile Duct Cancer Death 10/1/2008 Female 3/10/2009 France
Primary
Secondary
Dermatitis Exfoliative Other Serious 8/16/2008 77 Male 3/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pruritus Hospitalization 78 Male 3/13/2009 Consumer Germany
Primary
Secondary
Weight Increased Other Serious 7/6/2005 Male 3/18/2009 Physician United States
Primary
Concomitant
Right Ventricular Dysfunction Other Serious 7/1/2008 77 Male 3/19/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Tenderness Other Serious 4/22/2005 Male 3/23/2009 Pharmacist United States
Primary
Concomitant
Pruritus Hospitalization 78 Male 3/24/2009 Consumer Germany
Primary
Secondary
Concomitant
Pruritus Hospitalization 78 Male 3/25/2009 Consumer Germany
Primary
Secondary
Concomitant
Right Ventricular Dysfunction Other Serious 7/1/2008 77 Male 3/26/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 11/15/2008 Female 181 lb 3/27/2009 Turkey
Primary
Secondary
Concomitant
Renal Failure Life Threatening 3/1/2009 Male 168 lb 3/31/2009 Spain
Primary
Secondary
Weight Increased Other Serious 7/6/2005 Male 4/24/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 4/27/2009 Italy
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Life Threatening 11/4/2008 Female 97 lb 4/27/2009 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/28/2009 Other Health Professional Canada
Primary
Secondary
Sepsis Hospitalization 1/3/2009 Male 167 lb 4/30/2009 Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/6/2005 Male 5/1/2009 Physician United States
Primary
Concomitant
Thrombosis In Device Other Serious 5/4/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/5/2009 Italy
Primary
Secondary
Meningitis Hospitalization 4/22/2009 Female 152 lb 5/5/2009 Italy
Primary
Secondary
Concomitant
Vasculitis Other Serious 5/8/2009 Other Health Professional France
Primary
Secondary
Thrombocytopenia Other Serious 5/21/2009 Other Health Professional Canada
Primary
Secondary
Cerebrovascular Accident Death 5/21/2009 Other Health Professional Canada
Primary
Secondary
Stridor Hospitalization 5/4/2009 Female 145 lb 5/29/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/2/2009 Italy
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 1/1/2002 Male 6/8/2009 Physician United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 5/21/2009 Male 211 lb 6/15/2009 United States
Primary
Secondary
Concomitant
Pneumonia Death 6/10/2009 Female 154 lb 6/30/2009 Belarus
Primary
Secondary
Pathological Fracture Other Serious 6/22/2009 Male 210 lb 7/2/2009 United States
Primary
Secondary
Concomitant
Pseudomembranous Colitis Hospitalization 3/25/2008 Male 121 lb 7/6/2009 Czech Republic
Primary
Secondary
Pseudomembranous Colitis Hospitalization 3/25/2008 Male 121 lb 7/15/2009 Czech Republic
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 1/1/2002 Male 7/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Terminal State Other Serious 7/6/2009 Female 7/24/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2009 Male 7/27/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 12/9/2007 Female 7/29/2009 Australia
Primary
Secondary
Neutropenia Life Threatening 11/4/2008 Female 97 lb 7/29/2009 Physician France
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious 2/1/2008 Female 8/3/2009 Physician United States
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious 1/1/2008 74 Female 8/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 11/15/2008 Female 181 lb 9/17/2009 Turkey
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious 2/1/2008 Female 9/18/2009 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2002 Male 10/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 58 Male 10/14/2009 Other Health Professional Germany
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 10/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Laryngeal Oedema Other Serious 5/1/2009 Female 145 lb 10/26/2009 United States
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 5/29/2009 84 Female 11/3/2009 Other Health Professional France
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/21/2009 Male 163 lb 11/3/2009 United States
Primary
Secondary
Urinary Tract Infection Other Serious 10/12/2009 Female 11/9/2009 United States
Primary
Concomitant
Respiratory Distress Other Serious 5/4/2009 78 Female 11/17/2009 United States
Primary
Secondary
Concomitant
Laryngeal Oedema Other Serious 5/4/2009 Female 145 lb 11/18/2009 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2009 Male 141 lb 11/24/2009 Netherlands
Primary
Secondary
Concomitant
Constipation Hospitalization 10/21/2009 Male 163 lb 11/24/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/7/2009 83 Female 11/25/2009 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/2/2002 Female 125 lb 11/25/2009 United States
Primary
Secondary
Concomitant
Ultrasound Scan Hospitalization 6/1/2009 79 Male 12/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 11/6/2008 Male 12/10/2009 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 4/2/2002 Female 125 lb 12/16/2009 United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 4/26/2009 Male 172 lb 12/17/2009 Germany
Primary
Concomitant
Headache Disability Male 2/23/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/6/2005 Male 3/2/2010 Physician United States
Primary
Concomitant
Skin Ulcer Other Serious 1/1/2010 Male 3/5/2010 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 4/15/2010 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 3/1/2007 70 Female 4/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 7/14/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/16/2010 Physician United States
Primary
Secondary
Weight Decreased Other Serious 1/23/2001 44 Male 161 lb 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 7/19/2010 United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/1/2010 65 Male 7/20/2010 Consumer France
Primary
Secondary
Concomitant
Vasculitis Other Serious 7/21/2010 Physician Italy
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 77 Male 7/23/2010 Other Health Professional United States
Primary
Secondary
Weight Decreased Other Serious 4/1/2006 54 Male 7/29/2010 United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 7/5/2010 83 Female 8/3/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2009 55 Male 186 lb 8/6/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 8/6/2010 United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 12/27/2009 63 Male 8/17/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 8/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 5/29/2010 87 Female 8/19/2010 Physician United States
Primary
Concomitant
Respiratory Acidosis Hospitalization 8/6/2010 80 Female 113 lb 8/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 7/5/2010 83 Female 8/23/2010 Physician United States
Primary
Concomitant

Drug Data