Melphalan combined with Prednisone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tooth Extraction Other Serious 1/1/2003 79 Male 1/13/2006 United States
Primary
Concomitant
Rash Macular Other Serious 9/4/2005 77 Female 194 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 11/17/2005 75 Male 1/19/2006 Physician Spain
Primary
Concomitant
Tooth Extraction Other Serious 5/1/2005 60 Female 2/3/2006 Physician Spain
Primary
Secondary
Concomitant
Ischaemic Stroke Other Serious 82 Female 1/27/2006 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious Female 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 1/23/2006 71 Female 2/17/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Surgery Other Serious 6/27/2005 Female 2/18/2006 Spain
Primary
Concomitant
Wound Debridement Other Serious 2/1/2003 Male 2/24/2006 United States
Primary
Secondary
Concomitant
Drug Ineffective 80 Female 2/28/2006 Consumer United States
Primary
Secondary
Wound Drainage Other Serious 1/1/2001 52 Male 3/15/2006 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 3/24/2006 United States
Primary
Secondary
Concomitant
Light Chain Analysis Increased Other Serious 82 Female 2/24/2006 Physician United States
Primary
Concomitant
Plastic Surgery Other Serious 2/26/2004 57 Female 141 lb 4/13/2006 Physician South Africa
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 3/1/2006 Male 4/18/2006 Physician Finland
Primary
Concomitant
Osteonecrosis Other Serious 11/17/2005 75 Male 4/20/2006 Physician Spain
Primary
Concomitant
Wound Debridement Other Serious 2/1/2003 Male 5/8/2006 United States
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 4/15/2006 78 Male 160 lb 5/18/2006 Physician China
Primary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 5/31/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 Male 6/1/2006 United States
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 4/15/2006 78 Male 160 lb 5/25/2006 Physician China
Primary
Concomitant
Renal Failure Other Serious 1/1/2000 69 Male 6/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2000 69 Male 6/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2002 70 Female 6/4/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 54 Female 123 lb 5/31/2006 Physician United States
Primary
Concomitant
Soft Tissue Disorder Other Serious 1/1/2005 68 Male 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Streptococcal Infection Hospitalization 6/7/2006 Male 135 lb 6/8/2006 United States
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Life Threatening 4/15/2006 78 Male 160 lb 6/15/2006 Physician China
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2003 61 Male 6/22/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 2/1/2003 61 Male 6/30/2006 United States
Primary
Concomitant
Wound Treatment Other Serious 1/23/2006 71 Female 7/5/2006 Italy
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 66 Male 7/4/2006 Other Health Professional Italy
Primary
Concomitant
Tooth Extraction Other Serious 80 Female 7/5/2006 Other Health Professional Italy
Primary
Concomitant
Tooth Extraction Other Serious 58 Male 7/5/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 80 Female 7/5/2006 Other Health Professional Italy
Primary
Concomitant
Tooth Extraction Other Serious 65 Female 7/5/2006 Other Health Professional Italy
Primary
Concomitant
Osteomyelitis Hospitalization 6/5/2005 72 Male 7/18/2006 Italy
Primary
Concomitant
Osteomyelitis Hospitalization 8/23/2005 79 Female 7/21/2006 Italy
Primary
Concomitant
Surgery Hospitalization 2/28/2006 68 Male 7/24/2006 Other Health Professional Italy
Primary
Concomitant
Tooth Extraction Other Serious 2/1/2003 61 Male 7/25/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2002 62 Male 8/16/2006 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 75 Male 8/17/2006 Other Health Professional United States
Primary
Concomitant
Wound Debridement Other Serious 1/1/1999 56 Male 8/23/2006 Other Health Professional Poland
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2000 55 8/22/2006 Other Health Professional Poland
Primary
Concomitant
Vision Blurred Other Serious 3/5/2002 72 Male 190 lb 9/27/2006 Consumer United States
Primary
Secondary
Concomitant
Plasmacytoma Other Serious 54 Male 9/21/2006 Consumer United States
Primary
Secondary
Vision Blurred Other Serious 3/5/2002 72 Male 190 lb 9/27/2006 Consumer United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 10/1/2003 66 Male 9/28/2006 Other Health Professional United States
Primary
Concomitant
Thrombophlebitis Other Serious 1/1/2005 51 Male 10/3/2006 Consumer United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 5/5/2005 61 Female 10/3/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 73 Male 2/2/2007 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/18/2006 75 Female 2/27/2007 Physician Spain
Primary
Concomitant
Tooth Extraction Disability 2/1/2005 84 Male 3/19/2007 France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/23/2006 78 Male 125 lb 3/23/2007 United States
Primary
Concomitant
Tooth Extraction Other Serious 66 Male 3/25/2007 Other Health Professional United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 4/3/2007 Other Health Professional Czech Republic
Primary
Secondary
Urine Amylase Increased Death 7/1/2006 71 Female 7/13/2007 Physician Spain
Primary
Concomitant
Swelling Other Serious 1/1/2005 60 Female 7/20/2007 United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2005 60 Female 7/20/2007 United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 5/30/2007 Female 31 lb 9/17/2007 Pharmacist
Primary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/15/2007 Consumer Switzerland
Primary
Secondary
Ureaplasma Infection Other Serious 28 Male 10/15/2007 Switzerland
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/17/2007
Primary
Secondary
Concomitant
Ureaplasma Infection Hospitalization 28 Male 10/11/2007 Switzerland
Primary
Secondary
Myelodysplastic Syndrome Death 10/25/2007 Physician Italy
Primary
Secondary
Concomitant
Pneumonia Death 10/25/2007 Physician Italy
Primary
Secondary
Concomitant
Sensory Disturbance Hospitalization 10/7/2007 Female 10/26/2007 Physician Italy
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 75 Male 10/29/2007 Japan
Primary
Secondary
Sensory Disturbance Hospitalization 10/7/2007 Female 10/31/2007 Physician Italy
Primary
Secondary
Concomitant
Sensory Disturbance Hospitalization 10/7/2007 Female 11/7/2007 Physician Italy
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 1/1/2005 68 Male 201 lb 12/11/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/20/2003 77 Female 12/18/2007 Physician United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 56 Male 12/18/2007 United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 12/26/2007 Physician United States
Primary
Secondary
Concomitant
Intestinal Ischaemia Other Serious 3/1/2008 4/10/2008 Physician United States
Primary
Concomitant
Human Herpesvirus 6 Infection Other Serious 11 Female 4/16/2008 Physician Austria
Primary
Secondary
Tooth Extraction Other Serious 3/7/2005 Male 4/18/2008 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 78 Male 4/25/2008 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 12/30/2007 71 Male 8/1/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 2/25/2008 79 Female 8/1/2008 Physician United States
Primary
Concomitant
Fatigue Hospitalization 6/16/2008 Male 8/18/2008 Australia
Primary
Secondary
Tooth Extraction Other Serious 12/1/2004 84 Male 9/18/2008 France
Primary
Secondary
Concomitant
Tremor Hospitalization 6/30/2008 78 Male 9/19/2008 Physician Greece
Primary
Secondary
Concomitant
Tremor Hospitalization 5/20/2008 72 Female 9/19/2008 Physician Greece
Primary
Secondary
Concomitant
Nausea Hospitalization 9/12/2008 Female 107 lb 9/24/2008 Germany
Primary
Secondary
Paraesthesia Hospitalization 1/1/2008 75 Female 10/1/2008 Physician United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 8/24/2008 Female 126 lb 10/6/2008 Belgium
Primary
Secondary
Hypocalcaemia Hospitalization 2/28/2008 Female 132 lb 10/7/2008 Greece
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/5/2008 87 Male 10/10/2008 Physician Germany
Primary
Secondary
Hypophosphataemia Other Serious 11/1/2007 Female 115 lb 10/13/2008 United States
Primary
Secondary
Concomitant
Haemoptysis Other Serious 1/1/2007 Male 10/14/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/21/2008 Female 177 lb 10/20/2008 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/26/2008 65 Male 11/19/2008 Physician Italy
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/26/2008 65 Male 12/12/2008 Physician Italy
Primary
Secondary
Concomitant
Somnolence Death 3/22/2007 Female 12/24/2008 Canada
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/29/2008 Female 12/24/2008 Italy
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/2/2008 Female 106 lb 1/5/2009 Belgium
Primary
Secondary
Infection Hospitalization 11/6/2008 74 Female 234 lb 1/6/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/31/2008 69 Female 143 lb 1/6/2009 Physician United States
Primary
Secondary
Concomitant
Somnolence Life Threatening 7/2/2008 Female 106 lb 1/7/2009 Belgium
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 1/1/2004 4 Female 1/7/2009 Italy
Primary
Secondary
Squamous Cell Carcinoma Death 4/1/2002 6 Male 1/7/2009 Italy
Primary
Secondary
Tooth Abscess Disability 10/1/2004 Female 1/19/2009 United States
Primary
Concomitant
Headache Hospitalization 10/4/2008 71 Female 1/22/2009 Physician Israel
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/5/2009 84 Female 154 lb 1/27/2009 Physician Italy
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/8/2008 Female 146 lb 1/29/2009 France
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 8/20/2008 73 Male 2/2/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/18/2008 Female 2/5/2009 Physician United States
Primary
Concomitant
Sepsis Other Serious 12/9/2007 Female 2/10/2009 Australia
Primary
Secondary
Renal Failure Acute Life Threatening 7/2/2008 Female 106 lb 2/11/2009 Belgium
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/24/2008 78 Male 2/11/2009 Physician Spain
Primary
Secondary
Retrograde Amnesia Other Serious 10/5/2008 Male 2/6/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Hyperuricaemia Other Serious 6/2/2008 Male 204 lb 2/18/2009 United States
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 8/10/2008 Male 2/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 Female 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Infarction Hospitalization 1/19/2009 Male 168 lb 2/24/2009 Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/9/2009 Male 172 lb 3/2/2009 Germany
Primary
Secondary
Somnolence Death 3/22/2007 Female 3/2/2009 Canada
Primary
Secondary
Concomitant
Pneumonia Life Threatening 11/12/2007 Male 138 lb 3/4/2009 Spain
Primary
Secondary
Renal Failure Other Serious 1/27/2009 59 Male 2/25/2009 Other Health Professional Spain
Primary
Concomitant
Atrial Fibrillation Hospitalization 12/2/2008 83 Female 168 lb 3/6/2009 Consumer United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/1998 Male 3/9/2009 Physician United States
Primary
Secondary
Concomitant
Light Chain Disease Other Serious 78 Male 3/9/2009
Primary
Secondary
Concomitant
Dermatitis Exfoliative Other Serious 8/16/2008 77 Male 3/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 2/9/2009 67 Male 3/11/2009 Physician Germany
Primary
Secondary
Spinal Fracture Other Serious 3/3/2009 Male 3/12/2009 Turkey
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 1/19/2009 Male 168 lb 3/13/2009 Germany
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 Female 3/13/2009 Physician United States
Primary
Secondary
Concomitant
Pruritus Hospitalization 78 Male 3/13/2009 Consumer Germany
Primary
Secondary
Febrile Bone Marrow Aplasia Hospitalization 2/26/2009 Male 104 lb 3/16/2009 France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/22/2008 56 Female 3/16/2009 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/22/2008 56 Female 3/16/2009 Physician Germany
Primary
Secondary
Concomitant
Thrombophlebitis Other Serious 1/18/2009 67 Male 3/16/2009 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/1/2009 76 Male 3/16/2009 Physician Italy
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/27/2009 60 Male 163 lb 3/18/2009 Physician Spain
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/6/2005 Male 3/18/2009 Physician United States
Primary
Concomitant
Right Ventricular Dysfunction Other Serious 7/1/2008 77 Male 3/19/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Cholangitis Hospitalization 5/18/2007 Male 152 lb 3/23/2009 Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/25/2008 70 Male 176 lb 3/23/2009 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 2/27/2009 71 Male 153 lb 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Pruritus Hospitalization 78 Male 3/24/2009 Consumer Germany
Primary
Secondary
Concomitant
Scrotal Swelling Other Serious 3/4/2009 72 Male 227 lb 3/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Hospitalization 78 Male 3/25/2009 Consumer Germany
Primary
Secondary
Concomitant
Right Ventricular Dysfunction Other Serious 7/1/2008 77 Male 3/26/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 11/15/2008 Female 181 lb 3/27/2009 Turkey
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious 1/1/2009 79 Male 191 lb 3/31/2009 Consumer United States
Primary
Secondary
Renal Failure Life Threatening 3/1/2009 Male 168 lb 3/31/2009 Spain
Primary
Secondary
Staphylococcal Infection Other Serious 2/1/2009 59 Male 3/26/2009 Other Health Professional Spain
Primary
Concomitant

Drug Data