Melphalan combined with Prednisolone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Red Blood Cell Sedimentation Rate Increased Hospitalization 67 Male 12/30/2005 Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 68 Female 95 lb 1/13/2006 Physician Portugal
Primary
Concomitant
Disseminated Tuberculosis Hospitalization 67 Male 1/10/2006 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Female 2/2/2006 Physician Germany
Primary
Concomitant
Vitamin D Decreased Other Serious 72 Female 2/15/2006 Other Health Professional Australia
Primary
Concomitant
Pain In Jaw Disability 3/1/2005 72 Female 157 lb 3/1/2006 United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 5/1/2005 80 Female 132 lb 4/13/2006 Physician Portugal
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 9/1/2001 75 Male 5/25/2006 Physician Sweden
Primary
Secondary
Concomitant
Melaena Other Serious 60 Female 5/22/2006 Australia
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/1/2004 Male 153 lb 6/24/2006 Physician Germany
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/1/2004 Male 153 lb 8/8/2006 Physician Germany
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 1/1/2006 64 Female 10/17/2006 Japan
Primary
Concomitant
Viral Dna Test Positive Other Serious 1/1/2006 64 Female 11/1/2006 Japan
Primary
Concomitant
Vomiting Other Serious 3 Male 11/6/2006
Primary
Concomitant
X-ray Abnormal Other Serious 5/16/2006 70 Male 108 lb 11/14/2006 Physician Japan
Primary
Concomitant
Tachyarrhythmia Other Serious 5/1/2006 79 Female 170 lb 11/23/2006 Pharmacist Germany
Primary
Secondary
Concomitant
Disease Progression Hospitalization 9/1/2004 64 Male 11/13/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8 Male 12/12/2006 Physician Sweden
Primary
Concomitant
Vomiting Other Serious 3 Male 1/9/2007 Consumer Australia
Primary
Secondary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 5 Female 1/9/2007 Consumer Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 10 Male 1/9/2007 Consumer Australia
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 10/17/2006 NotSpecified 1/19/2007 Other Health Professional Norway
Primary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 1/30/2007 Japan
Primary
Concomitant
Transient Ischaemic Attack Other Serious 10/17/2006 1/29/2007 Physician Germany
Primary
Secondary
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 2/8/2007 Japan
Primary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 2/8/2007 Japan
Primary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 2/19/2007 Physician Japan
Primary
Concomitant
X-ray Abnormal Other Serious 5/16/2006 70 Male 108 lb 3/2/2007 Japan
Primary
Concomitant
Thrombosis Hospitalization 9/1/2003 45 Female 3/9/2007 Physician Japan
Primary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 3/5/2007 Physician Japan
Primary
Concomitant
X-ray Abnormal Other Serious 5/16/2006 70 Male 108 lb 3/15/2007 Japan
Primary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 3/16/2007 Physician Japan
Primary
Concomitant
Drug Resistance Other Serious 67 Female 5/1/2007 Consumer Japan
Primary
Secondary
Concomitant
Drug Resistance Other Serious 54 Male 5/1/2007 Consumer Japan
Primary
Secondary
Concomitant
Drug Resistance Other Serious 55 Male 5/1/2007 Consumer Japan
Primary
Secondary
Concomitant
Drug Resistance Other Serious 78 Male 5/1/2007 Consumer Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 5/3/2007 Physician Cyprus
Primary
Concomitant
Multiple Myeloma Life Threatening 4/4/2004 Male 82 lb 5/3/2007 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 5 Female 5/22/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 3/1/2007 80 Male 5/26/2007 Physician Germany
Primary
Concomitant
Tooth Extraction Other Serious 5/23/2006 78 Male 161 lb 5/26/2007 Physician United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 5/23/2006 78 Male 161 lb 5/26/2007 Physician United Kingdom
Primary
Concomitant
Interstitial Lung Disease Other Serious 9 Female 5/29/2007 Japan
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 9 Female 6/7/2007 Japan
Primary
Secondary
Concomitant
Surgery Hospitalization 11/1/2006 65 Male 6/8/2007 Physician Australia
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 3/1/2007 67 Female 243 lb 6/15/2007 Physician Germany
Primary
Secondary
Concomitant
Primary Sequestrum Other Serious 10/12/2006 78 Male 6/23/2007 Physician Japan
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 6/22/2007 Japan
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 6/22/2007 Japan
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 3/1/2007 67 Female 243 lb 6/26/2007 Physician Germany
Primary
Secondary
Concomitant
Renal Impairment Other Serious 4/1/2005 9 Female 7/6/2007 Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 4/1/2005 9 Female 7/6/2007 Japan
Primary
Secondary
Concomitant
Sinusitis Other Serious 10/12/2006 78 Male 128 lb 7/24/2007 Physician Japan
Primary
Secondary
Concomitant
Sinusitis Other Serious 10/12/2006 78 Male 128 lb 7/28/2007 Physician Japan
Primary
Secondary
Concomitant
Tooth Repair Other Serious 1/1/2001 66 Male 132 lb 9/1/2007 Physician Germany
Primary
Concomitant
Pancreatitis Other Serious 5/30/2007 Female 31 lb 9/17/2007 Pharmacist
Primary
Concomitant
Dementia Other Serious 1/1/2007 55 Male 10/22/2007 Physician Japan
Primary
Secondary
Concomitant
Surgery Hospitalization 11/1/2006 62 Male 10/19/2007 Physician Australia
Primary
Secondary
Concomitant
Dementia Hospitalization 11/1/2006 55 Male 10/29/2007 Physician Japan
Primary
Secondary
Concomitant
Sinusitis Other Serious 10/12/2006 78 Male 128 lb 10/31/2007 Japan
Primary
Secondary
Concomitant
Sinusitis Other Serious 10/12/2006 78 Male 128 lb 11/12/2007 Japan
Primary
Secondary
Concomitant
Dementia Hospitalization 11/1/2006 55 Male 11/19/2007 Physician Japan
Primary
Secondary
Concomitant
Bone Infarction Other Serious 11/21/2007 Physician Japan
Primary
Concomitant
Bone Infarction Other Serious 12/7/2007 Physician Japan
Primary
Concomitant
X-ray Abnormal Other Serious 5/16/2006 70 Male 108 lb 1/29/2008 Japan
Primary
Concomitant
X-ray Abnormal Other Serious 5/16/2006 70 Male 108 lb 2/4/2008 Japan
Primary
Concomitant
Tooth Extraction Other Serious 9/4/2007 60 Male 2/6/2008 Physician Japan
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious Male 2/7/2008 Consumer United Kingdom
Primary
Concomitant
Pancytopenia Other Serious Male 2/7/2008 Consumer United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 10/14/2007 85 Male 146 lb 2/28/2008 Physician Japan
Primary
Concomitant
X-ray Abnormal Other Serious 3/9/2007 71 Male 4/8/2008 Physician Australia
Primary
Concomitant
X-ray Abnormal Other Serious 5/16/2006 70 Male 108 lb 4/8/2008 Japan
Primary
Concomitant
Acute Myocardial Infarction Other Serious Male 4/11/2008 Other Health Professional Greece
Primary
Concomitant
Pancytopenia Other Serious Male 4/11/2008 Other Health Professional Greece
Primary
Concomitant
X-ray Abnormal Other Serious 5/16/2006 70 Male 108 lb 4/22/2008 Japan
Primary
Concomitant
Skin Haemorrhage Other Serious 58 Male 4/24/2008 Russian Federation
Primary
Secondary
Sinusitis Other Serious 10/12/2006 78 Male 128 lb 4/30/2008 Japan
Primary
Secondary
Concomitant
Sinusitis Other Serious 10/12/2006 78 Male 128 lb 5/22/2008 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/29/2006 70 Female 111 lb 5/23/2008 Physician Japan
Primary
Secondary
Tooth Extraction Other Serious 9/4/2007 Male 123 lb 7/2/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/29/2006 70 Female 111 lb 7/3/2008 Physician Japan
Primary
Secondary
Human Herpesvirus 6 Infection Other Serious 7/9/2002 11 Female 9/2/2008 Other Health Professional Austria
Primary
Secondary
Concomitant
Rash Hospitalization 2/7/2008 Female 9/19/2008 Physician Ireland
Primary
Concomitant
Productive Cough Hospitalization 10/22/2008 67 Female 11/19/2008 Physician Austria
Primary
Secondary
Splenectomy Hospitalization 7 Female 11/24/2008
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 4 Female 12/2/2008 Other Health Professional Japan
Primary
Concomitant
Respiratory Disorder Death 43 Female 12/2/2008 Japan
Primary
Concomitant
Neoplasm Other Serious 12/11/2008 Portugal
Primary
Concomitant
Autoimmune Thrombocytopenia Other Serious 2/15/2008 Male 12/11/2008 Physician Denmark
Primary
Concomitant
Vomiting Other Serious 51 Female 12/9/2008 Physician Kazakhstan
Primary
Concomitant
Osteonecrosis Other Serious 12/1/2007 57 Female 12/30/2008 Other Health Professional Japan
Primary
Secondary
Vomiting Other Serious 11/30/2008 51 Female 12/22/2008 Physician Kazakhstan
Primary
Concomitant
Vomiting Other Serious 11/30/2008 51 Female 1/5/2009 Physician Kazakhstan
Primary
Concomitant
Sequestrectomy Hospitalization 6/3/2005 Female 181 lb 1/14/2009 Physician Germany
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 54 Male 1/15/2009 Physician Japan
Primary
Secondary
Osteonecrosis Other Serious 12/1/2007 57 Female 1/16/2009 Other Health Professional Japan
Primary
Secondary
Vomiting Hospitalization 4/24/2008 78 Female 104 lb 1/19/2009 Physician Italy
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 11/1/2007 54 Male 1/20/2009 Physician Japan
Primary
Secondary
Somnolence Other Serious 3/22/2008 78 Female 1/19/2009 Consumer Canada
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 11/17/2007 54 Male 2/2/2009 Physician Japan
Primary
Secondary
Concomitant
Deafness Hospitalization 9/11/2008 Male 2/2/2009 Physician France
Primary
Secondary
Concomitant
Platelet Count Decreased Death 4/14/2008 73 Male 2/6/2009 Physician Japan
Primary
Concomitant
Pancytopenia Hospitalization 74 Female 2/5/2009 United Kingdom
Primary
Secondary
Pancytopenia Hospitalization 74 Female 2/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Pneumonia Hospitalization 3/18/2008 Female 205 lb 2/16/2009 Physician Germany
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 74 Female 2/17/2009 Physician United Kingdom
Primary
Secondary
Pneumonia Hospitalization 3/18/2008 Female 205 lb 3/4/2009 Physician Germany
Primary
Concomitant
Immune System Disorder Other Serious 1/1/2008 43 Female 3/6/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Tibia Fracture Other Serious 8/1/2003 62 Male 3/18/2009 Physician Australia
Primary
Secondary
Concomitant
Soft Tissue Necrosis Other Serious Female 3/16/2009 Pharmacist Germany
Primary
Concomitant
Sudden Death Death 3/23/2009 Male 240 lb 3/27/2009 Russian Federation
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 4/1/2008 Female 161 lb 3/31/2009 Physician Germany
Primary
Concomitant
Immune System Disorder Other Serious 1/1/2008 43 Female 101 lb 4/3/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Immune System Disorder Other Serious 1/1/2008 43 Female 101 lb 4/8/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Sudden Death Death 2/1/2005 Male 240 lb 4/8/2009 Russian Federation
Primary
Secondary
Concomitant
Sepsis Other Serious 6/26/2008 57 Male 137 lb 4/14/2009 Physician Japan
Primary
Concomitant
Pyrexia 60 Male 4/9/2009 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 4/14/2009 Other Health Professional Austria
Primary
Secondary
Concomitant
Toothache Other Serious Male 4/17/2009 Physician Japan
Primary
Secondary
Concomitant
Immune System Disorder Death 1/15/2008 43 Female 101 lb 4/22/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Clostridial Infection Death 67 Female 5/20/2009 Germany
Primary
Secondary
Leukopenia Other Serious 67 Female 5/26/2009 Other Health Professional Germany
Primary
Secondary
Vomiting Life Threatening 2/24/2009 Male 6/16/2009 Physician Australia
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/18/2008 Female 205 lb 6/23/2009 Physician Germany
Primary
Concomitant
Mucosal Inflammation Other Serious 8/1/2006 51 Male 6/26/2009 Physician United Kingdom
Primary
Secondary
Productive Cough Hospitalization 10/22/2008 Female 159 lb 6/29/2009 Physician Austria
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 8/1/2006 51 Male 6/29/2009 Physician United Kingdom
Primary
Secondary
Tooth Extraction Hospitalization 4/1/2008 Female 161 lb 7/15/2009 Physician Germany
Primary
Concomitant
Stem Cell Transplant Other Serious 8/1/2006 51 Male 7/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Stem Cell Transplant Other Serious 8/7/2007 Male 181 lb 7/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 1/1/2006 71 Male 7/28/2009 Other Health Professional Portugal
Primary
Concomitant
Vomiting Other Serious 9/1/2006 52 Male 9/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 9/1/2006 52 Male 9/15/2009 United Kingdom
Primary
Secondary
Concomitant
Graft Versus Host Disease In Lung Other Serious 2/1/2006 45 Female 9/14/2009 United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Death 7/1/2006 64 Male 9/15/2009 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/23/2008 Male 148 lb 9/30/2009 Sweden
Primary
Secondary
Concomitant
Platelet Count Decreased Death 4/11/2008 73 Male 10/5/2009 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/23/2008 Male 148 lb 10/8/2009 Physician Sweden
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/5/2009 69 Male 154 lb 10/15/2009 Physician Germany
Primary
Concomitant
Venous Thrombosis Other Serious 1/1/2006 Male 10/21/2009 Other Health Professional Portugal
Primary
Concomitant
Sepsis Death 9/29/2009 Male 137 lb 10/26/2009 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/5/2009 69 Male 154 lb 10/22/2009 Physician Germany
Primary
Concomitant
Septic Shock Death 8/29/2009 Male 10/28/2009 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 9/15/2009 80 Female 190 lb 11/2/2009 Physician Germany
Primary
Secondary
Thrombotic Microangiopathy Other Serious 58 Male 10/27/2009 Physician Japan
Primary
Concomitant
Ureteric Obstruction Life Threatening 10/5/2009 69 Male 154 lb 10/31/2009 Physician Germany
Primary
Concomitant
Transplant Rejection Death 47 Female 11/2/2009 Physician United States
Primary
Secondary
Concomitant
Tenderness Other Serious 2/1/2007 Male 112 lb 11/12/2009 Physician Japan
Primary
Concomitant
Septic Shock Death 9/29/2009 Male 137 lb 12/7/2009 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/25/2009 12/8/2009 Physician Italy
Primary
Concomitant

Drug Data