Melphalan combined with Omeprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Swollen Tongue Other Serious 6/14/2005 Female 163 lb 1/13/2006 Physician Belgium
Primary
Concomitant
Rash Hospitalization 1/12/2006 Female 117 lb 2/15/2006 Physician Portugal
Primary
Concomitant
Osteonecrosis Other Serious 5/1/2005 80 Female 132 lb 4/13/2006 Physician Portugal
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/22/2006 60 Male 7/13/2006 Physician France
Primary
Concomitant
Capillary Leak Syndrome Hospitalization 5/10/2006 Male 7/31/2006 Physician Spain
Primary
Secondary
Concomitant
Vomiting Other Serious 3/18/2006 Female 110 lb 8/11/2006 Physician Belgium
Primary
Secondary
Concomitant
Capillary Leak Syndrome Hospitalization 5/10/2006 Male 9/22/2006 Physician Spain
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/22/2006 60 Male 9/25/2006 Physician France
Primary
Concomitant
Cardiac Failure Hospitalization 5/10/2006 Male 10/9/2006 Physician Spain
Primary
Secondary
Concomitant
Tachyarrhythmia Other Serious 5/1/2006 79 Female 170 lb 11/23/2006 Pharmacist Germany
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 10/30/2006 Male 181 lb 12/4/2006 Physician Czech Republic
Primary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 5 Female 1/9/2007 Consumer Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 10 Male 1/9/2007 Consumer Australia
Primary
Secondary
Concomitant
Stenotrophomonas Infection Other Serious 3 Male 1/9/2007 Consumer Australia
Primary
Secondary
Concomitant
Sepsis Hospitalization 3 Male 5/17/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 5 Female 5/22/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/1/2007 81 Female 6/18/2007 Consumer France
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/9/2006 67 Female 8/10/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/10/2006 59 Female 181 lb 8/21/2007 Other Health Professional Belgium
Primary
Concomitant
Deafness Disability 4/3/2007 Male 206 lb 1/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 3/3/2008 Female 3/20/2008 Physician Belgium
Primary
Concomitant
Thrombocytopenia Other Serious 1/16/2008 Female 112 lb 4/30/2008 Physician France
Primary
Concomitant
Rash Other Serious 5/15/2008 Male 5/21/2008 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 3/3/2008 Female 148 lb 5/28/2008 Physician Belgium
Primary
Concomitant
Sepsis Other Serious 3/3/2008 Female 148 lb 7/10/2008 Physician Belgium
Primary
Concomitant
Pyrexia Hospitalization 6/30/2008 45 Male 163 lb 7/16/2008 Physician Spain
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/30/2008 45 Male 163 lb 7/22/2008 Physician Spain
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 7/27/2008 Male 128 lb 8/28/2008 Poland
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/29/2008 Female 9/8/2008 Italy
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 4/22/2008 57 Male 223 lb 9/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/18/2008 Male 9/10/2008 Italy
Primary
Secondary
Concomitant
Rash Hospitalization 6/30/2008 45 Male 163 lb 9/17/2008 Physician Spain
Primary
Secondary
Concomitant
Sudden Death Other Serious 10/1/2008 Italy
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/1/2008 58 Male 123 lb 10/16/2008 Physician Spain
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/1/2008 58 Male 123 lb 10/17/2008 Physician Spain
Primary
Secondary
Concomitant
Tachycardia Other Serious 8/1/2008 Male 10/22/2008 Other Health Professional Spain
Primary
Concomitant
Deafness Disability 4/3/2007 Male 206 lb 11/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/29/2008 Female 12/24/2008 Italy
Primary
Secondary
Concomitant
Pancreatitis Other Serious 1/16/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Headache Hospitalization 10/4/2008 71 Female 1/22/2009 Physician Israel
Primary
Secondary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 2/11/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/18/2008 58 Male 132 lb 3/3/2009 Physician Spain
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/18/2008 58 Male 132 lb 3/5/2009 Physician Spain
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/7/2008 38 Female 139 lb 3/9/2009 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 8/18/2008 58 Male 3/6/2009 Other Health Professional Spain
Primary
Concomitant
Nodal Arrhythmia Life Threatening 2/24/2009 Male 128 lb 4/10/2009 Australia
Primary
Secondary
Concomitant
Interacting
Thrombocytopenia Hospitalization 2/11/2009 Female 4/15/2009 Physician Greece
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/11/2009 Female 132 lb 5/14/2009 Physician Greece
Primary
Secondary
Concomitant
Nodal Arrhythmia Life Threatening 2/24/2009 Male 128 lb 6/9/2009 Australia
Primary
Secondary
Concomitant
Interacting
Pancreatitis Other Serious 5 Female 6/10/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/24/2009 Male 6/16/2009 Physician Australia
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 5/9/2009 41 Male 165 lb 7/1/2009 Physician Spain
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 6/11/2009 Female 141 lb 7/1/2009 Canada
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 3/29/2009 79 Female 115 lb 7/13/2009 Physician Belgium
Primary
Concomitant
Pulmonary Oedema Hospitalization 6/11/2009 Female 141 lb 7/24/2009 Canada
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 8/27/2009 58 Male 9/28/2009 Physician Spain
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/4/2007 Male 106 lb 10/7/2009 Poland
Primary
Secondary
Concomitant
Pyrexia Other Serious 61 Female 132 lb 10/19/2009 Physician France
Primary
Concomitant
Ventricular Fibrillation Hospitalization 11/9/2009 Male 176 lb 11/24/2009 Netherlands
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/2/2002 Female 125 lb 11/25/2009 United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 11/10/2009 70 Female 11/24/2009 Physician Spain
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/2/2002 Female 125 lb 12/16/2009 United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 11/24/2009 12/30/2009 Physician Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 11/9/2009 Male 176 lb 1/5/2010 Netherlands
Primary
Secondary
Concomitant
Walking Aid User Other Serious 10/23/2003 Male 2/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 11/9/2009 Male 176 lb 3/3/2010 Netherlands
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 1/10/2010 Male 3/8/2010 Physician Australia
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 4/15/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 7/14/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 61 Male 245 lb 7/19/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 7/19/2010 United States
Primary
Secondary
Concomitant
Nodal Arrhythmia Life Threatening 2/24/2009 71 Male 128 lb 7/22/2010 Physician Australia
Primary
Secondary
Concomitant
Interacting
Weight Decreased Other Serious 4/1/2006 54 Male 7/29/2010 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 11/9/2009 75 Male 176 lb 8/4/2010 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/1/2009 55 Male 186 lb 8/6/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 8/6/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 61 Male 245 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 3/11/2009 23 Female 97 lb 8/17/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 5/1/2009 8/18/2010 Physician France
Primary
Concomitant
Pyrexia Other Serious 5/12/2010 62 Female 110 lb 8/18/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 8/23/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 8/26/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 8/26/2010 United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 6/4/2010 63 Female 131 lb 8/27/2010 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 3/11/2009 23 Female 97 lb 8/31/2010 Physician Japan
Primary
Concomitant
Transaminases Increased Other Serious 5/1/2009 9/3/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Cataract Hospitalization 5/24/2010 67 Male 190 lb 9/7/2010 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 46 Male 9/10/2010 Consumer Czech Republic
Primary
Concomitant
Syncope Other Serious 10/1/2010 47 Male 12/20/2010 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 12/20/2010 United States
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 12/23/2010 United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 9/21/2010 72 Male 12/30/2010 Italy
Primary
Secondary
Concomitant
Carcinoid Tumour Of The Duodenum Hospitalization 10/25/2010 68 Male 148 lb 1/7/2011 Physician Netherlands
Primary
Secondary
Concomitant
Multiple Myeloma Death 10/11/2010 80 Male 210 lb 1/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Death 10/6/2010 47 Male 1/17/2011 Physician United States
Primary
Concomitant
Weight Increased Other Serious 6/20/2010 1/20/2011 Physician France
Primary
Secondary
Concomitant
Rash Generalised Death 10/23/2010 90 Male 1/26/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/23/2010 69 Male 174 lb 2/4/2011 Physician Belgium
Primary
Secondary
Concomitant
Carcinoid Tumour Of The Duodenum Hospitalization 10/25/2010 68 Male 148 lb 2/7/2011 Physician Netherlands
Primary
Secondary
Concomitant
Syncope Other Serious 12/7/2010 47 Male 2/7/2011 Physician United States
Primary
Concomitant
Febrile Neutropenia Death 10/23/2010 90 Male 2/15/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Lung Disorder Other Serious 9/21/2010 72 Male 2/18/2011 Italy
Primary
Secondary
Concomitant
Hypomagnesaemia Other Serious 1/1/1995 57 Male 3/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Pyrexia Death 8/29/2008 60 Female 3/29/2011 Physician Italy
Primary
Secondary
Concomitant
Pain In Jaw Disability 3/11/2002 65 Female 4/8/2011 Other Health Professional United States
Primary
Concomitant
Osteomalacia Disability 3/11/2002 65 Female 4/19/2011 Physician United States
Primary
Concomitant
Cerebral Ischaemia Hospitalization 10/4/2008 71 Female 4/20/2011 Consumer Israel
Primary
Secondary
Concomitant
Anaemia Death 1/2/2011 4/22/2011 Consumer United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 8/31/2007 72 Female 110 lb 4/26/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Platelet Count Decreased Death 8/29/2010 74 Male 4/27/2011 Physician United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 10/11/2010 80 Male 210 lb 4/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Other Serious 10/9/2007 70 Male 181 lb 4/28/2011 Consumer Poland
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Intestine Hospitalization 4/9/2011 42 Female 197 lb 4/28/2011 Consumer United States
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Hospitalization 2/17/2011 73 Male 205 lb 4/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bundle Branch Block Right Other Serious 3/11/2002 65 Female 5/3/2011 United States
Primary
Concomitant
Pain Hospitalization 4/21/2011 5/5/2011 Physician Italy
Primary
Secondary
Concomitant
Multiple Myeloma Death 1/1/2010 64 Male 5/6/2011 Pharmacist United States
Primary
Concomitant
Spinal Claudication Hospitalization 3/11/2002 65 Female 8/31/2011 Other Health Professional United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 6/1/2007 9/15/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebral Toxoplasmosis Life Threatening 10/1/2010 59 Female 82 lb 2/21/2012 Physician Japan
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 2/2/2012 71 Female 190 lb 2/23/2012 Physician Spain
Primary
Secondary
Concomitant
Syncope Other Serious 2/2/2012 2/27/2012 Physician Spain
Primary
Concomitant
Malignant Melanoma In Situ Other Serious 1/16/2012 64 Male 192 lb 2/28/2012 Physician Germany
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 12/15/2010 52 Male 150 lb 2/29/2012 Physician Japan
Primary
Concomitant
Small Intestine Carcinoma Hospitalization 10/25/2010 68 Male 148 lb 5/23/2012 Physician Netherlands
Primary
Secondary
Concomitant
Cerumen Impaction Other Serious Male 132 lb 5/24/2012 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 3/11/2009 23 Female 97 lb 3/21/2013 Physician Jp
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/23/2010 62 Male 150 lb 2/5/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Interacting
Malignant Melanoma Death 8/26/2008 78 Male 210 lb 11/16/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/19/2011 90 Male 172 lb 11/6/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Neutropenic Sepsis Life Threatening 12/15/2010 78 Male 147 lb 2/13/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Neutropenic Sepsis Life Threatening 12/15/2010 78 Male 147 lb 2/22/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/2011 Male 12/14/2012 Consumer Br
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 2/19/2011 25 Male 123 lb 9/18/2012 Physician Jp
Primary
Concomitant
Malignant Melanoma In Situ Other Serious 1/16/2012 64 Male 192 lb 8/28/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Respiratory Failure Death 4/11/2012 74 Male 9/14/2012 Pharmacist Us
Primary
Concomitant
Breast Cancer Hospitalization 2/21/2012 77 Female 139 lb 3/11/2013 Physician Nl
Primary
Secondary
Concomitant
Plasmacytoma Other Serious 7/10/2012 87 Male 118 lb 9/7/2012 Physician Gb
Primary
Secondary
Concomitant
Plasmacytoma Other Serious 7/10/2012 87 Male 118 lb 10/9/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/8/2012 53 Female 146 lb 10/2/2012 Physician Mx
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 70 10/30/2012 Consumer Au
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 9/17/2012 80 Male 179 lb 11/12/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Hospitalization 2012 Male 12/12/2012 Physician Us
Primary
Concomitant
Death Death 11/15/2012 11/30/2012 Pharmacist Ie
Primary
Concomitant
Ocular Icterus Hospitalization 65 Male 12/19/2012 Country Not Specified
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/18/2010 47 Female 12/17/2012 Physician Cz
Primary
Secondary
Concomitant
Vomiting Death 7/30/2012 54 Female 123 lb 3/18/2013 Physician Jp
Primary
Secondary
Concomitant
Vomiting Disability 3/11/2002 66 Female 11/22/2012 Consumer Us
Primary
Concomitant
Oesophageal Squamous Cell Carcinoma Death 12/23/2010 75 Male 190 lb 1/30/2013 Physician Us
Primary
Secondary
Concomitant
Wheezing Other Serious 2/2006 Male 12/27/2012 Other Health Professional Us
Primary
Secondary
Concomitant

Drug Data