Melphalan Hydrochloride combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neutropenia Other Serious 11/4/2008 Female 97 lb 6/22/2009 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 Male 6/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 9/2/2009 Physician United States
Primary
Secondary
Concomitant
Swelling Other Serious 8/19/2009 71 Female 9/7/2009 Physician Japan
Primary
Concomitant
Septic Shock Life Threatening 6/28/2009 Male 148 lb 9/9/2009 France
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/14/2004 Male 1/12/2010 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/2/2002 Female 125 lb 1/13/2010 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 12/21/2009 Female 104 lb 1/14/2010 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2005 Male 136 lb 1/15/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2002 Female 195 lb 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 1/15/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/6/2005 Male 1/21/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 1/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/30/2001 Female 115 lb 1/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 11/1/2005 Female 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2002 Male 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 10/23/2003 Male 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Lesion Hospitalization 10/29/2009 63 Female 1/25/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Male 245 lb 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Respiratory Failure Death 11/26/2009 1/29/2010 Physician Spain
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 11/3/2006 Male 1/30/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 2/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/1/2006 Male 2/4/2010 Physician South Africa
Primary
Concomitant
Weight Decreased Other Serious 2/1/2003 Male 2/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/13/2010 85 Female 207 lb 2/9/2010 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 4/15/2005 Male 195 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 10/11/2004 Female 195 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 2/9/2010 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/1/2006 Male 2/11/2010 Physician South Africa
Primary
Concomitant
Tooth Extraction Other Serious 10/20/1999 Male 178 lb 2/11/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2000 Male 2/11/2010 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2007 Male 170 lb 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2000 Female 140 lb 2/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 Male 161 lb 2/12/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Male 245 lb 2/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/9/2002 Male 136 lb 2/15/2010 Physician United States
Primary
Concomitant
Neurotoxicity Disability 12/1/2008 Female 2/16/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2002 Female 195 lb 2/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 11/3/2006 Male 169 lb 2/16/2010 Other Health Professional United States
Primary
Concomitant
Toothache Other Serious 7/1/2005 Female 2/16/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 Male 2/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/15/2005 Male 209 lb 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/20/1999 Male 178 lb 3/11/2010 Consumer United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2007 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Male 245 lb 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 Female 125 lb 3/17/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/23/2001 Male 161 lb 3/17/2010 Physician United States
Primary
Secondary
Concomitant
Spinal Corpectomy Other Serious 7/30/2004 Male 3/18/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/18/2010 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 9/13/2006 Male 169 lb 3/19/2010 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2004 Female 195 lb 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2007 Male 170 lb 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/14/2007 Male 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2000 Male 3/22/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 Female 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2007 3/24/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/30/2001 Female 115 lb 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/1/2002 Male 178 lb 3/25/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2002 Female 195 lb 3/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Male 245 lb 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/23/2001 Male 161 lb 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 Male 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/15/2005 Male 209 lb 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 Male 3/26/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 5/1/2000 Female 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Hesitation Other Serious 1/14/2007 Male 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Male 245 lb 3/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/2000 Female 140 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 Female 125 lb 3/30/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/30/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 Female 195 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2007 3/31/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/22/2008 64 Male 4/5/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 56 Female 195 lb 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 4/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 48 Male 4/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/23/2001 44 Male 161 lb 4/8/2010 Physician United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 4/9/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/12/2005 60 Male 136 lb 4/9/2010 Other Health Professional United States
Primary
Concomitant
Toothache Other Serious 7/1/2005 62 Female 4/12/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2005 61 Male 245 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2004 64 Female 195 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 4/14/2010 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 9/13/2006 68 Male 169 lb 4/15/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 3/14/1999 48 Male 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 5/1/2000 75 Female 4/16/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 4/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venous Insufficiency Other Serious 2/1/1998 60 Male 4/19/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 56 Male 4/19/2010 United States
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 1/1/2007 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Neurotoxicity Disability 12/1/2008 77 Female 4/22/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2003 56 Male 4/22/2010 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2005 61 Male 245 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 9/13/2006 68 Male 169 lb 4/27/2010 Other Health Professional United States
Primary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 4/28/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 4/29/2010 United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 5/4/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/15/2005 50 Male 209 lb 5/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 48 Male 5/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venous Insufficiency Other Serious 2/1/1998 60 Male 5/7/2010 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/23/2010 5/10/2010 Physician Spain
Primary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 5/10/2010 United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 1/1/2007 65 Male 170 lb 5/12/2010 United States
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 5/12/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2002 56 Female 195 lb 5/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 44 Male 5/12/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 5/1/2000 75 Female 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 2/6/2003 66 Female 5/13/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2002 58 Female 115 lb 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venous Insufficiency Other Serious 2/1/1998 60 Male 5/21/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 6/1/2002 39 Male 173 lb 5/24/2010 United States
Primary
Concomitant
General Physical Health Deterioration Other Serious 3/29/2010 73 Male 150 lb 5/24/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Vision Blurred Other Serious 2/1/1998 60 Male 5/25/2010 United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 4/1/2010 81 Male 5/25/2010 Physician Tunisia
Primary
Concomitant
Toothache Other Serious 7/1/2005 62 Female 5/26/2010 Physician United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 5/26/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 5/28/2010 United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 6/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2004 64 Female 195 lb 6/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/11/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2002 58 Female 115 lb 6/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 3/29/2010 73 Male 151 lb 6/14/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 6/1/2009 72 Female 132 lb 6/15/2010 Physician Spain
Primary
Concomitant
Paraesthesia Disability 4/9/2009 78 Female 6/15/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 6/21/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 61 Male 245 lb 6/21/2010 United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 6/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Mobility Decreased Hospitalization 3/29/2010 73 Male 6/22/2010 Physician Switzerland
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/22/2010 United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious Male 140 lb 6/23/2010 Other Health Professional United States
Primary
Concomitant
General Physical Health Deterioration Other Serious 3/29/2010 73 Male 151 lb 6/24/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Vomiting Other Serious 11/25/1998 43 Female 170 lb 6/25/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/25/1998 43 Female 170 lb 6/29/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 61 Male 245 lb 6/29/2010 United States
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/30/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/25/1998 43 Female 170 lb 7/5/2010 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 7/5/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/25/2005 50 Male 209 lb 7/5/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/25/1998 43 Female 170 lb 7/7/2010 United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 3/29/2010 73 Male 151 lb 7/8/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/20/2003 93 Female 126 lb 7/8/2010 United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 7/8/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/2000 52 Female 140 lb 7/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 12/1/2008 47 9/16/2010 Other Health Professional Italy
Primary
Concomitant

Drug Data