Melphalan Hydrochloride combined with Thalidomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Constipation Hospitalization 79 Female 6/10/2009 Other Health Professional Denmark
Primary
Concomitant
Sinoatrial Block Hospitalization 5/11/2009 Male 185 lb 6/17/2009 France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/20/2003 Female 6/17/2009 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 12/1/2008 92 Male 6/23/2009 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/8/2009 Female 238 lb 6/24/2009 Physician Spain
Primary
Secondary
Weight Decreased Other Serious 2/1/2003 Male 6/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 6/26/2009 Female 112 lb 8/7/2009 Turkey
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 7/10/2009 Male 251 lb 8/7/2009 France
Primary
Secondary
Concomitant
Stem Cell Transplant Life Threatening 6/2/2009 61 Female 132 lb 8/3/2009 Physician France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/28/2009 78 Female 172 lb 8/3/2009 Physician Italy
Primary
Secondary
Tumour Lysis Syndrome Other Serious 1/26/2009 64 Male 121 lb 8/6/2009 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/26/2009 Female 121 lb 8/12/2009 Turkey
Primary
Secondary
Gamma-glutamyltransferase Increased Hospitalization 7/10/2009 Male 251 lb 8/17/2009 France
Primary
Secondary
Concomitant
Stem Cell Transplant Life Threatening 6/2/2009 61 Female 143 lb 8/12/2009 Physician France
Primary
Secondary
Concomitant
Tremor Hospitalization 6/1/2008 77 Male 8/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/8/2009 Female 238 lb 8/20/2009 Physician Spain
Primary
Secondary
Concomitant
Syncope Hospitalization 6/27/2009 Male 8/24/2009 Physician Austria
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/10/2009 Male 251 lb 8/24/2009 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/1/2003 Male 108 lb 8/26/2009 Physician Japan
Primary
Secondary
Concomitant
Delirium Hospitalization 8/18/2009 Female 196 lb 8/28/2009 Netherlands
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/20/2003 Female 9/1/2009 Physician United States
Primary
Secondary
Concomitant
Brain Stem Infarction Hospitalization 7/31/2009 Male 121 lb 9/3/2009 France
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 8/31/2009 Female 112 lb 9/8/2009 Italy
Primary
Secondary
Concomitant
Tooth Extraction Other Serious Male 9/8/2009 Other Health Professional United States
Primary
Concomitant
Septic Shock Life Threatening 6/28/2009 Male 148 lb 9/9/2009 France
Primary
Secondary
Concomitant
Sternal Fracture Hospitalization 8/31/2009 Female 112 lb 9/11/2009 Italy
Primary
Secondary
Concomitant
Delirium Hospitalization 8/18/2009 Female 196 lb 9/14/2009 Netherlands
Primary
Secondary
Concomitant
Syncope Hospitalization 6/27/2009 Male 10/21/2009 Physician Austria
Primary
Secondary
Concomitant
Tumour Flare Hospitalization 8/6/2009 Female 127 lb 11/6/2009 Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 12/17/2006 72 Male 90 lb 12/23/2009 Physician Taiwan, Province Of China
Primary
Secondary
Tooth Extraction Other Serious 1/14/2004 Male 1/12/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 12/21/2009 Female 104 lb 1/14/2010 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2005 Male 136 lb 1/15/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2002 Female 195 lb 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Myeloma Hospitalization 12/7/2009 Female 111 lb 1/19/2010 France
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/6/2005 Male 1/21/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 1/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 11/1/2005 Female 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2002 Male 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 10/23/2003 Male 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Life Threatening 6/2/2009 Female 143 lb 1/26/2010 France
Primary
Secondary
Concomitant
Hepatocellular Injury 12/10/2009 83 Male 151 lb 1/22/2010 Pharmacist United States
Primary
Secondary
Pleural Effusion Hospitalization 1/29/2010 Physician Japan
Primary
Concomitant
Parkinson's Disease Hospitalization 10/13/2009 Female 117 lb 1/29/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Tooth Extraction Other Serious Male 1/30/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 2/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Infection Hospitalization 1/9/2010 Male 2/4/2010 Physician France
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Life Threatening 6/2/2009 61 Female 143 lb 1/27/2010 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 Male 2/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Retro-orbital Neoplasm Hospitalization 1/22/2010 Male 155 lb 2/5/2010 France
Primary
Secondary
Concomitant
Cataract Hospitalization 6/25/2009 Male 190 lb 2/8/2010 France
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 11/9/2009 Male 176 lb 2/8/2010 Netherlands
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 4/15/2005 Male 195 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 10/11/2004 Female 195 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 2/1/2005 Male 240 lb 2/11/2010 Russian Federation
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/20/1999 Male 178 lb 2/11/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/20/2003 Female 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2005 39 Male 2/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2000 Female 140 lb 2/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/22/2005 Female 181 lb 2/15/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 4/9/2002 Male 136 lb 2/15/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2002 Female 195 lb 2/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Hospitalization 9/28/2009 Female 87 lb 2/16/2010 France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 Male 2/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 7/19/2009 74 Female 2/10/2010 Other Health Professional China
Primary
Concomitant
Cataract Operation Hospitalization 6/25/2009 Male 190 lb 2/19/2010 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/15/2005 Male 209 lb 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 8/28/2009 74 Male 3/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 11/17/2009 80 Male 192 lb 3/9/2010 Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 9/28/2009 Female 87 lb 3/9/2010 France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/11/2010 Other Health Professional Greece
Primary
Secondary
Tooth Extraction Other Serious 10/20/1999 Male 178 lb 3/11/2010 Consumer United States
Primary
Secondary
Concomitant
Sudden Death Death 3/23/2009 Male 240 lb 3/12/2010 Russian Federation
Primary
Secondary
Concomitant
Urine Analysis Abnormal Hospitalization 1/9/2010 Male 3/12/2010 Physician France
Primary
Secondary
Concomitant
Vitamin B12 Increased Other Serious 74 Male 3/6/2010 United Kingdom
Primary
Secondary
Concomitant
Retro-orbital Neoplasm Hospitalization 1/22/2010 Male 155 lb 3/17/2010 France
Primary
Secondary
Concomitant
Spinal Corpectomy Other Serious 7/30/2004 Male 3/18/2010 Physician United States
Primary
Concomitant
Ulcer Other Serious 1/1/2002 Male 3/18/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/18/2010 Physician United States
Primary
Concomitant
Paraproteinaemia Other Serious 8/28/2009 74 Male 3/18/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2004 Female 195 lb 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 8/28/2009 74 Male 3/15/2010 Physician United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/14/2007 Male 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/20/2003 Female 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 Female 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 3/8/2010 Female 159 lb 3/23/2010 Belgium
Primary
Secondary
Concomitant
Vomiting Other Serious 7/30/2001 Female 115 lb 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/22/2005 Female 181 lb 3/24/2010 United States
Primary
Concomitant
Tooth Extraction Other Serious 12/1/2002 Male 178 lb 3/25/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2002 Female 195 lb 3/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/5/2002 Female 3/25/2010 Physician United States
Primary
Secondary
Concomitant
Paraproteinaemia Other Serious 74 Male 3/20/2010 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/15/2005 Male 209 lb 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 Male 3/26/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 5/1/2000 Female 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Hesitation Other Serious 1/14/2007 Male 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/2000 Female 140 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/30/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 Female 195 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2007 3/31/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 3/8/2010 75 Female 159 lb 4/1/2010 Belgium
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/5/2002 76 Female 4/1/2010 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 1/10/2010 76 Male 4/5/2010 Physician Australia
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2002 56 Female 195 lb 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 4/7/2010 Italy
Primary
Secondary
Weight Decreased Other Serious 11/1/2001 50 Female 4/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/2/2000 Female 4/7/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 4/7/2010 Consumer United States
Primary
Secondary
Hypophosphataemia Other Serious 3/11/2010 61 Male 4/7/2010 Physician United States
Primary
Secondary
Multi-organ Failure Death 73 Male 4/9/2010 Israel
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/22/2005 80 Female 181 lb 4/9/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 60 Male 136 lb 4/9/2010 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2004 64 Female 195 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 4/14/2010 United States
Primary
Secondary
Concomitant
Tremor Other Serious 4/14/2010 Italy
Primary
Secondary
Visual Impairment Other Serious 7/12/1999 63 Female 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 4/15/2010 Italy
Primary
Secondary
Concomitant
Hypophosphataemia Other Serious 3/11/2010 61 Male 4/15/2010 Physician United States
Primary
Secondary
Wound Drainage Other Serious 5/1/2000 75 Female 4/16/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 4/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 56 Male 4/19/2010 United States
Primary
Secondary
Concomitant
Vertebroplasty Other Serious 4/19/2001 81 Male 165 lb 4/19/2010 United States
Primary
Concomitant
Tooth Abscess Other Serious 1/1/2007 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Vertebroplasty Other Serious 4/19/2001 81 Male 165 lb 4/21/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2003 56 Male 4/22/2010 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/11/2010 76 Male 4/28/2010 Netherlands
Primary
Concomitant
Multi-organ Failure Death 73 Male 4/29/2010 Israel
Primary
Concomitant
International Normalised Ratio Other Serious 3/29/2010 73 Male 150 lb 4/29/2010 Switzerland
Primary
Secondary
International Normalised Ratio Other Serious 3/29/2010 73 Male 150 lb 4/30/2010 Switzerland
Primary
Secondary
Tooth Disorder Other Serious 1/1/2002 Male 5/4/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/15/2005 50 Male 209 lb 5/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 65 Male 5/5/2010
Primary
Secondary
Hypophosphataemia Other Serious 3/11/2010 61 Male 5/6/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/5/2002 76 Female 5/7/2010 United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 5/10/2010 Physician Poland
Primary
Secondary
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 5/12/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2002 56 Female 195 lb 5/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/2/2000 Female 5/12/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 44 Male 5/12/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 5/1/2000 75 Female 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 2/6/2003 66 Female 5/13/2010 United States
Primary
Secondary
Concomitant
Pneumonia Death Unknown 5/10/2010 France
Primary
Secondary
Peritonitis Death 5/3/2010 72 Female 5/14/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pneumonia Bacterial Death 5/10/2010 France
Primary
Secondary
Pancreatitis Death 5/10/2010 France
Primary
Secondary

Drug Data