Melphalan Hydrochloride combined with Revlimid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pruritus Hospitalization 5/18/2007 79 Male 152 lb 6/17/2009 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Death 6/10/2009 Female 154 lb 6/18/2009 Belarus
Primary
Secondary
Concomitant
Neutropenia Other Serious 11/4/2008 Female 97 lb 6/22/2009 Physician France
Primary
Secondary
Concomitant
Vulval Cellulitis Other Serious 9/3/2008 82 Female 6/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Death 6/10/2009 Female 154 lb 8/10/2009 Belarus
Primary
Secondary
Concomitant
Laryngeal Oedema Hospitalization 5/4/2009 Female 145 lb 8/19/2009 United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 5/10/2009 77 Male 8/20/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 5/4/2009 78 Female 8/26/2009 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/22/2009 Male 210 lb 8/26/2009 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/4/2007 Male 106 lb 8/26/2009 Poland
Primary
Secondary
Concomitant
Renal Failure Life Threatening 3/10/2009 Male 168 lb 8/26/2009 Spain
Primary
Secondary
Nausea Other Serious 7/20/2009 Female 119 lb 8/26/2009 United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/9/2007 Male 181 lb 9/2/2009 Poland
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 9/5/2008 Male 139 lb 9/2/2009 Greece
Primary
Secondary
Septic Shock Death 2/4/2008 Male 165 lb 9/2/2009 Greece
Primary
Secondary
Pseudomembranous Colitis Hospitalization 3/25/2008 Male 121 lb 9/8/2009 Czech Republic
Primary
Secondary
Sepsis Hospitalization 1/3/2009 Male 167 lb 9/8/2009 Germany
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 76 Female 9/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/4/2007 Male 106 lb 9/10/2009 Poland
Primary
Secondary
Concomitant
Face Oedema Hospitalization 4/23/2007 Female 110 lb 9/15/2009 Italy
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/2/2002 Female 125 lb 1/13/2010 United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/6/2005 Male 1/21/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 1/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2002 Male 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Lesion Hospitalization 10/29/2009 63 Female 1/25/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 2/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 5/1/2008 Male 172 lb 2/4/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 Male 161 lb 2/12/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/15/2005 Male 209 lb 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/11/2010 Other Health Professional Greece
Primary
Secondary
Wound Drainage Other Serious 7/1/2007 Female 125 lb 3/17/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/23/2001 Male 161 lb 3/17/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/22/2010 Female 3/17/2010 Italy
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/14/2007 Male 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tachyarrhythmia Life Threatening 10/2/2009 Male 139 lb 3/23/2010 Physician France
Primary
Secondary
Concomitant
Septic Shock Death 2/16/2009 Male 3/24/2010 Spain
Primary
Secondary
Weight Decreased Other Serious 1/23/2001 Male 161 lb 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/15/2005 Male 209 lb 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Hesitation Other Serious 1/14/2007 Male 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 Female 125 lb 3/30/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/16/2010 78 Female 4/1/2010 Italy
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 4/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/23/2001 44 Male 161 lb 4/8/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 1/20/2010 70 Male 4/8/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 4/14/2010 United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 4/15/2010 Italy
Primary
Secondary
Concomitant
Multiple Myeloma Death 1/1/2010 60 Female 4/15/2010 Other Health Professional Israel
Primary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 4/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 4/9/2010 66 Male 148 lb 4/23/2010 United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 4/9/2010 66 Male 145 lb 4/28/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 4/29/2010 United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 5/4/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/15/2005 50 Male 209 lb 5/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Endometrial Sarcoma Other Serious 1/1/2007 60 Female 5/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Hospitalization 4/9/2010 66 Male 145 lb 5/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 44 Male 5/12/2010 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 4/26/2010 86 Male 168 lb 5/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 5/28/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/2/2010 Italy
Primary
Secondary
Flatulence Other Serious 2/18/2010 77 Male 6/8/2010 Physician United States
Primary
Concomitant
Skin Ulcer Other Serious 1/1/2010 78 Male 6/10/2010 Physician United States
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/11/2010 United States
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Other Serious 1/1/2010 87 Male 168 lb 6/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2008 56 Male 6/15/2010 Austria
Primary
Concomitant
Torsade De Pointes Other Serious 6/1/2009 72 Female 132 lb 6/15/2010 Physician Spain
Primary
Concomitant
Thrombocytopenia Other Serious 6/15/2010 Consumer United States
Primary
Secondary
Weight Decreased Other Serious 4/1/2006 54 Male 6/21/2010 United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 6/22/2010 Italy
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/22/2010 United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious Male 140 lb 6/23/2010 Other Health Professional United States
Primary
Concomitant
Flatulence Other Serious 2/18/2010 77 Male 6/29/2010 Physician United States
Primary
Concomitant
Pyrexia Other Serious 6/28/2010 Physician Netherlands
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/30/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/25/2005 50 Male 209 lb 7/5/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/6/2010 Italy
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 6/9/2010 59 Male 7/7/2010 Other Health Professional France
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/7/2010 Italy
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 4/1/2010 93 Male 7/7/2010 Other Health Professional United States
Primary
Concomitant
Skin Exfoliation Hospitalization 8/1/2010 85 Male 196 lb 9/16/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 12/27/2009 63 Male 9/16/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 9/17/2010 United States
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 9/17/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/7/2010 85 Female 150 lb 9/23/2010 Physician United States
Primary
Secondary
Upper Gastrointestinal Haemorrhage Hospitalization 8/6/2010 80 Female 113 lb 9/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vasculitis Other Serious 9/24/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 9/29/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/23/2001 44 Male 161 lb 9/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/25/2005 9/30/2010 United States
Primary
Secondary
Concomitant
5Q Minus Syndrome Other Serious 12/10/2009 70 Male 10/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 8/1/2010 85 Male 196 lb 10/1/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 10/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Cord Compression Hospitalization 9/3/2010 77 Female 108 lb 10/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 8/28/2009 64 Female 153 lb 10/5/2010 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/9/2010 74 Male 150 lb 10/6/2010 Other Health Professional Norfolk Island
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/9/2010 74 Male 150 lb 10/7/2010 Other Health Professional Norfolk Island
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 10/8/2010
Primary
Secondary
Concomitant
Rebound Effect Other Serious 10/8/2010
Primary
Secondary
Concomitant
Rebound Effect Other Serious 10/8/2010
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/21/2010 72 Male 10/8/2010 Physician Italy
Primary
Secondary
Weight Decreased Other Serious 11/1/2001 50 Female 10/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 10/12/2003 73 Male 10/12/2010 United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/1/2010 65 Male 10/20/2010 Consumer France
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/9/2010 74 Male 150 lb 10/20/2010 Other Health Professional Norfolk Island
Primary
Secondary
Concomitant
Vasculitis Hospitalization 8/23/2010 85 Male 121 lb 10/20/2010 Physician Netherlands
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/7/2010 85 Female 150 lb 10/22/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/23/2010 85 Male 121 lb 10/22/2010 Physician Belgium
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/23/2010 10/25/2010 Consumer United States
Primary
Secondary
Concomitant
Splenic Rupture Life Threatening 10/12/2010 68 Female 143 lb 11/1/2010 Physician Netherlands
Primary
Secondary
Concomitant
Cataract Other Serious 7/29/2010 79 Female 111 lb 11/4/2010 Physician United States
Primary
Concomitant
Splenic Rupture Life Threatening 10/12/2010 68 Female 143 lb 11/5/2010 Physician Netherlands
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 2/11/2009 66 Male 11/10/2010 Other Health Professional Israel
Primary
Secondary
Concomitant
Rash Generalised Hospitalization 10/23/2010 90 Male 11/10/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Multiple Myeloma Other Serious 1/1/2010 66 Female 11/11/2010 Physician United States
Primary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 10/29/2010 Male 297 lb 11/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 10/13/2010 76 Female 165 lb 11/17/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vasculitis Hospitalization 8/1/2010 85 Male 196 lb 11/17/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Splenic Rupture Life Threatening 10/12/2010 68 Female 143 lb 11/18/2010 Physician Netherlands
Primary
Secondary
Concomitant
Pneumonia Other Serious 8/28/2009 64 Female 153 lb 11/18/2010 Physician United States
Primary
Concomitant
Multiple Myeloma Life Threatening 10/21/2010 68 Female 143 lb 11/23/2010 Physician Netherlands
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 11/9/2010 77 Female 167 lb 11/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis B Other Serious 10/11/2010 64 Female 161 lb 11/30/2010 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/26/2010 73 Male 136 lb 12/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/21/2010 72 Male 12/8/2010 Physician Italy
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Disability 9/27/2010 71 Male 12/8/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Bile Duct Cancer Hospitalization 10/1/2008 47 Female 12/13/2010 Other Health Professional France
Primary
Secondary
Acute Myeloid Leukaemia Death 2/11/2009 67 Male 2/11/2011 Physician Israel
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 11/4/2010 72 Male 176 lb 2/17/2011 Other Health Professional Italy
Primary
Secondary
Myocardial Ischaemia Death 2/11/2009 67 Male 197 lb 2/28/2011 Physician Israel
Primary
Secondary
Concomitant
Asthenia 76 Female 2/28/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Dispensing Error 77 Female 2/28/2011 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 2/11/2009 67 Male 197 lb 3/11/2011 Physician Israel
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 7/2/2003 55 Male 187 lb 3/17/2011 United States
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious Male 3/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Epistaxis Death 1/1/2010 75 Male 7/12/2010 Physician United States
Primary
Concomitant
Bone Marrow Failure Hospitalization 2/18/2010 77 Male 8/23/2010 Physician United States
Primary
Concomitant
Astrocytoma Other Serious 1/25/2008 68 5/9/2011 Other Health Professional United States
Primary
Secondary
Full Blood Count Decreased Other Serious 9/5/2008 67 Male 5/9/2011 Other Health Professional United States
Primary
Secondary
Breast Cancer Death 12/21/2009 60 5/9/2011 Other Health Professional United States
Primary
Secondary
Arthralgia Other Serious 3/5/2010 73 Female 8/30/2010 Physician United States
Primary
Concomitant
Cholestasis Death 7/23/2009 60 Female 208 lb 5/9/2011 Physician United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 4/1/2010 93 Male 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 3/28/2011 74 Male 195 lb 5/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/23/2011 80 Male 5/11/2011 Physician United States
Primary
Concomitant
Disease Progression Death 7/5/2010 82 Female 8/27/2010 Physician United States
Primary
Concomitant
Proteinuria Other Serious 12/2/2010 64 Male 170 lb 5/11/2011 Other Health Professional Netherlands
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 5/12/2011 Other Health Professional United States
Primary
Secondary
Cerebrovascular Accident Other Serious 8/28/2007 69 Female 5/12/2011 Other Health Professional United States
Primary
Secondary

Drug Data