Melphalan Hydrochloride combined with Prednisone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Constipation Hospitalization 79 Female 6/10/2009 Other Health Professional Denmark
Primary
Concomitant
Sinoatrial Block Hospitalization 5/11/2009 Male 185 lb 6/17/2009 France
Primary
Secondary
Concomitant
Pruritus Hospitalization 5/18/2007 79 Male 152 lb 6/17/2009 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/20/2003 Female 6/17/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonia Death 6/10/2009 Female 154 lb 6/18/2009 Belarus
Primary
Secondary
Concomitant
Neutropenia Other Serious 11/4/2008 Female 97 lb 6/22/2009 Physician France
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 12/1/2008 92 Male 6/23/2009 Physician United States
Primary
Secondary
Concomitant
Vulval Cellulitis Other Serious 9/3/2008 82 Female 6/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/8/2009 Female 238 lb 6/24/2009 Physician Spain
Primary
Secondary
Weight Decreased Other Serious 2/1/2003 Male 6/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/10/2009 80 Female 148 lb 7/21/2009 Physician United States
Primary
Secondary
Sudden Death Death 6/26/2009 Female 112 lb 8/7/2009 Turkey
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 7/10/2009 Male 251 lb 8/7/2009 France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/28/2009 78 Female 172 lb 8/3/2009 Physician Italy
Primary
Secondary
Pneumonia Death 6/10/2009 Female 154 lb 8/10/2009 Belarus
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/12/2009 75 Female 8/6/2009 Physician Spain
Primary
Concomitant
Pyrexia Other Serious 5/23/2009 73 Male 170 lb 8/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Thrombocytopenia Hospitalization 7/10/2009 80 Female 148 lb 8/4/2009 Physician United States
Primary
Secondary
Concomitant
Thrombosis Death 7/5/2009 Female 8/17/2009 Pharmacist United Kingdom
Primary
Concomitant
Pulmonary Thrombosis Other Serious 12/6/2008 Female 8/17/2009 Physician United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 7/10/2009 Male 251 lb 8/17/2009 France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/26/2009 79 Female 148 lb 8/18/2009 Physician United States
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 8/3/2009 79 Male 151 lb 8/11/2009 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 5/10/2009 77 Male 8/20/2009 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 6/1/2008 77 Male 8/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/8/2009 Female 238 lb 8/20/2009 Physician Spain
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 5/4/2009 78 Female 8/26/2009 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/22/2009 Male 210 lb 8/26/2009 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/4/2007 Male 106 lb 8/26/2009 Poland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/20/2003 Female 9/1/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/9/2007 Male 181 lb 9/2/2009 Poland
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 9/5/2008 Male 139 lb 9/2/2009 Greece
Primary
Secondary
Septic Shock Death 2/4/2008 Male 165 lb 9/2/2009 Greece
Primary
Secondary
Brain Stem Infarction Hospitalization 7/31/2009 Male 121 lb 9/3/2009 France
Primary
Secondary
Concomitant
Delirium Hospitalization 8/18/2009 Female 196 lb 9/14/2009 Netherlands
Primary
Secondary
Concomitant
Face Oedema Hospitalization 4/23/2007 Female 110 lb 9/15/2009 Italy
Primary
Secondary
Concomitant
Intestinal Perforation Death Unknown 9/11/2009 France
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 8/3/2009 79 Male 151 lb 9/23/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/7/2008 69 Female 142 lb 9/30/2009 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 6/27/2009 Male 10/21/2009 Physician Austria
Primary
Secondary
Concomitant
Metastatic Malignant Melanoma Other Serious 53 Female 10/23/2009 Other Health Professional United States
Primary
Secondary
Tumour Flare Hospitalization 8/6/2009 Female 127 lb 11/6/2009 Canada
Primary
Secondary
Concomitant
Toxoplasmosis Hospitalization 12/21/2009 Male 121 lb 12/23/2009 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 12/17/2006 72 Male 90 lb 12/23/2009 Physician Taiwan, Province Of China
Primary
Secondary
Hypertension Other Serious 5/14/2009 70 Female 1/12/2010 Consumer Italy
Primary
Secondary
Tooth Extraction Other Serious 1/14/2004 Male 1/12/2010 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/2/2002 Female 125 lb 1/13/2010 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 12/21/2009 Female 104 lb 1/14/2010 Physician France
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2002 Female 195 lb 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Myeloma Hospitalization 12/7/2009 Female 111 lb 1/19/2010 France
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/6/2005 Male 1/21/2010 Physician United States
Primary
Concomitant
Transaminases Increased Hospitalization 1/5/2010 55 Male 151 lb 1/13/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2009 Male 1/22/2010 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2002 Male 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 10/23/2003 Male 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Male 245 lb 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 7/7/2009 Male 1/26/2010 Physician United Kingdom
Primary
Concomitant
Treatment Failure Death 1/1/2008 82 Male 1/21/2010 Sweden
Primary
Concomitant
Cardiac Failure Other Serious 1/1/2008 46 Female 1/21/2010 Netherlands
Primary
Concomitant
Acute Respiratory Failure Death 11/26/2009 1/29/2010 Physician Spain
Primary
Secondary
Concomitant
Tooth Extraction Other Serious Male 1/30/2010 Other Health Professional United States
Primary
Concomitant
Tooth Abscess Other Serious 11/3/2006 Male 1/30/2010 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 3/1/2006 Male 2/4/2010 Physician South Africa
Primary
Concomitant
Lung Infection Hospitalization 1/9/2010 Male 2/4/2010 Physician France
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 5/1/2008 Male 172 lb 2/4/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2003 Male 2/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Retro-orbital Neoplasm Hospitalization 1/22/2010 Male 155 lb 2/5/2010 France
Primary
Secondary
Concomitant
Cataract Hospitalization 6/25/2009 Male 190 lb 2/8/2010 France
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 11/9/2009 Male 176 lb 2/8/2010 Netherlands
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/5/2009 81 Female 144 lb 1/28/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/13/2010 85 Female 207 lb 2/9/2010 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 4/15/2005 Male 195 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 10/11/2004 Female 195 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/1/2006 Male 2/11/2010 Physician South Africa
Primary
Concomitant
Tooth Extraction Other Serious 10/20/1999 Male 178 lb 2/11/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/20/2003 Female 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Male 245 lb 2/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/22/2005 Female 181 lb 2/15/2010 United States
Primary
Concomitant
Neurotoxicity Disability 12/1/2008 Female 2/16/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2002 Female 195 lb 2/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 11/3/2006 Male 169 lb 2/16/2010 Other Health Professional United States
Primary
Concomitant
Transaminases Increased Other Serious 2/16/2010 Physician Spain
Primary
Secondary
Concomitant
Infection Hospitalization 9/28/2009 Female 87 lb 2/16/2010 France
Primary
Secondary
Concomitant
Toothache Other Serious 7/1/2005 Female 2/16/2010 Physician United States
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 11/15/2008 Female 181 lb 2/17/2010 Turkey
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 Male 2/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cataract Operation Hospitalization 6/25/2009 Male 190 lb 2/19/2010 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/15/2005 Male 209 lb 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization Female 2/24/2010 Consumer United States
Primary
Secondary
Syncope Hospitalization 11/17/2009 80 Male 192 lb 3/9/2010 Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 9/28/2009 Female 87 lb 3/9/2010 France
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/20/1999 Male 178 lb 3/11/2010 Consumer United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2007 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Urine Analysis Abnormal Hospitalization 1/9/2010 Male 3/12/2010 Physician France
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 1/27/2004 Male 3/12/2010 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Male 245 lb 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Retro-orbital Neoplasm Hospitalization 1/22/2010 Male 155 lb 3/17/2010 France
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 Female 125 lb 3/17/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/22/2010 Female 3/17/2010 Italy
Primary
Secondary
Concomitant
Thrombocytopenia Death 3/11/2010 Italy
Primary
Secondary
Thrombocytopenia Death Unknown 3/11/2010 Physician Italy
Primary
Secondary
Thrombocytopenia Death 3/11/2010 Italy
Primary
Secondary
Transaminases Increased Other Serious 5/1/2009 3/18/2010 Physician Spain
Primary
Secondary
Concomitant
Spinal Corpectomy Other Serious 7/30/2004 Male 3/18/2010 Physician United States
Primary
Concomitant
Ulcer Other Serious 1/1/2002 Male 3/18/2010 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 9/13/2006 Male 169 lb 3/19/2010 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2004 Female 195 lb 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/14/2007 Male 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/20/2003 Female 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 3/8/2010 Female 159 lb 3/23/2010 Belgium
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 1/1/2009 89 Male 163 lb 3/24/2010 United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2007 3/24/2010 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/22/2005 Female 181 lb 3/24/2010 United States
Primary
Concomitant
Urinary Hesitation Other Serious 1/14/2007 Male 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Other Serious 9/1/2009 Female 3/29/2010 Greece
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 Female 125 lb 3/30/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2002 Female 195 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2007 3/31/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/13/2007 Male 3/31/2010 Physician Austria
Primary
Secondary
General Physical Health Deterioration Hospitalization 11/13/2007 84 Male 154 lb 4/8/2010 Austria
Primary
Secondary
Multi-organ Failure Death 73 Male 4/9/2010 Israel
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/22/2005 80 Female 181 lb 4/9/2010 United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2004 64 Female 195 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/8/2009 78 Female 154 lb 4/14/2010 Belarus
Primary
Secondary
Transient Ischaemic Attack Other Serious 4/15/2010 Italy
Primary
Secondary
Concomitant
Multiple Myeloma Death 1/1/2010 60 Female 4/15/2010 Other Health Professional Israel
Primary
Concomitant
Respiratory Failure Hospitalization 4/1/2010 Female 4/15/2010 Consumer United States
Primary
Secondary
Weight Decreased Other Serious 3/14/1999 48 Male 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Hospitalization 2/1/2010 83 Female 99 lb 4/19/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 4/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venous Insufficiency Other Serious 2/1/1998 60 Male 4/19/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 56 Male 4/19/2010 United States
Primary
Secondary
Concomitant
Vertebroplasty Other Serious 4/19/2001 81 Male 165 lb 4/19/2010 United States
Primary
Concomitant
Vertebroplasty Other Serious 4/19/2001 81 Male 165 lb 4/21/2010 United States
Primary
Concomitant
Neurotoxicity Disability 12/1/2008 77 Female 4/22/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2003 56 Male 4/22/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/1/2010 59 Female 150 lb 4/23/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2005 61 Male 245 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Cirrhosis Hospitalization 3/18/2010 4/29/2010 Physician Germany
Primary
Secondary
Multi-organ Failure Death 73 Male 4/29/2010 Israel
Primary
Concomitant
Gastric Cancer Other Serious 4/20/2010 4/29/2010 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Other Serious 3/29/2010 73 Male 150 lb 4/29/2010 Switzerland
Primary
Secondary
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 4/29/2010 United States
Primary
Secondary
Concomitant
International Normalised Ratio Other Serious 3/29/2010 73 Male 150 lb 4/30/2010 Switzerland
Primary
Secondary
Weight Decreased Other Serious 4/15/2005 50 Male 209 lb 5/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 65 Male 5/5/2010
Primary
Secondary
Drug Eruption Hospitalization 2/20/2010 5/6/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 4/1/2010 76 Female 5/6/2010 Consumer United States
Primary
Secondary

Drug Data