Melphalan Hydrochloride combined with Prednisolone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Leukopenia Death 67 Female 6/23/2009 Other Health Professional Germany
Primary
Secondary
Swelling Other Serious 4/25/2009 Female 106 lb 6/26/2009 Physician Korea, Republic Of
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 8/1/2006 51 Male 7/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Mucosal Inflammation Other Serious 8/1/2006 51 Male 7/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Karyotype Analysis Abnormal Hospitalization 82 Female 8/3/2009 Japan
Primary
Concomitant
Pyrexia Other Serious 1/26/2009 Female 121 lb 8/12/2009 Turkey
Primary
Secondary
Transplant Failure Other Serious 69 Male 8/17/2009 United States
Primary
Secondary
Vomiting Other Serious 7/1/2006 64 Male 8/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metastatic Malignant Melanoma Other Serious 53 Female 10/23/2009 Other Health Professional United States
Primary
Secondary
Vomiting Other Serious 1/11/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Ureteric Obstruction Other Serious 10/4/2009 69 Male 154 lb 1/14/2010 Physician Germany
Primary
Concomitant
Pyrexia Hospitalization 10/25/2009 1/28/2010 Physician Italy
Primary
Concomitant
Tooth Extraction Other Serious Male 1/30/2010 Other Health Professional United States
Primary
Concomitant
Neuropathy Peripheral Death 2/4/2010 Physician Australia
Primary
Concomitant
Sudden Death Death 2/1/2005 Male 240 lb 2/11/2010 Russian Federation
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 70 Male 2/26/2010 Physician Japan
Primary
Concomitant
Sudden Death Death 3/23/2009 Male 240 lb 3/12/2010 Russian Federation
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 3/1/2009 Female 88 lb 3/12/2010 Physician Japan
Primary
Secondary
Concomitant
Ulcer Other Serious 1/1/2002 Male 3/18/2010 Other Health Professional United States
Primary
Concomitant
Septic Shock Life Threatening 6/17/2007 Male 3/18/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 50 Male 3/23/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/10/2010 Male 3/29/2010 Netherlands
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 12/16/2008 73 Male 117 lb 3/24/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 4/8/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Toothache Other Serious 7/1/2005 62 Female 4/12/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2005 61 Male 245 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 4/14/2010 United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 11/13/2007 84 Male 154 lb 4/14/2010 Austria
Primary
Secondary
Visual Impairment Other Serious 7/12/1999 63 Female 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 9/13/2006 68 Male 169 lb 4/15/2010 Other Health Professional United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 3/11/2010 76 Male 4/28/2010 Netherlands
Primary
Concomitant
Erythema Multiforme Other Serious 79 Male 4/29/2010 Germany
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 79 Male 5/7/2010 Austria
Primary
Secondary
Concomitant
Sweat Gland Tumour Required Intervention 32 Male 6/2/2010 Physician United Kingdom
Primary
Secondary
Thrombocytopenia Life Threatening 10/4/2009 69 Male 150 lb 6/2/2010 Physician Germany
Primary
Concomitant
Sweat Gland Tumour Other Serious 32 Male 6/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Sweat Gland Tumour Other Serious 32 Female 6/15/2010 Physician United Kingdom
Primary
Secondary
Ulcer Other Serious 1/1/2002 81 Male 6/15/2010 United States
Primary
Concomitant
Sweat Gland Tumour Other Serious 32 Male 6/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Sweat Gland Tumour Other Serious 32 Male 6/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Sweat Gland Tumour Required Intervention 28 Male 6/17/2010 Consumer United Kingdom
Primary
Secondary
Disease Progression 9/1/2004 64 Male 7/9/2010 Italy
Primary
Concomitant
Sepsis Other Serious 22 Female 9/20/2010 Other Health Professional France
Primary
Secondary
Stress Cardiomyopathy Hospitalization 6/7/2007 67 Female 9/20/2010 Other Health Professional Japan
Primary
Secondary
Sepsis Other Serious 8/16/2010 76 Female 9/21/2010 Physician United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 7/25/2009 9/23/2010 Physician Belgium
Primary
Concomitant
Pneumonia Other Serious 6/12/2009 79 Female 9/27/2010 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 9/8/2010 71 Male 9/29/2010 Physician France
Primary
Secondary
Concomitant
Liver Injury Other Serious 59 Female 10/4/2010 Consumer Japan
Primary
Secondary
Concomitant
Ulcer Other Serious 1/1/2002 81 Male 10/7/2010 United States
Primary
Concomitant
Ulcer Other Serious 1/1/2002 81 Male 10/7/2010 United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 7/25/2009 10/7/2010 Physician Belgium
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/10/2009 4 Female 31 lb 10/8/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/10/2009 4 Female 31 lb 10/11/2010 Physician Japan
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Other Serious 0 Male 10/14/2010 Physician Germany
Primary
Secondary
Concomitant
Pruritus Hospitalization 9/30/2009 18 Female 137 lb 10/18/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 8/27/2010 71 Male 181 lb 10/19/2010 Physician Germany
Primary
Secondary
Concomitant
Varicella Virus Test Positive Other Serious 24 Female 154 lb 10/25/2010 Other Health Professional Japan
Primary
Concomitant
Pneumonia Life Threatening 6/23/2010 10/29/2010 Physician Japan
Primary
Secondary
Concomitant
Urinary Incontinence Life Threatening 10/17/2010 72 Male 236 lb 11/1/2010 Physician New Zealand
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/20/2010 75 Male 115 lb 11/8/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Deep Vein Thrombosis Life Threatening 90 10/28/2010 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 25 Female 11/9/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 20 Female 11/9/2010 Other Health Professional Japan
Primary
Concomitant
Pneumonia Life Threatening 6/23/2010 11/10/2010 Physician Japan
Primary
Secondary
Concomitant
Varicella Virus Test Positive Other Serious 10/1/2007 21 Female 154 lb 11/12/2010 Other Health Professional Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 25 Female 11/15/2010 Physician Japan
Primary
Concomitant
Urinary Incontinence Life Threatening 10/17/2010 72 Male 236 lb 11/15/2010 Physician New Zealand
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/21/2010 71 Female 165 lb 11/15/2010 Physician Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 9/24/2010 67 Female 170 lb 11/18/2010 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2009 11/23/2010 Physician Japan
Primary
Concomitant
Neuropathy Peripheral Hospitalization 11/9/2009 11/23/2010 Physician Australia
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 5/26/2010 Male 18 lb 11/24/2010 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 9/8/2010 71 Male 124 lb 11/29/2010 Physician France
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/30/2010 71 Male 132 lb 11/29/2010 Physician France
Primary
Secondary
Shock Haemorrhagic Other Serious 4/23/2009 54 Female 115 lb 11/12/2010 Physician Japan
Primary
Concomitant
Urinary Incontinence Life Threatening 10/17/2010 72 Male 236 lb 12/10/2010 Physician New Zealand
Primary
Secondary
Concomitant
Brain Natriuretic Peptide Increased Other Serious 12/11/2010 Physician Thailand
Primary
Concomitant
Pseudomonal Sepsis Life Threatening 11/7/2010 49 Female 97 lb 12/30/2010 Physician Japan
Primary
Secondary
Concomitant
Disorientation Death 4/13/2009 52 Male 117 lb 1/10/2011 Physician Japan
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 39 Female 2/28/2011 Other Health Professional Australia
Primary
Secondary
Chronic Graft Versus Host Disease Death 20 Female 3/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 28 Female 3/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Death 12/13/2010 3/17/2011 Physician Japan
Primary
Secondary
Concomitant
Epstein-barr Virus Test Positive Other Serious 1 Female 3/18/2011 Physician Japan
Primary
Concomitant
Encephalopathy Other Serious 55 Male 3/18/2011 Physician Japan
Primary
Concomitant
Multiple Myeloma Death 64 Male 4/4/2011 Other Health Professional Japan
Primary
Secondary
Multiple Myeloma Death 64 Male 4/1/2011 Other Health Professional Japan
Primary
Secondary
Atrial Fibrillation Hospitalization 8/12/2010 80 Male 213 lb 4/13/2011 Physician Portugal
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/25/2008 87 Female 140 lb 5/9/2011 Physician Spain
Primary
Secondary
Erythema Hospitalization 5/23/2008 82 Male 148 lb 5/10/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Platelet Count Increased Hospitalization 5/23/2008 82 Male 148 lb 5/10/2011 Physician Sweden
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 11/29/2007 76 Male 143 lb 5/10/2011 Physician Ukraine
Primary
Secondary
Diabetic Ketoacidosis Other Serious 70 Female 5/11/2011 Other Health Professional Japan
Primary
Secondary
Liver Disorder Other Serious 70 Female 5/23/2011 Other Health Professional Japan
Primary
Secondary
Diverticulitis Hospitalization 6/2/2010 80 Male 165 lb 5/27/2011 Physician Germany
Primary
Secondary
Diverticulitis Hospitalization 6/2/2010 5/27/2011 Physician Germany
Primary
Secondary
Lividity Hospitalization 70 Female 6/2/2011 Other Health Professional Japan
Primary
Secondary
Refractory Anaemia With An Excess Of Blasts Death 12/1/2010 58 Male 6/2/2011 Other Health Professional France
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 6/2/2010 6/2/2011 Other Health Professional Germany
Primary
Secondary
Diverticulitis Hospitalization 6/2/2010 80 Male 165 lb 6/8/2011 Physician Germany
Primary
Secondary
Erythema Multiforme Hospitalization 70 Female 6/14/2011 Other Health Professional Japan
Primary
Secondary
Type 1 Diabetes Mellitus Hospitalization 1/1/2010 70 Female 6/21/2011 Other Health Professional Japan
Primary
Secondary
Phlebitis Other Serious 6/1/2011 6/29/2011 Physician Portugal
Primary
Concomitant
Pancreatitis Other Serious 2/10/2010 23 Male 117 lb 6/30/2011 Physician Japan
Primary
Secondary
Concomitant
Epstein-barr Virus Infection Other Serious 70 Female 6/30/2011 Other Health Professional Japan
Primary
Secondary
Hypertension Life Threatening 4/22/2010 13 Male 90 lb 7/5/2011 Physician Japan
Primary
Concomitant
Memory Impairment Hospitalization 2/10/2010 23 Male 117 lb 7/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/15/2011 7/8/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 70 Female 6/27/2011 Other Health Professional Japan
Primary
Secondary
Gastrointestinal Disorder Other Serious 1 Female 6/23/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Ileus Hospitalization 9/7/2009 7/13/2011 Consumer Germany
Primary
Concomitant
Bone Fissure Other Serious 4/1/2008 72 Female 161 lb 7/13/2011 Physician Germany
Primary
Concomitant
Plasmacytoma Other Serious 60 Male 7/14/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Peripheral Sensorimotor Neuropathy Hospitalization 6/15/2011 7/18/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Gingival Infection Other Serious 12/1/2010 76 Female 137 lb 7/20/2011 Physician Germany
Primary
Concomitant
Accidental Overdose Other Serious 6/26/2011 7/28/2011 Physician Iran (Islamic Republic Of)
Primary
Concomitant
Pneumocystis Jiroveci Infection Death 7/28/2011 Physician Iran (Islamic Republic Of)
Primary
Concomitant
Constipation Hospitalization 2/1/2006 85 Male 7/29/2011 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/10/2010 49 Female 97 lb 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Decreased Hospitalization 1/26/2011 2 Male 27 lb 7/26/2011 Physician France
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious Female 8/3/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Death 11/10/2010 49 Female 97 lb 8/3/2011 Physician Japan
Primary
Secondary
Concomitant
Metastases To Liver Death Male 7/27/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 20 Female 8/8/2011 Physician Japan
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 59 Male 8/10/2011 Physician Sweden
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Infection Death 8/11/2011 Physician Iran (Islamic Republic Of)
Primary
Concomitant
Graft Versus Host Disease Disability 4/20/2011 58 Male 119 lb 8/11/2011 Physician Japan
Primary
Concomitant
Gingival Swelling Other Serious 12/1/2007 77 Male 8/15/2011 Other Health Professional Japan
Primary
Concomitant
Abdominal Distension Hospitalization 8/3/2011 8/16/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Accidental Overdose Other Serious 6/26/2011 8/18/2011 Physician Iran (Islamic Republic Of)
Primary
Concomitant
Disease Progression Hospitalization 2/10/2009 57 Female 4/16/2011 Other Health Professional Japan
Primary
Concomitant
Death Death 8/19/2011 Consumer United Kingdom
Primary
Secondary
Diverticulitis Hospitalization 6/2/2010 80 Male 165 lb 8/18/2011 Physician Germany
Primary
Secondary
Diabetic Ketoacidosis Hospitalization 9/29/2006 Female 243 lb 8/17/2011 Other Health Professional Japan
Primary
Secondary
Infection Death 9/9/2011 Other Health Professional France
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 8 Male 9/12/2011 Physician Japan
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Death 11/17/2009 6 Male 33 lb 9/19/2011 Physician Japan
Primary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 5/19/2009 10 Male 49 lb 9/19/2011 Physician Japan
Primary
Concomitant
Septic Shock Hospitalization 3/26/2011 56 Male 183 lb 9/20/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Life Threatening 10/21/2009 22 Female 104 lb 9/26/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 10/21/2009 22 Female 104 lb 9/26/2011 Physician Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 3/1/2011 9/26/2011 Physician Turkey
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 2/5/2008 55 Female 9/15/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 12/15/2010 77 Male 181 lb 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Enterococcal Infection Hospitalization 2/10/2010 23 Male 117 lb 10/3/2011 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 9/6/2011 10/6/2011 Physician Korea, Republic Of
Primary
Secondary
Rhabdomyolysis Other Serious 10/7/2011 Japan
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 10/21/2009 22 Female 104 lb 10/11/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Life Threatening 12/15/2010 77 Male 181 lb 10/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data