Melphalan Hydrochloride combined with Omeprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Febrile Neutropenia Other Serious 40 Male 165 lb 6/25/2009 Physician Spain
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/4/2007 Male 106 lb 8/26/2009 Poland
Primary
Secondary
Concomitant
Cardiogenic Shock Hospitalization 7/27/2008 Male 128 lb 8/28/2009 Poland
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/9/2007 Male 181 lb 9/2/2009 Poland
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 9/9/2008 Male 168 lb 9/9/2009 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 12/4/2007 Male 106 lb 9/10/2009 Poland
Primary
Secondary
Concomitant
Weight Increased Hospitalization 9/13/2009 72 Female 10/12/2009 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 5/9/2009 41 Male 165 lb 1/11/2010 Physician Spain
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/2/2002 Female 125 lb 1/13/2010 United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 10/23/2003 Male 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 7/7/2009 Male 1/26/2010 Physician United Kingdom
Primary
Concomitant
Cellulitis Hospitalization 11/18/2009 Female 234 lb 1/27/2010 Physician United States
Primary
Secondary
Concomitant
Erythema Hospitalization 11/18/2009 69 Female 234 lb 2/3/2010 Physician United States
Primary
Secondary
Concomitant
Cataract Hospitalization 6/25/2009 Male 190 lb 2/8/2010 France
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 11/9/2009 Male 176 lb 2/8/2010 Netherlands
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 2/16/2010 Physician Spain
Primary
Secondary
Concomitant
Cataract Operation Hospitalization 6/25/2009 Male 190 lb 2/19/2010 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/15/2005 Male 209 lb 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 Female 125 lb 3/17/2010 United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 5/1/2009 3/18/2010 Physician Spain
Primary
Secondary
Concomitant
Ulcer Other Serious 1/1/2002 Male 3/18/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 4/15/2005 Male 209 lb 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/10/2010 Male 3/29/2010 Netherlands
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 Female 125 lb 3/30/2010 United States
Primary
Secondary
Concomitant
Tremor Hospitalization 3/14/2010 67 Male 203 lb 4/1/2010 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 1/10/2010 76 Male 4/5/2010 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 4/14/2010 United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 3/24/2010 60 Male 172 lb 4/15/2010 Consumer United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2005 61 Male 245 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/11/2010 76 Male 4/28/2010 Netherlands
Primary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 4/29/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/15/2005 50 Male 209 lb 5/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 5/12/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 5/28/2010 United States
Primary
Secondary
Concomitant
Cataract Hospitalization 5/24/2010 67 Male 190 lb 6/10/2010 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/22/2010 63 Female 123 lb 6/11/2010 Physician United States
Primary
Secondary
Concomitant
Cataract Hospitalization 11/25/2009 67 Male 190 lb 6/11/2010 Other Health Professional France
Primary
Secondary
Concomitant
Syncope Hospitalization 5/31/2010 63 Female 131 lb 6/15/2010 Physician United States
Primary
Secondary
Concomitant
Ulcer Other Serious 1/1/2002 81 Male 6/15/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 6/21/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 61 Male 245 lb 6/21/2010 United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 6/4/2010 63 Female 131 lb 6/22/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 61 Male 245 lb 6/29/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/21/2010 63 Female 145 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/25/2005 50 Male 209 lb 7/5/2010 United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 6/23/2010 69 Male 174 lb 7/7/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Restrictive Cardiomyopathy Other Serious 6/21/2010 63 Female 7/9/2010 Physician United States
Primary
Secondary
Concomitant
Cataract Operation Hospitalization 5/24/2010 67 Male 190 lb 9/14/2010 Physician France
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 9/17/2010 United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 6/23/2010 69 Male 174 lb 9/17/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 9/29/2010 United States
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 9/13/2010 60 Female 220 lb 9/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/25/2005 9/30/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 79 Male 180 lb 10/4/2010 Consumer United States
Primary
Secondary
Concomitant
Ulcer Other Serious 1/1/2002 81 Male 10/7/2010 United States
Primary
Concomitant
Ulcer Other Serious 1/1/2002 81 Male 10/7/2010 United States
Primary
Concomitant
Cataract Hospitalization 5/24/2010 67 Male 190 lb 10/8/2010 Other Health Professional France
Primary
Secondary
Concomitant
Cataract Operation Hospitalization 5/24/2010 67 Male 190 lb 10/12/2010 Physician France
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 9/20/2010 85 Male 139 lb 10/12/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Cataract Hospitalization 11/25/2009 67 Male 190 lb 10/13/2010 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 9/29/2010 65 Male 221 lb 10/14/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 9/29/2010 65 Male 221 lb 10/19/2010 Physician Spain
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 10/20/2010 United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 9/29/2010 65 Male 221 lb 10/29/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Urinary Incontinence Life Threatening 10/17/2010 72 Male 236 lb 11/1/2010 Physician New Zealand
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 9/20/2010 85 Male 139 lb 11/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 9/29/2010 65 Male 221 lb 11/8/2010 Physician Spain
Primary
Secondary
Concomitant
Rash Generalised Hospitalization 10/23/2010 90 Male 11/10/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Urinary Incontinence Life Threatening 10/17/2010 72 Male 236 lb 11/15/2010 Physician New Zealand
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 10/11/2010 80 Male 210 lb 11/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 10/11/2010 80 Male 210 lb 11/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/21/2010 72 Male 12/8/2010 Physician Italy
Primary
Secondary
Concomitant
Urinary Incontinence Life Threatening 10/17/2010 72 Male 236 lb 12/10/2010 Physician New Zealand
Primary
Secondary
Concomitant
Pseudomonal Sepsis Life Threatening 11/7/2010 49 Female 97 lb 12/30/2010 Physician Japan
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 1/26/2011 74 Female 206 lb 5/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 1/26/2011 74 Female 206 lb 5/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 1/2/2011 5/11/2011 Consumer United States
Primary
Secondary
Concomitant
Proteinuria Other Serious 12/2/2010 64 Male 170 lb 5/11/2011 Other Health Professional Netherlands
Primary
Concomitant
Atrial Fibrillation Death 12/28/2010 68 Female 5/10/2011 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 4/3/2011 70 Male 154 lb 5/13/2011 Physician United States
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 9/21/2008 55 Male 161 lb 5/13/2011 Consumer Portugal
Primary
Secondary
Concomitant
Chronic Myelomonocytic Leukaemia Other Serious 6/26/2009 75 Female 5/13/2011 Physician Italy
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Intestine Hospitalization 4/9/2011 42 Female 197 lb 5/15/2011 Physician United States
Primary
Secondary
Concomitant
Electrocardiogram T Wave Abnormal Other Serious 3/17/2009 66 Female 273 lb 5/16/2011 Consumer United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 4/21/2011 5/16/2011 Physician Italy
Primary
Secondary
Concomitant
Renal Disorder Hospitalization Male 5/16/2011 Consumer Brazil
Primary
Concomitant
Surgery Other Serious 9/1/2010 48 Male 154 lb 5/17/2011 Consumer Brazil
Primary
Concomitant
Syncope Hospitalization 5/3/2011 70 Female 5/20/2011 Physician United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 7/1/2010 75 Male 159 lb 5/20/2011 Other Health Professional United States
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 4/1/2011 63 Male 5/20/2011 Netherlands
Primary
Concomitant
Cell Death Hospitalization 3/1/2010 63 Male 5/20/2011 Consumer France
Primary
Secondary
Concomitant
Sepsis Life Threatening 3/3/2010 77 Female 5/23/2011 Consumer Czech Republic
Primary
Secondary
Concomitant
Insomnia Other Serious 3/11/2002 65 Female 5/25/2011 Physician United States
Primary
Concomitant
Sepsis Other Serious 6/20/2003 61 Male 6/11/2011 Physician Spain
Primary
Concomitant
Headache Other Serious 3/11/2002 65 Female 6/21/2011 Physician United States
Primary
Concomitant
Febrile Neutropenia Life Threatening 7/18/2010 61 Female 110 lb 6/21/2011 Physician Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease Hospitalization 5/25/2010 23 Female 73 lb 6/23/2011 Physician Japan
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 2/1/1998 60 Male 6/28/2011 Physician United States
Primary
Secondary
Concomitant
Dermatitis Contact Other Serious 7/1/2002 59 Female 142 lb 6/29/2011 Lawyer United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 5/19/2011 90 Male 172 lb 7/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatic Atrophy Hospitalization 3/11/2002 65 Female 7/12/2011 United States
Primary
Concomitant
Nocturia Hospitalization 3/11/2002 65 Female 7/28/2011 Other Health Professional United States
Primary
Concomitant
Constipation Hospitalization 2/1/2006 85 Male 7/29/2011 Other Health Professional United States
Primary
Concomitant
Proteinuria Other Serious Male 132 lb 7/29/2011 Lawyer United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/10/2010 49 Female 97 lb 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
Multiple Myeloma Death 1/1/2010 64 Male 8/2/2011 Physician United States
Primary
Concomitant
Febrile Neutropenia Death 11/10/2010 49 Female 97 lb 8/3/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Life Threatening 1/17/2011 27 Female 95 lb 8/5/2011 Physician Japan
Primary
Concomitant
Adrenal Mass Disability 3/11/2002 65 Female 8/5/2011 United States
Primary
Concomitant
Insomnia Other Serious 11/23/2010 62 Female 108 lb 8/8/2011 Physician Japan
Primary
Concomitant
Osteopenia Hospitalization Male 132 lb 8/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 2/17/2011 73 Male 205 lb 8/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 10/23/2003 56 Male 9/4/2011 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Hospitalization Male 178 lb 9/26/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/11/2009 23 Female 97 lb 9/29/2011 Physician Japan
Primary
Concomitant
Acute Myeloid Leukaemia Death 12/15/2010 77 Male 181 lb 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Test Positive Death 12/15/2010 52 Male 150 lb 10/7/2011 Physician Japan
Primary
Concomitant
Acute Myeloid Leukaemia Life Threatening 12/15/2010 77 Male 181 lb 10/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Injury Hospitalization 3/11/2002 65 Female 10/14/2011 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Hospitalization Male 178 lb 10/14/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Calculus Bladder Other Serious Female 184 lb 10/19/2011 Consumer United States
Primary
Concomitant
Oesophagitis Other Serious Female 184 lb 11/3/2011 Lawyer United States
Primary
Concomitant
Myelodysplastic Syndrome Death 3/3/2010 77 Female 11/8/2011 Physician Czech Republic
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Other Serious Female 184 lb 11/10/2011 Lawyer United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Hospitalization 7/11/2011 77 Male 178 lb 11/15/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Hypoacusis Other Serious 2/1/2006 85 Male 11/15/2011 Physician United States
Primary
Concomitant
Hypokalaemia Other Serious Female 184 lb 11/16/2011 Consumer United States
Primary
Concomitant
Synovial Rupture Hospitalization 9/1/2003 46 Male 130 lb 11/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Erectile Dysfunction Hospitalization 9/1/2003 46 Male 130 lb 11/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Life Threatening 3/3/2010 77 Female 11/18/2011 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Hepatomegaly Hospitalization 5/10/2010 56 Male 132 lb 11/22/2011 Physician Japan
Primary
Concomitant
Intestinal Perforation Hospitalization 8/15/2011 11/23/2011 Other Health Professional Italy
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious Female 184 lb 11/24/2011 Physician United States
Primary
Concomitant
Nausea Death 4/11/2008 72 Male 11/29/2011 Physician Japan
Primary
Concomitant
Cervical Spinal Stenosis Other Serious 9/1/2003 46 Male 130 lb 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Viral Haemorrhagic Cystitis Death 6/24/2010 29 Female 99 lb 12/8/2011 Other Health Professional Japan
Primary
Concomitant
Oral Herpes Other Serious 4/27/2011 60 Female 82 lb 12/13/2011 Physician Japan
Primary
Secondary
Concomitant
Oral Herpes Life Threatening 4/27/2011 60 Female 82 lb 12/13/2011 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Chorioretinitis Hospitalization 8/24/2009 21 Male 104 lb 12/20/2011 Physician Japan
Primary
Concomitant
Abdominal Pain Hospitalization 9/1/2003 46 Male 130 lb 1/2/2012 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Disability 3/14/2011 25 Male 123 lb 1/3/2012 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Death 4/14/2008 73 Male 1/11/2012 Physician Japan
Primary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 2/12/2011 73 Male 205 lb 1/12/2012 Physician United States
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 2/12/2011 73 Male 205 lb 1/19/2012 Physician United States
Primary
Secondary
Concomitant
Vascular Pseudoaneurysm Other Serious 9/1/2003 46 Male 130 lb 2/1/2012 Lawyer United States
Primary
Secondary
Concomitant
Pyrexia Death 2/1/2006 85 Male 2/8/2012 Lawyer United States
Primary
Concomitant
Syncope Hospitalization 51 Female 239 lb 2/9/2012 Physician United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Death 1/25/2012 50 Female 144 lb 2/10/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Anxiety Other Serious Male 132 lb 2/14/2012 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 3/3/2010 77 Female 2/21/2012 Physician Czech Republic
Primary
Secondary
Concomitant

Drug Data