Marcumar combined with Torsemide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Necrosis Disability 9/10/2005 75 Female 123 lb 2/3/2006 Physician Germany
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 82 Male 8/14/2006 Physician Germany
Primary
Concomitant
Cardiac Arrest Death 6/16/2006 57 Male 9/18/2006 Physician Germany
Primary
Concomitant
Sudden Death Death 6/16/2006 57 Male 179 lb 10/5/2006 Physician Germany
Primary
Concomitant
Vision Blurred Other Serious 9/1/2006 78 Female 11/14/2006 Other Health Professional Germany
Primary
Concomitant
Visual Disturbance Other Serious 9/1/2006 78 Female 11/30/2006 Germany
Primary
Concomitant
Traumatic Brain Injury Death 80 Male 187 lb 12/15/2006 Physician Germany
Primary
Concomitant
Autoimmune Thrombocytopenia Hospitalization 12/5/2005 Male 254 lb 3/7/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Lymphoedema Hospitalization 10/1/2006 77 Female 3/14/2007 Germany
Primary
Concomitant
Stent Placement Other Serious 3/6/2007 69 Female 4/3/2007 Physician Germany
Primary
Secondary
Concomitant
Visual Disturbance Hospitalization 9/1/2006 42 Male 205 lb 5/11/2007 Physician Germany
Primary
Concomitant
Sepsis Required Intervention 3/29/2007 58 Female 132 lb 5/8/2007 Physician Germany
Primary
Concomitant
Muscle Twitching Hospitalization 1/1/2007 Female 5/23/2007 Physician Germany
Primary
Concomitant
Oedema Peripheral Death 1/1/2002 76 Female 5/25/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 5/1/2007 Female 6/1/2007 Physician Germany
Primary
Concomitant
Renal Failure Other Serious 8/14/2005 78 Male 194 lb 6/4/2007 Physician Germany
Primary
Concomitant
Haematuria Other Serious 1/1/2007 Male 220 lb 6/7/2007 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 60 Female 6/24/2007 Consumer Germany
Primary
Concomitant
Hepatocellular Damage Hospitalization 10/14/2005 71 Male 6/28/2007 Consumer Switzerland
Primary
Secondary
Concomitant
Melaena Hospitalization 2/1/2007 79 Male 6/28/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 4/1/2007 Female 7/6/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 6/12/2007 Female 128 lb 7/20/2007 Physician Switzerland
Primary
Concomitant
Vomiting Other Serious 1/1/2007 60 Female 8/15/2007 Consumer Germany
Primary
Concomitant
Pyrexia Other Serious 7/1/2007 75 Female 8/17/2007 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 7/1/2007 75 Female 8/17/2007 Physician Germany
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/29/2007 77 Male 8/28/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/2007 81 Male 9/10/2007 Other Health Professional France
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2007 Male 9/26/2007 Consumer Germany
Primary
Concomitant
Syncope Hospitalization 9/9/2007 69 Female 10/25/2007 Physician Switzerland
Primary
Concomitant
Interacting
Fatigue Other Serious Female 10/29/2007 Other Health Professional Switzerland
Primary
Concomitant
Renal Failure Other Serious 1/1/2007 Male 10/29/2007 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization Female 11/18/2007 Physician Germany
Primary
Concomitant
Proctitis Haemorrhagic Other Serious 8/20/2007 62 Male 11/28/2007 Germany
Primary
Concomitant
Torsade De Pointes Other Serious 6/10/2007 81 Female 132 lb 2/11/2008 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 1/31/2005 69 Male 2/13/2008 Physician Germany
Primary
Secondary
Concomitant
Tachycardia Hospitalization 1/1/2008 Male 2/29/2008 Other Health Professional Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 12/15/2004 59 Male 3/4/2008 Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 12/15/2004 59 Male 3/7/2008 Physician Germany
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 12/15/2004 59 Male 3/19/2008 Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/26/2008 86 Male 4/7/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/26/2008 86 Male 4/7/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 7/27/2007 31 Male 4/21/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypotension Hospitalization 2/6/2006 5/2/2008 Consumer Germany
Primary
Secondary
Concomitant
Interacting
Skin Toxicity Hospitalization Male 181 lb 5/7/2008 Physician Germany
Primary
Concomitant
Skin Toxicity Hospitalization 3/1/2008 Male 181 lb 5/8/2008 Physician Germany
Primary
Concomitant
Skin Toxicity Hospitalization 3/1/2008 Male 181 lb 5/23/2008 Physician Germany
Primary
Concomitant
Transaminases Increased Other Serious 10/9/2007 Female 104 lb 7/24/2008 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/1/2008 60 Male 9/5/2008 Physician Switzerland
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 5/29/2008 Male 9/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Dermatitis Exfoliative Hospitalization 55 Male 10/1/2008 Physician Germany
Primary
Concomitant
Drug Prescribing Error Hospitalization 7/25/2008 79 Female 183 lb 10/21/2008 Other Health Professional France
Primary
Concomitant
Interacting
Thrombotic Microangiopathy Life Threatening 4/28/2008 52 Female 12/22/2008 Other Health Professional Germany
Primary
Concomitant
Pulmonary Congestion Hospitalization 11/9/2008 72 Male 12/30/2008 Physician Germany
Primary
Concomitant
Dermatitis Exfoliative Hospitalization 55 Male 1/8/2009 Physician Germany
Primary
Concomitant
Thrombotic Microangiopathy Life Threatening 4/28/2008 52 Female 1/21/2009 Other Health Professional Germany
Primary
Concomitant
Prothrombin Time Shortened Other Serious 1/30/2009 68 Female 2/25/2009 Consumer Germany
Primary
Concomitant
Syncope Hospitalization 10/17/2008 89 Male 3/2/2009 Physician Switzerland
Primary
Concomitant
Dermatitis Exfoliative Other Serious 55 Male 3/6/2009 Physician Germany
Primary
Concomitant
Dermatitis Exfoliative Other Serious 55 Male 3/13/2009 Physician Germany
Primary
Concomitant
Tachyarrhythmia Life Threatening 6/24/2008 Female 284 lb 3/13/2009 Physician Germany
Primary
Secondary
Concomitant
Optic Atrophy Hospitalization 6/3/2008 59 Male 3/18/2009 Physician Germany
Primary
Concomitant
Haemorrhage Hospitalization 10/27/2008 72 Male 258 lb 3/31/2009 Other Health Professional Germany
Primary
Secondary
Interacting
Death Hospitalization 1/1/2009 79 192 lb 4/8/2009 Physician Germany
Primary
Concomitant
Septic Shock Other Serious 12/14/2008 Female 4/29/2009 Physician Germany
Primary
Concomitant
Wound Infection Hospitalization 1/26/2009 74 Male 5/20/2009 Physician Germany
Primary
Concomitant
Ultrasound Scan Abnormal Hospitalization 62 Female 5/21/2009 Physician Germany
Primary
Secondary
Death Life Threatening 1/1/2009 79 Male 192 lb 6/4/2009 Physician Germany
Primary
Concomitant
Multi-organ Disorder Death 11/26/2008 Male 265 lb 5/29/2009 Germany
Primary
Concomitant
Hyperthyroidism Hospitalization 10/30/2008 Male 265 lb 5/29/2009 Physician Germany
Primary
Concomitant
Drug Interaction Hospitalization 3/1/2009 87 Female 7/1/2009 Physician Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased Required Intervention 5/26/2009 77 Male 7/9/2009 Germany
Primary
Concomitant
Paraesthesia Hospitalization 6/11/2009 Female 187 lb 7/21/2009 Physician Switzerland
Primary
Concomitant
Right Ventricular Failure Hospitalization 2/5/2009 Female 8/10/2009 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 11/1/2008 82 Male 8/27/2009 Physician Switzerland
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 62 Female 8/28/2009 Physician Germany
Primary
Secondary
Thrombocytopenia Life Threatening 8/13/2009 Female 154 lb 9/24/2009 Physician
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 7/29/2009 63 Female 9/24/2009 Other Health Professional Switzerland
Primary
Concomitant
Vertigo Other Serious 72 Female 9/25/2009 Physician Germany
Primary
Secondary
Vertigo Other Serious 72 Female 9/25/2009 Physician Germany
Primary
Secondary
Swollen Tongue Life Threatening 7/12/2009 Male 195 lb 10/9/2009 Physician Germany
Primary
Secondary
Concomitant
Tachyarrhythmia Other Serious 8/1/2009 66 Female 165 lb 10/22/2009 Physician Germany
Primary
Concomitant
Tachyarrhythmia Other Serious 8/1/2009 66 Female 165 lb 10/29/2009 Physician Germany
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/5/2009 88 Female 11/24/2009 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Pallor Hospitalization 10/27/2008 72 Male 11/25/2009 Physician Germany
Primary
Secondary
Swollen Tongue Life Threatening 7/12/2009 Male 195 lb 11/25/2009 Physician Germany
Primary
Secondary
Concomitant
Urticaria Hospitalization 11/1/2009 Male 11/27/2009 Physician Germany
Primary
Concomitant
Syncope Life Threatening 3/5/2009 89 Male 12/1/2009 Physician Germany
Primary
Concomitant
Iron Deficiency Other Serious 6/14/2009 69 Female 143 lb 1/6/2010 Physician Germany
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 4/2/2008 63 Male 162 lb 1/25/2010 Physician Switzerland
Primary
Concomitant
Hepatocellular Injury Hospitalization 12/9/2009 86 Female 2/1/2010 Physician Switzerland
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 1/20/2010 62 Female 220 lb 2/12/2010 Physician Germany
Primary
Concomitant
Pulmonary Oedema Death 11/26/2008 Male 265 lb 2/1/2010 Germany
Primary
Concomitant
Muscle Spasms Life Threatening 12/1/2009 70 Male 192 lb 2/23/2010 Germany
Primary
Concomitant
General Physical Health Deterioration Hospitalization 6/29/2009 Female 172 lb 3/10/2010 Physician Germany
Primary
Concomitant
Renal Failure Acute Other Serious Female 3/15/2010 Physician Germany
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 6/1/2006 65 Female 3/19/2010 Physician Germany
Primary
Secondary
Myocardial Infarction Other Serious 3/7/2010 53 Male 3/31/2010 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 12/1/2009 72 Male 4/9/2010 Consumer Germany
Primary
Concomitant
Oedema Peripheral Other Serious 2/8/2010 77 Female 205 lb 4/21/2010 Physician Germany
Primary
Concomitant
Soft Tissue Necrosis Hospitalization 2/1/2010 71 Female 213 lb 4/21/2010 Physician
Primary
Concomitant
Circulatory Collapse Hospitalization 4/9/2010 81 Female 5/3/2010 Physician Switzerland
Primary
Secondary
Concomitant
Somnolence Hospitalization 2/21/2010 49 Female 192 lb 5/10/2010 Physician Germany
Primary
Concomitant
Interacting
Tachycardia Hospitalization 4/20/2010 70 Male 5/11/2010 Physician Germany
Primary
Concomitant
Personality Change Other Serious 79 Female 159 lb 5/21/2010 Pharmacist Germany
Primary
Concomitant
Pulmonary Haemorrhage Other Serious 7/11/2007 79 Male 124 lb 6/1/2010 Physician Germany
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 4/11/2010 82 Female 218 lb 6/2/2010 Pharmacist
Primary
Secondary
Concomitant
Microcytic Anaemia 70 Male 6/3/2010 Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 4/2/2010 61 Male 218 lb 6/15/2010 Physician Germany
Primary
Concomitant
Mixed Liver Injury Hospitalization 4/22/2010 73 Female 132 lb 6/15/2010 Other Health Professional Switzerland
Primary
Concomitant
Interacting
International Normalised Ratio Increased Other Serious 4/27/2010 6/17/2010 Physician Italy
Primary
Secondary
Concomitant
Spinal Fracture Hospitalization 80 Female 198 lb 6/18/2010
Primary
Concomitant
Somnolence Hospitalization 9/18/2008 83 Male 6/18/2010 Physician Germany
Primary
Secondary
Vomiting Hospitalization 4/22/2010 82 Male 161 lb 6/21/2010 Physician Germany
Primary
Concomitant
Meningioma Hospitalization 3/28/2010 67 Male 220 lb 7/1/2010 Physician Germany
Primary
Concomitant
Personality Change Other Serious 79 Female 159 lb 7/2/2010 Pharmacist Germany
Primary
Concomitant
Blood Creatinine Increased Other Serious 6/17/2010 71 Male 176 lb 7/13/2010 Physician Germany
Primary
Concomitant
Prothrombin Time Prolonged Other Serious Male 7/13/2010 Consumer Germany
Primary
Concomitant
Meningioma Hospitalization 3/28/2010 67 Male 220 lb 7/13/2010 Physician Germany
Primary
Concomitant
Ejection Fraction Decreased Other Serious 1/22/2010 67 Male 163 lb 7/22/2010 Physician Germany
Primary
Secondary
Concomitant
Microcytic Anaemia Life Threatening 1/1/2009 70 Male 192 lb 7/22/2010 Germany
Primary
Concomitant
Skin Ulcer Hospitalization 6/23/2010 85 Female 203 lb 7/28/2010 Physician Germany
Primary
Concomitant
Pneumonia Other Serious 7/1/2010 70 Male 278 lb 7/29/2010 Physician Germany
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 1/1/2010 64 Male 176 lb 8/2/2010 Physician Germany
Primary
Concomitant
Renal Failure Other Serious 4/30/2010 Male 8/4/2010 Physician Switzerland
Primary
Concomitant
Vomiting Hospitalization 7/1/2010 79 Female 157 lb 8/9/2010 Physician Switzerland
Primary
Secondary
Concomitant
Hepatitis Other Serious 6/29/2010 81 Female 110 lb 8/25/2010 Physician Germany
Primary
Concomitant
Sudden Cardiac Death Hospitalization 1/3/2010 77 Male 8/30/2010 Physician Germany
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 7/20/2010 50 Male 8/31/2010 Other Health Professional Germany
Primary
Concomitant
Muscle Spasms Life Threatening 1/1/2009 70 Male 192 lb 9/1/2010 Physician Germany
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 7/20/2010 50 Male 9/20/2010 Other Health Professional Germany
Primary
Concomitant
Somatoform Disorder Hospitalization 3/1/2009 75 Male 10/1/2010 Pharmacist Switzerland
Primary
Secondary
Concomitant
Dyspnoea Other Serious 6/15/2010 83 Female 11/8/2010 Physician Germany
Primary
Concomitant
Peripheral Arterial Occlusive Disease Death 10/22/2010 66 Male 11/18/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Malaise Hospitalization 11/19/2010 70 Male 175 lb 12/17/2010 Physician Germany
Primary
Concomitant
Syncope Hospitalization 3/1/2010 12/23/2010 Consumer Germany
Primary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 11/30/2010 75 Male 12/17/2010 Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 3/1/2010 1/6/2011 Consumer Germany
Primary
Concomitant
Pneumonia Death 7/19/2009 79 Female 161 lb 1/11/2011 Physician Germany
Primary
Concomitant
Hypoxia Hospitalization 11/19/2010 70 Male 175 lb 2/7/2011 Physician Germany
Primary
Concomitant
Renal Failure Other Serious 11/11/2010 87 Female 170 lb 2/15/2011 Consumer Germany
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 11/11/2010 87 Female 170 lb 2/22/2011 Consumer Germany
Primary
Secondary
Concomitant
Cardiac Failure Death 10/31/2010 72 Male 2/23/2011 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Other Serious 1/18/2011 82 Female 149 lb 2/24/2011 Physician Germany
Primary
Concomitant
Dyspnoea Hospitalization 11/1/2007 66 Male 134 lb 3/3/2011 Physician Germany
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Other Serious 1/1/2011 74 Male 3/22/2011 Consumer Germany
Primary
Secondary
Concomitant
Ureteric Haemorrhage Other Serious 1/1/2011 74 Male 4/20/2011 Consumer Germany
Primary
Secondary
Concomitant
Renal Haemorrhage Other Serious 1/1/2011 74 Male 4/22/2011 Consumer Germany
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 2/25/2011 75 Male 185 lb 5/16/2011 Physician Germany
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Disability 11/30/2010 75 Male 201 lb 5/16/2011 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 10/30/2008 74 Male 265 lb 5/11/2011 Other Health Professional Germany
Primary
Concomitant

Drug Data