Marcumar combined with Metoprolol Succinate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ureteric Obstruction Hospitalization 2/23/2006 77 Male 172 lb 3/10/2006 Physician Switzerland
Primary
Concomitant
Intermittent Claudication Other Serious Male 4/5/2006 Germany
Primary
Secondary
Concomitant
Syncope Life Threatening 6/1/2006 72 Male 168 lb 10/30/2006 Physician Germany
Primary
Secondary
Concomitant
Vision Blurred Other Serious 9/1/2006 78 Female 11/14/2006 Other Health Professional Germany
Primary
Concomitant
Visual Disturbance Other Serious 9/1/2006 78 Female 11/30/2006 Germany
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/5/2006 72 Female 12/20/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 12/12/2005 78 Female 130 lb 2/22/2007 Physician Germany
Primary
Concomitant
Orthopnoea Hospitalization 1/1/2007 62 Male 159 lb 3/7/2007 Physician Switzerland
Primary
Concomitant
Thrombosis Other Serious 1/1/2007 82 Female 121 lb 4/6/2007 Physician Germany
Primary
Concomitant
Thrombosis Other Serious 3/1/2007 82 Female 121 lb 5/1/2007 Physician Germany
Primary
Concomitant
Psychotic Disorder Other Serious 5/1/2007 Female 6/1/2007 Physician Germany
Primary
Concomitant
Shunt Thrombosis Hospitalization 10/11/2006 Female 6/1/2007 Physician Germany
Primary
Concomitant
Sunburn Other Serious 1/1/2005 Male 6/6/2007 Other Health Professional Germany
Primary
Concomitant
Haematuria Other Serious 1/1/2007 Male 220 lb 6/7/2007 Physician Germany
Primary
Secondary
Concomitant
Shunt Thrombosis Hospitalization 10/11/2006 Female 6/25/2007 Physician Germany
Primary
Concomitant
Anaemia Other Serious 1/16/2007 Male 7/2/2007 Physician Germany
Primary
Concomitant
Anaemia Other Serious 1/16/2007 Male 7/16/2007 Physician Germany
Primary
Concomitant
Rheumatoid Factor Increased Other Serious 6/8/2007 61 Female 7/25/2007 Consumer Germany
Primary
Concomitant
Liver Disorder Death 5/30/2007 86 Female 8/1/2007 Other Health Professional Switzerland
Primary
Concomitant
Anaemia Other Serious 1/16/2007 Male 8/1/2007 Physician Germany
Primary
Concomitant
General Physical Health Deterioration Hospitalization 3/6/2006 62 Male 207 lb 8/1/2007 Physician Germany
Primary
Concomitant
Vomiting Other Serious 1/1/2007 60 Female 8/15/2007 Consumer Germany
Primary
Concomitant
Pyrexia Other Serious 7/1/2007 75 Female 8/17/2007 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 7/1/2007 75 Female 8/17/2007 Physician Germany
Primary
Concomitant
Transaminases Increased Other Serious 5/1/2007 76 Male 8/22/2007 Physician Germany
Primary
Secondary
Concomitant
Orthopnoea Hospitalization 1/1/2007 62 Male 159 lb 8/31/2007 Physician Switzerland
Primary
Concomitant
Anaemia Other Serious 1/16/2007 Male 9/7/2007 Physician Germany
Primary
Secondary
Concomitant
Liver Disorder Other Serious 7/27/2006 Female 9/28/2007 Other Health Professional Germany
Primary
Concomitant
Spinal Haematoma Hospitalization 6/28/2007 80 Female 9/25/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Rash Hospitalization 8/22/2007 63 Female 11/27/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 69 Female 154 lb 12/27/2007 Physician Germany
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 8/28/2007 63 Female 1/3/2008 Pharmacist Germany
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 8/31/2007 Male 2/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 12/15/2004 59 Male 3/7/2008 Physician Germany
Primary
Secondary
Pulmonary Embolism Hospitalization 2/29/2008 70 Male 3/19/2008 Pharmacist Germany
Primary
Concomitant
Renal Failure Hospitalization 1/26/2008 86 Male 4/7/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Colour Blindness Disability 1/1/2008 Female 5/8/2008 Physician Germany
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2008 77 Female 176 lb 7/28/2008 Physician Germany
Primary
Concomitant
Tachycardia Hospitalization 7/15/2007 Female 8/6/2008 Physician Germany
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/29/2008 Male 10/8/2008 Pharmacist Germany
Primary
Concomitant
Anaemia Hospitalization 5/15/2008 1/15/2009 Other Health Professional Germany
Primary
Concomitant
Spinal Fracture Hospitalization 9/20/2008 66 Female 2/17/2009 Physician Germany
Primary
Concomitant
Suicide Attempt Hospitalization 4/18/2009 Male 258 lb 4/24/2009 Other Health Professional Germany
Primary
Secondary
Atrioventricular Block First Degree Hospitalization 9/1/2008 Male 6/10/2009 Physician Germany
Primary
Concomitant
Venous Thrombosis Limb Other Serious 5/1/2009 Male 6/25/2009 Physician Germany
Primary
Concomitant
Arrhythmia Death 5/29/2009 Male 6/29/2009 Physician Netherlands
Primary
Secondary
Concomitant
Suicide Attempt Other Serious Male 154 lb 6/30/2009 Physician
Primary
Secondary
Drug Intolerance Hospitalization 6/14/2009 25 7/1/2009 Physician Germany
Primary
Secondary
Concomitant
Intentional Overdose Hospitalization 4/29/2009 Male 154 lb 7/2/2009 Physician Germany
Primary
Secondary
International Normalised Ratio Increased Required Intervention 5/26/2009 77 Male 7/9/2009 Germany
Primary
Concomitant
Atrial Fibrillation Other Serious 1/18/2010 2/19/2010 Physician Germany
Primary
Concomitant
Renal Failure Acute Other Serious Female 3/15/2010 Physician Germany
Primary
Concomitant
Polyuria Other Serious 2/28/2010 73 Male 198 lb 3/26/2010 Physician Germany
Primary
Concomitant
Ventricular Flutter Life Threatening 11/25/2009 76 Male 4/9/2010 Physician Switzerland
Primary
Concomitant
Pleural Effusion Hospitalization 5/15/2009 Female 141 lb 4/12/2010 Physician Germany
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2010 Male 176 lb 4/30/2010 Physician Germany
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 3/6/2010 76 Male 5/5/2010 Physician Switzerland
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 1/1/2010 71 Female 165 lb 5/14/2010 Physician Germany
Primary
Secondary
Concomitant
Ventricular Flutter Life Threatening 11/25/2009 76 Male 5/21/2010 Physician Switzerland
Primary
Concomitant
Heart Rate Increased Other Serious 4/1/2010 75 Female 5/21/2010 Consumer Germany
Primary
Concomitant
Jejunal Ulcer Hospitalization 3/2/2010 68 Male 5/26/2010 Consumer United Kingdom
Primary
Concomitant
Ventricular Flutter Life Threatening 11/25/2009 76 Male 5/28/2010 Physician Switzerland
Primary
Concomitant
Heart Rate Increased Other Serious 1/1/2010 Female 196 lb 6/1/2010 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 1/1/2010 71 Female 165 lb 6/4/2010 Physician Germany
Primary
Secondary
Concomitant
Mixed Liver Injury Hospitalization 4/22/2010 73 Female 132 lb 6/15/2010 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Spinal Column Injury Other Serious 1/1/2010 Female 196 lb 7/6/2010 Physician Germany
Primary
Concomitant
Syncope Other Serious Male 7/7/2010 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 7/1/2010 79 Female 157 lb 8/9/2010 Physician Switzerland
Primary
Secondary
Concomitant
Syncope Other Serious Male 8/16/2010 Physician Germany
Primary
Concomitant
Ventricular Tachycardia Other Serious 5/14/2010 50 Male 8/18/2010 Physician Germany
Primary
Concomitant
Cachexia Death 77 Female 9/14/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Soft Tissue Infection Other Serious 6/1/2010 87 Female 9/17/2010 Physician Germany
Primary
Concomitant
Pain Life Threatening 5/9/2010 79 Male 205 lb 9/22/2010 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 6/25/2010 74 Male 154 lb 9/27/2010 Physician Germany
Primary
Concomitant
Syncope Hospitalization 3/1/2009 75 Male 9/30/2010 Physician Switzerland
Primary
Secondary
Concomitant
Syncope Hospitalization 3/1/2009 75 Male 163 lb 10/1/2010 Pharmacist Switzerland
Primary
Concomitant
Interacting
Somatoform Disorder Hospitalization 3/1/2009 75 Male 10/1/2010 Pharmacist Switzerland
Primary
Secondary
Concomitant
Visual Impairment Disability 9/12/2010 75 Female 159 lb 10/14/2010 Physician Germany
Primary
Concomitant
Transferrin Saturation Decreased 7/7/2010 Female 10/22/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 6/18/2010 84 Female 10/22/2010 Physician Germany
Primary
Concomitant
Prothrombin Level Decreased Life Threatening 10/6/2010 80 Female 10/18/2010 Physician Germany
Primary
Concomitant
Hepatocellular Injury Hospitalization 9/8/2010 65 Male 150 lb 10/28/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Life Threatening 10/6/2010 80 Female 10/29/2010 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 1/1/2010 Female 196 lb 11/9/2010 Physician Germany
Primary
Concomitant
Prothrombin Time Prolonged Life Threatening 10/6/2010 80 Female 11/10/2010 Physician Germany
Primary
Concomitant
Transaminases Increased Life Threatening 6/1/2010 69 Male 183 lb 11/24/2010 Physician Germany
Primary
Concomitant
Death Death 9/9/2010 83 Male 179 lb 11/24/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Death Death 9/9/2010 83 Male 179 lb 11/30/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 9/14/2010 73 Female 205 lb 12/16/2010 Physician United States
Primary
Concomitant
Interacting
Ejection Fraction Decreased Other Serious 5/1/2010 49 Male 165 lb 12/28/2010 Physician Germany
Primary
Concomitant
Renal Failure Hospitalization 9/10/2010 72 Male 12/16/2010 Germany
Primary
Concomitant
Drug Ineffective Other Serious 11/11/2010 77 Male 143 lb 1/26/2011 Physician Germany
Primary
Concomitant
Blood Creatinine Increased Hospitalization 8/27/2010 56 Male 258 lb 1/26/2011 Physician Germany
Primary
Concomitant
Thrombocytopenic Purpura 12/15/2010 82 Female 132 lb 1/28/2011 Physician Germany
Primary
Concomitant
Blood Creatinine Increased Hospitalization 8/27/2010 56 Male 254 lb 2/15/2011 Physician Germany
Primary
Concomitant
Off Label Use 12/15/2010 82 Female 132 lb 2/18/2011 Physician Germany
Primary
Concomitant
Erythema Multiforme Hospitalization 12/1/2010 77 Male 2/10/2011 Switzerland
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 5/1/2010 49 Male 165 lb 3/7/2011 Physician Germany
Primary
Concomitant
Diverticular Perforation Hospitalization 9/15/2010 69 Male 216 lb 3/16/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Ejection Fraction Decreased Hospitalization 5/1/2010 49 Male 165 lb 3/29/2011 Physician Germany
Primary
Concomitant
Long Qt Syndrome Other Serious 2/26/2011 76 Female 170 lb 5/24/2011 Physician Germany
Primary
Concomitant
Sleep Disorder Other Serious 2/1/2010 Male 6/14/2011 Consumer Germany
Primary
Concomitant
Arterial Occlusive Disease Other Serious 10/15/2010 69 Female 6/14/2011 Physician Germany
Primary
Concomitant
Carotid Artery Stenosis Hospitalization 3/10/2010 67 Male 6/17/2011 Physician Germany
Primary
Concomitant
Lipase Increased Other Serious 3/19/2011 23 Male 6/20/2011 Physician Germany
Primary
Concomitant
Hepatitis Toxic Hospitalization 4/15/2011 51 Female 6/27/2011 Physician Germany
Primary
Concomitant
Hypotension Hospitalization 5/17/2011 50 Male 6/23/2011 Physician Germany
Primary
Secondary
Urinary Tract Infection Other Serious 1/1/2011 74 Female 7/22/2011 Physician Switzerland
Primary
Concomitant
Hypertriglyceridaemia Other Serious 7/22/2011 56 Male 247 lb 8/15/2011 Consumer Germany
Primary
Concomitant
Pulmonary Congestion Other Serious 11/15/2008 71 Male 8/22/2011 Physician Germany
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 4/15/2011 51 Female 8/30/2011 Physician Germany
Primary
Concomitant
Leukopenia Other Serious 8/12/2011 67 Male 187 lb 8/31/2011 Physician Germany
Primary
Secondary
Concomitant
Ileus Paralytic Death 4/27/2011 76 Male 9/14/2011 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 6/1/2011 76 Male 203 lb 9/20/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Prothrombin Time Prolonged 12/2/2010 61 Male 291 lb 9/7/2011 Physician Germany
Primary
Concomitant
Underdose Life Threatening 6/22/2011 78 Male 220 lb 9/23/2011 Physician Switzerland
Primary
Concomitant
Blood Bilirubin Increased Other Serious 1/1/2011 61 Male 187 lb 10/3/2011 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Other Serious 7/22/2011 56 Male 247 lb 10/3/2011 Consumer Germany
Primary
Concomitant
Laceration Hospitalization 8/31/2011 78 Female 154 lb 10/11/2011 Physician Germany
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 3/28/2011 67 Male 212 lb 10/20/2011 Physician Germany
Primary
Concomitant
Haemoglobin Decreased Hospitalization 8/1/2011 10/24/2011 Physician Germany
Primary
Concomitant
Cardiac Pacemaker Insertion Hospitalization 9/1/2011 Female 10/25/2011 Physician Switzerland
Primary
Secondary
Concomitant
Cardiac Pacemaker Insertion Hospitalization 9/1/2011 Female 11/28/2011 Physician Switzerland
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/25/2011 12/23/2011 Other Health Professional Germany
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/4/2011 12/28/2011 Other Health Professional Germany
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/1/2011 71 Male 163 lb 1/20/2012 Consumer Brazil
Primary
Secondary
Concomitant
Gastroenteritis Disability 10/1/2011 60 Female 139 lb 2/2/2012 Pharmacist Germany
Primary
Concomitant
Weight Decreased Other Serious 2/1/2011 84 Female 2/24/2012 Other Health Professional Germany
Primary
Concomitant
Respiratory Tract Infection Hospitalization 12/27/2011 44 Male 265 lb 2/28/2012 Other Health Professional Germany
Primary
Concomitant
Haematotoxicity Disability Female 4/3/2012 Physician Belgium
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 2/21/2012 73 Male 4/10/2012 Germany
Primary
Concomitant
Hepatitis Acute Hospitalization 12/4/2007 84 Male 4/24/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Asthenia Other Serious 1/4/2012 78 Male 4/25/2012 Consumer United States
Primary
Secondary
Concomitant
Hepatitis Acute Other Serious 12/4/2007 84 Male 163 lb 4/26/2012 Physician Germany
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 2/1/2012 Female 5/14/2012 Consumer Germany
Primary
Concomitant
Ischaemic Cerebral Infarction Hospitalization 11/1/2010 66 Female 5/17/2012 Physician Germany
Primary
Concomitant
Nausea Other Serious 8/22/2011 71 Male 207 lb 5/23/2012 Other Health Professional Germany
Primary
Concomitant
Oedema Hospitalization 4/1/2012 80 Male 209 lb 6/4/2012 Physician Germany
Primary
Concomitant
Hepatic Neoplasm Malignant Death 4/1/2012 80 Male 209 lb 6/7/2012 Physician Germany
Primary
Concomitant
Cholestasis Life Threatening 12/13/2011 87 Female 154 lb 6/25/2012 Physician Germany
Primary
Secondary
Concomitant
Disorientation Other Serious 4/30/2012 77 Female 165 lb 7/26/2012 Physician Germany
Primary
Concomitant
Gastric Ulcer Hospitalization 7/9/2007 53 Male 8/15/2012 Physician Germany
Primary
Concomitant
Fatigue Hospitalization 4/1/2012 80 Male 209 lb 8/20/2012 Physician Germany
Primary
Concomitant
Cytomegalovirus Infection Other Serious 12/1/2009 71 Male 190 lb 8/21/2012 Consumer Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/1/2012 Male 8/22/2012 Consumer Germany
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 1/11/2010 71 Male 190 lb 12/7/2012 Other Health Professional De
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 7/16/2012 Male 12/12/2012 Consumer De
Primary
Concomitant
Pain Hospitalization 5/15/2013 65 Female 180 lb 6/20/2013 Physician Country Not Specified
Primary
Concomitant
Respiratory Failure Hospitalization 2013 Male 7/16/2013 Other Health Professional De
Primary
Concomitant
Pulseless Electrical Activity Death 3/22/2013 74 Female 8/7/2013 Other Health Professional De
Primary
Concomitant

Drug Data