Mannitol combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Propofol Infusion Syndrome Death 1/8/2006 Female 77 lb 1/27/2006 Pharmacist United States
Primary
Concomitant
Ventricular Arrhythmia Hospitalization 17 Male 2/22/2006 Other Health Professional Netherlands
Primary
Concomitant
Therapy Non-responder Hospitalization 44 Male 2/23/2006 Other Health Professional Netherlands
Primary
Concomitant
Rhabdomyolysis Other Serious 15 Male 2/24/2006 Other Health Professional Netherlands
Primary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 15 Male 3/10/2006 Other Health Professional Netherlands
Primary
Concomitant
Ventricular Tachycardia Other Serious 5/1/2001 31 Male 183 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Propofol Infusion Syndrome Required Intervention 15 Male 3/30/2006 Physician Canada
Primary
Concomitant
Rhabdomyolysis Life Threatening 6/13/2005 49 Female 265 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Rash Pustular Hospitalization 6/19/2006 45 Female 8/4/2006 Other Health Professional France
Primary
Secondary
Concomitant
Rash Pustular Hospitalization 6/19/2006 45 Female 8/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/28/2006 64 Female 143 lb 9/27/2006 Physician Germany
Primary
Concomitant
Blood Creatinine Increased Life Threatening 12/14/2005 77 Male 50 lb 8/29/2006 Physician United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 21 Male 174 lb 10/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 39 Male 187 lb 4/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Other Serious 9/30/2006 62 Female 141 lb 6/14/2007 Physician Germany
Primary
Concomitant
Tachycardia Other Serious 16 Male 8/15/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Death 29 Female 9/13/2007 Physician United States
Primary
Concomitant
Thrombosis Required Intervention 9/6/2007 56 Female 10/1/2007 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 3/22/2007 69 Male 111 lb 11/21/2007 Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 52 Female 1/18/2008 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 3/22/2007 69 Male 111 lb 1/30/2008 Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/16/2005 36 Female 2/13/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/16/2005 36 Female 2/22/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Small For Dates Baby Required Intervention Male 3 lb 5/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/7/2008 49 Female 143 lb 6/17/2008 Physician Germany
Primary
Secondary
Concomitant
Dermatitis Exfoliative Other Serious 4/14/2008 31 Female 6/25/2008 Physician Poland
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 38 Male 8/7/2008
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Pyrexia Hospitalization 8/28/2008 9/16/2008 Pharmacist United States
Primary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/28/2008 67 Female 121 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/28/2008 67 Female 121 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Tachyarrhythmia Other Serious 38 Male 12/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tachyarrhythmia Other Serious 38 Male 12/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Propofol Infusion Syndrome Death 17 3/16/2009 Physician Netherlands
Primary
Concomitant
Propofol Infusion Syndrome Hospitalization 17 Male 3/23/2009 Physician Netherlands
Primary
Concomitant
Ventricular Tachycardia Required Intervention 38 Male 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tachyarrhythmia Required Intervention 38 Male 3/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Metabolic Alkalosis Other Serious 64 Female 117 lb 4/14/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Metabolic Alkalosis Other Serious 64 Female 117 lb 5/27/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 38 Male 8/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Meningitis Pneumococcal Hospitalization 9/9/2009 Female 157 lb 12/22/2009 Physician Italy
Primary
Secondary
Concomitant
Post Procedural Complication Required Intervention 11/13/2009 47 Male 174 lb 11/16/2009 Pharmacist United States
Primary
Concomitant
Angle Closure Glaucoma Other Serious 5/17/2009 56 Female 134 lb 12/21/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 11/27/2007 58 Female 123 lb 2/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2008 71 Female 2/3/2010 Other Health Professional United States
Primary
Concomitant
Osmotic Demyelination Syndrome Hospitalization 6/24/2009 Female 112 lb 2/8/2010 Physician Japan
Primary
Concomitant
Osmotic Demyelination Syndrome Hospitalization 6/24/2009 Female 112 lb 2/15/2010 Physician Japan
Primary
Concomitant
Hypotension Hospitalization 3/1/2010 51 Male 4/2/2010 Australia
Primary
Secondary
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 1/21/2009 45 Male 5/12/2010 Physician Germany
Primary
Secondary
Concomitant
Serratia Infection Other Serious 1/1/2008 64 Male 165 lb 9/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2008 71 Female 9/20/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 11/22/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/20/2007 69 Female 139 lb 12/2/2010 Other Health Professional United States
Primary
Concomitant
Lactic Acidosis Other Serious 57 Male 176 lb 12/6/2010 Physician Spain
Primary
Concomitant
Overdose Hospitalization 10/28/2010 1 Male 12/28/2010 France
Primary
Secondary
Concomitant
Klebsiella Sepsis Other Serious 4/15/2000 73 Male 160 lb 2/28/2011 Other Health Professional United States
Primary
Concomitant
Depression Death 4/15/2000 73 Male 160 lb 2/28/2011 Consumer United States
Primary
Concomitant
Pain Death 12/9/2004 62 Female 342 lb 2/28/2011 Consumer United States
Primary
Concomitant
Anhedonia Other Serious 12/9/2004 62 Female 342 lb 2/28/2011 Consumer United States
Primary
Concomitant
Anxiety Death 10/8/2004 45 Female 110 lb 3/10/2011 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 10/8/2004 45 Female 110 lb 3/10/2011 Consumer United States
Primary
Concomitant
Emotional Distress Other Serious 1/1/2004 77 Female 116 lb 3/15/2011 Lawyer United States
Primary
Concomitant
Anxiety Other Serious 1/1/2004 77 Female 116 lb 3/15/2011 Lawyer United States
Primary
Concomitant
Asthenia Death 1/6/2004 78 Male 165 lb 3/17/2011 Lawyer United States
Primary
Concomitant
Multi-organ Failure Death 12/17/2002 79 Female 244 lb 3/18/2011 Lawyer United States
Primary
Concomitant
Pain Death 2/1/2004 76 Male 185 lb 3/22/2011 Lawyer United States
Primary
Concomitant
Pain Hospitalization 1/16/2004 75 Female 165 lb 3/22/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 10/21/2003 58 Female 180 lb 3/23/2011 Lawyer United States
Primary
Concomitant
Injury Other Serious 10/21/2003 58 Female 180 lb 3/23/2011 Other Health Professional United States
Primary
Concomitant
Injury Hospitalization 8/12/2003 63 Male 84 lb 3/24/2011 Lawyer United States
Primary
Concomitant
Multi-organ Failure Other Serious 1/1/2000 54 Male 224 lb 3/24/2011 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 9/30/2005 82 Female 120 lb 3/29/2011 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Other Serious 7/12/2006 64 Female 190 lb 3/29/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Hospitalization 9/30/2005 82 Female 120 lb 3/29/2011 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 7/12/2006 64 Female 190 lb 3/29/2011 Consumer United States
Primary
Concomitant
Pain Other Serious 11/1/2006 79 Female 190 lb 3/30/2011 Lawyer United States
Primary
Concomitant
Injury Other Serious 1/6/2004 78 Male 165 lb 3/30/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Other Serious 11/4/2006 74 Male 165 lb 3/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Death 9/7/1998 80 Male 174 lb 4/5/2011 Consumer United States
Primary
Concomitant
Stress Other Serious 9/7/1998 80 Male 174 lb 4/5/2011 Other Health Professional United States
Primary
Concomitant
Emotional Distress Hospitalization 3/1/2006 48 Male 220 lb 4/6/2011 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 1/1/2007 65 Male 183 lb 4/6/2011 Lawyer United States
Primary
Concomitant
Depression Other Serious 1/1/2003 44 Male 258 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Injury Death 1/1/2003 44 Male 258 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Other Serious 2/17/2006 52 Female 110 lb 4/8/2011 Lawyer United States
Primary
Concomitant
Fear Of Death Other Serious 11/11/2004 65 Male 185 lb 4/13/2011 Consumer United States
Primary
Concomitant
Renal Injury Other Serious 1/1/2007 71 Male 253 lb 4/13/2011 Lawyer United States
Primary
Concomitant
Stress Hospitalization 1/1/2002 89 Female 110 lb 4/14/2011 Lawyer United States
Primary
Secondary
Concomitant
Pain Other Serious Male 4/15/2011 Lawyer United States
Primary
Concomitant
Nervousness Other Serious 1/3/2007 46 Male 224 lb 4/15/2011 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 8/9/2004 74 Male 183 lb 4/15/2011 Lawyer United States
Primary
Concomitant
Injury Other Serious 1/2/2004 45 Male 204 lb 4/19/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Death 12/1/2006 67 Male 161 lb 4/20/2011 Lawyer United States
Primary
Concomitant
Anhedonia Hospitalization 53 Female 160 lb 4/21/2011 Lawyer United States
Primary
Concomitant
Anhedonia Hospitalization 11/12/2005 75 Female 168 lb 4/23/2011 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Other Serious 72 Male 212 lb 4/25/2011 Lawyer United States
Primary
Concomitant
Injury Other Serious 1/1/1980 69 Male 266 lb 4/25/2011 Consumer United States
Primary
Concomitant
Renal Injury Other Serious 3/1/2004 67 Female 265 lb 4/26/2011 Lawyer United States
Primary
Concomitant
Anxiety Hospitalization 1/6/2004 78 Male 165 lb 4/27/2011 Other Health Professional United States
Primary
Concomitant
Renal Disorder Death 10/25/2005 72 Male 190 lb 4/28/2011 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Other Serious 70 Male 198 lb 4/28/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 10/2/2008 53 Male 222 lb 5/2/2011 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 6/29/2003 59 Male 221 lb 5/2/2011 Other Health Professional United States
Primary
Concomitant
Stress Hospitalization 1/1/2004 81 Female 116 lb 5/5/2011 Lawyer United States
Primary
Concomitant
Fear Other Serious 12/2/2005 74 Male 159 lb 5/6/2011 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 10/8/2005 68 Female 148 lb 5/9/2011 Physician United States
Primary
Concomitant
Fear Other Serious 8/8/2003 54 Male 372 lb 5/9/2011 Lawyer United States
Primary
Concomitant
Emotional Distress Other Serious 9/18/2002 77 Male 135 lb 5/10/2011 Lawyer United States
Primary
Concomitant
Renal Impairment Other Serious 72 Male 212 lb 5/11/2011 Lawyer United States
Primary
Concomitant
Pain Other Serious 9/11/2005 62 Male 280 lb 5/11/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Other Serious 6/17/2003 79 Female 198 lb 5/12/2011 Consumer United States
Primary
Concomitant
Anxiety Other Serious 1/1/2004 81 Female 116 lb 5/13/2011 Lawyer United States
Primary
Concomitant
Death Other Serious 2/1/2004 76 Male 185 lb 5/13/2011 Lawyer United States
Primary
Concomitant
Fear Of Death Other Serious 10/30/2004 42 Female 180 lb 5/13/2011 Other Health Professional United States
Primary
Concomitant
Injury Other Serious 2/16/2004 78 Female 169 lb 5/16/2011 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 3/17/2005 65 Female 157 lb 5/17/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 9/11/2005 62 Male 280 lb 5/17/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 29 Male 190 lb 5/17/2011 Lawyer United States
Primary
Concomitant
Pain Other Serious 48 Female 118 lb 5/18/2011 Other Health Professional United States
Primary
Concomitant
Depression Other Serious 1/1/2007 73 Male 151 lb 5/18/2011 Lawyer United States
Primary
Concomitant
Unevaluable Event Death 2/27/2005 76 Female 160 lb 5/19/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Other Serious 70 Male 198 lb 5/19/2011 Other Health Professional United States
Primary
Concomitant
Multi-organ Failure Death 11/19/2001 59 Female 259 lb 5/19/2011 Other Health Professional United States
Primary
Concomitant
Bradycardia Hospitalization 42 Male 187 lb 5/23/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pain Death 6/17/2003 79 Female 198 lb 5/21/2011 Lawyer United States
Primary
Concomitant
Injury Other Serious 51 Female 238 lb 5/21/2011 Consumer United States
Primary
Concomitant
Injury Other Serious Male 176 lb 5/23/2011 Lawyer United States
Primary
Concomitant
Anhedonia Other Serious 8/12/2005 67 Male 185 lb 5/21/2011 Physician United States
Primary
Concomitant
Unevaluable Event Other Serious 7/3/2000 67 Male 201 lb 5/21/2011 Other Health Professional United States
Primary
Concomitant
Ileus Other Serious 10/6/2006 51 Female 247 lb 5/24/2011 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 8/29/2008 53 Male 154 lb 5/24/2011 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Other Serious 9/6/2005 58 Female 220 lb 5/24/2011 Lawyer United States
Primary
Concomitant
Pleural Effusion Death 1/1/2007 73 Male 151 lb 5/24/2011 Lawyer United States
Primary
Concomitant
Depression Hospitalization 9/1/2004 57 Female 235 lb 5/25/2011 Other Health Professional United States
Primary
Concomitant
Emotional Distress Other Serious 1 11 lb 5/25/2011 Lawyer United States
Primary
Concomitant
Unevaluable Event Other Serious 5/19/2005 58 Male 249 lb 5/26/2011 Lawyer United States
Primary
Concomitant
Diarrhoea Life Threatening 7/25/2009 70 Male 5/31/2011 Pharmacist United States
Primary
Concomitant
Injury Other Serious 51 Female 5/31/2011 Lawyer United States
Primary
Concomitant
Emotional Distress Hospitalization 4/2/2005 60 Male 288 lb 5/31/2011 Consumer United States
Primary
Concomitant
Multi-organ Failure Other Serious 9/17/2003 70 Female 207 lb 6/1/2011 Lawyer United States
Primary
Concomitant
Anxiety Hospitalization 10/16/2006 64 Male 186 lb 6/3/2011 Lawyer United States
Primary
Concomitant
Unevaluable Event Other Serious 8/24/2005 82 Male 150 lb 6/7/2011 Other Health Professional United States
Primary
Concomitant
Nervousness Hospitalization 10/11/2006 74 Female 172 lb 6/8/2011 Other Health Professional United States
Primary
Concomitant

Drug Data