Loxoprofen Sodium combined with Magnesium Oxide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Liver Disease Life Threatening 1/19/2006 64 Male 3/16/2006 United States
Primary
Secondary
Concomitant
Weight Increased Life Threatening 1/19/2006 64 Male 4/25/2006 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/8/2006 70 Female 5/4/2006 Physician Japan
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 4/13/2006 51 Female 132 lb 5/10/2006 Physician Japan
Primary
Concomitant
Pyelonephritis Hospitalization 4/13/2006 51 Female 132 lb 5/30/2006 Physician Japan
Primary
Concomitant
Weight Increased Hospitalization 5/30/2006 35 Female 8/1/2006 Physician Japan
Primary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/11/2006 Physician Japan
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Life Threatening 7/10/2006 69 Female 90 lb 8/14/2006 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/22/2006 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 5/22/2006 35 Female 113 lb 8/28/2006 Physician Japan
Primary
Concomitant
Tubulointerstitial Nephritis Life Threatening 7/5/2006 69 Female 90 lb 9/5/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/22/2006 35 Female 113 lb 9/25/2006 Physician Japan
Primary
Concomitant
Generalised Erythema Hospitalization 8/1/2006 86 Female 10/2/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/15/2006 58 Male 155 lb 10/17/2006 Physician Japan
Primary
Concomitant
Generalised Erythema Hospitalization 8/1/2006 86 Female 11/16/2006 Physician Japan
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 10/24/2006 76 Male 12/8/2006 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 10/31/2006 66 Female 12/11/2006 Other Health Professional Japan
Primary
Concomitant
Somnolence Hospitalization 5/2/2006 Male 115 lb 1/5/2007 Japan
Primary
Concomitant
Vomiting Hospitalization 7/15/2006 Male 155 lb 1/23/2007 Japan
Primary
Concomitant
Malaise Hospitalization 1/17/2007 Female 2/5/2007 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 2/14/2007 Male 170 lb 2/19/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 2/12/2007 Male 170 lb 2/23/2007 Other Health Professional Japan
Primary
Concomitant
Hepatitis Fulminant Other Serious 1/13/2007 Female 88 lb 2/26/2007 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 1/17/2007 Female 2/28/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatitis Fulminant Other Serious 1/13/2007 Female 88 lb 3/2/2007 Physician Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 2/12/2007 Male 170 lb 3/7/2007 Other Health Professional Japan
Primary
Concomitant
Hepatitis Fulminant Other Serious 1/13/2007 Female 88 lb 3/15/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatitis Fulminant Other Serious 1/13/2007 Female 88 lb 3/23/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/7/2007 63 Female 134 lb 5/2/2007 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 2/12/2007 Male 170 lb 5/3/2007 Other Health Professional Japan
Primary
Concomitant
Hyperglycaemia Life Threatening 2/12/2007 Male 170 lb 5/16/2007 Other Health Professional Japan
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 2/12/2007 Male 170 lb 6/7/2007 Other Health Professional Japan
Primary
Concomitant
Generalised Erythema Hospitalization 8/1/2006 86 Female 6/12/2007 Physician Japan
Primary
Concomitant
Somnolence Other Serious 8/22/2005 71 Male 6/13/2007
Primary
Secondary
Concomitant
Somnolence Other Serious 8/22/2005 71 Male 7/31/2007
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 2/12/2007 Male 170 lb 8/21/2007 Other Health Professional Japan
Primary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 9/5/2007 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/26/2007 Female 129 lb 10/15/2007 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 9/26/2007 Female 92 lb 10/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 5/30/2007 Female 10/26/2007 Other Health Professional Japan
Primary
Concomitant
Interacting
Hypoxia Hospitalization 10/22/2007 Male 101 lb 11/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Leg Amputation Other Serious 12/26/2003 Male 119 lb 11/20/2007 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/22/2007 Male 101 lb 11/29/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/22/2007 Male 101 lb 12/7/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 10/2/2007 81 Female 12/19/2007 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 10/2/2007 81 Female 12/31/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/16/2007 Male 147 lb 1/8/2008 Pharmacist Japan
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 2/12/2007 Male 170 lb 2/12/2008 Other Health Professional Japan
Primary
Concomitant
Hyperammonaemia Hospitalization 12/28/2007 Male 143 lb 2/19/2008 Japan
Primary
Secondary
Concomitant
Hyperammonaemia Hospitalization 12/28/2007 Male 143 lb 3/18/2008 Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/26/2007 Female 129 lb 4/29/2008 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 2/12/2007 Male 170 lb 5/29/2008 Other Health Professional Japan
Primary
Concomitant
Liver Disorder Hospitalization 4/23/2008 Male 6/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Prostate Cancer Death 6/5/2007 82 Male 6/27/2008 Japan
Primary
Concomitant
Prostate Cancer Death 6/5/2007 82 Male 7/18/2008 Japan
Primary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 8/11/2008 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 9/21/2006 81 Male 121 lb 9/30/2008 Other Health Professional Japan
Primary
Concomitant
Renal Failure Other Serious 1/1/2008 Male 10/13/2008 Japan
Primary
Concomitant
Haematuria Other Serious 10/2/2008 89 Female 10/16/2008 Physician Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 10/18/2008 Japan
Primary
Secondary
Concomitant
Cellulitis Hospitalization 10/1/2008 Female 102 lb 10/24/2008 Japan
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 10/27/2008 Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 10/29/2008 Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 11/3/2008 Japan
Primary
Secondary
Concomitant
Urine Output Decreased Disability 2/29/2008 64 Male 11/5/2008 Physician Japan
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 11/5/2008 Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 7/28/2008 Male 11/6/2008 Japan
Primary
Concomitant
Urine Output Decreased Disability 2/29/2008 64 Male 11/7/2008 Physician Japan
Primary
Concomitant
Cellulitis Hospitalization 10/1/2008 Female 102 lb 11/14/2008 Japan
Primary
Concomitant
White Blood Cell Count Increased Disability 2/29/2008 64 Male 11/7/2008 Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 10/22/2008 Male 192 lb 12/4/2008 Physician Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 12/14/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 7/28/2008 12/19/2008 Physician Japan
Primary
Concomitant
Urine Output Decreased Disability 2/29/2008 64 Male 12/22/2008 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Hospitalization Female 12/30/2008 Physician Japan
Primary
Secondary
Concomitant
Gastric Perforation Hospitalization 6/27/2008 Male 111 lb 1/12/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/14/2008 78 Male 1/28/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/14/2008 78 Male 2/13/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 7/22/2008 2/13/2009 Physician Japan
Primary
Concomitant
Duodenal Perforation Hospitalization 2/16/2009 Male 104 lb 3/2/2009 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 7/22/2008 3/6/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 7/22/2008 3/13/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 11/14/2008 78 Male 3/16/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Sedation Other Serious 7/29/2008 86 Female 3/30/2009 Germany
Primary
Concomitant
Vomiting Hospitalization 7/15/2006 4/20/2009 Physician Japan
Primary
Concomitant
Hepatic Failure Hospitalization Female 104 lb 5/11/2009 Physician Japan
Primary
Concomitant
Cellulitis Hospitalization 10/1/2008 Female 102 lb 5/13/2009 Japan
Primary
Concomitant
Vomiting Hospitalization 1/21/2009 Female 104 lb 5/22/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 4/21/2009 59 6/10/2009 Physician Japan
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 6/8/2009 66 Male 6/25/2009 Physician Japan
Primary
Concomitant
Hallucination Hospitalization 6/15/2009 Female 152 lb 7/2/2009 Physician Japan
Primary
Concomitant
Cellulitis Hospitalization 10/1/2008 Female 102 lb 7/8/2009 Japan
Primary
Concomitant
Hallucination Hospitalization 6/15/2009 Female 152 lb 7/14/2009 Physician Japan
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 6/8/2009 66 Male 7/23/2009 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 9/30/2008 Female 8/3/2009 Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 4/21/2009 59 8/4/2009 Physician Japan
Primary
Concomitant
Snoring Death 8/1/2009 24 8/18/2009 Japan
Primary
Secondary
Concomitant
Hallucination Hospitalization 6/15/2009 Female 152 lb 9/1/2009 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 4/29/2008 29 9/2/2009 Physician Japan
Primary
Concomitant
Cardiac Failure Death 8/1/2009 24 9/4/2009 Japan
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Life Threatening 5/19/2009 89 Male 9/11/2009 Physician Japan
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Life Threatening 5/19/2009 89 Male 9/14/2009 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Other Serious 4/29/2008 29 9/15/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 4/21/2009 59 9/17/2009 Physician Japan
Primary
Concomitant
Ovarian Cancer Other Serious 6/8/2009 Female 106 lb 9/18/2009 Physician Japan
Primary
Concomitant
Ovarian Cancer Other Serious 6/8/2009 Female 106 lb 9/24/2009 Physician Japan
Primary
Concomitant
Wrong Technique In Drug Usage Process Life Threatening 5/1/2009 89 Male 9/25/2009 Physician Japan
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Life Threatening 5/1/2009 89 Male 10/15/2009 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 8/1/2009 24 10/30/2009 Japan
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Life Threatening 5/1/2009 89 Male 11/2/2009 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 8/1/2009 24 Male 110 lb 11/5/2009 Japan
Primary
Secondary
Concomitant
Ovarian Cancer Other Serious 5/27/2009 Female 106 lb 11/13/2009 Physician Japan
Primary
Concomitant
Hallucination, Visual Other Serious 5/11/2009 Female 324 lb 11/23/2009 Physician Japan
Primary
Secondary
Concomitant
Death Death 9/22/2009 67 Male 11/30/2009 Physician Japan
Primary
Concomitant
Cardiac Failure Acute Death 8/1/2009 24 Male 110 lb 12/10/2009 Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/8/2008 61 Female 90 lb 12/11/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/8/2008 61 Female 90 lb 1/19/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Metastases To Central Nervous System Death 8/20/2009 67 Male 136 lb 1/22/2010 Physician Japan
Primary
Concomitant
Mania Hospitalization 3/1/2009 Male 170 lb 2/8/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 1/13/2010 61 Female 95 lb 2/12/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Death 8/20/2009 Female 119 lb 2/15/2010 Physician Japan
Primary
Concomitant
Urticaria Life Threatening 1/16/2008 Male 77 lb 2/19/2010 Other Health Professional Japan
Primary
Concomitant
Neuropathy Peripheral Other Serious 2/23/2009 67 Male 170 lb 2/23/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Rhinitis Allergic Life Threatening 1/16/2008 Male 77 lb 3/1/2010 Other Health Professional Japan
Primary
Concomitant
Herpes Zoster Hospitalization 1/13/2010 61 Female 95 lb 3/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 1/13/2010 61 Female 95 lb 3/22/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Ovarian Cancer Death Female 119 lb 4/2/2010 Physician Japan
Primary
Concomitant
Tongue Disorder Other Serious 4/9/2010 84 Female 5/5/2010 Consumer Japan
Primary
Concomitant
Tongue Disorder Other Serious 4/9/2010 84 Female 6/3/2010 Consumer Japan
Primary
Concomitant
Ovarian Cancer Other Serious 7/5/2009 58 Female 55 lb 7/29/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/27/2010 70 Female 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/18/2010 71 Male 8/30/2010 Physician Japan
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 8/18/2010 71 Male 9/7/2010 Physician Japan
Primary
Concomitant
Urine Output Decreased Other Serious 10/5/2010 86 Male 11/19/2010 Japan
Primary
Concomitant
Urine Output Decreased Other Serious 10/5/2010 86 Male 12/16/2010 Japan
Primary
Concomitant
Tremor Hospitalization 8/8/2010 Female 97 lb 12/24/2010 Consumer United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/29/2009 53 Female 159 lb 1/10/2011 Physician Japan
Primary
Concomitant
Herpes Zoster Hospitalization 1/13/2010 61 Female 95 lb 1/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 10/5/2010 86 Male 1/24/2011 Other Health Professional Japan
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/8/2008 61 Female 90 lb 1/26/2011 Physician Japan
Primary
Secondary
Concomitant
Disease Progression Death 2/2/2008 1/26/2011 Physician Japan
Primary
Concomitant
Thrombocytopenia Death 1/19/2011 57 Male 2/10/2011 Physician Japan
Primary
Concomitant
Infection Hospitalization 2/2/2008 2/18/2011 Physician Japan
Primary
Concomitant
Condition Aggravated Hospitalization 3/22/2007 81 Male 112 lb 3/7/2011 Physician Japan
Primary
Concomitant
Gastric Cancer Hospitalization 8/1/2010 Male 148 lb 3/16/2011 Physician Japan
Primary
Secondary
Concomitant
Colitis Ulcerative Hospitalization 1/13/2011 51 Female 115 lb 4/5/2011 Physician Japan
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Death 1/19/2011 57 Male 4/6/2011 Physician Japan
Primary
Concomitant
Erythropenia Other Serious 7/10/2009 82 Female 121 lb 5/16/2011 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/20/2011 61 Female 123 lb 5/24/2011 Physician Japan
Primary
Concomitant

Drug Data