Loxoprofen combined with Rebamipide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lung Disorder Death 8/6/2006 75 Male 125 lb 9/19/2006 Physician Japan
Primary
Concomitant
Respiratory Failure Death 8/6/2006 75 Male 125 lb 10/12/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 9/4/2006 93 Male 11/1/2007 Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 11/12/2007 67 Female 11/29/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 11/12/2007 67 Female 12/7/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Purpura Hospitalization 11/11/2007 Female 113 lb 1/7/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Purpura Hospitalization 11/11/2007 Female 113 lb 2/14/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Respiratory Rate Increased Other Serious 3/24/2008 Female 115 lb 5/13/2008 Physician Japan
Primary
Secondary
Concomitant
Suicide Attempt Death 7/11/2008 Male 7/18/2008 Japan
Primary
Concomitant
Prostatic Specific Antigen Increased Hospitalization 9/3/2006 69 Male 8/8/2008 Other Health Professional Japan
Primary
Concomitant
Prostate Cancer Death 3/11/2008 87 Male 10/8/2008 Japan
Primary
Concomitant
Hepatitis Acute Hospitalization 10/4/2008 64 Female 10/15/2008 Physician Japan
Primary
Secondary
Prothrombin Time Shortened Other Serious 6/23/2008 Female 10/31/2008 Physician Japan
Primary
Secondary
Concomitant
Prostate Cancer Death 3/11/2008 87 Male 11/7/2008 Japan
Primary
Concomitant
Prostate Cancer Death 3/11/2008 87 Male 176 lb 11/24/2008 Japan
Primary
Concomitant
Prothrombin Time Shortened Other Serious 6/23/2008 Female 12/9/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/12/2008 49 Male 1/26/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 12/12/2008 49 Male 3/12/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 12/12/2008 49 Male 5/26/2009 Physician Japan
Primary
Concomitant
Malaise Hospitalization 6/13/2009 68 8/26/2009 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 6/13/2009 68 9/16/2009 Physician Japan
Primary
Secondary
Concomitant
Swelling Face Hospitalization 6/13/2009 Female 107 lb 10/1/2009 Physician United States
Primary
Secondary
Concomitant
Malaise Hospitalization 6/13/2009 68 10/6/2009 Physician Japan
Primary
Secondary
Concomitant
Swelling Face Hospitalization 6/13/2009 Female 107 lb 10/19/2009 Physician United States
Primary
Secondary
Concomitant
Malaise Hospitalization 6/13/2009 68 Female 107 lb 12/16/2009 Physician Japan
Primary
Secondary
Concomitant
Duodenal Ulcer Perforation Hospitalization 3/14/2010 65 Female 121 lb 4/12/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 3/14/2010 65 Female 121 lb 5/6/2010 Physician Japan
Primary
Secondary
Concomitant
Restlessness Hospitalization 5/10/2010 40 Female 6/1/2010 Physician Japan
Primary
Concomitant
Ulcer Hospitalization 6/27/2007 63 Female 75 lb 6/25/2010 Physician Japan
Primary
Secondary
Concomitant
Ulcer Hospitalization 6/27/2007 63 Female 75 lb 7/27/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/25/2010 69 Male 8/20/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/25/2010 69 Male 9/27/2010 Physician Japan
Primary
Concomitant
Hyperkalaemia Other Serious 6/25/2010 69 Male 10/14/2010 Physician Japan
Primary
Concomitant
Papule Other Serious 7/30/2010 79 Female 11/10/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 7/30/2010 79 Female 12/2/2010 Physician Japan
Primary
Concomitant
Hyperkalaemia Other Serious 6/25/2010 69 Male 12/13/2010 Physician Japan
Primary
Concomitant
Hyperkalaemia Other Serious 6/25/2010 69 Male 12/30/2010 Physician Japan
Primary
Concomitant
Radiation Pneumonitis Hospitalization 55 Male 3/17/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 6/25/2010 69 Male 101 lb 4/26/2011 Physician Japan
Primary
Concomitant
Oedema Peripheral Hospitalization 11/24/2010 80 Female 84 lb 6/6/2011 Physician Japan
Primary
Secondary
Concomitant
Organising Pneumonia Other Serious 2/4/2009 64 Female 108 lb 6/28/2011 Physician Japan
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 2/4/2010 64 Female 108 lb 6/29/2011 Physician Japan
Primary
Concomitant
Prostate Cancer Other Serious 6/23/2011 81 Male 172 lb 7/1/2011 Physician Japan
Primary
Concomitant
Hypertension Death 8/11/2010 65 Female 97 lb 7/6/2011 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 6/25/2010 69 Male 101 lb 7/12/2011 Physician Japan
Primary
Concomitant
Prostate Cancer Other Serious 6/23/2011 81 Male 172 lb 7/13/2011 Physician Japan
Primary
Concomitant
Insomnia Hospitalization 5/10/2011 79 Male 8/2/2011 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 3/14/2011 78 Male 112 lb 8/9/2011 Physician Japan
Primary
Concomitant
Cardiomegaly Other Serious 10/13/2010 78 Male 126 lb 8/18/2011 Physician Japan
Primary
Concomitant
Dermatitis Acneiform Death 8/11/2010 65 Female 97 lb 8/22/2011 Physician Japan
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 6/23/2011 81 Male 172 lb 8/26/2011 Physician Japan
Primary
Concomitant
Prostatic Specific Antigen Increased 6/23/2011 81 Male 172 lb 9/6/2011 Physician Japan
Primary
Concomitant
Malaise Other Serious 8/2/2011 67 Male 141 lb 9/5/2011 Physician Japan
Primary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 8/2/2011 67 Male 141 lb 9/13/2011 Physician Japan
Primary
Concomitant
Dermatitis Acneiform Death 8/11/2010 65 Female 97 lb 10/6/2011 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Other Serious 9/29/2010 78 Male 126 lb 10/6/2011 Physician Japan
Primary
Concomitant
Haemoptysis Life Threatening 7/1/2011 63 Male 151 lb 10/26/2011 Physician Japan
Primary
Concomitant
Anaemia Other Serious 9/30/2011 27 Male 11/17/2011 Other Health Professional Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 8/29/2011 67 Female 137 lb 11/28/2011 Physician Japan
Primary
Secondary
Concomitant
Haemoptysis Life Threatening 7/1/2011 63 Male 151 lb 12/13/2011 Physician Japan
Primary
Concomitant
Anaemia Other Serious 9/30/2011 27 Male 12/19/2011 Other Health Professional Japan
Primary
Concomitant
Opportunistic Infection Hospitalization 11/17/2011 69 Male 168 lb 12/23/2011 Physician Japan
Primary
Secondary
Concomitant
Cholangitis Acute Hospitalization 12/11/2011 62 Male 146 lb 12/28/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 11/9/2011 52 Female 116 lb 12/28/2011 Physician Japan
Primary
Concomitant
Hypoalbuminaemia Other Serious 11/15/2011 70 Male 150 lb 1/3/2012 Physician Japan
Primary
Concomitant
Cholangitis Acute Hospitalization 12/11/2011 62 Male 146 lb 1/11/2012 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 8/14/2011 67 Female 137 lb 1/23/2012 Physician Japan
Primary
Secondary
Concomitant
Cough Other Serious 2/4/2010 64 Female 108 lb 1/25/2012 Physician Japan
Primary
Concomitant
Dyspnoea Life Threatening 11/3/2011 57 Male 154 lb 1/25/2012 Physician Japan
Primary
Concomitant
Lymphopenia Hospitalization 11/17/2011 74 Female 79 lb 1/30/2012 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/15/2011 70 Male 150 lb 1/31/2012 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 12/16/2011 68 Female 123 lb 2/6/2012 Physician Japan
Primary
Concomitant
Peritoneal Tuberculosis Hospitalization 4/9/2011 79 Female 131 lb 2/8/2012 Physician Japan
Primary
Secondary
Concomitant
Tuberculous Pleurisy Hospitalization 4/9/2011 79 Female 131 lb 2/14/2012 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/14/2011 67 Female 137 lb 2/22/2012 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Other Serious 10/1/2011 68 Female 123 lb 2/23/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 2/4/2010 64 Female 108 lb 2/28/2012 Physician Japan
Primary
Concomitant
Macular Oedema Other Serious 10/19/2010 45 Female 163 lb 2/28/2012 Other Health Professional Japan
Primary
Concomitant
Cough Other Serious 2/4/2010 64 Female 108 lb 2/28/2012 Physician Japan
Primary
Concomitant
Constipation Other Serious 8/14/2011 67 Female 137 lb 3/5/2012 Physician Japan
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Other Serious 9/29/2010 78 Male 126 lb 3/6/2012 Physician Japan
Primary
Concomitant
Haemoptysis Life Threatening 7/1/2011 63 Male 151 lb 3/7/2012 Physician Japan
Primary
Concomitant
Decreased Appetite Hospitalization 1/27/2012 65 Female 4/4/2012 Japan
Primary
Concomitant
Metastases To Peritoneum Hospitalization 8/14/2011 67 Female 137 lb 4/5/2012 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Death 11/24/2010 80 Female 84 lb 4/6/2012 Physician Japan
Primary
Secondary
Concomitant
Peritoneal Tuberculosis Hospitalization 4/9/2011 79 Female 131 lb 4/9/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 5/7/2011 80 Male 4/24/2012 Physician Japan
Primary
Secondary
Concomitant
Deafness Hospitalization 1/27/2012 65 Female 4/28/2012 Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 4/20/2012 72 Male 154 lb 4/30/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 5/7/2011 80 Male 5/14/2012 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/20/2012 72 Male 154 lb 5/25/2012 Physician Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 1/27/2012 65 Female 6/8/2012 Other Health Professional Japan
Primary
Concomitant
Acute Respiratory Failure Hospitalization 11/17/2011 69 Male 168 lb 6/12/2012 Physician Japan
Primary
Secondary
Concomitant
Altered State Of Consciousness Hospitalization 11/3/2011 57 Male 154 lb 6/13/2012 Physician Japan
Primary
Concomitant
Pyrexia Death 11/2/2011 71 Female 77 lb 6/14/2012 Consumer Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Death 4/13/2012 64 Male 165 lb 6/21/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Back Pain Hospitalization 3/9/2012 88 Female 86 lb 6/26/2012 Physician Japan
Primary
Concomitant
Rectal Perforation Hospitalization 1/1/2011 74 Female 77 lb 6/26/2012 Pharmacist Japan
Primary
Concomitant
Fatigue Hospitalization 10/13/2010 78 Male 126 lb 6/27/2012 Physician Japan
Primary
Concomitant
Pyrexia Death 11/2/2011 71 Female 77 lb 6/29/2012 Consumer Japan
Primary
Concomitant
Rash Hospitalization 5/13/2012 61 Female 7/5/2012 Japan
Primary
Concomitant
Eczema Death 4/19/2012 75 Male 126 lb 7/6/2012 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/4/2011 65 Female 115 lb 7/9/2012 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 8/14/2011 67 Female 137 lb 7/10/2012 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 4/19/2012 75 Male 126 lb 7/13/2012 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 5/13/2012 7/16/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/3/2012 61 Female 7/17/2012 Physician Japan
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 4/10/2012 56 Female 112 lb 7/19/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/3/2012 61 Female 7/24/2012 Physician Japan
Primary
Secondary
Concomitant
Anaemia Hospitalization 4/10/2012 56 Female 112 lb 7/20/2012 Physician Japan
Primary
Secondary
Concomitant
Jaundice Cholestatic Other Serious 6/14/2010 68 Male 7/25/2012 Consumer Japan
Primary
Concomitant
Deafness Hospitalization 1/27/2012 65 Female 7/31/2012 Other Health Professional Japan
Primary
Concomitant
Subdural Haematoma Hospitalization 4/10/2012 56 Female 110 lb 7/31/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/3/2012 61 Female 8/2/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/3/2012 61 Female 8/15/2012 Physician Japan
Primary
Secondary
Concomitant
Sudden Hearing Loss Hospitalization 7/19/2012 8/18/2012 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 1/27/2012 8/24/2012 Japan
Primary
Secondary
Concomitant
Thrombosis Other Serious 11/24/2010 80 Female 84 lb 5/7/2013 Physician Jp
Primary
Secondary
Concomitant
Dissociative Disorder Hospitalization 6/20/2011 43 Female 117 lb 1/2/2013 Physician Jp
Primary
Secondary
Concomitant
Macular Oedema Other Serious 10/19/2010 45 Female 163 lb 11/30/2012 Other Health Professional Jp
Primary
Concomitant
Nausea Life Threatening 4/21/2009 61 Female 108 lb 2/5/2013 Physician Country Not Specified
Primary
Concomitant
Rash Hospitalization 5/13/2012 61 Female 11/19/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/4/2011 65 Female 115 lb 9/28/2012 Physician Jp
Primary
Secondary
Concomitant
Retinal Haemorrhage Hospitalization 5/13/2012 61 Female 106 lb 4/19/2013 Consumer Jp
Primary
Secondary
Concomitant
Sudden Hearing Loss Hospitalization 7/19/2012 51 Female 115 lb 8/29/2013 Physician Jp
Primary
Secondary
Concomitant
Suicide Attempt Life Threatening 8/15/2012 85 Male 121 lb 2/20/2013 Physician Jp
Primary
Concomitant
Malaise Hospitalization 1/29/2012 66 Female 11/5/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Malaise Hospitalization 1/29/2012 66 Female 139 lb 3/15/2013 Consumer Jp
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2012 51 Female 7/11/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 4/2/2012 64 Male 2/4/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2012 51 Female 104 lb 7/19/2013 Consumer Jp
Primary
Secondary
Concomitant
Hepatitis Fulminant Life Threatening 8/20/2012 75 Female 95 lb 11/21/2012 Physician Jp
Primary
Concomitant
Off Label Use 10/20/2011 44 Male 11/2/2012 Pharmacist Jp
Primary
Concomitant
Dizziness Hospitalization 1/27/2012 65 Female 11/27/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Humerus Fracture Hospitalization Female 1/16/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Pneumocystis Jirovecii Pneumonia Hospitalization 12/2/2012 82 Female 77 lb 1/28/2013 Physician Jp
Primary
Secondary
Concomitant
Haemorrhage Subcutaneous Other Serious 1/11/2013 Female 172 lb 3/21/2013 Physician Jp
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/11/2012 74 Female 10/21/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 11/21/2012 65 Female 5/29/2013 Pharmacist Jp
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization Male 3/28/2013 Consumer Jp
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 3/21/2013 56 Male 159 lb 6/17/2013 Physician Jp
Primary
Concomitant
Renal Failure Acute Hospitalization 4/11/2013 57 Female 148 lb 6/4/2013 Physician Jp
Primary
Concomitant
Gastrointestinal Perforation Hospitalization 4/11/2013 62 Male 123 lb 10/23/2013 Pharmacist Jp
Primary
Secondary
Concomitant
Drug Effect Incomplete 4/22/2013 63 Male 170 lb 9/24/2013 Consumer Jp
Primary
Concomitant
Blood Pressure Decreased Life Threatening 5/2013 Female 6/17/2013 Pharmacist Jp
Primary
Concomitant
Loss Of Consciousness Other Serious 5/18/2012 66 Female 123 lb 7/9/2013 Consumer Jp
Primary
Secondary
Concomitant
Stomatitis Death 6/28/2013 40 Male 168 lb 9/23/2013 Physician Jp
Primary
Concomitant
Perivascular Dermatitis Other Serious 4/22/2013 44 Male 117 lb 8/14/2013 Physician Jp
Primary
Concomitant
Renal Function Test Abnormal Other Serious 6/27/2013 60 Female 103 lb 9/18/2013 Pharmacist Jp
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 6/7/2013 55 Male 8/17/2013 Consumer Us
Primary
Secondary
Concomitant

Drug Data