Loxonin combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ureteral Catheterisation Life Threatening 5/29/2006 57 Male 121 lb 7/13/2006 Physician Japan
Primary
Concomitant
Vagus Nerve Disorder Hospitalization 6/1/2006 64 Male 170 lb 7/21/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/29/2006 77 Female 9/28/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/1/2006 70 Female 110 lb 10/20/2006 Physician Japan
Primary
Secondary
Concomitant
Toothache Other Serious 10/5/2006 66 Male 10/23/2006 Physician Japan
Primary
Concomitant
Toothache Other Serious 10/5/2006 66 Male 10/23/2006 Physician Japan
Primary
Concomitant
Myalgia Hospitalization 10/4/2006 58 Male 10/30/2006 Physician Japan
Primary
Concomitant
Pain In Jaw Other Serious Male 11/10/2006 Physician Japan
Primary
Concomitant
Ureteral Catheterisation Life Threatening 5/29/2006 57 Male 121 lb 11/17/2006 Physician Japan
Primary
Concomitant
Toothache 10/5/2006 66 Male 12/8/2006 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 11/1/2006 Male 12/14/2006 Pharmacist Japan
Primary
Concomitant
Toothache Other Serious 10/21/2006 70 Male 331 lb 12/16/2006 Physician Japan
Primary
Concomitant
Vomiting Other Serious 11/3/2006 69 Male 366 lb 12/19/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Uterine Neoplasm Hospitalization 12/1/2006 72 Female 115 lb 2/15/2007 Physician Japan
Primary
Concomitant
Optic Neuritis Retrobulbar Other Serious 8/22/2006 65 Female 6/23/2007 Physician Japan
Primary
Concomitant
Myalgia Hospitalization 10/4/2006 58 Male 6/23/2007 Physician Japan
Primary
Concomitant
Shock Death 4/18/2007 71 Female 102 lb 7/9/2007 Physician Japan
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 6/13/2007 66 Male 108 lb 8/1/2007 Physician Japan
Primary
Secondary
Concomitant
Poor Personal Hygiene Other Serious 5/8/2007 58 Female 8/8/2007 Physician Japan
Primary
Secondary
Concomitant
Paralysis Other Serious 6/22/2006 80 Male 9/5/2007 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/22/2006 80 Male 9/12/2007 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/22/2006 80 Male 10/12/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Death 7/10/2007 52 Female 10/29/2007 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/19/2007 66 Female 11/17/2007 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/1/2006 66 Female 86 lb 12/10/2007 Physician Japan
Primary
Secondary
Concomitant
Tetany Hospitalization 11/1/2007 60 Male 119 lb 12/14/2007 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 12/1/2006 66 Female 86 lb 12/20/2007 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Other Serious 1/18/2008 47 Female 106 lb 2/11/2008 Physician Japan
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 10/14/2007 85 Male 146 lb 2/28/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/15/2008 76 Male 110 lb 3/4/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/18/2008 47 Female 106 lb 3/10/2008 Physician Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 4/1/2007 73 Male 148 lb 3/11/2008 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/15/2008 76 Male 110 lb 4/4/2008 Physician Japan
Primary
Secondary
Concomitant
Toothache Other Serious 7/11/2007 121 lb 4/8/2008 Physician Japan
Primary
Concomitant
Toothache Other Serious 7/11/2007 74 Male 121 lb 4/11/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/15/2008 76 Male 110 lb 5/10/2008 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 4/19/2008 6/12/2008 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 6/3/2008 77 Male 146 lb 6/20/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/13/2008 74 Female 6/24/2008 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 4/29/2008 70 Male 6/25/2008 Japan
Primary
Concomitant
Neutropenia Hospitalization 6/13/2008 74 Female 7/7/2008 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 4/29/2008 70 Male 7/14/2008 Japan
Primary
Concomitant
Rash Other Serious 4/29/2008 70 Male 8/11/2008 Japan
Primary
Concomitant
Pain In Jaw Other Serious 6/1/2008 Female 8/14/2008 Physician
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 5/2/2008 9/9/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/2/2008 10/3/2008 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 5/26/2008 Female 77 lb 10/8/2008 Physician Japan
Primary
Concomitant
Urine Output Decreased Other Serious 8/14/2008 Male 104 lb 10/14/2008 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 4/1/2007 Male 148 lb 11/3/2008 Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 10/1/2004 Female 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 6/1/2008 Female 11/11/2008 Physician Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 4/1/2007 Male 148 lb 11/13/2008 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/12/2008 Male 104 lb 11/17/2008 Pharmacist Japan
Primary
Concomitant
Pain In Jaw Other Serious 6/1/2008 Female 115 lb 11/19/2008 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 4/1/2008 Female 11/20/2008 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 6/13/2007 Female 77 lb 12/3/2008 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 6/13/2007 Female 77 lb 1/2/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/2/2008 Female 106 lb 1/7/2009 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 12/1/2007 Female 139 lb 2/13/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 1/7/2009 74 Male 2/27/2009 Physician Japan
Primary
Secondary
Concomitant
Prostate Cancer Death 10/9/2007 72 Male 2/27/2009 Japan
Primary
Concomitant
Prostate Cancer Death 10/9/2007 72 Male 3/2/2009 Japan
Primary
Concomitant
Osteonecrosis Other Serious 4/1/2008 Female 3/6/2009 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 12/1/2007 Female 139 lb 3/9/2009 Physician Japan
Primary
Secondary
Concomitant
Prostate Cancer Death 10/9/2007 72 Male 3/12/2009 Japan
Primary
Concomitant
Hypercalcaemia Life Threatening 2/18/2009 Female 84 lb 3/13/2009 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Death 1/24/2009 80 Female 117 lb 3/17/2009 Other Health Professional Japan
Primary
Concomitant
Malignant Neoplasm Progression Death 4/7/2008 Male 3/25/2009 Physician Japan
Primary
Concomitant
Concomitant Disease Aggravated Other Serious 2/18/2009 Female 84 lb 3/26/2009 Physician Japan
Primary
Concomitant
Prostate Cancer Death 10/9/2007 72 Male 4/3/2009 Japan
Primary
Concomitant
Pulmonary Hypertension Life Threatening 1/7/2009 Male 4/9/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Life Threatening 1/7/2009 Male 4/9/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Life Threatening 1/7/2009 Male 4/13/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Haemorrhage Other Serious 5/7/2008 70 Male 4/14/2009 Physician Japan
Primary
Concomitant
Osteomyelitis Other Serious 9/7/2008 71 Male 4/15/2009 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 4/1/2008 Female 4/21/2009 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Death 2/21/2008 Male 4/22/2009 Physician Japan
Primary
Concomitant
Death Death 4/13/2009 60 5/21/2009 Physician Japan
Primary
Concomitant
Renal Haemorrhage Other Serious 5/7/2008 70 Male 5/26/2009 Physician Japan
Primary
Concomitant
Prostate Cancer Recurrent Other Serious 9/7/2008 Male 6/5/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/1/2009 Male 6/16/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 2/1/2009 Female 6/22/2009 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Death 4/13/2009 60 6/24/2009 Physician Japan
Primary
Concomitant
Sequestrectomy Hospitalization 2/1/2009 Male 150 lb 6/26/2009 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 10/1/2008 Male 7/7/2009 Other Health Professional Japan
Primary
Concomitant
Toothache Other Serious 10/8/2008 Male 7/13/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/6/2009 Female 99 lb 7/13/2009 Physician Japan
Primary
Secondary
Concomitant
Toothache Hospitalization 2/1/2009 Female 8/11/2009 Physician Japan
Primary
Concomitant
Toothache Hospitalization 2/1/2009 Female 8/13/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/1/2009 Male 9/3/2009 Pharmacist Japan
Primary
Concomitant
Purulent Discharge Hospitalization 12/1/2008 Female 9/7/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/6/2009 Female 99 lb 9/8/2009 Physician Japan
Primary
Secondary
Concomitant
Purulent Discharge Hospitalization 12/1/2008 Female 9/17/2009 Physician Japan
Primary
Concomitant
Toothache Other Serious 3/12/2008 Male 110 lb 10/10/2009 Physician Japan
Primary
Secondary
Concomitant
Swelling Other Serious 7/21/2009 Male 104 lb 10/12/2009 Physician Japan
Primary
Concomitant
Swelling Other Serious 4/30/2009 Male 104 lb 10/14/2009 Physician Japan
Primary
Concomitant
Swelling Other Serious 4/30/2009 Male 104 lb 10/20/2009 Other Health Professional Japan
Primary
Concomitant
Toothache Other Serious 3/12/2008 Male 110 lb 10/29/2009 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 10/1/2008 Male 11/2/2009 Other Health Professional Japan
Primary
Concomitant
Prostate Cancer Death 5/31/2009 46 Male 11/13/2009 Japan
Primary
Concomitant
Prostate Cancer Death 5/31/2009 46 Male 11/25/2009 Japan
Primary
Concomitant
Rash Death 1/1/2005 80 Female 117 lb 12/14/2009 Physician Japan
Primary
Concomitant
Toothache Other Serious 3/1/2009 Female 101 lb 12/21/2009 Pharmacist Japan
Primary
Concomitant
Yellow Skin Other Serious 8/6/2008 56 Female 99 lb 2/9/2010 Physician Japan
Primary
Concomitant
Toothache Other Serious 11/14/2007 71 Female 2/17/2010 Physician Japan
Primary
Concomitant
Swelling Hospitalization 2/17/2010 Female 106 lb 2/24/2010 Physician Japan
Primary
Secondary
Concomitant
Swelling Hospitalization 10/3/2009 Female 152 lb 2/24/2010 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 12/29/2009 Female 106 lb 3/5/2010 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 1/27/2010 56 Female 106 lb 3/10/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Toothache Other Serious 11/14/2007 Female 97 lb 3/11/2010 Physician Japan
Primary
Concomitant
Swelling Hospitalization 10/1/2009 Female 152 lb 3/12/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 1/27/2010 56 Female 3/18/2010 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 8/14/2009 56 Female 106 lb 3/22/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 1/27/2010 56 Female 3/25/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Haemorrhage Other Serious 5/7/2008 70 Male 4/16/2010 Physician Japan
Primary
Concomitant
Swelling Hospitalization 10/1/2009 62 Female 152 lb 4/27/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/25/2009 66 Male 119 lb 4/29/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/25/2009 66 Male 119 lb 6/1/2010 Physician Japan
Primary
Concomitant
Tooth Extraction Hospitalization 12/29/2009 63 Female 106 lb 6/3/2010 Physician Japan
Primary
Secondary
Concomitant
Prostate Cancer Death 5/31/2009 46 Male 150 lb 6/29/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 4/5/2010 68 Male 132 lb 7/1/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 4/5/2010 68 Male 132 lb 8/3/2010 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 9/15/2009 52 Male 117 lb 8/5/2010 Physician Japan
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/15/2009 52 Male 117 lb 9/24/2010 Physician Japan
Primary
Concomitant
Hyperglycaemia Hospitalization 7/29/2010 52 Male 10/21/2010 Physician Japan
Primary
Concomitant
Osteonecrosis Of Jaw Hospitalization 5/26/2008 76 Male 77 lb 10/26/2010 Pharmacist Japan
Primary
Concomitant
Prostate Cancer Death 4/8/2010 83 Male 10/28/2010 Other Health Professional Japan
Primary
Concomitant
Prostate Cancer Death 4/8/2010 83 Male 11/9/2010 Other Health Professional Japan
Primary
Concomitant
Stomatitis Other Serious 12/30/2009 74 Female 112 lb 11/10/2010 Physician Japan
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious Female 11/15/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 10/20/2010 11/17/2010 Other Health Professional Japan
Primary
Concomitant
Radiation Pneumonitis Other Serious 8/6/2010 62 Male 11/17/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 10/20/2010 11/30/2010 Physician Japan
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 8/6/2010 59 Female 12/7/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 9/21/2010 12/9/2010 Other Health Professional Japan
Primary
Concomitant
Radiation Pneumonitis Other Serious 8/6/2010 62 Male 12/13/2010 Physician Japan
Primary
Concomitant
Wound Complication 1/21/2010 59 Female 115 lb 12/14/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Ovarian Cancer Other Serious 12/30/2009 74 Female 112 lb 12/15/2010 Physician Japan
Primary
Concomitant
Periodontitis 1/21/2010 59 Female 115 lb 12/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 10/20/2010 12/20/2010 Japan
Primary
Concomitant
Blood Urea Increased Hospitalization 6/16/2007 73 Male 148 lb 1/10/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Decreased Appetite Death 10/18/2008 46 Female 112 lb 1/17/2011 Physician Japan
Primary
Concomitant
Blood Urea Increased Hospitalization 2/1/2009 79 Male 1/18/2011 Pharmacist Japan
Primary
Concomitant
Blood Creatinine Increased Hospitalization 2/1/2009 79 Male 1/21/2011 Pharmacist Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/16/2007 73 Male 148 lb 1/25/2011 Japan
Primary
Secondary
Concomitant
Sensory Disturbance Other Serious 10/18/2008 46 Female 112 lb 1/26/2011 Physician Japan
Primary
Concomitant
Anaemia Other Serious 10/18/2008 46 Female 112 lb 1/27/2011 Physician Japan
Primary
Concomitant
Convulsion Hospitalization 12/15/2010 57 Male 1/27/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 10/25/2010 61 Male 143 lb 1/28/2011 Physician Japan
Primary
Concomitant
Rectal Cancer Death 12/15/2010 57 Male 2/1/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data