Loxonin combined with Vx-950 (Telaprevir)

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neutrophil Count Decreased Other Serious 1/17/2012 56 Female 12/27/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 1/17/2012 56 Female 8/5/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Drug Eruption Hospitalization 2/19/2012 57 Male 2/26/2013 Other Health Professional Jp
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 2/27/2012 67 Male 5/20/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 2/14/2012 49 Male 3/20/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Psychiatric Symptom Other Serious 2/9/2012 64 Female 7/29/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Blood Uric Acid Increased Other Serious 2/7/2012 57 Male 12/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/13/2012 54 Female 2/27/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Disorder Other Serious 2/22/2012 66 Male 1/28/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/16/2012 54 Female 11/20/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/10/2012 64 Male 12/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Mania Other Serious 4/1/2012 60 Female 5/28/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Delirium Other Serious 3/14/2012 55 Male 9/20/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Drug Eruption Other Serious 2/28/2012 71 Male 12/31/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Vomiting Other Serious 4/9/2012 67 Male 2/4/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Other Serious 3/17/2012 48 Male 12/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/11/2012 60 Male 12/27/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 5/25/2012 60 Female 3/14/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 4/11/2012 70 Female 9/20/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/2/2012 50 Male 12/20/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Presyncope Hospitalization 5/1/2012 63 Male 1/28/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 3/13/2012 68 Male 7/23/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Other Serious 5/17/2012 63 Male 9/3/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 5/8/2012 65 Female 9/20/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Other Serious 5/11/2012 62 Male 12/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Other Serious 5/11/2012 62 Male 7/15/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/1/2012 59 Female 9/10/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/3/2012 61 Female 4/19/2013 Other Health Professional Jp
Primary
Concomitant
Erythema Hospitalization 2/10/2012 54 Male 2/7/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Seborrhoeic Dermatitis Hospitalization 4/20/2012 67 Male 4/29/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 6/5/2012 58 Male 3/20/2013 Other Health Professional Jp
Primary
Concomitant
Syncope Other Serious 5/30/2012 47 Male 4/12/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Other Serious 6/25/2012 65 Female 3/12/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 8/7/2012 65 Female 4/5/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Heat Illness Death 8/17/2012 67 Female 5/14/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 8/8/2012 49 Female 3/29/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 8/15/2012 45 Male 12/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 8/15/2012 45 Male 8/15/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Other Serious 8/2/2012 61 Male 4/11/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Drug Eruption Other Serious 5/10/2012 55 Male 9/17/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 5/24/2012 48 Male 4/8/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/3/2012 65 Male 9/4/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Nausea Hospitalization 7/13/2012 60 Female 5/1/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/22/2012 62 Male 8/16/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/14/2012 66 Female 2/5/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 7/3/2012 55 Female 9/18/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinal Haemorrhage Other Serious 5/2/2012 45 Male 6/20/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinopathy Other Serious 5/28/2012 62 Male 5/22/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Malaise 5/28/2012 49 Male 5/1/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinopathy Other Serious 8/15/2012 50 Male 4/17/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Sepsis Other Serious 7/4/2012 68 Female 9/10/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 8/11/2012 57 Female 9/24/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Psychiatric Symptom Hospitalization 6/1/2012 61 Male 9/24/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Gastritis Haemorrhagic Other Serious 2/3/2012 66 Female 2/25/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Other Serious 6/6/2012 52 Male 8/23/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Bronchitis Hospitalization 4/20/2012 69 Female 4/25/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 2/20/2012 55 Male 7/30/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Depression Other Serious 3/21/2012 69 Male 9/10/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Other Serious 6/6/2012 59 Female 9/17/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinal Haemorrhage Other Serious 9/4/2012 66 Male 3/21/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Off Label Use Other Serious 7/23/2012 53 Male 5/31/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Malaise Hospitalization 5/8/2012 47 Male 11/8/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinopathy Other Serious 7/17/2012 71 Female 3/4/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 3/23/2012 38 Male 1/15/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 7/31/2012 40 Female 5/16/2013 Other Health Professional Jp
Primary
Concomitant
Erythema Hospitalization 4/27/2012 56 Male 1/2/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 5/2/2012 67 Female 9/10/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment 6/26/2012 65 Male 4/11/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Erythema Other Serious 3/17/2012 66 Male 5/24/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Other Serious 6/15/2012 63 Male 3/11/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinopathy Other Serious 7/26/2012 57 Male 9/11/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 7/3/2012 37 Female 3/11/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/28/2012 60 Male 1/11/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Off Label Use Hospitalization 3/29/2012 64 Male 11/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 4/12/2012 69 Male 11/20/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Psychiatric Symptom Hospitalization 4/11/2012 70 Female 1/25/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 9/8/2012 63 Male 12/14/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 9/8/2012 63 Male 8/6/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Pancytopenia Other Serious 3/2/2012 64 Male 5/15/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 8/29/2012 52 Female 4/29/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Nausea Other Serious 3/17/2012 44 Female 7/8/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/24/2012 52 Female 8/2/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 3/24/2012 64 Female 6/10/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/2/2012 61 Male 1/28/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinal Haemorrhage Other Serious 9/21/2012 75 Female 5/2/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 6/27/2012 66 Female 1/31/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Spinal Column Stenosis Other Serious 8/2/2012 60 Female 9/10/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/17/2012 58 Male 5/15/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 8/31/2012 32 Female 7/30/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Drug Eruption Other Serious 8/7/2012 50 Female 7/29/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Drug Eruption Other Serious 10/4/2012 70 Male 11/15/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinal Haemorrhage Other Serious 8/14/2012 64 Male 12/19/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Erythema Other Serious 8/3/2012 55 Female 6/26/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 4/12/2012 48 Male 3/25/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 9/6/2012 51 Male 12/3/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 9/6/2012 51 Male 7/19/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Depression Hospitalization 9/10/2012 63 Female 12/26/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 8/16/2012 73 Male 11/16/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Exposure During Pregnancy Hospitalization 9/2/2012 76 Female 3/11/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Somnolence Other Serious 6/14/2012 61 Male 4/17/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 8/1/2012 59 Male 5/1/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Depression Other Serious 8/28/2012 45 Male 8/9/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 4/11/2012 63 Female 9/20/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 9/14/2012 47 Male 9/18/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/11/2012 64 Male 6/6/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 5/14/2012 56 Female 6/12/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 5/9/2012 80 Female 2/5/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Sepsis Death 8/21/2012 51 Male 9/17/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/11/2012 48 Female 11/9/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 7/17/2012 68 Female 11/12/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment 7/25/2012 51 Male 1/30/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/24/2012 59 Female 11/14/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/23/2012 53 Female 11/14/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Hospitalization 4/11/2012 53 Male 2/14/2013 Other Health Professional Jp
Primary
Concomitant
Retinal Haemorrhage Other Serious 2/9/2012 50 Male 4/25/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 3/6/2012 59 Female 11/19/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Insomnia Hospitalization 2/11/2012 59 Female 11/19/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/26/2012 62 Female 11/27/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 10/30/2012 50 Male 6/11/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Malaise Hospitalization 1/24/2012 63 Female 11/20/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Malaise Hospitalization 4/20/2012 51 Male 11/20/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Malaise Hospitalization 4/20/2012 51 Male 9/11/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Other Serious 8/17/2012 63 Female 8/1/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Cough 7/12/2012 47 Female 2/12/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/20/2012 53 Female 9/18/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 6/6/2012 57 Female 11/21/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 5/14/2012 65 Male 11/27/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 9/19/2012 62 Male 12/21/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2012 53 Male 11/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2012 53 Male 9/10/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Nausea Hospitalization 4/20/2012 64 Male 11/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 2/2/2012 59 Female 11/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 2/21/2012 64 Male 11/29/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 11/16/2012 73 Female 12/13/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Blood Potassium Increased Other Serious 11/5/2012 51 Male 6/11/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/4/2012 60 Male 9/20/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Other Serious 8/18/2012 45 Male 9/10/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/3/2012 66 Male 12/18/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinopathy Other Serious 9/28/2012 64 Male 12/19/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinopathy Other Serious 9/28/2012 64 Male 9/4/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Completed Suicide Death 12/14/2012 46 Male 4/3/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/19/2012 64 Male 12/27/2012 Other Health Professional Jp
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/19/2012 64 Male 7/2/2013 Other Health Professional Jp
Primary
Concomitant
Neutrophil Count Decreased Other Serious 7/12/2012 67 Male 12/31/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 7/12/2012 67 Male 7/31/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Pancytopenia Other Serious 3/12/2012 53 Male 1/22/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/6/2012 47 Male 2/1/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinal Haemorrhage Other Serious 3/27/2012 63 Male 3/14/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Depression Other Serious 6/12/2012 49 Female 3/26/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 5/25/2012 70 Male 4/29/2013 Other Health Professional Jp
Primary
Secondary
Concomitant

Drug Data