Loxonin combined with Telavic (Telaprevir)

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Diarrhoea Hospitalization 12/28/2011 40 Male 3/1/2012 Other Health Professional Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 2/19/2012 57 Male 3/7/2012 Japan
Primary
Concomitant
Erythema Other Serious 2/27/2012 58 Male 3/9/2012 Other Health Professional Japan
Primary
Concomitant
Decreased Appetite Hospitalization 2/3/2012 64 Male 3/14/2012 Other Health Professional Japan
Primary
Concomitant
Drug Eruption Hospitalization 2/24/2012 67 Male 3/15/2012 Japan
Primary
Concomitant
Decreased Appetite Other Serious 2/19/2012 57 Male 3/16/2012 Other Health Professional Japan
Primary
Concomitant
Asthenia Hospitalization 3/2/2012 49 Female 3/16/2012 Japan
Primary
Concomitant
Depressive Symptom Hospitalization 2/3/2012 66 Female 3/21/2012 Other Health Professional Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 2/14/2012 49 Male 3/26/2012 Other Health Professional Japan
Primary
Concomitant
Sudden Hearing Loss Hospitalization 3/17/2012 68 Female 3/26/2012 Japan
Primary
Concomitant
Psychiatric Symptom Other Serious 2/6/2012 64 Female 3/30/2012 Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 1/20/2012 53 Female 4/2/2012 Japan
Primary
Concomitant
Renal Failure Acute Other Serious 3/15/2012 59 Male 4/3/2012 Other Health Professional Japan
Primary
Concomitant
Gastrointestinal Disorder Other Serious 3/7/2012 42 Male 4/4/2012 Japan
Primary
Concomitant
Nausea Other Serious 2/16/2012 62 Female 4/6/2012 Japan
Primary
Concomitant
Blood Creatinine Increased Hospitalization 2/23/2012 50 Female 4/9/2012 Other Health Professional Japan
Primary
Concomitant
Blood Uric Acid Increased Other Serious 2/7/2012 57 Male 4/9/2012 Japan
Primary
Concomitant
Pancytopenia Other Serious 1/24/2012 59 Female 4/11/2012 Japan
Primary
Concomitant
Rash Other Serious 4/4/2012 62 Male 4/12/2012 Japan
Primary
Concomitant
Decreased Appetite Other Serious 2/19/2012 57 Male 4/18/2012 Japan
Primary
Concomitant
Rash Other Serious 4/4/2012 62 Male 4/18/2012 Other Health Professional Japan
Primary
Concomitant
Pyrexia Other Serious 2/27/2012 58 Male 4/19/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2012 53 Male 4/20/2012 Japan
Primary
Concomitant
Sudden Hearing Loss Hospitalization 2/17/2012 68 Female 4/20/2012 Japan
Primary
Concomitant
Depression Hospitalization 2/27/2012 54 Female 4/20/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Other Serious 2/22/2012 66 Male 4/20/2012 Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/20/2012 36 Female 4/20/2012 Japan
Primary
Concomitant
Insomnia Hospitalization 2/10/2012 59 Female 4/23/2012 Other Health Professional Japan
Primary
Concomitant
Malaise Other Serious 1/24/2012 63 Female 4/24/2012 Japan
Primary
Concomitant
Pancytopenia Other Serious 1/24/2012 59 Female 4/24/2012 Japan
Primary
Concomitant
Rash Other Serious 4/4/2012 62 Male 4/25/2012 Japan
Primary
Concomitant
Nausea Other Serious 2/16/2012 54 Female 4/26/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2012 53 Male 4/26/2012 Japan
Primary
Concomitant
Decreased Appetite Hospitalization 2/2/2012 59 Female 4/30/2012 Other Health Professional Japan
Primary
Concomitant
Rash Other Serious 3/29/2012 62 Male 4/30/2012 Japan
Primary
Concomitant
Rash Other Serious 1/22/2012 59 Male 5/2/2012 Other Health Professional Japan
Primary
Concomitant
Somnolence Hospitalization 2/24/2012 59 Female 5/2/2012 Japan
Primary
Concomitant
Asthenia Hospitalization 3/2/2012 49 Female 5/3/2012 Japan
Primary
Concomitant
Erythema Multiforme Other Serious 2/21/2012 64 Male 5/3/2012 Japan
Primary
Concomitant
Anaemia Hospitalization 1/1/2012 63 Female 5/4/2012 Japan
Primary
Concomitant
Decreased Appetite Other Serious 3/6/2012 59 Female 5/4/2012 Japan
Primary
Concomitant
Malaise Other Serious 1/1/2012 63 Female 5/4/2012 Other Health Professional Japan
Primary
Concomitant
Decreased Appetite Other Serious 2/24/2012 67 Male 5/6/2012 Japan
Primary
Concomitant
Mania Other Serious 4/1/2012 60 Female 5/7/2012 Japan
Primary
Concomitant
Renal Impairment Other Serious 3/26/2012 61 Male 5/7/2012 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 2/4/2012 60 Male 5/7/2012 Japan
Primary
Concomitant
Drug Eruption Other Serious 4/26/2012 71 Male 5/8/2012 Japan
Primary
Concomitant
Neutropenia Other Serious 2/23/2012 54 Male 5/8/2012 Other Health Professional Japan
Primary
Concomitant
Renal Impairment 3/26/2012 61 Male 5/8/2012 Japan
Primary
Concomitant
Neutropenia Hospitalization 2/23/2012 54 Male 5/9/2012 Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 3/23/2012 38 Male 5/10/2012 Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 2/14/2012 49 Male 5/10/2012 Other Health Professional Japan
Primary
Concomitant
Depressive Symptom Other Serious 2/3/2012 66 Female 5/14/2012 Japan
Primary
Concomitant
Erythema Multiforme Other Serious 2/6/2012 56 Male 5/14/2012 Japan
Primary
Concomitant
Malaise Hospitalization 3/29/2012 64 Male 5/14/2012 Japan
Primary
Concomitant
Erythema Multiforme Other Serious 3/7/2012 42 Male 5/16/2012 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 4/11/2012 63 Female 5/16/2012 Japan
Primary
Concomitant
Drug Eruption Other Serious 2/28/2012 71 Male 5/16/2012 Other Health Professional Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 2/4/2012 60 Male 5/17/2012 Japan
Primary
Concomitant
Pancytopenia Other Serious 2/9/2012 50 Male 5/17/2012 Japan
Primary
Concomitant
Generalised Erythema Hospitalization 4/25/2012 45 Male 5/18/2012 Japan
Primary
Concomitant
Skin Exfoliation Other Serious 5/2/2012 62 Female 5/18/2012 Japan
Primary
Concomitant
Pancytopenia Other Serious 1/24/2012 59 Female 5/23/2012 Japan
Primary
Concomitant
Pancytopenia Other Serious 2/9/2012 50 Male 5/23/2012 Other Health Professional Japan
Primary
Concomitant
Orthostatic Hypotension Hospitalization 1/20/2012 36 Female 5/24/2012 Other Health Professional Japan
Primary
Concomitant
Blood Creatinine Increased Hospitalization 2/23/2012 50 Female 5/24/2012 Other Health Professional Japan
Primary
Concomitant
Blood Uric Acid Increased Hospitalization 5/8/2012 47 Male 5/25/2012 Other Health Professional Japan
Primary
Concomitant
Hyperuricaemia Hospitalization 2/22/2012 66 Male 5/25/2012 Other Health Professional Japan
Primary
Concomitant
Rash Other Serious 3/17/2012 48 Male 5/25/2012 Other Health Professional Japan
Primary
Concomitant
Depression Hospitalization 2/27/2012 54 Female 5/29/2012 Other Health Professional Japan
Primary
Concomitant
Renal Disorder Other Serious 2/22/2012 66 Male 5/30/2012 Japan
Primary
Concomitant
Arrhythmia Life Threatening 5/19/2012 Male 6/1/2012 Other Health Professional Japan
Primary
Concomitant
Impulsive Behaviour Hospitalization 2/6/2012 64 Female 6/1/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Other Serious 3/9/2012 46 Female 6/1/2012 Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 4/17/2012 39 Male 6/1/2012 Japan
Primary
Concomitant
Toxic Skin Eruption Other Serious 3/5/2012 68 Female 6/3/2012 Japan
Primary
Concomitant
Hypoalbuminaemia Other Serious 2/24/2012 59 Female 6/6/2012 Japan
Primary
Concomitant
Loss Of Consciousness Other Serious 2/16/2012 62 Female 6/6/2012 Other Health Professional Japan
Primary
Concomitant
Erythema Multiforme Other Serious 2/6/2012 56 Male 6/6/2012 Japan
Primary
Concomitant
Rash Hospitalization 4/11/2012 53 Male 6/6/2012 Japan
Primary
Concomitant
Renal Tubular Necrosis Other Serious 3/15/2012 59 Male 6/6/2012 Japan
Primary
Concomitant
Nausea Other Serious 2/16/2012 54 Female 6/6/2012 Japan
Primary
Concomitant
Erythema Multiforme Other Serious 2/21/2012 64 Male 6/6/2012 Japan
Primary
Concomitant
Anaemia Hospitalization 1/1/2012 63 Female 6/6/2012 Other Health Professional Japan
Primary
Concomitant
Asthenia Other Serious 2/19/2012 57 Male 6/8/2012 Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 3/2/2012 64 Male 6/8/2012 Other Health Professional Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 4/11/2012 70 Female 6/8/2012 Other Health Professional Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 2/2/2012 50 Male 6/11/2012 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/11/2012 60 Male 6/11/2012 Japan
Primary
Concomitant
Pancytopenia Other Serious 3/2/2012 64 Male 6/11/2012 Japan
Primary
Concomitant
Anaemia Other Serious 1/1/2012 63 Female 6/13/2012 Other Health Professional Japan
Primary
Concomitant
Pancytopenia Other Serious 1/24/2012 59 Female 6/14/2012 Japan
Primary
Concomitant
Drug Eruption Other Serious 3/29/2012 62 Male 6/14/2012 Other Health Professional Japan
Primary
Concomitant
Erythema Hospitalization 2/2/2012 50 Male 6/14/2012 Other Health Professional Japan
Primary
Concomitant
Pancytopenia Other Serious 3/2/2012 64 Male 6/15/2012 Other Health Professional Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 4/9/2012 67 Male 6/16/2012 Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 5/15/2012 Male 6/18/2012 Other Health Professional Japan
Primary
Concomitant
Cardiac Failure Life Threatening 5/15/2012 Male 6/18/2012 Other Health Professional Japan
Primary
Concomitant
Erythema Multiforme Other Serious 3/7/2012 42 Male 6/20/2012 Japan
Primary
Concomitant
Vomiting Hospitalization 5/25/2012 60 Female 6/20/2012 Other Health Professional Japan
Primary
Concomitant
Small Intestine Ulcer Hospitalization 4/11/2012 60 Male 6/20/2012 Other Health Professional Japan
Primary
Concomitant
Bronchitis Hospitalization 4/20/2012 69 Female 6/21/2012 Other Health Professional Japan
Primary
Concomitant
Pneumonia Hospitalization 5/2/2012 68 Male 6/25/2012 Other Health Professional Japan
Primary
Concomitant
Decreased Appetite Hospitalization 2/2/2012 59 Female 6/26/2012 Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Other Serious 1/20/2012 53 Female 6/26/2012 Japan
Primary
Concomitant
Anaemia Hospitalization 1/1/2012 63 Female 6/26/2012 Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 1/20/2012 53 Female 6/29/2012 Japan
Primary
Concomitant
Erythema Multiforme Hospitalization 5/2/2012 67 Female 6/29/2012 Japan
Primary
Concomitant
Rash Other Serious 1/22/2012 59 Male 6/29/2012 Other Health Professional Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/20/2012 36 Female 6/29/2012 Other Health Professional Japan
Primary
Concomitant
Haemoglobin Decreased Hospitalization 6/14/2012 62 Female 7/2/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/5/2012 68 Female 7/2/2012 Japan
Primary
Concomitant
Herpes Zoster Other Serious 5/8/2012 65 Female 7/2/2012 Other Health Professional Japan
Primary
Concomitant
Erythema Multiforme Other Serious 4/20/2012 50 Male 7/3/2012 Other Health Professional Japan
Primary
Concomitant
Malaise Hospitalization 3/29/2012 64 Male 7/3/2012 Japan
Primary
Concomitant
Off Label Use Other Serious 5/11/2012 62 Male 7/5/2012 Japan
Primary
Concomitant
Diabetes Mellitus Hospitalization 5/23/2012 48 Male 7/5/2012 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 5/9/2012 80 Female 7/5/2012 Japan
Primary
Concomitant
Renal Impairment Other Serious 4/23/2012 64 Male 7/6/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/14/2012 62 Female 7/6/2012 Other Health Professional Japan
Primary
Concomitant
Somnolence Hospitalization 6/14/2012 61 Male 7/10/2012 Japan
Primary
Concomitant
Erythema Hospitalization 4/27/2012 56 Male 7/10/2012 Japan
Primary
Concomitant
Decreased Appetite Other Serious 3/6/2012 59 Female 7/10/2012 Japan
Primary
Concomitant
Off Label Use Other Serious 5/1/2012 59 Female 7/11/2012 Other Health Professional Japan
Primary
Concomitant
Vomiting Hospitalization 6/3/2012 61 Female 7/11/2012 Japan
Primary
Concomitant
Renal Disorder 5/28/2012 70 Female 7/13/2012 Other Health Professional Japan
Primary
Concomitant
Depression Other Serious 2/22/2012 66 Male 7/17/2012 Other Health Professional Japan
Primary
Concomitant
Stomatitis Hospitalization 12/28/2011 40 Male 7/17/2012 Japan
Primary
Concomitant
Anaemia Other Serious 5/1/2012 72 Male 7/19/2012 Other Health Professional Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/17/2012 56 Female 7/20/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/24/2012 59 Female 7/20/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Hospitalization 1/13/2012 54 Female 7/20/2012 Japan
Primary
Concomitant
Anaemia Hospitalization 1/1/2012 63 Female 7/20/2012 Other Health Professional Japan
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 5/17/2012 63 Male 7/20/2012 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 6/18/2012 61 Female 7/23/2012 Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 5/29/2012 51 Male 7/23/2012 Japan
Primary
Concomitant
Anaemia Other Serious 1/13/2012 54 Female 7/23/2012 Japan
Primary
Concomitant
Rash Other Serious 54 Male 7/23/2012 Japan
Primary
Concomitant
Pyelonephritis Hospitalization 5/25/2012 70 Male 7/23/2012 Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 2/4/2012 60 Male 7/24/2012 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/20/2012 36 Female 7/24/2012 Japan
Primary
Concomitant
Decreased Appetite Hospitalization 7/13/2012 70 Female 7/25/2012 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2012 53 Male 7/26/2012 Japan
Primary
Concomitant
Erythema Hospitalization 4/27/2012 56 Male 7/27/2012 Japan
Primary
Concomitant
Anaemia Other Serious 3/2/2012 49 Female 7/30/2012 Japan
Primary
Concomitant
Blood Creatinine Increased Other Serious 7/4/2012 66 Male 7/30/2012 Japan
Primary
Concomitant
Dizziness Hospitalization 4/10/2012 64 Male 7/31/2012 Japan
Primary
Concomitant
Rash Hospitalization 4/11/2012 53 Male 7/31/2012 Japan
Primary
Concomitant
Retinal Haemorrhage Other Serious 2/9/2012 50 Male 8/1/2012 Japan
Primary
Concomitant
Rash Erythematous Hospitalization 6/5/2012 58 Male 8/1/2012 Japan
Primary
Concomitant

Drug Data