Loxonin combined with Tegretol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Drug Interaction Other Serious 6/14/2005 Female 95 lb 1/18/2006 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 6/8/2004 Female 2/10/2006 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/5/2005 38 Male 2/15/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Rash Other Serious 6/8/2004 Female 2/17/2006 Physician Japan
Primary
Secondary
Concomitant
Rash 6/8/2004 Female 130 lb 3/7/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/14/2005 25 Female 3/15/2006 Physician Japan
Primary
Secondary
Concomitant
Breast Cancer Other Serious 6/14/2005 Female 95 lb 4/11/2006 Physician Japan
Primary
Concomitant
Loss Of Consciousness Other Serious 3/1/2006 78 Female 4/12/2006 Physician Japan
Primary
Concomitant
Loss Of Consciousness Other Serious 3/1/2006 78 Female 4/23/2006 Japan
Primary
Concomitant
Loss Of Consciousness Other Serious 3/1/2006 78 Female 5/31/2006 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/14/2005 25 Female 6/16/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 5/9/2006 47 Male 172 lb 9/1/2006 Physician Japan
Primary
Concomitant
Completed Suicide Death 8/27/2006 70 Female 9/5/2006 Pharmacist Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 5/9/2006 47 Male 172 lb 9/5/2006 Physician Japan
Primary
Secondary
Concomitant
Completed Suicide Death 8/27/2006 70 Female 9/7/2006 Pharmacist Japan
Primary
Concomitant
Blood Potassium Decreased Other Serious 94 Female 9/11/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 5/9/2006 47 Male 172 lb 9/15/2006 Physician Japan
Primary
Secondary
Concomitant
Pain Hospitalization 3/17/2006 41 Female 11/21/2006 Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 1/2/2007 66 Male 1/29/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 66 Male 2/9/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Uterine Neoplasm Hospitalization 12/1/2006 72 Female 115 lb 2/15/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/21/2006 70 Male 132 lb 6/29/2007 Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 8/30/2006 70 Male 132 lb 7/5/2007 Physician Japan
Primary
Secondary
Concomitant
Sepsis Death 70 Male 132 lb 7/20/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 9/23/2006 70 Male 7/20/2007 Physician Japan
Primary
Secondary
Renal Failure Acute Life Threatening 5/1/2007 Male 123 lb 7/20/2007 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 9/1/2006 70 Male 7/24/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 9/1/2006 70 Male 7/26/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 9/23/2006 70 Male 132 lb 7/31/2007 Physician Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 9/23/2006 70 Male 7/31/2007 Physician Japan
Primary
Secondary
Stevens-johnson Syndrome Death 9/23/2006 70 Male 132 lb 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 9/23/2006 70 Male 8/6/2007 Physician Japan
Primary
Secondary
Stevens-johnson Syndrome Death 9/23/2006 70 Male 8/7/2007 Physician Japan
Primary
Secondary
Pulmonary Alveolar Haemorrhage Life Threatening 7/1/2007 78 Male 127 lb 9/10/2007 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 7/1/2007 78 Male 127 lb 10/5/2007 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 10/1/2007 50 Female 10/27/2007 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/21/2007 73 Male 137 lb 11/19/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 10/19/2007 94 Female 95 lb 12/18/2007 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 10/1/2007 50 Female 12/27/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 10/9/2007 40 Male 12/28/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 5/1/2007 Male 123 lb 1/18/2008 Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 6/21/2007 73 Male 137 lb 1/28/2008 Physician Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 11/23/2007 75 Female 139 lb 2/6/2008 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 3/1/2008 Male 5/23/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/6/2007 76 Female 71 lb 5/23/2008 Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 1/1/2007 70 Male 5/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 4/1/2006 Male 112 lb 5/30/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 6/20/2004 Male 110 lb 7/7/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 6/20/2004 Male 110 lb 7/21/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 4/1/2006 Male 112 lb 7/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 4/1/2006 Male 112 lb 8/7/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 6/14/2008 Female 159 lb 8/14/2008 Physician Japan
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Hospitalization 6/14/2008 Female 159 lb 9/2/2008 Physician Japan
Primary
Concomitant
Hearing Impaired Other Serious 38 Male 11/14/2008 Physician Japan
Primary
Concomitant
Wound Complication Hospitalization 10/14/2008 Male 11/27/2008 Physician Japan
Primary
Concomitant
Wound Complication Hospitalization 10/14/2008 Male 12/4/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis 9/1/2006 70 Male 7/30/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 12/5/2008 Male 139 lb 2/3/2009 Physician Japan
Primary
Concomitant
Viral Skin Infection Hospitalization 11/1/2008 Male 2/3/2009 Pharmacist Japan
Primary
Concomitant
Renal Disorder Hospitalization 12/4/2008 75 Female 2/23/2009 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 1/17/2009 Female 97 lb 4/6/2009 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/17/2009 Female 97 lb 4/8/2009 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/17/2009 Female 97 lb 4/13/2009 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/17/2009 Female 97 lb 4/20/2009 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/17/2009 Female 97 lb 6/20/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/17/2009 Female 97 lb 6/30/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 1/12/2009 85 7/27/2009 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/27/2007 56 Female 7/30/2009 Physician Japan
Primary
Concomitant
Feeling Abnormal Other Serious 77 Female 7/31/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious 77 Female 8/7/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 1/12/2009 84 8/19/2009 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 55 Male 121 lb 9/8/2009 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 55 Male 121 lb 10/5/2009 Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2009 Female 53 lb 10/9/2009 Physician Japan
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 5/17/2009 Female 10/12/2009 Other Health Professional Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2009 Female 53 lb 11/5/2009 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 8/17/2009 43 Male 11/9/2009 Physician Japan
Primary
Concomitant
Trigeminal Neuralgia Other Serious 10/1/2009 48 Male 11/24/2009 Pharmacist Japan
Primary
Concomitant
Trigeminal Neuralgia Other Serious 10/1/2009 48 Male 12/10/2009 Pharmacist Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 1/1/2009 Male 168 lb 12/22/2009 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/29/2009 Female 165 lb 1/11/2010 Pharmacist Japan
Primary
Concomitant
Hypoacusis Other Serious 36 Male 1/18/2010 Pharmacist Japan
Primary
Concomitant
Pyrexia Other Serious 3/6/2007 Female 71 lb 1/18/2010 Japan
Primary
Secondary
Concomitant
Rash Other Serious 3/16/2008 Female 123 lb 2/22/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 3/6/2007 Female 71 lb 2/26/2010 Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Other Serious 6/30/2009 79 Male 84 lb 3/22/2010 Physician Japan
Primary
Concomitant
Uterine Cancer Other Serious 5/1/2006 55 Male 4/8/2010 Physician Japan
Primary
Concomitant
Interacting
Stomatitis Other Serious 5/2/2009 75 Male 49 lb 5/28/2010 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 2/1/2010 30 Male 128 lb 6/1/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 5/2/2009 75 Male 49 lb 6/8/2010 Physician Japan
Primary
Secondary
Concomitant
Marrow Hyperplasia Other Serious 3/29/2010 56 Female 121 lb 6/28/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 5/2/2009 75 Male 108 lb 6/28/2010 Physician Japan
Primary
Secondary
Concomitant
Partial Seizures Other Serious 7/15/2010 79 Male 8/2/2010 Physician Japan
Primary
Concomitant
Pain Other Serious 7/15/2010 79 Male 108 lb 8/13/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/9/2000 19 Female 90 lb 8/25/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 12/3/2004 58 Male 9/17/2010 Japan
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 12/3/2004 58 Male 9/17/2010 Japan
Primary
Concomitant
Meniere's Disease 10/22/2010 57 Male 11/15/2010 Pharmacist Japan
Primary
Secondary
Drug Prescribing Error Female 134 lb 12/6/2010 Physician Japan
Primary
Concomitant
Wound Complication 1/21/2010 59 Female 115 lb 12/14/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Periodontitis 1/21/2010 59 Female 115 lb 12/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Central Obesity Other Serious 25 Male 12/19/2010 Physician Japan
Primary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 1/1/1999 76 Female 128 lb 12/23/2010 Japan
Primary
Concomitant
Pyrexia Hospitalization 10/1/2010 62 Male 12/27/2010 Physician Japan
Primary
Concomitant
Muscular Weakness Hospitalization 12/1/2010 66 Female 119 lb 12/29/2010 Physician Japan
Primary
Concomitant
Muscular Weakness Hospitalization 12/1/2010 66 Female 119 lb 1/5/2011 Physician Japan
Primary
Concomitant
Rash Hospitalization 1/1/1999 76 Female 128 lb 1/6/2011 Japan
Primary
Concomitant
Weight Decreased Life Threatening 12/4/2010 28 Female 1/14/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Decreased Appetite Death 10/18/2008 46 Female 112 lb 1/17/2011 Physician Japan
Primary
Concomitant
Blood Amylase Increased 12/4/2010 28 Female 1/20/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Drug Prescribing Error Female 134 lb 1/20/2011 Physician Japan
Primary
Concomitant
Sensory Disturbance Other Serious 10/18/2008 46 Female 112 lb 1/26/2011 Physician Japan
Primary
Concomitant
Anaemia Other Serious 10/18/2008 46 Female 112 lb 1/27/2011 Physician Japan
Primary
Concomitant
Nasopharyngitis Hospitalization 12/4/2007 66 Male 141 lb 2/10/2011 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 1/8/2006 18 Female 69 lb 3/7/2011 Physician Japan
Primary
Secondary
Concomitant
Arthralgia Life Threatening 1/8/2006 18 Female 69 lb 3/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 3/23/2011 63 Male 110 lb 4/18/2011 Physician Japan
Primary
Concomitant
Pruritus Generalised Other Serious 78 Female 4/21/2011 Other Health Professional Japan
Primary
Concomitant
Amnesia Hospitalization 1/8/2006 18 Female 69 lb 4/22/2011 Physician Japan
Primary
Secondary
Concomitant
No Adverse Event Other Serious 78 Female 4/28/2011 Other Health Professional Japan
Primary
Concomitant
Akathisia Disability 4/1/2011 52 Male 265 lb 5/6/2011 Physician Japan
Primary
Concomitant
Platelet Count Increased Other Serious 5/9/2011 52 Male 5/30/2011 Physician Japan
Primary
Concomitant
Dyspnoea Other Serious 5/18/2011 83 Female 5/31/2011 Physician Japan
Primary
Secondary
Hepatic Neoplasm Malignant Other Serious 6/9/2009 59 Female 108 lb 6/3/2011 Physician Japan
Primary
Concomitant
Hospitalisation Hospitalization 5/27/2011 50 Female 6/8/2011 Physician Japan
Primary
Concomitant
Dysgeusia Hospitalization 5/1/2011 36 Female 6/17/2011 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 5/26/2011 51 Female 176 lb 6/27/2011 Other Health Professional Japan
Primary
Concomitant
Viral Infection Life Threatening 10/8/2007 57 Male 205 lb 7/6/2011 Physician Japan
Primary
Concomitant
Dysgeusia Hospitalization 5/2/2011 36 Female 7/7/2011 Physician Japan
Primary
Secondary
Concomitant
Fall Other Serious 4/26/2011 56 Male 7/12/2011 Pharmacist Japan
Primary
Concomitant
Osteonecrosis Other Serious 1/21/2010 59 Female 115 lb 7/21/2011 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 11/1/2010 45 Female 93 lb 7/27/2011 Physician Japan
Primary
Concomitant
Fall Other Serious 4/26/2011 56 Male 7/28/2011 Pharmacist Japan
Primary
Concomitant
Dizziness Other Serious 4/30/2011 71 Male 8/3/2011 Pharmacist Japan
Primary
Concomitant
Fall Other Serious 4/23/2011 56 Male 8/12/2011 Pharmacist Japan
Primary
Concomitant
Incorrect Dose Administered Other Serious 4/23/2011 56 Male 8/29/2011 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/29/2011 52 Male 117 lb 9/29/2011 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 4/30/2011 71 Male 11/29/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Corneal Erosion Hospitalization 9/6/2011 36 Female 12/20/2011 Physician Japan
Primary
Concomitant
Glomerular Filtration Rate Decreased Hospitalization 3/3/2012 40 Male 3/20/2012 Pharmacist Japan
Primary
Secondary
Vomiting Life Threatening 4/30/2011 71 Male 3/27/2012 Pharmacist Japan
Primary
Concomitant
Renal Impairment Other Serious 3/5/2012 40 Male 3/27/2012 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/25/2011 80 Male 99 lb 6/5/2012 Physician Japan
Primary
Concomitant
Cardiomyopathy Hospitalization 1/1/2012 63 Male 143 lb 6/26/2012 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Hospitalization 4/1/2011 79 Male 7/12/2012 Other Health Professional Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization Male 117 lb 4/2/2013 Physician Jp
Primary
Secondary
Concomitant
Spinal Column Stenosis Hospitalization 1/2012 Male 143 lb 1/2/2013 Physician Country Not Specified
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/10/2012 51 Female 12/12/2012 Consumer Jp
Primary
Concomitant
Interstitial Lung Disease Hospitalization 11/29/2012 49 Female 2/26/2013 Physician Jp
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/26/2012 85 Female 3/6/2013 Physician Jp
Primary
Secondary
Concomitant

Drug Data