Loxonin combined with Ribavirin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Protein Urine Present Disability 10/24/2003 36 Male 9/12/2006 Physician Japan
Primary
Secondary
Concomitant
Protein Urine Present Disability 10/24/2003 36 Male 3/21/2007 Physician Japan
Primary
Secondary
Concomitant
Nephrotic Syndrome Other Serious 7/1/2003 Male 3/22/2007 Japan
Primary
Secondary
Concomitant
Renal Tubular Disorder Hospitalization 10/24/2003 36 Male 3/14/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Tubular Disorder Hospitalization 10/24/2003 36 Male 3/28/2008 Physician Japan
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 2/7/2008 Male 119 lb 12/8/2008 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 4/26/2009 62 Male 168 lb 4/27/2009 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Life Threatening 4/27/2009 62 Male 168 lb 4/29/2009 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 4/27/2009 62 Male 168 lb 4/30/2009 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 4/27/2009 62 Male 168 lb 5/14/2009 Physician Japan
Primary
Secondary
Concomitant
Compression Fracture Hospitalization 4/15/2009 Female 101 lb 5/29/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Hospitalization 4/27/2009 62 Male 168 lb 5/26/2009 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Other Serious 6/9/2009 61 Male 152 lb 6/15/2009 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 4/27/2009 62 Male 168 lb 6/25/2009 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 10/14/2008 Female 144 lb 3/31/2010 Physician Japan
Primary
Secondary
Concomitant
Retinal Haemorrhage Hospitalization 4/8/2008 55 Female 4/6/2010 Physician Japan
Primary
Secondary
Concomitant
Stress Hospitalization 4/7/2010 40 Female 101 lb 4/21/2010 Physician Japan
Primary
Secondary
Concomitant
Stress Hospitalization 4/7/2010 40 Female 101 lb 6/22/2010 Physician Japan
Primary
Secondary
Concomitant
Stress Hospitalization 4/7/2010 40 Female 101 lb 8/2/2010 Physician Japan
Primary
Secondary
Concomitant
Stress Hospitalization 4/7/2010 40 Female 101 lb 8/25/2010 Physician Japan
Primary
Secondary
Concomitant
Stress Hospitalization 4/7/2010 40 Female 101 lb 10/21/2010 Physician Japan
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 4/7/2010 40 Female 101 lb 10/29/2010 Physician Japan
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 4/7/2010 40 Female 101 lb 12/16/2010 Physician Japan
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 4/7/2010 40 Female 101 lb 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Anaemia Hospitalization 7/22/2010 75 Female 99 lb 3/8/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/7/2010 66 Male 10/20/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Artery Thrombosis Hospitalization 4/27/2009 62 Male 168 lb 2/9/2012 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 12/28/2011 40 Male 3/1/2012 Other Health Professional Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 2/19/2012 57 Male 3/7/2012 Japan
Primary
Concomitant
Decreased Appetite Other Serious 2/19/2012 57 Male 3/16/2012 Other Health Professional Japan
Primary
Concomitant
Depressive Symptom Hospitalization 2/3/2012 66 Female 3/21/2012 Other Health Professional Japan
Primary
Concomitant
Psychiatric Symptom Other Serious 2/6/2012 64 Female 3/30/2012 Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 1/20/2012 53 Female 4/2/2012 Japan
Primary
Concomitant
Renal Failure Acute Other Serious 3/15/2012 59 Male 4/3/2012 Other Health Professional Japan
Primary
Concomitant
Blood Creatinine Increased Hospitalization 2/23/2012 50 Female 4/9/2012 Other Health Professional Japan
Primary
Concomitant
Pancytopenia Other Serious 1/24/2012 59 Female 4/11/2012 Japan
Primary
Concomitant
Rash Other Serious 4/4/2012 62 Male 4/12/2012 Japan
Primary
Concomitant
Decreased Appetite Other Serious 2/19/2012 57 Male 4/18/2012 Japan
Primary
Concomitant
Rash Other Serious 4/4/2012 62 Male 4/18/2012 Other Health Professional Japan
Primary
Concomitant
Depression Hospitalization 2/27/2012 54 Female 4/20/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Other Serious 2/22/2012 66 Male 4/20/2012 Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/20/2012 36 Female 4/20/2012 Japan
Primary
Concomitant
Pancytopenia Other Serious 1/24/2012 59 Female 4/24/2012 Japan
Primary
Concomitant
Nausea Other Serious 2/16/2012 54 Female 4/26/2012 Japan
Primary
Concomitant
Decreased Appetite Hospitalization 2/2/2012 59 Female 4/30/2012 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 3/26/2012 61 Male 5/7/2012 Other Health Professional Japan
Primary
Concomitant
Renal Impairment 3/26/2012 61 Male 5/8/2012 Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 3/23/2012 38 Male 5/10/2012 Japan
Primary
Concomitant
Depressive Symptom Other Serious 2/3/2012 66 Female 5/14/2012 Japan
Primary
Concomitant
Rash Hospitalization 4/11/2012 63 Female 5/16/2012 Japan
Primary
Concomitant
Pancytopenia Other Serious 2/9/2012 50 Male 5/17/2012 Japan
Primary
Concomitant
Generalised Erythema Hospitalization 4/25/2012 45 Male 5/18/2012 Japan
Primary
Concomitant
Skin Exfoliation Other Serious 5/2/2012 62 Female 5/18/2012 Japan
Primary
Concomitant
Pancytopenia Other Serious 1/24/2012 59 Female 5/23/2012 Japan
Primary
Concomitant
Pancytopenia Other Serious 2/9/2012 50 Male 5/23/2012 Other Health Professional Japan
Primary
Concomitant
Blood Uric Acid Increased Hospitalization 5/8/2012 47 Male 5/25/2012 Other Health Professional Japan
Primary
Concomitant
Hyperuricaemia Hospitalization 2/22/2012 66 Male 5/25/2012 Other Health Professional Japan
Primary
Concomitant
Rash Other Serious 3/17/2012 48 Male 5/25/2012 Other Health Professional Japan
Primary
Concomitant
Depression Hospitalization 2/27/2012 54 Female 5/29/2012 Other Health Professional Japan
Primary
Concomitant
Arrhythmia Life Threatening 5/19/2012 Male 6/1/2012 Other Health Professional Japan
Primary
Concomitant
Impulsive Behaviour Hospitalization 2/6/2012 64 Female 6/1/2012 Other Health Professional Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 4/17/2012 39 Male 6/1/2012 Japan
Primary
Concomitant
Toxic Skin Eruption Other Serious 3/5/2012 68 Female 6/3/2012 Japan
Primary
Concomitant
Rash Hospitalization 4/11/2012 53 Male 6/6/2012 Japan
Primary
Concomitant
Renal Tubular Necrosis Other Serious 3/15/2012 59 Male 6/6/2012 Japan
Primary
Concomitant
Nausea Other Serious 2/16/2012 54 Female 6/6/2012 Japan
Primary
Concomitant
Asthenia Other Serious 2/19/2012 57 Male 6/8/2012 Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 3/31/2012 57 Male 147 lb 5/30/2012 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/24/2012 59 Female 6/14/2012 Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 5/15/2012 Male 6/18/2012 Other Health Professional Japan
Primary
Concomitant
Cardiac Failure Life Threatening 5/15/2012 Male 6/18/2012 Other Health Professional Japan
Primary
Concomitant
Blood Glucose Increased Hospitalization Female 6/20/2012 Other Health Professional Japan
Primary
Concomitant
Vomiting Hospitalization 5/25/2012 60 Female 6/20/2012 Other Health Professional Japan
Primary
Concomitant
Bronchitis Hospitalization 4/20/2012 69 Female 6/21/2012 Other Health Professional Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 3/31/2012 57 Male 147 lb 6/12/2012 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 2/2/2012 59 Female 6/26/2012 Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Other Serious 1/20/2012 53 Female 6/26/2012 Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 1/20/2012 53 Female 6/29/2012 Japan
Primary
Concomitant
Erythema Multiforme Hospitalization 5/2/2012 67 Female 6/29/2012 Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/20/2012 36 Female 6/29/2012 Other Health Professional Japan
Primary
Concomitant
Haemoglobin Decreased Hospitalization 6/14/2012 62 Female 7/2/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/5/2012 68 Female 7/2/2012 Japan
Primary
Concomitant
Decreased Appetite Hospitalization 50 Female 7/2/2012 Other Health Professional Japan
Primary
Concomitant
Herpes Zoster Other Serious 5/8/2012 65 Female 7/2/2012 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/14/2012 62 Female 7/6/2012 Other Health Professional Japan
Primary
Concomitant
Erythema Hospitalization 4/27/2012 56 Male 7/10/2012 Japan
Primary
Concomitant
Off Label Use Other Serious 5/1/2012 59 Female 7/11/2012 Other Health Professional Japan
Primary
Concomitant
Renal Disorder 5/28/2012 70 Female 7/13/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Other Serious 5/1/2012 72 Male 7/19/2012 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/24/2012 59 Female 7/20/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Hospitalization 1/13/2012 54 Female 7/20/2012 Japan
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 5/17/2012 63 Male 7/20/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Other Serious 1/13/2012 54 Female 7/23/2012 Japan
Primary
Concomitant
Pyelonephritis Hospitalization 5/25/2012 70 Male 7/23/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/20/2012 36 Female 7/24/2012 Japan
Primary
Concomitant
Erythema Multiforme Hospitalization Female 7/27/2012 Other Health Professional Japan
Primary
Concomitant
Retinal Haemorrhage Other Serious 2/9/2012 50 Male 8/1/2012 Japan
Primary
Concomitant
Rash Erythematous Hospitalization 6/5/2012 58 Male 8/1/2012 Japan
Primary
Concomitant
Drug Eruption Other Serious 4/11/2012 63 Female 8/1/2012 Japan
Primary
Concomitant
Haemorrhoids Hospitalization 4/20/2012 67 Male 8/6/2012 Japan
Primary
Concomitant
Rash Erythematous Hospitalization 6/5/2012 58 Male 8/8/2012 Japan
Primary
Concomitant
Rash Erythematous Hospitalization 6/5/2012 58 Male 8/9/2012 Japan
Primary
Concomitant
Syncope Hospitalization 7/12/2012 47 Male 8/10/2012 Japan
Primary
Concomitant
Decreased Appetite Hospitalization 7/18/2012 66 Male 8/10/2012 Japan
Primary
Concomitant
Skin Exfoliation Other Serious 5/2/2012 62 Female 8/10/2012 Japan
Primary
Concomitant
Rash Hospitalization 7/30/2012 47 Male 8/10/2012 Japan
Primary
Concomitant
Cough Other Serious 7/10/2012 47 Female 8/10/2012 Japan
Primary
Concomitant
Renal Impairment Other Serious 6/26/2012 65 Male 8/13/2012 Other Health Professional Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 2/16/2012 63 Female 8/13/2012 Japan
Primary
Concomitant
Rash Other Serious 6/25/2012 65 Female 8/13/2012 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 5/8/2012 65 Female 8/13/2012 Japan
Primary
Concomitant
Decreased Appetite Hospitalization 4/11/2012 70 Female 8/13/2012 Other Health Professional Japan
Primary
Concomitant
Retinal Haemorrhage Other Serious 2/9/2012 50 Male 8/14/2012 Japan
Primary
Concomitant
Blood Uric Acid Increased Other Serious 6/18/2012 63 Male 8/14/2012 Other Health Professional Japan
Primary
Concomitant
Insomnia Hospitalization 2/16/2012 54 Female 8/24/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/16/2012 54 Female 11/20/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Other Serious 3/17/2012 48 Male 12/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 8/10/2012 64 Male 9/13/2012 Other Health Professional Jp
Primary
Concomitant
Hepatic Encephalopathy Other Serious 7/24/2012 49 Male 9/7/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 2/23/2012 9/13/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 4/17/2012 9/14/2012 Other Health Professional Jp
Primary
Concomitant
Depression Other Serious 3/21/2012 69 Male 9/17/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Malaise Hospitalization 5/8/2012 47 Male 11/8/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 5/15/2012 51 Male 10/22/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinopathy Other Serious 7/26/2012 57 Male 9/20/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Other Serious 7/21/2012 65 Female 9/25/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Nausea Other Serious 3/17/2012 44 Female 10/4/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Synovial Cyst Hospitalization 8/22/2012 42 Male 10/8/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 10/9/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/20/2012 36 Female 10/9/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Drug Eruption Other Serious 10/4/2012 70 Male 11/15/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinal Haemorrhage Other Serious 8/14/2012 64 Male 12/19/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Hepatic Cancer Hospitalization 5/1/2012 60 Male 10/17/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 9/6/2012 51 Male 12/3/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 8/16/2012 73 Male 11/16/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Pruritus Hospitalization 8/15/2012 42 Male 10/22/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinal Haemorrhage Other Serious 5/14/2012 69 Male 10/25/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 3/2012 59 Male 10/26/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Depression Other Serious 8/28/2012 45 Male 10/29/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/11/2012 48 Female 11/9/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 7/17/2012 68 Female 11/12/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/24/2012 59 Female 11/14/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/23/2012 53 Female 11/14/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/26/2012 62 Female 11/27/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 6/6/2012 57 Female 11/21/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 5/14/2012 65 Male 11/27/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 9/19/2012 62 Male 12/21/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/9/2012 66 Male 12/27/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 11/10/2012 62 Female 12/11/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/3/2012 66 Male 12/18/2012 Other Health Professional Jp
Primary
Secondary
Concomitant

Drug Data