Loxonin combined with Rabeprazole Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 8/3/2007 Consumer Japan
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 8/9/2007 Consumer Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/1/2007 Female 8/10/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/1/2007 Female 8/15/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Urticaria Hospitalization 2/25/2007 Female 9/12/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/1/2007 Female 9/14/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 9/24/2007 73 Male 150 lb 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 9/24/2007 73 Male 150 lb 11/6/2007 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Other Serious 12/25/2006 31 Female 117 lb 12/21/2007 Physician Japan
Primary
Concomitant
Sepsis Death 11/6/2007 Male 12/21/2007 Consumer United Kingdom
Primary
Concomitant
Vasculitis Other Serious 12/1/2007 63 Female 121 lb 1/28/2008 Physician Japan
Primary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 3/3/2008 67 Male 4/30/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/29/2008 67 Male 6/9/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/29/2008 67 Male 6/12/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Muscle Strain Hospitalization 9/22/2003 67 Male 123 lb 6/13/2008 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/2/2007 Female 6/20/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Disability 5/29/2007 74 Female 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Jaundice Other Serious 5/14/2008 Male 144 lb 6/30/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/31/2008 Male 164 lb 9/5/2008 Physician Japan
Primary
Secondary
Concomitant
Delirium Other Serious 8/31/2008 79 Female 9/12/2008 Physician Japan
Primary
Concomitant
Delirium Other Serious 8/31/2008 79 Female 9/29/2008 Physician Japan
Primary
Concomitant
Tuberculous Pleurisy Hospitalization 7/30/2008 Female 101 lb 10/10/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Iv Hospitalization 7/15/2008 54 Male 108 lb 10/17/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 8/13/2008 Female 141 lb 10/20/2008 Physician Japan
Primary
Concomitant
Septic Embolus Death 9/29/2008 Male 10/20/2008 Physician Japan
Primary
Secondary
Concomitant
Sudden Hearing Loss Hospitalization 10/15/2008 Female 97 lb 10/29/2008 Other Health Professional Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 10/19/2008 Female 125 lb 10/31/2008 Japan
Primary
Concomitant
Sudden Hearing Loss Hospitalization 10/15/2008 Female 97 lb 11/7/2008 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/10/2008 Male 162 lb 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 10/1/2004 Female 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 10/19/2008 Female 125 lb 11/11/2008 Japan
Primary
Concomitant
Pain In Jaw Other Serious 6/1/2008 Female 11/11/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/1/2008 Male 143 lb 11/18/2008 Physician Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 6/1/2008 Female 115 lb 11/19/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 8/13/2008 Female 134 lb 11/20/2008 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 10/19/2008 Female 125 lb 11/20/2008 Japan
Primary
Concomitant
Venous Thrombosis Hospitalization 10/3/2008 55 Male 11/20/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Disability 5/29/2007 73 Female 12/10/2008 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 10/31/2008 65 Female 112 lb 12/12/2008 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/10/2008 Male 162 lb 12/16/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 7/30/2008 Female 101 lb 12/31/2008 Physician Japan
Primary
Secondary
Concomitant
Vena Cava Thrombosis Hospitalization 9/1/2008 Male 151 lb 12/29/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 8/13/2008 Female 134 lb 1/15/2009 Physician Japan
Primary
Concomitant
Ileus Paralytic Other Serious 11/5/2008 1/21/2009 Other Health Professional Japan
Primary
Concomitant
Septic Shock Death 5/5/2008 59 Male 106 lb 1/23/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 8/13/2008 Female 134 lb 5/18/2009 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Life Threatening 3/1/2009 65 Male 141 lb 5/20/2009 Physician Japan
Primary
Concomitant
Renal Haemorrhage Other Serious 5/7/2008 70 Male 5/26/2009 Physician Japan
Primary
Concomitant
Nausea Hospitalization 12/17/2009 Female 1/14/2010 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 12/7/2009 Male 154 lb 1/18/2010 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 12/7/2009 Male 154 lb 1/21/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6/22/2010 78 Female 117 lb 7/16/2010 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 5/25/2009 7/16/2010 Physician Japan
Primary
Concomitant
Primary Cerebellar Degeneration Other Serious 9/18/2008 67 Female 110 lb 7/19/2010 Physician Japan
Primary
Secondary
Concomitant
Chemotherapy Other Serious 10/1/2009 74 Female 82 lb 7/22/2010 Physician Japan
Primary
Concomitant
Pain Other Serious 11/16/2009 74 Male 152 lb 7/22/2010 Physician Japan
Primary
Concomitant
Skin Ulcer Hospitalization 10/1/2009 49 Female 7/23/2010 Physician Japan
Primary
Concomitant
Tachypnoea Death 4/2/2010 66 Female 93 lb 7/27/2010 Physician Japan
Primary
Concomitant
Urine Output Decreased Other Serious 4/2/2010 78 Male 110 lb 7/30/2010 Pharmacist Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/1/2009 81 Male 134 lb 7/31/2010 Physician Japan
Primary
Concomitant
Nausea Other Serious 4/26/2010 65 Female 86 lb 8/6/2010 Pharmacist Japan
Primary
Concomitant
Rib Fracture Other Serious 9/18/2008 67 Female 110 lb 8/12/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 6/1/2010 82 Female 97 lb 8/12/2010 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 8/3/2010 42 90 lb 8/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sinus Bradycardia Life Threatening 6/9/2009 69 Male 157 lb 8/18/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Life Threatening 6/18/2010 78 Female 117 lb 8/20/2010 Physician Japan
Primary
Concomitant
Subdural Haematoma Other Serious 6/8/2009 82 Female 8/20/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 6/1/2010 82 Female 97 lb 8/21/2010 Physician Japan
Primary
Concomitant
Stomatitis Life Threatening 7/13/2010 81 Female 92 lb 8/24/2010 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis 10/14/2009 49 Female 117 lb 8/27/2010 Physician Japan
Primary
Concomitant
Pleurisy Hospitalization 3/31/2009 1/20/2011 Other Health Professional Japan
Primary
Concomitant
Cholangitis Acute Life Threatening 6/1/2010 82 Female 97 lb 5/16/2011 Consumer Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 4/13/2011 72 Male 112 lb 5/24/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 5/11/2011 77 Male 5/31/2011 Physician Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Death 3/30/2011 73 Male 120 lb 6/1/2011 Physician Japan
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Death 8/21/2010 48 Female 95 lb 6/2/2011 Physician Japan
Primary
Secondary
Concomitant
Cholangitis Life Threatening 7/21/2010 55 Male 176 lb 6/2/2011 Physician Japan
Primary
Concomitant
Hypothyroidism Hospitalization 7/29/2009 67 Female 99 lb 6/3/2011 Physician Japan
Primary
Concomitant
Hepatic Failure Hospitalization 7/4/2010 86 Female 104 lb 6/3/2011 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 6/9/2009 59 Female 108 lb 6/3/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/11/2011 77 Male 6/6/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Death 3/30/2011 73 Male 120 lb 6/14/2011 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Death 5/18/2011 74 Female 6/16/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 5/11/2011 77 Male 6/23/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 5/11/2011 77 Male 6/30/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Influenzal Death 1/16/2011 54 Female 106 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Disability 8/12/2010 70 Male 104 lb 7/5/2011 Other Health Professional Japan
Primary
Concomitant
Viral Infection Life Threatening 10/8/2007 57 Male 205 lb 7/6/2011 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 11/22/2010 67 Male 7/12/2011 Physician Japan
Primary
Secondary
Concomitant
Erythema Life Threatening 5/20/2011 75 Male 111 lb 7/12/2011 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Death 8/10/2010 77 Male 95 lb 7/12/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Death 8/31/2010 61 Male 115 lb 7/11/2011 Physician Japan
Primary
Concomitant
Mesenteric Panniculitis Hospitalization 6/15/2011 72 Male 196 lb 7/18/2011 Physician Japan
Primary
Concomitant
Colitis Microscopic Other Serious 10/12/2010 60 Female 7/22/2011 Physician Japan
Primary
Secondary
Concomitant
Occult Blood Positive Other Serious 10/12/2010 60 Female 7/26/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Eruption Hospitalization 62 Female 100 lb 7/26/2011 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 1/16/2011 54 Female 106 lb 7/27/2011 Consumer Japan
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Other Serious 5/12/2010 73 Female 7/29/2011 Physician Japan
Primary
Secondary
Concomitant
Encephalitis Fungal Death Male 139 lb 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Influenza Life Threatening 1/16/2011 54 Female 106 lb 8/2/2011 Consumer Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 5/17/2011 74 Female 8/3/2011 Physician Japan
Primary
Secondary
Concomitant
Mesenteric Panniculitis Hospitalization 6/15/2011 72 Male 196 lb 8/3/2011 Physician Japan
Primary
Concomitant
Occult Blood Positive 10/12/2010 60 Female 8/8/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 5/13/2011 64 Male 8/8/2011 Physician Japan
Primary
Secondary
Concomitant
Left Ventricular Hypertrophy Hospitalization 5/27/2011 61 Male 105 lb 8/10/2011 Consumer Japan
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 7/17/2011 70 Female 84 lb 8/11/2011 Physician Japan
Primary
Concomitant
Organising Pneumonia Hospitalization 3/5/2010 63 Female 117 lb 8/15/2011 Physician Japan
Primary
Secondary
Concomitant
Small Intestine Carcinoma Hospitalization 6/15/2011 72 Male 196 lb 8/16/2011 Physician Japan
Primary
Concomitant
Herpes Zoster Other Serious 7/10/2011 59 Female 8/19/2011 Physician Japan
Primary
Concomitant
Spinal Compression Fracture Other Serious 7/1/2011 77 Female 88 lb 8/30/2011 Physician Japan
Primary
Concomitant
Faeces Discoloured Death 5/25/2011 89 Female 101 lb 8/31/2011 Physician Japan
Primary
Concomitant
Infection Death 8/21/2010 48 Female 95 lb 9/1/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Death 8/17/2010 36 Female 9/10/2011 Physician Japan
Primary
Secondary
Concomitant
Hypocoagulable State Death 4/12/2010 60 Male 9/12/2011 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 4/12/2010 60 Male 9/13/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Death 4/12/2010 60 Male 9/13/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Death 1/27/2011 74 Male 110 lb 9/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Herpes Zoster 7/10/2011 59 Female 9/16/2011 Physician Japan
Primary
Concomitant
Constipation Life Threatening 9/13/2010 56 Male 126 lb 9/19/2011 Physician Japan
Primary
Concomitant
Hypocoagulable State Hospitalization 4/12/2010 60 Male 9/21/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Constipation Other Serious 4/12/2010 60 Male 9/22/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Hospitalization 4/12/2010 60 Male 9/23/2011 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Life Threatening 10/20/2008 76 Male 154 lb 9/23/2011 Other Health Professional Japan
Primary
Concomitant
Organising Pneumonia Hospitalization 3/1/2010 63 Female 117 lb 9/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Hospitalization 4/12/2010 60 Male 9/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Enterocolitis Hospitalization 12/24/2010 19 Male 117 lb 9/28/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 10/10/2009 87 Female 158 lb 9/28/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 9/20/2011 39 Female 9/30/2011 Physician Japan
Primary
Concomitant
Respiratory Depression Other Serious 6/17/2011 79 Female 101 lb 10/6/2011 Physician Japan
Primary
Secondary
Concomitant
Dementia Other Serious 9/28/2010 76 Male 121 lb 10/7/2011 Physician Japan
Primary
Secondary
Concomitant
Dementia Other Serious 9/28/2010 76 Male 121 lb 10/7/2011 Physician Japan
Primary
Secondary
Concomitant
Pruritus Other Serious 9/21/2010 65 Female 84 lb 10/7/2011 Physician Japan
Primary
Concomitant
Neutropenia Hospitalization 4/12/2010 60 Male 10/14/2011 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 1/27/2011 74 Male 110 lb 10/20/2011 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 9/20/2011 39 Male 161 lb 10/24/2011 Physician Japan
Primary
Concomitant
Chest Discomfort Hospitalization 8/2/2010 89 Male 126 lb 10/25/2011 Physician Japan
Primary
Secondary
Concomitant
Metastases To Liver Hospitalization 12/1/2010 66 Male 112 lb 10/27/2011 Consumer Japan
Primary
Concomitant
Multi-organ Failure Death 9/29/2011 89 Male 119 lb 11/1/2011 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/31/2011 77 Female 110 lb 11/3/2011 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Death 10/21/2011 57 Female 93 lb 11/7/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Other Serious 10/1/2011 65 Male 157 lb 11/9/2011 Physician Japan
Primary
Secondary
Concomitant
Delirium Other Serious 6/20/2011 71 Male 11/14/2011 Physician Japan
Primary
Secondary
Concomitant
Metastases To Liver Death 12/1/2010 66 Male 112 lb 11/14/2011 Physician Japan
Primary
Concomitant
Delirium Other Serious 6/20/2011 71 Male 11/18/2011 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Death 10/21/2011 57 Female 93 lb 11/18/2011 Physician Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 9/20/2011 39 Male 161 lb 11/21/2011 Physician Japan
Primary
Concomitant
Dyspnoea Death 5/19/2011 83 Male 132 lb 11/28/2011 Physician Japan
Primary
Concomitant
Haemorrhagic Ascites Hospitalization 11/7/2011 79 Female 168 lb 11/25/2011 Physician Japan
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 10/1/2011 65 Male 157 lb 11/28/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/31/2011 77 Female 110 lb 11/28/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data