Loxonin combined with Pydoxal

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
B-cell Lymphoma Hospitalization 4/1/2006 Female 106 lb 5/2/2006 Physician Japan
Primary
Secondary
Concomitant
B-cell Lymphoma Stage Iv Life Threatening 3/1/2006 Female 90 lb 5/23/2006 Physician Japan
Primary
Secondary
Concomitant
B-cell Lymphoma Stage Iv Life Threatening 3/1/2006 Female 90 lb 6/16/2006 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 6/2/2006 Male 128 lb 12/18/2006 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 12/21/2006 Female 97 lb 2/5/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 12/21/2006 Female 97 lb 2/12/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/22/2006 Female 75 lb 2/14/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 10/15/2006 Male 168 lb 2/28/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 10/15/2006 Male 168 lb 4/11/2007 Physician Japan
Primary
Secondary
Concomitant
Uterine Leiomyoma Life Threatening 3/1/2006 Female 90 lb 4/17/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 10/15/2006 Male 168 lb 5/7/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Other Serious 9/7/2006 71 Male 168 lb 5/17/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 12/21/2006 Female 97 lb 5/23/2007 Physician Japan
Primary
Secondary
Concomitant
Nephrotic Syndrome Hospitalization 4/12/2007 Male 101 lb 6/4/2007 Physician Japan
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 5/23/2007 64 Male 6/8/2007 Consumer Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/23/2007 64 Male 117 lb 7/3/2007 Consumer Japan
Primary
Concomitant
Nephrotic Syndrome Hospitalization 4/12/2007 Male 101 lb 7/24/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Other Serious 9/7/2006 71 Male 168 lb 9/17/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 10/15/2006 Male 168 lb 9/21/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 7/1/2007 68 Female 104 lb 9/28/2007 Physician Japan
Primary
Concomitant
Renal Disorder Hospitalization 10/15/2006 Male 159 lb 10/26/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 7/20/2007 68 Female 104 lb 11/2/2007 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/12/2007 64 Male 117 lb 11/9/2007 Consumer Japan
Primary
Concomitant
Rheumatoid Arthritis Death 12/3/2007 Female 2/13/2008 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 1/8/2008 Female 115 lb 4/2/2008 Physician Japan
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Hospitalization 6/21/2007 Female 90 lb 5/30/2008 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2008 Male 6/6/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2008 Male 6/26/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/22/2006 64 Female 7/7/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/22/2006 64 Female 7/10/2008 Japan
Primary
Secondary
Concomitant
Intervertebral Disc Protrusion Hospitalization 1/1/2003 56 Female 9/15/2008 Pharmacist Japan
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 1/1/2003 56 Female 9/24/2008 Pharmacist Japan
Primary
Concomitant
Rectal Ulcer Other Serious 6/24/2008 Female 132 lb 9/29/2008 Physician Japan
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 6/24/2008 Female 132 lb 10/13/2008 Physician Japan
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Hospitalization 6/21/2007 Female 90 lb 11/14/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 12/20/2008 76 Male 1/5/2009 Physician Japan
Primary
Concomitant
Pneumonia Aspiration Death 12/18/2008 Male 3/2/2009 Physician Japan
Primary
Concomitant
Mycobacterium Avium Complex Infection Hospitalization 6/21/2007 Female 90 lb 3/6/2009 Physician Japan
Primary
Secondary
Concomitant
Shock Death 9/20/2008 Male 3/23/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 9/16/2008 68 Female 143 lb 4/1/2009 Physician Japan
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Hospitalization 3/3/2009 Male 6/19/2009 Physician Japan
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Life Threatening 3/3/2009 Male 6/30/2009 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Death 1/25/2008 Female 9/21/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 1/1/2009 Female 10/21/2009 Physician Japan
Primary
Secondary
Concomitant
Hepatic Steatosis Hospitalization 9/1/2009 Female 10/30/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/1/2009 Female 11/23/2009 Physician Japan
Primary
Secondary
Concomitant
Hepatic Steatosis Hospitalization 9/1/2009 Female 12/10/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/3/2009 Female 121 lb 1/19/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/3/2009 Female 134 lb 1/20/2010 Other Health Professional Japan
Primary
Concomitant
Knee Arthroplasty Other Serious 10/2/2009 Female 203 lb 1/28/2010 Pharmacist Japan
Primary
Concomitant
Subdural Haematoma Hospitalization 9/17/2008 Female 93 lb 2/4/2010 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 3/18/2009 Female 105 lb 2/5/2010 Physician Japan
Primary
Concomitant
Nausea Hospitalization 10/12/2009 Female 101 lb 2/10/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Life Threatening 11/1/2009 Female 148 lb 2/15/2010 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 9/6/2008 Female 126 lb 2/23/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/3/2009 Female 121 lb 2/25/2010 Physician Japan
Primary
Concomitant
Subdural Haematoma Hospitalization 9/17/2008 Female 93 lb 2/26/2010 Physician Japan
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 1/30/2010 Female 86 lb 3/8/2010 Japan
Primary
Concomitant
Nausea Hospitalization 10/12/2009 Female 101 lb 3/16/2010 Physician Japan
Primary
Concomitant
Melaena Hospitalization 7/15/2009 Female 165 lb 3/17/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/16/2008 68 Female 143 lb 3/23/2010 Physician Japan
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 1/30/2010 69 Female 86 lb 4/9/2010 Japan
Primary
Concomitant
Platelet Count Decreased Life Threatening 11/1/2009 70 Female 148 lb 4/16/2010 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 9/7/2006 71 Male 168 lb 4/26/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Nausea Death 7/17/2009 37 Female 106 lb 5/3/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 8/24/2009 60 Female 5/5/2010 Physician Japan
Primary
Secondary
Concomitant
Purpura Other Serious 5/3/2010 63 Female 104 lb 5/18/2010 Pharmacist Japan
Primary
Concomitant
Nausea Death 7/17/2009 37 Female 106 lb 5/25/2010 Physician Japan
Primary
Concomitant
Lip And/or Oral Cavity Cancer Hospitalization 9/1/2009 66 Female 6/2/2010 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Other Serious 4/22/2010 62 Male 121 lb 6/25/2010 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 7/19/2008 72 Female 93 lb 7/6/2010 Physician Japan
Primary
Secondary
Concomitant
Volvulus Other Serious 1/1/2009 79 Male 7/15/2010 Physician Japan
Primary
Concomitant
Hepatitis Fulminant Hospitalization 3/25/2010 76 Male 7/23/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Interstitial Lung Disease Hospitalization 6/8/2010 49 Female 143 lb 7/27/2010 Physician Japan
Primary
Concomitant
Hepatitis Fulminant Hospitalization 3/25/2010 76 Male 8/4/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Breast Cancer Female Life Threatening 4/26/2010 71 Female 165 lb 8/10/2010 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/8/2010 49 Female 143 lb 8/12/2010 Physician Japan
Primary
Concomitant
Breast Cancer Female Life Threatening 4/26/2010 71 Female 165 lb 9/1/2010 Other Health Professional Japan
Primary
Concomitant
Volvulus Hospitalization 3/4/2009 79 Male 9/4/2010 Physician Japan
Primary
Concomitant
Retinal Haemorrhage Other Serious 4/15/2010 63 Female 104 lb 9/10/2010 Pharmacist Japan
Primary
Concomitant
Pyrexia Other Serious 1/29/2008 52 Female 9/27/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 7/19/2008 72 Female 93 lb 10/5/2010 Physician Japan
Primary
Secondary
Concomitant
Lip And/or Oral Cavity Cancer Hospitalization 9/1/2009 66 Female 10/13/2010 Physician Japan
Primary
Concomitant
Lip And/or Oral Cavity Cancer Hospitalization 8/27/2009 66 Female 10/27/2010 Physician Japan
Primary
Concomitant
Metastases To Central Nervous System Hospitalization 9/15/2010 10/29/2010 Physician Japan
Primary
Concomitant
Retinal Haemorrhage Other Serious 4/15/2010 63 Female 104 lb 11/12/2010 Physician Japan
Primary
Concomitant
Unresponsive To Stimuli Other Serious 9/15/2010 79 Female 11/19/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 9/15/2010 11/30/2010 Physician Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 9/15/2010 11/30/2010 Physician Japan
Primary
Concomitant
Subdural Haematoma Hospitalization 9/17/2008 70 Female 93 lb 12/3/2010 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/3/2009 60 Female 121 lb 12/13/2010 Physician Japan
Primary
Concomitant
Urticaria Other Serious 9/15/2009 64 Female 134 lb 12/16/2010 Physician Japan
Primary
Concomitant
Radiation Oesophagitis Hospitalization 7/1/2009 35 Female 95 lb 12/23/2010 Physician Japan
Primary
Concomitant
Decreased Appetite Other Serious 2/22/2010 72 Male 123 lb 1/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Melaena Hospitalization 7/15/2009 49 Female 165 lb 1/19/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 10/3/2010 66 Female 143 lb 1/20/2011 Other Health Professional Japan
Primary
Concomitant
Ovarian Cancer Hospitalization 11/6/2009 60 Female 121 lb 1/20/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Test Positive Death 5/1/2010 72 Female 176 lb 1/21/2011 Physician Japan
Primary
Secondary
Concomitant
Shock Hospitalization 9/16/2008 68 Female 143 lb 1/24/2011 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 5/11/2009 85 Female 106 lb 1/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Chills Other Serious 9/15/2009 64 Female 134 lb 2/2/2011 Physician Japan
Primary
Concomitant
Pneumonia Bacterial Death 5/1/2010 72 Female 176 lb 2/8/2011 Physician Japan
Primary
Secondary
Concomitant
Ovarian Cancer Hospitalization 9/15/2009 64 Female 134 lb 2/14/2011 Physician Japan
Primary
Concomitant
Melaena Hospitalization 7/15/2009 49 Female 165 lb 2/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 10/3/2010 66 Female 143 lb 2/16/2011 Pharmacist Japan
Primary
Concomitant
Device Related Infection Hospitalization 11/6/2009 60 Female 121 lb 2/28/2011 Physician Japan
Primary
Concomitant
Decubitus Ulcer Hospitalization 5/11/2009 85 Female 106 lb 2/28/2011 Physician Japan
Primary
Secondary
Concomitant
Melaena Hospitalization 7/15/2009 49 Female 165 lb 3/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Death 7/12/2009 56 Female 99 lb 3/9/2011 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Other Serious 4/22/2010 62 Male 121 lb 3/10/2011 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/8/2010 49 Female 143 lb 3/24/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/8/2010 49 Female 143 lb 3/28/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Death 7/12/2009 56 Female 99 lb 3/28/2011 Physician Japan
Primary
Concomitant
Joint Destruction Hospitalization 9/17/2008 70 Female 93 lb 3/29/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Eruption Hospitalization 7/25/2009 37 Female 106 lb 4/5/2011 Physician Japan
Primary
Concomitant
Blood Creatinine Increased Hospitalization 4/13/2010 68 Female 93 lb 4/7/2011 Physician Japan
Primary
Secondary
Concomitant
Hypercapnia Life Threatening 8/1/2009 48 Female 148 lb 4/8/2011 Physician Japan
Primary
Concomitant
Nausea Hospitalization 8/16/2010 69 Female 90 lb 4/14/2011 Physician Japan
Primary
Secondary
Concomitant
Hypertriglyceridaemia Hospitalization 9/17/2008 70 Female 93 lb 4/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 5/26/2010 57 Female 132 lb 4/27/2011 Physician Japan
Primary
Concomitant
Cellulitis Other Serious 4/22/2010 62 Male 121 lb 4/29/2011 Physician Japan
Primary
Concomitant
Drug Eruption Hospitalization 7/25/2009 37 Female 106 lb 5/5/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 3/17/2011 80 Female 110 lb 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 12/1/2010 69 Female 6/6/2011 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/3/2009 60 Female 121 lb 6/15/2011 Physician Japan
Primary
Concomitant
Peritoneal Tuberculosis Hospitalization 12/1/2010 69 Female 6/22/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 6/8/2010 49 Female 143 lb 6/24/2011 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 5/12/2011 55 Male 160 lb 7/4/2011 Physician Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 12/1/2010 69 Female 139 lb 7/11/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 6/8/2010 49 Female 143 lb 8/12/2011 Physician Japan
Primary
Concomitant
Pneumothorax Hospitalization 11/19/2009 60 Female 8/26/2011 Physician Japan
Primary
Secondary
Concomitant
Lung Infection Death 5/6/2010 64 Female 108 lb 8/29/2011 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 5/12/2011 55 Male 160 lb 9/1/2011 Physician Japan
Primary
Concomitant
Renal Impairment Disability 12/22/2009 67 Female 93 lb 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Death 1/27/2011 74 Male 110 lb 9/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 5/6/2010 64 Female 108 lb 10/4/2011 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 5/12/2011 55 Male 160 lb 10/7/2011 Physician Japan
Primary
Concomitant
Eczema Death 7/31/2009 60 Female 10/16/2011 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 1/27/2011 74 Male 110 lb 10/20/2011 Physician Japan
Primary
Secondary
Concomitant
Ovarian Cancer Recurrent Life Threatening 11/1/2009 70 Female 148 lb 10/28/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 8/16/2010 69 Female 90 lb 11/1/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 9/26/2011 83 Female 12/5/2011 Consumer Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 8/26/2011 69 Male 154 lb 12/21/2011 Physician Japan
Primary
Secondary
Concomitant
Dyschezia Other Serious 11/14/2011 52 Male 132 lb 12/27/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 10/6/2011 69 Male 115 lb 1/3/2012 Physician Japan
Primary
Secondary
Concomitant
Ovarian Cancer Recurrent Death 4/15/2010 63 Female 104 lb 1/18/2012 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 12/22/2009 67 Female 93 lb 1/26/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 3/7/2011 53 Male 2/10/2012 Japan
Primary
Concomitant
Hypogammaglobulinaemia Hospitalization 10/6/2011 69 Male 115 lb 2/13/2012 Physician Japan
Primary
Secondary
Concomitant
Hypertension Hospitalization 1/23/2011 56 Male 126 lb 2/27/2012 Physician Japan
Primary
Secondary
Concomitant

Drug Data