Loxonin combined with Peginterferon Alfa-2B

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 2/2/2010 55 Female 134 lb 6/7/2010 Physician Japan
Primary
Concomitant
Stress Hospitalization 4/7/2010 40 Female 101 lb 6/22/2010 Physician Japan
Primary
Secondary
Concomitant
Vertigo Hospitalization 2/2/2010 55 Female 134 lb 6/25/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 2/2/2010 55 Female 134 lb 7/21/2010 Physician Japan
Primary
Concomitant
Stress Hospitalization 4/7/2010 40 Female 101 lb 8/2/2010 Physician Japan
Primary
Secondary
Concomitant
Stress Hospitalization 4/7/2010 40 Female 101 lb 8/25/2010 Physician Japan
Primary
Secondary
Concomitant
Stress Hospitalization 4/7/2010 40 Female 101 lb 10/21/2010 Physician Japan
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 4/7/2010 40 Female 101 lb 10/29/2010 Physician Japan
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 4/7/2010 40 Female 101 lb 12/16/2010 Physician Japan
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 4/7/2010 40 Female 101 lb 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Erythema Other Serious 2/27/2012 58 Male 3/9/2012 Other Health Professional Japan
Primary
Concomitant
Asthenia Hospitalization 3/2/2012 49 Female 3/16/2012 Japan
Primary
Concomitant
Nausea Other Serious 2/16/2012 62 Female 4/6/2012 Japan
Primary
Concomitant
Pyrexia Other Serious 2/27/2012 58 Male 4/19/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2012 53 Male 4/20/2012 Japan
Primary
Concomitant
Depression Hospitalization 2/27/2012 54 Female 4/20/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Other Serious 2/22/2012 66 Male 4/20/2012 Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/20/2012 36 Female 4/20/2012 Japan
Primary
Concomitant
Malaise Hospitalization 4/9/2012 64 Female 4/20/2012 Japan
Primary
Concomitant
Nausea Other Serious 2/16/2012 54 Female 4/26/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2012 53 Male 4/26/2012 Japan
Primary
Concomitant
Somnolence Hospitalization 2/24/2012 59 Female 5/2/2012 Japan
Primary
Concomitant
Asthenia Hospitalization 3/2/2012 49 Female 5/3/2012 Japan
Primary
Concomitant
Erythema Multiforme Other Serious 2/21/2012 64 Male 5/3/2012 Japan
Primary
Concomitant
Renal Impairment Other Serious 3/26/2012 61 Male 5/7/2012 Other Health Professional Japan
Primary
Concomitant
Renal Impairment 3/26/2012 61 Male 5/8/2012 Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 3/23/2012 38 Male 5/10/2012 Japan
Primary
Concomitant
Depressive Symptom Other Serious 2/3/2012 66 Female 5/14/2012 Japan
Primary
Concomitant
Malaise Hospitalization 3/29/2012 64 Male 5/14/2012 Japan
Primary
Concomitant
Erythema Multiforme Other Serious 3/7/2012 42 Male 5/16/2012 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 4/11/2012 63 Female 5/16/2012 Japan
Primary
Concomitant
Generalised Erythema Hospitalization 4/25/2012 45 Male 5/18/2012 Japan
Primary
Concomitant
Skin Exfoliation Other Serious 5/2/2012 62 Female 5/18/2012 Japan
Primary
Concomitant
Pancytopenia Other Serious 1/24/2012 59 Female 5/23/2012 Japan
Primary
Concomitant
Orthostatic Hypotension Hospitalization 1/20/2012 36 Female 5/24/2012 Other Health Professional Japan
Primary
Concomitant
Hyperuricaemia Hospitalization 2/22/2012 66 Male 5/25/2012 Other Health Professional Japan
Primary
Concomitant
Rash Other Serious 3/17/2012 48 Male 5/25/2012 Other Health Professional Japan
Primary
Concomitant
Dysarthria Other Serious 2/24/2012 59 Female 143 lb 5/21/2012 Physician Japan
Primary
Secondary
Concomitant
Depression Hospitalization 2/27/2012 54 Female 5/29/2012 Other Health Professional Japan
Primary
Concomitant
Renal Disorder Other Serious 2/22/2012 66 Male 5/30/2012 Japan
Primary
Concomitant
Pyrexia Other Serious 4/10/2012 64 Male 152 lb 5/23/2012 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization Female 5/31/2012 Other Health Professional Japan
Primary
Concomitant
Impulsive Behaviour Hospitalization 2/6/2012 64 Female 6/1/2012 Other Health Professional Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 4/17/2012 39 Male 6/1/2012 Japan
Primary
Concomitant
Hypoalbuminaemia Other Serious 2/24/2012 59 Female 6/6/2012 Japan
Primary
Concomitant
Loss Of Consciousness Other Serious 2/16/2012 62 Female 6/6/2012 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 4/11/2012 53 Male 6/6/2012 Japan
Primary
Concomitant
Nausea Other Serious 2/16/2012 54 Female 6/6/2012 Japan
Primary
Concomitant
Erythema Multiforme Other Serious 2/21/2012 64 Male 6/6/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/11/2012 60 Male 6/11/2012 Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 3/31/2012 57 Male 147 lb 5/30/2012 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/24/2012 59 Female 6/14/2012 Japan
Primary
Concomitant
Erythema Multiforme Other Serious 3/7/2012 42 Male 6/20/2012 Japan
Primary
Concomitant
Vomiting Hospitalization 5/25/2012 60 Female 6/20/2012 Other Health Professional Japan
Primary
Concomitant
Small Intestine Ulcer Hospitalization 4/11/2012 60 Male 6/20/2012 Other Health Professional Japan
Primary
Concomitant
Bronchitis Hospitalization 4/20/2012 69 Female 6/21/2012 Other Health Professional Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 3/31/2012 57 Male 147 lb 6/12/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/2/2012 68 Male 6/25/2012 Other Health Professional Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Other Serious 1/20/2012 53 Female 6/26/2012 Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 1/20/2012 53 Female 6/29/2012 Japan
Primary
Concomitant
Erythema Multiforme Hospitalization 5/2/2012 67 Female 6/29/2012 Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/20/2012 36 Female 6/29/2012 Other Health Professional Japan
Primary
Concomitant
Herpes Zoster Other Serious 5/8/2012 65 Female 7/2/2012 Other Health Professional Japan
Primary
Concomitant
Erythema Multiforme Other Serious 4/20/2012 50 Male 7/3/2012 Other Health Professional Japan
Primary
Concomitant
Malaise Hospitalization 3/29/2012 64 Male 7/3/2012 Japan
Primary
Concomitant
Renal Impairment Other Serious 5/9/2012 80 Female 7/5/2012 Japan
Primary
Concomitant
Off Label Use Other Serious 5/1/2012 59 Female 7/11/2012 Other Health Professional Japan
Primary
Concomitant
Vomiting Hospitalization 6/3/2012 61 Female 7/11/2012 Japan
Primary
Concomitant
Depression Other Serious 2/22/2012 66 Male 7/17/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Other Serious 5/1/2012 72 Male 7/19/2012 Other Health Professional Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/17/2012 56 Female 7/20/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/24/2012 59 Female 7/20/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Hospitalization 1/13/2012 54 Female 7/20/2012 Japan
Primary
Concomitant
Anaemia Other Serious 1/13/2012 54 Female 7/23/2012 Japan
Primary
Concomitant
Rash Other Serious 54 Male 7/23/2012 Japan
Primary
Concomitant
Pyelonephritis Hospitalization 5/25/2012 70 Male 7/23/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/20/2012 36 Female 7/24/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2012 53 Male 7/26/2012 Japan
Primary
Concomitant
Anaemia Other Serious 3/2/2012 49 Female 7/30/2012 Japan
Primary
Concomitant
Anaemia Other Serious 1/1/2012 7/31/2012 Physician Japan
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 6/5/2012 58 Male 8/1/2012 Japan
Primary
Concomitant
Drug Eruption Other Serious 4/11/2012 63 Female 8/1/2012 Japan
Primary
Concomitant
Pneumonia Hospitalization 5/2/2012 68 Male 8/3/2012 Other Health Professional Japan
Primary
Concomitant
Haemorrhoids Hospitalization 4/20/2012 67 Male 8/6/2012 Japan
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/20/2012 8/7/2012 Physician Japan
Primary
Secondary
Concomitant
Depression Hospitalization 1/13/2012 8/7/2012 Japan
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 6/5/2012 58 Male 8/8/2012 Japan
Primary
Concomitant
Rash Erythematous Hospitalization 6/5/2012 58 Male 8/9/2012 Japan
Primary
Concomitant
Syncope Hospitalization 7/12/2012 47 Male 8/10/2012 Japan
Primary
Concomitant
Decreased Appetite Hospitalization 7/18/2012 66 Male 8/10/2012 Japan
Primary
Concomitant
Skin Exfoliation Other Serious 5/2/2012 62 Female 8/10/2012 Japan
Primary
Concomitant
Diarrhoea Hospitalization 2/24/2012 59 Female 8/10/2012 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 7/30/2012 47 Male 8/10/2012 Japan
Primary
Concomitant
Renal Impairment Other Serious 6/26/2012 65 Male 8/13/2012 Other Health Professional Japan
Primary
Concomitant
Rash Other Serious 6/25/2012 65 Female 8/13/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Other Serious 5/9/2012 80 Female 8/13/2012 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 5/8/2012 65 Female 8/13/2012 Japan
Primary
Concomitant
Decreased Appetite Hospitalization 4/11/2012 70 Female 8/13/2012 Other Health Professional Japan
Primary
Concomitant
Asthenia Other Serious 3/2/2012 49 Female 8/14/2012 Japan
Primary
Concomitant
Anaemia Other Serious 5/1/2012 8/22/2012 Physician Japan
Primary
Secondary
Concomitant
Heat Illness Death 8/17/2012 8/24/2012 Other Health Professional Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 4/6/2012 8/27/2012 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 1/17/2012 56 Female 12/27/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/13/2012 54 Female 2/27/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Other Serious 3/17/2012 48 Male 12/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 5/25/2012 60 Female 3/14/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Erythema Hospitalization 2/10/2012 54 Male 2/7/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/24/2012 63 Female 104 lb 12/6/2012 Consumer Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/20/2012 36 Female 139 lb 10/16/2012 Consumer Jp
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/13/2012 54 Female 110 lb 3/11/2013 Consumer Jp
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 6/5/2012 58 Male 3/20/2013 Other Health Professional Jp
Primary
Concomitant
Rash Other Serious 6/25/2012 65 Female 3/12/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Anaemia 5/1/2012 12/4/2012 Physician Jp
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 8/10/2012 64 Male 9/13/2012 Other Health Professional Jp
Primary
Concomitant
Nausea Hospitalization 2/16/2012 54 Female 123 lb 11/29/2012 Consumer Jp
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 3/7/2012 9/7/2012 Other Health Professional Jp
Primary
Concomitant
Gastritis Haemorrhagic Other Serious 2/3/2012 66 Female 2/25/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 4/17/2012 9/14/2012 Other Health Professional Jp
Primary
Concomitant
Depression Other Serious 3/21/2012 69 Male 9/17/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinal Haemorrhage Other Serious 9/4/2012 66 Male 3/21/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinopathy Other Serious 7/17/2012 71 Female 3/4/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinitis Other Serious 3/9/2012 62 Female 117 lb 2/20/2013 Consumer Jp
Primary
Secondary
Concomitant
Retinopathy Other Serious 7/26/2012 57 Male 9/20/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Other Serious 7/21/2012 65 Female 9/25/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Off Label Use Hospitalization 3/29/2012 64 Male 11/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Nausea Other Serious 3/17/2012 44 Female 10/4/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/20/2012 36 Female 10/9/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinal Haemorrhage Other Serious 8/14/2012 64 Male 12/19/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Hepatic Cancer Hospitalization 5/1/2012 60 Male 10/17/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 9/6/2012 51 Male 12/3/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Depression Hospitalization 9/10/2012 63 Female 12/26/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 8/16/2012 73 Male 11/16/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Pruritus Hospitalization 8/15/2012 42 Male 10/22/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinal Haemorrhage Other Serious 5/14/2012 69 Male 10/25/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Depression Other Serious 8/28/2012 45 Male 10/29/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 9/14/2012 47 Male 10/30/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Somnolence Other Serious 3/2012 59 Male 141 lb 11/8/2012 Consumer Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/24/2012 59 Female 11/14/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Other Serious 2/10/2012 59 Female 95 lb 11/22/2012 Consumer Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 6/6/2012 57 Female 11/21/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 5/14/2012 65 Male 11/27/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 9/19/2012 62 Male 12/21/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Nausea Hospitalization 4/20/2012 64 Male 11/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 2/21/2012 64 Male 11/29/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/9/2012 66 Male 12/27/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 11/10/2012 62 Female 12/11/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/3/2012 66 Male 12/18/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/19/2012 64 Male 12/27/2012 Other Health Professional Jp
Primary
Concomitant
Neutrophil Count Decreased Other Serious 7/12/2012 67 Male 12/31/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/28/2012 64 Male 10/30/2012 Other Health Professional Jp
Primary
Secondary
Concomitant

Drug Data