Loxonin combined with Oxycontin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinary Retention Hospitalization 11/19/2005 75 Male 116 lb 3/10/2006 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 11/19/2005 75 Male 116 lb 3/24/2006 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 12/28/2005 63 Male 4/17/2006 Physician Japan
Primary
Secondary
Concomitant
Psoriasis 2/6/2006 Male 6/12/2006 Physician Japan
Primary
Concomitant
Ureteral Catheterisation Life Threatening 5/29/2006 57 Male 121 lb 7/13/2006 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Life Threatening 6/1/2006 58 Male 146 lb 7/28/2006 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 5/9/2006 47 Male 172 lb 9/1/2006 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 5/9/2006 47 Male 172 lb 9/5/2006 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 7/16/2006 73 Male 121 lb 9/8/2006 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 5/1/2006 46 Female 99 lb 9/11/2006 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 7/16/2006 73 Male 121 lb 9/14/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 5/9/2006 47 Male 172 lb 9/15/2006 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 5/1/2006 46 Female 99 lb 9/19/2006 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 8/2/2006 Male 150 lb 11/14/2006 Physician Japan
Primary
Secondary
Concomitant
Ureteral Catheterisation Life Threatening 5/29/2006 57 Male 121 lb 11/17/2006 Physician Japan
Primary
Concomitant
Toothache Other Serious 10/21/2006 70 Male 331 lb 12/16/2006 Physician Japan
Primary
Concomitant
Vomiting Other Serious 11/3/2006 69 Male 366 lb 12/19/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Rectal Stenosis Hospitalization 1/11/2007 Male 1/29/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 12/29/2006 Male 88 lb 2/12/2007 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 12/28/2005 63 Male 4/3/2007 Physician Japan
Primary
Secondary
Concomitant
Rectal Stenosis Hospitalization 1/11/2007 Male 4/4/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 12/6/2006 Male 4/19/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Multiple Myeloma Life Threatening 4/4/2004 Male 82 lb 5/3/2007 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 6/26/2007 Consumer Japan
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 7/9/2007 Consumer Japan
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 6/5/2007 63 Male 7/12/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Life Threatening 6/1/2006 58 Male 146 lb 7/12/2007 Physician Japan
Primary
Concomitant
Pneumonitis Hospitalization 6/5/2007 63 Male 7/23/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 6/5/2007 63 Male 7/31/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 6/13/2007 66 Male 108 lb 8/1/2007 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 8/3/2007 Consumer Japan
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 8/9/2007 Consumer Japan
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Other Serious 2/7/2007 72 Male 125 lb 8/7/2007 Physician Japan
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 8/22/2007 Female 146 lb 9/5/2007 Japan
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 8/22/2007 Female 146 lb 9/14/2007 Japan
Primary
Secondary
Concomitant
Protein Total Decreased Hospitalization 8/22/2007 Female 146 lb 9/21/2007 Japan
Primary
Secondary
Concomitant
Cholestasis Life Threatening 8/9/2007 61 Male 9/24/2007
Primary
Secondary
Concomitant
Protein Total Decreased Hospitalization 8/22/2007 Female 146 lb 9/27/2007 Japan
Primary
Secondary
Protein Total Decreased Other Serious Female 9/28/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Cholestasis Life Threatening 8/9/2007 61 Male 10/2/2007
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/23/2007 Male 84 lb 10/1/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/26/2007 68 Female 10/24/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/26/2007 68 Female 10/26/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 10/5/2007 Male 108 lb 10/28/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/26/2005 62 Male 10/29/2007 Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Disability 9/10/2007 65 Female 90 lb 12/3/2007 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 9/26/2007 68 Female 12/4/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/11/2007 71 Male 119 lb 12/4/2007 Other Health Professional United States
Primary
Concomitant
Hyperkalaemia Other Serious 9/3/2007 Male 147 lb 11/27/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 7/24/2007 59 Male 148 lb 12/4/2007 Consumer United States
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 9/3/2007 59 Male 148 lb 12/10/2007 Consumer United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 10/5/2007 Male 108 lb 12/9/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/7/2007 Male 114 lb 12/7/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/24/2007 Female 119 lb 12/9/2007 Physician Japan
Primary
Secondary
Concomitant
Sepsis Death 11/6/2007 Male 12/14/2007 Consumer United Kingdom
Primary
Concomitant
Hyperammonaemia Other Serious 4/9/2004 58 Female 12/18/2007 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 12/25/2006 31 Female 117 lb 12/21/2007 Physician Japan
Primary
Concomitant
Sepsis Death 11/6/2007 Male 12/21/2007 Consumer United Kingdom
Primary
Concomitant
Renal Impairment Life Threatening 2/11/2007 72 Male 1/16/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 2/11/2007 72 Male 1/16/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/22/2007 Male 144 lb 1/21/2008 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 6/7/2007 Female 106 lb 1/24/2008 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 2/7/2007 Male 125 lb 1/17/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 2/11/2007 72 Male 1/25/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/7/2007 72 Male 126 lb 1/28/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/7/2007 Female 106 lb 1/29/2008 Physician Japan
Primary
Concomitant
Renal Impairment Life Threatening 2/7/2007 72 Male 126 lb 1/31/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/7/2007 72 Male 126 lb 2/1/2008 Consumer United States
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 1/30/2008 66 Female 2/7/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/24/2007 Female 119 lb 2/4/2008 Physician Japan
Primary
Secondary
Concomitant
Glossoptosis Other Serious 6/2/2007 86 Male 2/11/2008 Other Health Professional Japan
Primary
Concomitant
Neuropathy Peripheral Hospitalization 2/16/2007 66 Female 2/11/2008 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 1/18/2008 47 Female 106 lb 2/11/2008 Physician Japan
Primary
Secondary
Concomitant
Glossoptosis Other Serious 6/2/2007 86 Male 2/12/2008 Other Health Professional Japan
Primary
Concomitant
Glossoptosis Other Serious 6/2/2007 86 Male 2/14/2008 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 1/16/2008 72 Female 99 lb 2/20/2008 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 5/1/2007 Female 106 lb 2/22/2008 Physician Japan
Primary
Concomitant
Neuropathy Peripheral Hospitalization 2/16/2007 66 Female 2/25/2008 Physician Japan
Primary
Concomitant
Glossoptosis Other Serious 6/2/2007 86 Male 2/27/2008 Other Health Professional Japan
Primary
Concomitant
Glossoptosis Other Serious 6/2/2007 86 Male 2/28/2008 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 1/16/2008 72 Female 99 lb 2/28/2008 Physician Japan
Primary
Concomitant
Neuropathy Peripheral Hospitalization 2/16/2007 66 Female 2/29/2008 Physician Japan
Primary
Concomitant
Pneumonia Death 1/26/2008 Male 2/15/2008 Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/18/2008 47 Female 106 lb 3/10/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/22/2007 Male 144 lb 3/11/2008 Physician Japan
Primary
Concomitant
Rash Hospitalization 1/16/2008 72 Female 99 lb 3/26/2008 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 11/6/2007 Male 3/28/2008 Consumer United Kingdom
Primary
Concomitant
Nausea Death 10/7/2005 49 Female 95 lb 3/31/2008 Physician Japan
Primary
Concomitant
Renal Impairment Life Threatening 2/7/2007 72 Male 126 lb 4/1/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/7/2007 Male 125 lb 3/26/2008 Physician Japan
Primary
Secondary
Concomitant
Metastases To Lung Other Serious 12/13/2007 Female 110 lb 4/21/2008 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 3/2/2008 Female 110 lb 4/22/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2008 Male 142 lb 4/25/2008 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 1/30/2008 62 Female 95 lb 4/28/2008 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 4/1/2008 Male 142 lb 5/1/2008 Physician Japan
Primary
Secondary
Concomitant
Metastases To Peritoneum Other Serious 12/13/2007 Female 110 lb 5/12/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/31/2008 Male 114 lb 5/21/2008 Physician Japan
Primary
Secondary
Concomitant
Metastases To Peritoneum Other Serious 12/13/2007 Female 110 lb 5/30/2008 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 4/1/2008 Male 142 lb 6/5/2008 Physician Japan
Primary
Secondary
Concomitant
Purpura Hospitalization 5/10/2008 Male 155 lb 6/11/2008 Physician United Kingdom
Primary
Concomitant
Stomatitis Hospitalization 9/2/2007 Female 6/20/2008 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 5/31/2008 71 Female 7/1/2008 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 5/31/2008 71 Female 7/9/2008 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Death 6/6/2008 73 Male 141 lb 7/9/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/23/2008 Male 114 lb 7/11/2008 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Death 1/28/2008 63 Female 95 lb 7/24/2008 Physician Japan
Primary
Concomitant
Lung Disorder Death 7/18/2008 70 Male 106 lb 8/5/2008 Other Health Professional Japan
Primary
Concomitant
Sudden Death Death 8/1/2008 62 Female 8/12/2008 Physician Japan
Primary
Concomitant
Tumour Haemorrhage Hospitalization 5/26/2008 28 Male 121 lb 8/25/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/31/2008 Male 164 lb 9/5/2008 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Death 6/6/2008 73 Male 141 lb 9/9/2008 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 7/12/2008 Male 167 lb 9/9/2008 Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 7/29/2008 71 Male 95 lb 9/11/2008 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 8/1/2008 62 Female 115 lb 9/12/2008 Physician Japan
Primary
Concomitant
Metastases To Peritoneum Other Serious 12/13/2007 Female 110 lb 9/16/2008 Physician Japan
Primary
Concomitant
Altered State Of Consciousness Hospitalization 7/12/2008 Male 167 lb 9/24/2008 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/23/2008 Male 114 lb 9/25/2008 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 7/7/2008 53 Male 112 lb 10/9/2008 Other Health Professional Japan
Primary
Concomitant
Platelet Count Decreased Death 6/5/2008 73 Male 141 lb 10/10/2008 Physician Japan
Primary
Concomitant
Urine Output Decreased Other Serious 8/14/2008 Male 104 lb 10/14/2008 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 1/23/2008 Male 104 lb 10/16/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 10/6/2008 61 Male 10/23/2008 Other Health Professional Japan
Primary
Concomitant
Unevaluable Event Other Serious 8/27/2008 Female 10/28/2008 Pharmacist Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/10/2008 Male 162 lb 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 10/6/2008 61 Male 126 lb 11/14/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/12/2008 Male 104 lb 11/17/2008 Pharmacist Japan
Primary
Concomitant
Lung Disorder Hospitalization 5/1/2006 53 Male 112 lb 11/19/2008 Physician Japan
Primary
Concomitant
Pulmonary Haemorrhage Hospitalization 10/6/2008 61 Male 126 lb 11/26/2008 Physician Japan
Primary
Concomitant
Venous Thrombosis Hospitalization 10/3/2008 55 Male 11/20/2008 Physician Japan
Primary
Concomitant
Wound Complication Hospitalization 10/14/2008 Male 11/27/2008 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 3/1/2008 Male 138 lb 11/25/2008 Physician Japan
Primary
Concomitant
Wound Complication Hospitalization 10/14/2008 Male 12/4/2008 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 10/16/2008 59 Male 106 lb 12/5/2008 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 10/31/2008 65 Female 112 lb 12/12/2008 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/10/2008 Male 162 lb 12/16/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/13/2008 62 Male 139 lb 12/29/2008 Physician Japan
Primary
Concomitant
Vena Cava Thrombosis Hospitalization 9/1/2008 Male 151 lb 12/29/2008 Physician Japan
Primary
Concomitant
Metastases To Peritoneum Other Serious 12/13/2007 Female 110 lb 1/21/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 10/30/2008 59 Male 150 lb 2/3/2009 Physician Japan
Primary
Concomitant
Hypertension Life Threatening 11/25/2008 Male 146 lb 2/4/2009 Physician Japan
Primary
Secondary
Concomitant
Thirst Other Serious 10/1/2008 2/5/2009 Physician Japan
Primary
Concomitant
Osteitis Other Serious 3/18/2008 Male 2/5/2009 Physician Japan
Primary
Concomitant
Protein Total Decreased Hospitalization 8/22/2007 2/10/2009 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/29/2008 71 Male 95 lb 2/19/2009 Physician Japan
Primary
Concomitant
Hypercalcaemia Life Threatening 2/18/2009 Female 84 lb 3/13/2009 Physician Japan
Primary
Concomitant
Hypertension Life Threatening 11/25/2008 Male 146 lb 3/17/2009 Physician Japan
Primary
Secondary
Concomitant
Concomitant Disease Aggravated Other Serious 2/18/2009 Female 84 lb 3/26/2009 Physician Japan
Primary
Concomitant
Prostate Cancer Death 1/5/2007 62 Male 3/26/2009 Japan
Primary
Secondary
Concomitant
Prostate Cancer Death 1/5/2007 62 Male 3/27/2009 Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 10/31/2008 65 Female 112 lb 4/9/2009 Physician Germany
Primary
Secondary
Concomitant

Drug Data