Loxonin combined with Oxinorm

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pain In Jaw Other Serious 6/1/2008 Female 8/14/2008 Physician
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 8/14/2008 Male 104 lb 10/14/2008 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Stage Iv Hospitalization 7/15/2008 54 Male 108 lb 10/17/2008 Physician Japan
Primary
Concomitant
Pain In Jaw Other Serious 10/1/2004 Female 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 6/1/2008 Female 11/11/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/12/2008 Male 104 lb 11/17/2008 Pharmacist Japan
Primary
Concomitant
Pain In Jaw Other Serious 6/1/2008 Female 115 lb 11/19/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Iv Life Threatening 11/3/2008 40 Male 181 lb 1/9/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Iv Life Threatening 11/3/2008 40 Male 181 lb 1/12/2009 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 10/30/2008 59 Male 150 lb 2/3/2009 Physician Japan
Primary
Concomitant
Osteitis Other Serious 3/18/2008 Male 2/5/2009 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 12/20/2007 Male 3/9/2009 Physician Japan
Primary
Concomitant
Anorexia Hospitalization 12/4/2008 74 Male 86 lb 3/24/2009 Physician Germany
Primary
Concomitant
Renal Cell Carcinoma Other Serious 11/3/2008 40 Male 181 lb 3/25/2009 Physician Japan
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 12/20/2007 Male 4/6/2009 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Other Serious 11/3/2008 40 Male 181 lb 4/14/2009 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Death 12/20/2007 Male 4/24/2009 Physician Japan
Primary
Concomitant
Pain Other Serious 3/11/2008 Male 6/15/2009 Physician Japan
Primary
Concomitant
Pain Other Serious 3/11/2008 Male 6/26/2009 Physician Japan
Primary
Concomitant
Constipation Hospitalization 3/13/2009 52 Male 7/21/2009 Other Health Professional Japan
Primary
Concomitant
Cystitis Haemorrhagic 3/5/2009 62 Female 110 lb 8/7/2009 Physician Japan
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 6/8/2009 67 Male 112 lb 8/20/2009 Physician Japan
Primary
Concomitant
Off Label Use Death 6/11/2009 Male 112 lb 8/20/2009 Physician Japan
Primary
Concomitant
Lung Adenocarcinoma Hospitalization 6/8/2009 78 Female 95 lb 8/24/2009 Physician Japan
Primary
Concomitant
Pain Other Serious 3/11/2008 Male 9/8/2009 Physician Japan
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 6/8/2009 67 Male 112 lb 9/18/2009 Physician Japan
Primary
Concomitant
Pyrexia Death 1/25/2008 Female 9/21/2009 Physician Japan
Primary
Concomitant
Tracheo-oesophageal Fistula Life Threatening 4/1/2009 Female 93 lb 9/24/2009 Physician Japan
Primary
Concomitant
Off Label Use Death 6/11/2009 Male 112 lb 10/9/2009 Physician Japan
Primary
Concomitant
Swelling Other Serious 7/21/2009 Male 104 lb 10/12/2009 Physician Japan
Primary
Concomitant
Swelling Other Serious 4/30/2009 Male 104 lb 10/14/2009 Physician Japan
Primary
Concomitant
Swelling Other Serious 4/30/2009 Male 104 lb 10/20/2009 Other Health Professional Japan
Primary
Concomitant
Metabolic Encephalopathy Death 6/8/2009 67 Male 112 lb 10/26/2009 Physician Japan
Primary
Concomitant
Lung Disorder Death 7/15/2008 83 Male 123 lb 11/19/2009 Physician Japan
Primary
Concomitant
Metabolic Encephalopathy Death 6/8/2009 67 Male 112 lb 11/30/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/31/2009 75 Male 117 lb 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
Constipation Hospitalization 3/13/2009 52 Male 12/4/2009 Other Health Professional Japan
Primary
Concomitant
Vomiting Other Serious 8/11/2009 Female 90 lb 12/9/2009 Physician Japan
Primary
Concomitant
Venous Thrombosis Other Serious 10/20/2009 71 Female 126 lb 12/16/2009 Physician Germany
Primary
Concomitant
Interstitial Lung Disease Life Threatening 11/18/2009 81 Female 95 lb 12/29/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 11/18/2009 81 Female 95 lb 1/4/2010 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 12/4/2008 74 Male 86 lb 1/14/2010 Physician Germany
Primary
Concomitant
Liver Disorder Other Serious 9/4/2009 66 Male 128 lb 1/15/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 7/29/2009 Female 110 lb 1/28/2010 Physician Japan
Primary
Secondary
Concomitant
Thyroiditis Hospitalization 12/11/2009 74 Male 130 lb 2/1/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 11/18/2009 81 Female 95 lb 2/1/2010 Physician Japan
Primary
Secondary
Concomitant
Off Label Use Death 6/11/2009 Male 112 lb 2/8/2010 Physician Japan
Primary
Concomitant
Yellow Skin Other Serious 8/6/2008 56 Female 99 lb 2/9/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/15/2009 46 Female 2/9/2010 Physician Japan
Primary
Concomitant
Wrong Technique In Drug Usage Process 53 Male 2/12/2010 Pharmacist Japan
Primary
Concomitant
Metabolic Encephalopathy Other Serious 6/8/2009 67 Male 112 lb 2/23/2010 Physician Japan
Primary
Concomitant
Wrong Technique In Drug Usage Process 53 Male 2/26/2010 Pharmacist Japan
Primary
Concomitant
Death Death Female 157 lb 3/2/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/31/2009 75 Male 117 lb 3/3/2010 Physician Japan
Primary
Secondary
Concomitant
Constipation Hospitalization 3/13/2009 52 Male 2/23/2010 Japan
Primary
Concomitant
Pleural Effusion Hospitalization 2/2/2010 63 Male 117 lb 3/4/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 3/13/2009 52 Male 3/4/2010 Other Health Professional Japan
Primary
Concomitant
Urinary Tract Infection Life Threatening 8/5/2009 65 Female 157 lb 3/18/2010 Physician Japan
Primary
Concomitant
Pulmonary Embolism Other Serious 7/29/2009 Female 110 lb 3/18/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 11/3/2008 40 Male 181 lb 4/1/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 73 Male 3/29/2010 Japan
Primary
Concomitant
Vomiting Other Serious 2/21/2010 44 Female 97 lb 4/9/2010 Physician Japan
Primary
Secondary
Concomitant
Protein Urine Life Threatening 2/10/2009 66 Male 150 lb 4/12/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 2/21/2010 44 Female 97 lb 4/12/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 7/15/2008 54 Male 108 lb 4/14/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 11/6/2009 53 Male 4/19/2010 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Life Threatening 3/5/2010 73 Male 4/12/2010 Japan
Primary
Concomitant
Venous Thrombosis Other Serious 10/20/2009 71 Female 126 lb 4/29/2010 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/25/2009 66 Male 119 lb 4/29/2010 Physician Japan
Primary
Concomitant
Ovarian Cancer Death Female 157 lb 4/30/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 8/24/2009 60 Female 5/5/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 2/21/2010 44 Female 97 lb 5/28/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/25/2009 66 Male 119 lb 6/1/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/15/2009 46 Female 112 lb 6/14/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 2/21/2010 44 Female 97 lb 6/15/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 2/21/2010 44 Female 97 lb 6/25/2010 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 4/2/2010 78 Male 110 lb 6/28/2010 Pharmacist Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 4/5/2010 68 Male 132 lb 7/1/2010 Physician Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 3/11/2009 65 Male 7/9/2010 Physician Japan
Primary
Secondary
Concomitant
Metabolic Encephalopathy Other Serious 6/8/2009 67 Male 112 lb 7/16/2010 Other Health Professional Japan
Primary
Concomitant
Dyspnoea Other Serious 3/30/2009 82 Female 154 lb 7/19/2010 Consumer Japan
Primary
Concomitant
Rib Fracture Other Serious 3/30/2009 82 Female 154 lb 7/20/2010 Consumer Japan
Primary
Concomitant
Metabolic Encephalopathy Other Serious 6/8/2009 67 Male 112 lb 7/27/2010 Other Health Professional Japan
Primary
Concomitant
Large Intestine Perforation Hospitalization 6/8/2010 58 Female 130 lb 7/28/2010 Physician Japan
Primary
Secondary
Concomitant
Skin Disorder Other Serious 8/12/2009 79 Male 108 lb 7/28/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 11/6/2009 53 Male 7/30/2010 Physician Japan
Primary
Concomitant
Urine Output Decreased Other Serious 4/2/2010 78 Male 110 lb 7/30/2010 Pharmacist Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 4/5/2010 68 Male 132 lb 8/3/2010 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 6/25/2010 65 Female 8/4/2010 Physician Japan
Primary
Secondary
Concomitant
Nausea Other Serious 4/26/2010 65 Female 86 lb 8/6/2010 Pharmacist Japan
Primary
Concomitant
Renal Tubular Disorder Other Serious 7/15/2010 74 Male 112 lb 8/9/2010 Physician Japan
Primary
Concomitant
Skin Exfoliation Other Serious 5/6/2010 57 Male 179 lb 8/9/2010 Physician Japan
Primary
Concomitant
Pneumonia Bacterial Other Serious 5/14/2009 78 Male 119 lb 8/18/2010 Physician Japan
Primary
Concomitant
Malaise Hospitalization 6/4/2010 65 Female 8/19/2010 Physician Japan
Primary
Secondary
Concomitant
Rib Fracture Other Serious 3/9/2009 82 Female 154 lb 8/20/2010 Consumer Japan
Primary
Concomitant
Renal Disorder Hospitalization 4/27/2010 57 Male 137 lb 8/25/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Other Serious 5/14/2009 78 Male 119 lb 9/6/2010 Physician Japan
Primary
Concomitant
Oesophageal Carcinoma Other Serious 6/22/2010 76 Male 115 lb 9/15/2010 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 6/4/2010 65 Female 9/21/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/29/2008 52 Female 9/27/2010 Physician Japan
Primary
Concomitant
Pulmonary Embolism Other Serious 7/29/2009 62 Female 110 lb 10/6/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 12/11/2009 57 Female 152 lb 10/7/2010 Physician Japan
Primary
Secondary
Concomitant
Off Label Use Death 6/11/2009 78 Male 112 lb 10/7/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 2/21/2010 44 Female 97 lb 10/8/2010 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 6/27/2010 43 Male 181 lb 10/8/2010 Physician Germany
Primary
Concomitant
Multi-organ Failure Hospitalization 10/2/2010 69 Female 125 lb 10/11/2010 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 10/2/2010 69 Female 125 lb 10/12/2010 Physician Japan
Primary
Secondary
Concomitant
Oesophageal Carcinoma Other Serious 6/22/2010 76 Male 115 lb 10/15/2010 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 10/2/2010 69 Female 125 lb 10/20/2010 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 10/2/2010 69 Female 125 lb 10/20/2010 Physician Japan
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 7/29/2010 52 Male 10/21/2010 Physician Japan
Primary
Concomitant
Multi-organ Failure Hospitalization 10/2/2010 69 Female 125 lb 10/21/2010 Physician Japan
Primary
Secondary
Concomitant
Metastases To Central Nervous System Hospitalization 9/15/2010 10/29/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 9/10/2010 11/10/2010 Other Health Professional Japan
Primary
Concomitant
Pancreatic Enzymes Increased Other Serious 4/13/2010 64 Male 139 lb 11/17/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 10/20/2010 11/17/2010 Other Health Professional Japan
Primary
Concomitant
Radiation Pneumonitis Other Serious 8/6/2010 62 Male 11/17/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 7/1/2010 45 Male 132 lb 11/17/2010 Physician Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 9/15/2010 11/30/2010 Physician Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 9/15/2010 11/30/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 10/20/2010 11/30/2010 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 9/11/2010 60 Female 95 lb 12/13/2010 Physician Japan
Primary
Concomitant
Radiation Pneumonitis Other Serious 8/6/2010 62 Male 12/13/2010 Physician Japan
Primary
Concomitant
Subileus Hospitalization 7/2/2010 12/20/2010 Physician Japan
Primary
Concomitant
Pulmonary Oedema Life Threatening 10/20/2010 12/20/2010 Japan
Primary
Concomitant
Radiation Oesophagitis Hospitalization 7/1/2009 35 Female 95 lb 12/23/2010 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 10/16/2010 67 Male 141 lb 12/23/2010 Physician Japan
Primary
Concomitant
Neuropathy Peripheral Hospitalization 9/8/2010 12/23/2010 Physician Japan
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 5/6/2010 57 Male 179 lb 12/29/2010 Physician Japan
Primary
Concomitant
Cardio-respiratory Arrest Life Threatening 12/14/2010 62 Male 132 lb 12/30/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/9/2010 12/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Apallic Syndrome Life Threatening 12/14/2010 62 Male 132 lb 1/5/2011 Consumer Japan
Primary
Concomitant
Renal Failure Chronic Hospitalization 12/11/2009 57 Female 152 lb 1/5/2011 Physician Japan
Primary
Secondary
Concomitant
Paronychia Hospitalization 7/7/2010 1/5/2011 Physician Japan
Primary
Secondary
Concomitant
Apallic Syndrome Disability 12/14/2010 62 Male 132 lb 1/6/2011 Consumer Japan
Primary
Concomitant
Vomiting Hospitalization 9/10/2010 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Death 10/18/2008 46 Female 112 lb 1/17/2011 Physician Japan
Primary
Concomitant
Sensory Disturbance Other Serious 10/18/2008 46 Female 112 lb 1/26/2011 Physician Japan
Primary
Concomitant
Anaemia Other Serious 10/18/2008 46 Female 112 lb 1/27/2011 Physician Japan
Primary
Concomitant
Decreased Appetite Death 12/11/2010 47 Male 148 lb 1/28/2011 Physician Japan
Primary
Concomitant
Subileus Hospitalization 7/2/2010 60 Female 119 lb 2/4/2011 Physician Japan
Primary
Concomitant
Acne Hospitalization 8/9/2010 66 Female 90 lb 2/4/2011 Physician Japan
Primary
Concomitant
Paronychia Hospitalization 7/7/2010 76 Male 170 lb 2/8/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Death 12/17/2009 60 Male 110 lb 2/28/2011 Physician Japan
Primary
Secondary
Concomitant
Depression Hospitalization 11/6/2009 52 Male 3/1/2011 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 11/6/2009 52 Male 3/1/2011 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 2/2/2011 66 Female 3/4/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 10/29/2010 47 Female 93 lb 3/4/2011 Physician Japan
Primary
Concomitant
Diarrhoea Death 1/26/2011 63 Male 116 lb 3/4/2011 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/19/2010 76 Male 119 lb 3/8/2011 Physician Japan
Primary
Concomitant

Drug Data