Loxonin combined with Methycobal

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hallucination Hospitalization 6/19/2007 55 Female 101 lb 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 3/25/2007 70 Female 8/7/2007 Physician Japan
Primary
Concomitant
Dementia Other Serious 7/19/2007 73 Female 8/7/2007 Pharmacist Japan
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 68 Female 8/10/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 7/26/2007 Male 8/10/2007 Physician Japan
Primary
Concomitant
Lymphocyte Count Decreased Other Serious 2/7/2007 72 Male 125 lb 8/7/2007 Physician Japan
Primary
Secondary
Concomitant
Restlessness Disability 7/31/2007 83 Female 8/21/2007 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 68 Female 8/22/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/22/2007 68 Female 9/4/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Dementia Other Serious 7/22/2007 73 Female 9/5/2007 Pharmacist Japan
Primary
Concomitant
Vomiting Hospitalization 8/20/2007 61 Female 121 lb 9/27/2007 Physician Japan
Primary
Secondary
Concomitant
Restlessness Hospitalization 6/19/2007 55 Female 101 lb 10/11/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 10/2/2007 63 Female 10/26/2007 Pharmacist Japan
Primary
Concomitant
Renal Failure Acute Death 7/10/2007 52 Female 10/29/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/2/2007 63 Female 146 lb 10/31/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/2/2007 63 Female 146 lb 11/7/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Renal Function Test Abnormal Life Threatening 9/11/2007 72 Male 11/8/2007 Pharmacist Japan
Primary
Concomitant
Vomiting Life Threatening 10/2/2007 63 Female 146 lb 11/14/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Respiratory Disorder Life Threatening 4/9/2009 74 Male 139 lb 8/31/2009 Physician Japan
Primary
Concomitant
Nausea Hospitalization 3/31/2009 74 Male 9/2/2009 Other Health Professional Japan
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 2/15/2007 51 Female 9/11/2009 Other Health Professional Japan
Primary
Concomitant
Toxic Encephalopathy Hospitalization 7/21/2009 Male 9/11/2009 Pharmacist Japan
Primary
Concomitant
Toxic Encephalopathy Hospitalization 7/21/2009 Male 10/7/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Pyelonephritis Acute Hospitalization 9/25/2009 58 Female 108 lb 10/2/2009 Physician Japan
Primary
Concomitant
Off Label Use Death 6/11/2009 Male 112 lb 10/9/2009 Physician Japan
Primary
Concomitant
Organising Pneumonia Hospitalization Female 84 lb 10/9/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 81 Female 84 lb 10/9/2009 Physician Japan
Primary
Concomitant
Pyelonephritis Acute Hospitalization 9/25/2009 58 Female 108 lb 10/8/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 1/1/2009 Female 10/21/2009 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 4/6/2009 72 10/27/2009 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 1/1/2009 Female 153 lb 11/5/2009 Physician Japan
Primary
Secondary
Concomitant
Organising Pneumonia Hospitalization Female 84 lb 11/16/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/18/2009 Female 11/19/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 1/1/2009 Female 11/23/2009 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 3/31/2009 74 Male 11/25/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/28/2007 Male 127 lb 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/7/2007 Male 114 lb 11/30/2009 Physician Japan
Primary
Concomitant
Palpitations Hospitalization 10/17/2007 Male 152 lb 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/5/2007 Male 143 lb 12/1/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/10/2008 Male 162 lb 12/1/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/25/2007 Male 154 lb 12/1/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 8/11/2009 Female 90 lb 12/9/2009 Physician Japan
Primary
Concomitant
Hepatitis Other Serious 12/11/2008 68 Female 12/14/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/1/2009 Female 12/15/2009 Physician Japan
Primary
Secondary
Concomitant
Intestinal Fistula Disability 8/24/2009 Female 115 lb 12/16/2009 Physician Japan
Primary
Concomitant
Nausea Hospitalization 3/31/2009 74 Male 12/15/2009 Japan
Primary
Concomitant
Sciatica Hospitalization 7/18/2009 76 Female 107 lb 12/21/2009 Physician Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 1/1/2009 Male 168 lb 12/22/2009 Other Health Professional Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 3/6/2009 Male 229 lb 12/23/2009 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 6/18/2009 58 Female 128 lb 12/30/2009 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 12/5/2009 75 Male 143 lb 1/12/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/3/2009 Female 121 lb 1/19/2010 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Disability 8/2/2008 57 Female 143 lb 1/27/2010 Physician Japan
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/7/2010 54 Female 1/29/2010 Japan
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/7/2010 64 Female 2/3/2010 Japan
Primary
Concomitant
Renal Impairment Other Serious 12/5/2009 75 Male 143 lb 2/3/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 3/18/2009 Female 105 lb 2/5/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 4/30/2009 Male 116 lb 2/8/2010 Physician Japan
Primary
Concomitant
Off Label Use Death 6/11/2009 Male 112 lb 2/8/2010 Physician Japan
Primary
Concomitant
Altered State Of Consciousness Hospitalization 1/23/2010 Female 112 lb 2/12/2010 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Death 12/4/2009 Female 93 lb 2/12/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 3/16/2008 Female 123 lb 2/22/2010 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 6/1/2007 73 Female 99 lb 2/22/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Life Threatening 12/20/2009 Female 110 lb 2/23/2010 Physician Japan
Primary
Concomitant
Malaise Hospitalization 8/3/2009 Female 121 lb 2/25/2010 Physician Japan
Primary
Concomitant
Knee Arthroplasty Hospitalization 11/25/2008 Female 119 lb 2/25/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Disorder Life Threatening 4/9/2009 74 Male 139 lb 3/1/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 6/18/2009 58 Female 128 lb 3/4/2010 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 2/4/2010 70 Female 143 lb 3/4/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/11/2010 55 Female 134 lb 3/4/2010 Physician Japan
Primary
Concomitant
Nausea Hospitalization 3/31/2009 74 Male 3/4/2010 Other Health Professional Japan
Primary
Concomitant
Femur Fracture Other Serious 3/1/2010 62 Female 3/22/2010 Physician Japan
Primary
Secondary
Concomitant
Knee Arthroplasty Hospitalization 11/25/2008 Female 119 lb 3/22/2010 Physician Japan
Primary
Secondary
Concomitant
Altered State Of Consciousness Hospitalization 1/23/2010 Female 112 lb 3/24/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Life Threatening 12/20/2009 Female 110 lb 3/26/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/28/2009 Female 3/30/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/2/2010 55 Female 134 lb 3/25/2010 Physician Japan
Primary
Concomitant
Glomerulonephritis Acute Other Serious 3/16/2010 61 Female 126 lb 4/6/2010 Physician Japan
Primary
Concomitant
Haematochezia Other Serious 3/26/2010 32 Male 4/7/2010 Pharmacist Japan
Primary
Concomitant
Hand Fracture Disability 3/24/2009 62 Female 4/7/2010 Physician Japan
Primary
Secondary
Concomitant
Haematochezia Other Serious 3/26/2010 32 Male 4/15/2010 Pharmacist Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 11/6/2009 53 Male 4/19/2010 Physician Japan
Primary
Concomitant
Rash Death 8/19/2009 57 Male 141 lb 4/20/2010 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 6/1/2007 73 Female 99 lb 4/20/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/28/2009 75 Female 4/23/2010 Physician Japan
Primary
Secondary
Concomitant
Female Genital Tract Fistula Disability 8/24/2009 57 Female 115 lb 4/26/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Disability 9/15/2009 58 Male 115 lb 4/26/2010 Physician Japan
Primary
Concomitant
Splenomegaly Other Serious 2/12/2010 64 Female 4/27/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 12/4/2009 76 Female 93 lb 4/27/2010 Physician Japan
Primary
Concomitant
Hand Fracture Hospitalization 3/24/2009 61 Female 5/3/2010 Physician Japan
Primary
Secondary
Concomitant
Altered State Of Consciousness Hospitalization 1/23/2010 76 Female 112 lb 5/3/2010 Physician Japan
Primary
Concomitant
Vertigo Hospitalization 2/2/2010 55 Female 134 lb 6/25/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 68 Female 7/1/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Pulmonary Thrombosis Hospitalization 11/9/2009 49 Male 151 lb 6/30/2010 Physician Japan
Primary
Concomitant
Lymphopenia Other Serious 6/1/2009 71 Male 139 lb 7/9/2010 Physician Japan
Primary
Concomitant
Viith Nerve Paralysis Disability 8/1/2009 62 Male 7/15/2010 Consumer Switzerland
Primary
Concomitant
Platelet Count Decreased Hospitalization 2/12/2010 80 Male 121 lb 7/16/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 12/9/2008 59 Female 73 lb 7/23/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 2/2/2010 55 Female 134 lb 7/21/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 6/27/2009 73 Female 115 lb 7/26/2010 Physician Japan
Primary
Concomitant
Osteomyelitis Other Serious 5/27/2010 88 Female 7/30/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 11/6/2009 53 Male 7/30/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 1/24/2010 76 Female 112 lb 7/30/2010 Physician Japan
Primary
Concomitant
Partial Seizures Other Serious 7/15/2010 79 Male 8/2/2010 Physician Japan
Primary
Concomitant
Staphylococcal Infection Life Threatening 4/5/2010 55 Male 123 lb 8/3/2010 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 11/30/2009 63 Male 110 lb 8/4/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/27/2010 70 Female 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Pain Other Serious 7/15/2010 79 Male 108 lb 8/13/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 6/14/2010 78 Male 101 lb 8/16/2010 Japan
Primary
Concomitant
Staphylococcal Infection Life Threatening 4/5/2010 55 Male 123 lb 8/23/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Disorder Life Threatening 4/9/2009 74 Male 139 lb 8/24/2010 Physician Japan
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 6/23/2010 65 Female 123 lb 8/25/2010 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 7/16/2010 69 Female 99 lb 8/25/2010 Physician Japan
Primary
Concomitant
Interacting
Hepatic Neoplasm Malignant Death 5/28/2010 80 Male 99 lb 8/26/2010 Physician Japan
Primary
Concomitant
Pain Other Serious 7/15/2010 79 Male 108 lb 8/27/2010 Physician Japan
Primary
Secondary
Hepatic Function Abnormal Other Serious 7/20/2010 65 Male 128 lb 8/27/2010 Physician Japan
Primary
Concomitant
Tumour Haemorrhage Life Threatening 11/30/2009 63 Male 110 lb 8/30/2010 Physician Japan
Primary
Concomitant
Agranulocytosis Hospitalization 7/15/2010 45 Female 9/1/2010 Physician Japan
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 7/21/2009 65 Male 132 lb 9/1/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 1/18/2010 61 Female 112 lb 9/1/2010 Physician Japan
Primary
Secondary
Concomitant
Pain Other Serious 7/15/2010 79 Male 108 lb 9/3/2010 Physician Japan
Primary
Secondary
C-reactive Protein Increased Hospitalization 1/12/2010 73 Male 117 lb 9/6/2010 Physician Japan
Primary
Concomitant
Agranulocytosis Hospitalization 7/15/2010 45 Female 9/7/2010 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 8/7/2010 62 Male 108 lb 9/13/2010 Physician Japan
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 12/3/2004 58 Male 9/17/2010 Japan
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 12/3/2004 58 Male 9/17/2010 Japan
Primary
Concomitant
Pneumothorax Hospitalization 11/7/2007 69 Male 9/23/2010 Consumer Japan
Primary
Secondary
Concomitant
Glomerulonephritis Acute Other Serious 3/16/2010 61 Female 126 lb 9/23/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 6/14/2010 78 Male 101 lb 9/23/2010 Pharmacist Japan
Primary
Concomitant
Pneumothorax Hospitalization 11/7/2007 69 Male 9/27/2010 Consumer Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 9/1/2010 64 Male 9/30/2010 Physician Japan
Primary
Concomitant
Off Label Use Death 6/11/2009 78 Male 112 lb 10/7/2010 Physician Japan
Primary
Concomitant
Sputum Culture Positive Death 4/30/2009 71 Male 116 lb 10/7/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 8/3/2009 69 Female 121 lb 10/8/2010 Physician Japan
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 9/8/2010 70 Male 10/10/2010 Pharmacist Japan
Primary
Concomitant
Postoperative Wound Infection Other Serious 5/18/2010 68 Female 143 lb 10/12/2010 Physician Japan
Primary
Concomitant
Viith Nerve Paralysis Disability 8/1/2009 62 Male 10/14/2010 Consumer Switzerland
Primary
Concomitant
Platelet Count Decreased Hospitalization 2/12/2010 80 Male 121 lb 10/13/2010 Physician Japan
Primary
Concomitant
Postoperative Wound Infection Other Serious 5/18/2010 68 Female 143 lb 10/15/2010 Physician Japan
Primary
Concomitant
Myocardial Infarction Hospitalization 4/13/2010 45 Female 139 lb 10/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/1/2010 77 Female 12/10/2010 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/3/2009 60 Female 121 lb 12/13/2010 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 10/12/2010 73 Female 94 lb 12/14/2010 Physician Japan
Primary
Secondary
Concomitant
Cataract Hospitalization 9/25/2009 57 Female 104 lb 12/15/2010 Japan
Primary
Concomitant
Tension Headache Other Serious 10/6/2009 30 Female 12/17/2010 Physician Japan
Primary
Concomitant
Cardiac Failure Acute Other Serious 11/30/2010 60 Male 101 lb 12/21/2010 Physician Japan
Primary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 1/1/1999 76 Female 128 lb 12/23/2010 Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 10/25/2010 67 Female 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Lymphopenia Hospitalization 2/4/2009 71 Male 137 lb 12/28/2010 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 4/30/2009 83 Female 97 lb 12/29/2010 Physician Japan
Primary
Concomitant

Drug Data