Loxonin combined with Magnesium Oxide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Hospitalization 9/8/2005 47 Male 128 lb 1/5/2006 Physician Japan
Primary
Concomitant
Vomiting Other Serious 10/27/2005 74 Female 1/6/2006 Other Health Professional France
Primary
Concomitant
Drug Interaction Other Serious 6/14/2005 Female 95 lb 1/18/2006 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 1/4/2006 70 Male 1/18/2006 Physician Japan
Primary
Concomitant
Red Blood Cell Count Decreased Life Threatening 6/1/2004 56 Female 144 lb 1/30/2006 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/1/2005 82 Female 82 lb 2/9/2006 Physician Japan
Primary
Concomitant
Cough Other Serious 11/22/2005 29 Female 86 lb 2/9/2006 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 1/4/2006 69 Male 96 lb 2/23/2006 Physician Japan
Primary
Concomitant
Cardiomegaly Other Serious 11/15/2005 Female 2/23/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/1/2005 82 Female 82 lb 2/24/2006 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Death 6/1/2004 56 Female 144 lb 3/6/2006 Physician Japan
Primary
Secondary
Concomitant
Cardiomegaly Other Serious 11/15/2005 Female 3/7/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/27/2005 74 Female 3/15/2006 Other Health Professional France
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2005 82 Female 82 lb 3/23/2006 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 11/28/2005 70 Male 3/16/2006 Physician Japan
Primary
Secondary
Concomitant
Cough Other Serious 11/22/2005 29 Female 86 lb 3/15/2006 Physician Japan
Primary
Secondary
Concomitant
Parkinsonism Disability 9/1/2005 76 Female 4/7/2006 Physician Japan
Primary
Concomitant
Breast Cancer Other Serious 6/14/2005 Female 95 lb 4/11/2006 Physician Japan
Primary
Concomitant
Rash Other Serious 11/28/2005 70 Male 5/24/2006 Physician Japan
Primary
Secondary
Concomitant
Lymphocyte Stimulation Test Positive Hospitalization 5/1/2006 77 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
Laboratory Test Abnormal Hospitalization 8/29/2003 65 Female 99 lb 7/17/2006 Physician Japan
Primary
Concomitant
Neutropenia Hospitalization 6/9/2006 68 Male 7/17/2006 Physician France
Primary
Concomitant
Lymphocyte Stimulation Test Positive Hospitalization 5/1/2006 77 Male 9/5/2006 Physician Japan
Primary
Secondary
Concomitant
Ovarian Cyst Ruptured Other Serious 11/29/2005 58 Female 99 lb 9/25/2006 Consumer Germany
Primary
Secondary
Concomitant
Fatigue Hospitalization 10/24/2006 67 Male 137 lb 11/6/2006 Physician Japan
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 10/24/2006 67 Male 137 lb 11/14/2006 Physician Japan
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 10/24/2006 67 Male 137 lb 11/20/2006 Physician Japan
Primary
Secondary
Concomitant
Lymphangiosis Carcinomatosa Life Threatening 9/21/2006 68 Male 132 lb 12/19/2006 Physician Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 1/2/2007 66 Male 1/29/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Rectal Stenosis Hospitalization 1/11/2007 Male 1/29/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Septic Shock Other Serious 11/28/2006 57 Female 88 lb 1/27/2007 Physician Japan
Primary
Concomitant
Loss Of Consciousness Other Serious 1/20/2007 89 Female 1/31/2007 Physician Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 66 Male 2/9/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 1/20/2007 Female 2/13/2007 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 11/28/2006 57 Female 88 lb 2/7/2007 Physician Japan
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/22/2007 86 Female 3/2/2007 Physician Japan
Primary
Concomitant
Muscular Weakness Hospitalization 2/25/2007 71 Male 130 lb 3/12/2007 Physician Japan
Primary
Concomitant
Muscular Weakness Hospitalization 2/25/2007 71 Male 130 lb 3/20/2007 Physician Japan
Primary
Concomitant
Rectal Stenosis Hospitalization 1/11/2007 Male 4/4/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 4/12/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Laryngeal Oedema Hospitalization 5/1/2006 77 Male 4/20/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/6/2007 68 Female 4/11/2007
Primary
Concomitant
Muscular Weakness Hospitalization 2/25/2007 71 Male 130 lb 5/2/2007 Physician Japan
Primary
Concomitant
Delirium Other Serious 3/27/2007 76 Male 5/21/2007 Pharmacist Japan
Primary
Concomitant
Wound Infection Hospitalization 10/23/2006 52 Male 143 lb 5/29/2007 Physician Japan
Primary
Concomitant
Blood Creatinine Increased Hospitalization 5/22/2007 Male 6/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/22/2007 Male 6/11/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Eruption Hospitalization 5/3/2007 72 Male 6/14/2007 Physician Japan
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/22/2007 86 Female 6/25/2007 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/13/2007 68 Female 6/29/2007 Physician Japan
Primary
Secondary
Concomitant
Shock Death 4/18/2007 71 Female 102 lb 7/9/2007 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/13/2007 68 Female 141 lb 7/13/2007 Physician Japan
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 7/6/2007 75 Female 7/19/2007 Physician Japan
Primary
Concomitant
Hypoglycaemic Coma Life Threatening 7/7/2007 78 Female 7/20/2007 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/13/2007 68 Female 141 lb 7/23/2007 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemic Coma Life Threatening 7/7/2007 78 Female 7/24/2007 Physician Japan
Primary
Concomitant
Hypoglycaemic Coma Life Threatening 7/7/2007 78 Female 115 lb 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 52 Male 8/7/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 Male 8/10/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Myalgia Other Serious 3/13/2007 52 Male 8/14/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 Male 8/16/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Disability 6/13/2006 Female 8/16/2007 Physician Japan
Primary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 52 Male 8/21/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 Male 8/22/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Mitral Valve Incompetence Other Serious 7/6/2007 75 Female 9/1/2007 Physician Japan
Primary
Concomitant
Urticaria Hospitalization 2/25/2007 Female 9/12/2007 Physician Japan
Primary
Secondary
Concomitant
Cholestasis Life Threatening 8/9/2007 61 Male 9/24/2007
Primary
Secondary
Concomitant
Cholestasis Life Threatening 8/9/2007 61 Male 10/2/2007
Primary
Secondary
Concomitant
Post Procedural Infection Hospitalization 10/23/2006 52 Male 143 lb 9/28/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 9/24/2007 73 Male 150 lb 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Subdural Haematoma Evacuation Other Serious 1/6/2007 61 Male 146 lb 11/1/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 9/24/2007 73 Male 150 lb 11/6/2007 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 9/9/2007 Female 11/6/2007 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 9/9/2007 Female 11/12/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/27/2007 Female 150 lb 11/16/2007 Physician Japan
Primary
Concomitant
Subdural Haematoma Evacuation Other Serious 1/6/2007 61 Male 146 lb 11/19/2007 Physician Japan
Primary
Concomitant
Sepsis Death 8/23/2007 Male 132 lb 11/21/2007 Physician Japan
Primary
Concomitant
Dermatitis Acneiform Disability 9/10/2007 65 Female 90 lb 12/3/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 5/22/2007 Male 12/13/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Septic Shock Other Serious 12/25/2006 31 Female 117 lb 12/21/2007 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 2/13/2006 Male 50 lb 12/21/2007 Physician Japan
Primary
Concomitant
Subdural Haematoma Evacuation Other Serious 1/6/2007 61 Male 146 lb 12/25/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/1/2007 50 Female 79 lb 12/28/2007 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 12/18/2007 Male 1/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/27/2007 Female 150 lb 1/15/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/11/2007 76 Female 1/18/2008 Physician Japan
Primary
Secondary
Concomitant
Pyoderma Gangrenosum Hospitalization 11/1/2007 Female 121 lb 1/22/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 9/27/2007 Female 150 lb 1/25/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/11/2007 76 Female 112 lb 1/26/2008 Physician Japan
Primary
Secondary
Concomitant
Glossoptosis Other Serious 6/2/2007 86 Male 2/11/2008 Other Health Professional Japan
Primary
Concomitant
Pyoderma Gangrenosum Hospitalization 11/1/2007 Female 121 lb 2/11/2008 Physician Japan
Primary
Concomitant
Glossoptosis Other Serious 6/2/2007 86 Male 2/12/2008 Other Health Professional Japan
Primary
Concomitant
Glossoptosis Other Serious 6/2/2007 86 Male 2/14/2008 Other Health Professional Japan
Primary
Concomitant
Splenomegaly Life Threatening 9/26/2007 Female 2/15/2008 Physician Japan
Primary
Concomitant
Glossoptosis Other Serious 6/2/2007 86 Male 2/27/2008 Other Health Professional Japan
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 1/19/2008 80 Male 121 lb 2/28/2008 Physician Japan
Primary
Concomitant
Glossoptosis Other Serious 6/2/2007 86 Male 2/28/2008 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/1/2007 50 Female 79 lb 2/29/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/1/2007 50 Female 79 lb 3/4/2008 Physician Japan
Primary
Secondary
Concomitant
Infusion Related Reaction Life Threatening 9/26/2007 Female 3/5/2008 Physician Japan
Primary
Concomitant
Somnolence Life Threatening 11/5/2007 Male 123 lb 3/11/2008 Pharmacist Japan
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 1/19/2008 80 Male 121 lb 3/19/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 3/6/2008 80 Female 110 lb 3/27/2008 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 12/11/2007 Male 4/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious 2/29/2008 Female 4/14/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 3/6/2008 80 Female 110 lb 4/16/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 3/6/2008 80 Female 110 lb 4/17/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 3/6/2008 80 Female 110 lb 4/24/2008 Physician Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 2/26/2008 Female 4/24/2008 Pharmacist Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2008 Male 142 lb 4/25/2008 Physician Japan
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 2/26/2008 Female 4/30/2008 Physician Japan
Primary
Secondary
Concomitant
Cataract Hospitalization 4/25/2008 69 Female 5/2/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 4/1/2008 Male 142 lb 5/1/2008 Physician Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 2/29/2008 Female 5/12/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 3/6/2008 80 Female 110 lb 5/16/2008 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 4/25/2008 Female 85 lb 5/30/2008 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 4/25/2008 Female 85 lb 6/9/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 4/1/2008 Male 142 lb 6/5/2008 Physician Japan
Primary
Secondary
Concomitant
Cataract Hospitalization 4/25/2008 69 Female 6/17/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Large Intestine Carcinoma Life Threatening 3/6/2008 Female 6/13/2008 Physician Japan
Primary
Concomitant
Vertebral Artery Occlusion Hospitalization 5/28/2008 Female 86 lb 6/18/2008 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 6/3/2008 77 Male 146 lb 6/20/2008 Physician Japan
Primary
Concomitant
Gastrointestinal Perforation Death 6/14/2008 64 Female 6/20/2008 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Death 6/14/2008 74 Female 6/24/2008 Physician Japan
Primary
Secondary
Concomitant
Flatulence Other Serious 75 Female 6/25/2008 Pharmacist Japan
Primary
Secondary
White Blood Cell Count Decreased Disability 5/29/2007 74 Female 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Flatulence Other Serious 75 Female 7/2/2008 Pharmacist Japan
Primary
Secondary
Therapeutic Response Decreased Other Serious 12/7/2006 42 Female 7/3/2008 Physician Japan
Primary
Concomitant
Vertebral Artery Occlusion Hospitalization 5/28/2008 Female 86 lb 7/14/2008 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 12/7/2006 42 Female 7/18/2008 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 12/7/2006 42 Female 7/23/2008 Physician Japan
Primary
Concomitant
Large Intestine Carcinoma Death 3/6/2008 Female 7/22/2008 Physician Japan
Primary
Concomitant
Neutropenia Hospitalization 7/18/2008 77 Female 7/29/2008 Pharmacist Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 12/28/2007 42 Female 8/5/2008 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 7/31/2008 Male 139 lb 8/12/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 7/9/2008 Female 108 lb 9/12/2008 Japan
Primary
Concomitant
Cardiac Failure Other Serious 7/31/2008 Male 139 lb 9/16/2008 Physician Japan
Primary
Secondary
Concomitant
Nephrotic Syndrome Hospitalization 6/28/2006 Female 101 lb 10/6/2008 Physician Japan
Primary
Concomitant
Respiratory Disorder Life Threatening 9/4/2008 Female 101 lb 10/10/2008 Physician Japan
Primary
Concomitant
Lymphopenia Hospitalization 8/26/2004 36 Female 10/15/2008 Japan
Primary
Concomitant
Urine Output Decreased Other Serious 8/14/2008 Male 104 lb 10/14/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 8/13/2008 Female 141 lb 10/20/2008 Physician Japan
Primary
Concomitant
Sudden Hearing Loss Hospitalization 10/15/2008 Female 97 lb 10/29/2008 Other Health Professional Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 10/19/2008 Female 125 lb 10/31/2008 Japan
Primary
Concomitant
Sudden Hearing Loss Hospitalization 10/15/2008 Female 97 lb 11/7/2008 Other Health Professional Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 10/19/2008 Female 125 lb 11/11/2008 Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/12/2008 Male 104 lb 11/17/2008 Pharmacist Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 8/1/2008 78 Male 123 lb 11/18/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 8/13/2008 Female 134 lb 11/20/2008 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 10/19/2008 Female 125 lb 11/20/2008 Japan
Primary
Concomitant

Drug Data