Loxonin combined with Lyrica

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lung Neoplasm Malignant Death 81 Female 7/16/2010 Physician Japan
Primary
Concomitant
Lung Neoplasm Malignant Death 81 Female 7/23/2010 Physician Japan
Primary
Concomitant
Partial Seizures Other Serious 7/15/2010 79 Male 8/2/2010 Physician Japan
Primary
Concomitant
Atrial Fibrillation Other Serious 88 Male 8/10/2010 Physician Japan
Primary
Concomitant
Hyperkalaemia Other Serious 7/28/2010 87 Female 8/11/2010 Physician Japan
Primary
Concomitant
Pain Other Serious 7/15/2010 79 Male 108 lb 8/13/2010 Physician Japan
Primary
Concomitant
Wheezing Hospitalization 7/20/2010 83 Female 8/13/2010 Physician Japan
Primary
Concomitant
Liver Function Test Abnormal Other Serious 6/24/2010 80 Male 8/20/2010 Physician Japan
Primary
Concomitant
Chest Discomfort Other Serious 7/7/2010 88 Female 154 lb 8/24/2010 Physician Japan
Primary
Concomitant
Oedema Peripheral Other Serious 7/16/2010 69 Female 99 lb 8/25/2010 Physician Japan
Primary
Concomitant
Interacting
Pain Other Serious 7/15/2010 79 Male 108 lb 8/27/2010 Physician Japan
Primary
Secondary
Death Death 8/19/2010 80 Male 8/31/2010 Physician Japan
Primary
Concomitant
Pain Other Serious 7/15/2010 79 Male 108 lb 9/3/2010 Physician Japan
Primary
Secondary
Weight Increased Other Serious 8/12/2010 79 Female 132 lb 9/15/2010 Physician Japan
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death 81 Female 9/16/2010 Physician Japan
Primary
Concomitant
Chest Discomfort Other Serious 7/7/2010 88 Female 154 lb 9/16/2010 Physician Japan
Primary
Concomitant
Loss Of Consciousness Other Serious 1/1/2010 90 Female 9/17/2010 Physician Japan
Primary
Concomitant
Hyperkalaemia Other Serious 7/21/2010 87 Female 9/21/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/12/2010 79 Female 132 lb 10/8/2010 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 8/27/2010 82 Female 10/7/2010 Physician Japan
Primary
Concomitant
Hyperkalaemia Other Serious 7/21/2010 87 Female 10/7/2010 Physician Japan
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Other Serious 9/8/2010 70 Male 10/10/2010 Pharmacist Japan
Primary
Concomitant
Visual Impairment Other Serious 7/1/2010 76 Male 104 lb 10/18/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 8/7/2010 96 Female 123 lb 10/19/2010 Physician Japan
Primary
Concomitant
Death Death 8/19/2010 80 Male 10/21/2010 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 9/28/2010 73 Female 110 lb 10/26/2010 Pharmacist Japan
Primary
Concomitant
Somnolence Other Serious 8/7/2010 96 Female 123 lb 11/3/2010 Physician Japan
Primary
Concomitant
Somnolence Hospitalization 9/29/2010 75 Male 11/5/2010 Pharmacist Japan
Primary
Concomitant
Speech Disorder Other Serious 9/1/2010 87 Female 11/5/2010 Physician Japan
Primary
Concomitant
Dizziness Other Serious 10/29/2009 76 Female 11/9/2010 Pharmacist Japan
Primary
Concomitant
Hypoaesthesia Oral Other Serious 10/18/2010 64 Male 11/10/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 8/11/2010 70 Male 11/10/2010 Physician Japan
Primary
Concomitant
Dizziness Other Serious 10/29/2010 76 Female 11/11/2010 Pharmacist Japan
Primary
Concomitant
Somnolence Other Serious 10/16/2010 39 Female 163 lb 11/13/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 10/18/2010 75 Male 11/19/2010 Physician Japan
Primary
Concomitant
Dizziness Other Serious 10/29/2010 76 Female 11/22/2010 Pharmacist Japan
Primary
Concomitant
Visual Impairment Other Serious 7/1/2010 76 Male 104 lb 11/24/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 9/27/2010 73 Female 11/24/2010 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 9/28/2010 73 Female 110 lb 12/2/2010 Pharmacist Japan
Primary
Concomitant
Loss Of Consciousness Other Serious 10/29/2010 76 Female 12/2/2010 Pharmacist Japan
Primary
Concomitant
Renal Impairment Other Serious 11/1/2010 77 Female 12/10/2010 Physician Japan
Primary
Secondary
Concomitant
Peripheral Nerve Palsy Other Serious 11/8/2010 74 Female 12/10/2010 Physician Japan
Primary
Concomitant
Fracture Other Serious 9/27/2010 72 Female 121 lb 12/14/2010 Physician Japan
Primary
Concomitant
Lung Neoplasm Malignant Death 81 Female 7/23/2010 Physician Japan
Primary
Concomitant
Chest Discomfort Other Serious 7/7/2010 88 Female 154 lb 8/24/2010 Physician Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2010 90 Female 86 lb 12/16/2010 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 11/4/2010 76 Female 68 lb 12/20/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Life Threatening 12/14/2010 62 Male 12/23/2010 Physician Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2010 90 Female 86 lb 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 12/1/2010 66 Female 119 lb 12/29/2010 Physician Japan
Primary
Concomitant
Cardio-respiratory Arrest Life Threatening 12/14/2010 62 Male 132 lb 12/30/2010 Physician Japan
Primary
Concomitant
Hypoaesthesia Hospitalization 12/10/2010 84 Female 12/30/2010 Pharmacist Japan
Primary
Concomitant
Apallic Syndrome Life Threatening 12/14/2010 62 Male 132 lb 1/5/2011 Consumer Japan
Primary
Concomitant
Muscular Weakness Hospitalization 12/1/2010 66 Female 119 lb 1/5/2011 Physician Japan
Primary
Concomitant
Apallic Syndrome Disability 12/14/2010 62 Male 132 lb 1/6/2011 Consumer Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 7/1/2010 90 Female 86 lb 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Death Death 12/1/2010 77 Female 1/12/2011 Pharmacist Japan
Primary
Concomitant
Convulsion Hospitalization 12/15/2010 57 Male 1/27/2011 Physician Japan
Primary
Secondary
Concomitant
Rectal Cancer Death 12/15/2010 57 Male 2/1/2011 Physician Japan
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 1/5/2011 58 Female 2/8/2011 Physician Japan
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 2/11/2011 75 Female 2/18/2011 Physician Japan
Primary
Concomitant
Faeces Discoloured 2/4/2011 52 Female 2/24/2011 Pharmacist Japan
Primary
Concomitant
Altered State Of Consciousness Other Serious 1/1/2011 62 Female 2/27/2011 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 59 Male 2/27/2011 Pharmacist Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 1/14/2011 89 Female 3/1/2011 Physician Japan
Primary
Concomitant
Condition Aggravated Other Serious 2/17/2011 3/2/2011 Physician Japan
Primary
Secondary
Loss Of Consciousness Hospitalization 1/28/2011 45 Male 127 lb 3/2/2011 Physician Japan
Primary
Concomitant
Radius Fracture Other Serious 2/13/2011 Male 3/3/2011 Pharmacist Japan
Primary
Concomitant
Melaena Hospitalization 7/15/2009 49 Female 165 lb 3/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Somnolence Death 2/17/2011 71 Female 3/8/2011 Physician Japan
Primary
Secondary
Rhabdomyolysis Hospitalization 11/19/2010 76 Male 119 lb 3/8/2011 Physician Japan
Primary
Concomitant
Fall Hospitalization 2/14/2011 60 Male 3/8/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Nausea Other Serious 11/2/2010 76 Female 3/8/2011 Physician Japan
Primary
Concomitant
Cardio-respiratory Arrest Death 12/14/2010 63 Male 132 lb 3/9/2011 Physician Japan
Primary
Concomitant
Dizziness Other Serious 2/21/2011 69 Male 3/9/2011 Pharmacist Japan
Primary
Concomitant
Weight Increased Other Serious 10/20/2010 78 Female 3/9/2011 Physician Japan
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 2/11/2011 75 Female 3/10/2011 Physician Japan
Primary
Concomitant
Condition Aggravated Other Serious 2/17/2011 71 Female 3/11/2011 Physician Japan
Primary
Secondary
Fall Other Serious 2/14/2011 60 Male 3/11/2011 Physician Japan
Primary
Secondary
Concomitant
Nausea Death 2/17/2011 71 Female 3/15/2011 Physician Japan
Primary
Secondary
Interstitial Lung Disease Other Serious 3/1/2011 82 Female 3/17/2011 Pharmacist Japan
Primary
Concomitant
Infection Other Serious 11/2/2010 76 Female 3/21/2011 Physician Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 1/14/2011 89 Female 66 lb 3/23/2011 Physician Japan
Primary
Concomitant
Epilepsy Hospitalization Male 3/23/2011 Pharmacist Japan
Primary
Concomitant
Epilepsy Hospitalization Male 3/25/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 3/1/2011 82 Female 3/29/2011 Pharmacist Japan
Primary
Concomitant
Weight Increased Other Serious 3/28/2011 77 Male 3/31/2011 Physician Japan
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 3/17/2011 72 Female 104 lb 3/31/2011 Physician Japan
Primary
Concomitant
Rhabdomyolysis Death 11/19/2010 76 Male 119 lb 4/1/2011 Physician Japan
Primary
Concomitant
Cystitis Other Serious 12/11/2010 65 Female 4/4/2011 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Death 1/28/2011 45 Male 127 lb 4/1/2011 Physician Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2011 42 Female 68 lb 4/8/2011 Physician Japan
Primary
Secondary
Concomitant
Back Pain Other Serious 1/25/2011 71 Female 4/13/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 1/27/2011 59 Male 136 lb 4/13/2011 Pharmacist Japan
Primary
Concomitant
Dysarthria Hospitalization 1/27/2011 59 Male 136 lb 4/15/2011 Pharmacist Japan
Primary
Concomitant
Anaphylactic Shock Life Threatening 3/23/2011 63 Male 110 lb 4/18/2011 Physician Japan
Primary
Concomitant
Altered State Of Consciousness Life Threatening 3/6/2011 82 Female 93 lb 4/19/2011 Physician Japan
Primary
Concomitant
Delirium Other Serious 11/2/2010 76 Female 4/20/2011 Physician Japan
Primary
Concomitant
Death Other Serious 3/28/2011 90 Female 4/21/2011 Physician Japan
Primary
Secondary
Tremor Hospitalization 3/15/2011 69 Female 93 lb 4/20/2011 Physician Japan
Primary
Concomitant
Influenza Hospitalization 11/22/2010 67 Male 4/22/2011 Physician Japan
Primary
Secondary
Concomitant
Headache Death 1/25/2011 71 Female 4/29/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/7/2011 79 Male 4/28/2011 Physician Japan
Primary
Secondary
Blood Pressure Decreased Other Serious 3/28/2011 90 Female 4/29/2011 Physician Japan
Primary
Secondary
Blood Creatine Phosphokinase Increased Other Serious 1/5/2011 58 Female 143 lb 5/4/2011 Physician Japan
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 1/5/2011 58 Female 143 lb 5/9/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Influenzal Hospitalization 11/22/2010 67 Male 5/12/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 4/7/2011 79 Male 5/11/2011 Physician Japan
Primary
Secondary
Aspartate Aminotransferase Increased Hospitalization 1/7/2011 58 Female 143 lb 5/13/2011 Physician Japan
Primary
Secondary
Concomitant
Melaena Other Serious 3/16/2011 90 Female 5/16/2011 Physician Japan
Primary
Secondary
Dysphonia Other Serious 2/21/2011 62 Female 5/18/2011 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/20/2011 51 Female 150 lb 5/18/2011 Other Health Professional Japan
Primary
Concomitant
Dizziness Hospitalization 4/26/2011 58 Female 110 lb 5/19/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Death 4/21/2011 78 Female 119 lb 5/23/2011 Physician Japan
Primary
Concomitant
Ulcerative Keratitis Other Serious 1/1/2011 86 Female 5/25/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Somnolence Death 1/25/2011 71 Female 5/26/2011 Physician Japan
Primary
Secondary
Concomitant
Atrioventricular Block Complete Hospitalization 2/11/2011 75 Female 5/27/2011 Physician Japan
Primary
Concomitant
Headache Death 1/25/2011 71 Female 5/31/2011 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 5/9/2011 52 Male 5/30/2011 Physician Japan
Primary
Concomitant
Dizziness Postural Other Serious 4/11/2011 82 Male 119 lb 5/31/2011 Physician Japan
Primary
Concomitant
Gastrointestinal Perforation Other Serious 5/22/2011 79 Male 6/1/2011 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 1/20/2011 51 Female 150 lb 6/6/2011 Other Health Professional Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 4/8/2011 83 Female 6/8/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 4/1/2011 64 Male 6/9/2011 Physician Japan
Primary
Concomitant
Glaucoma Other Serious 68 Female 6/9/2011 Pharmacist Japan
Primary
Concomitant
Tinnitus Other Serious 4/1/2011 64 Male 137 lb 6/9/2011 Physician Japan
Primary
Secondary
Concomitant
Aortic Dissection Life Threatening 5/2/2011 75 Female 6/13/2011 Other Health Professional Japan
Primary
Concomitant
Cardiac Failure Other Serious 5/30/2011 Male 6/15/2011 Other Health Professional Japan
Primary
Secondary
Dizziness Other Serious 4/1/2011 64 Male 137 lb 6/15/2011 Physician Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 4/24/2011 64 Male 137 lb 6/16/2011 Physician Japan
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious 68 Female 6/19/2011 Pharmacist Japan
Primary
Concomitant
Somnolence Hospitalization 4/24/2011 64 Male 137 lb 6/20/2011 Physician Japan
Primary
Secondary
Concomitant
Sinus Arrest Other Serious 6/3/2011 69 Male 6/22/2011 Physician Japan
Primary
Secondary
Encephalopathy Life Threatening 1/1/2011 64 Male 137 lb 6/23/2011 Physician Japan
Primary
Secondary
Concomitant
Acidosis Other Serious 6/3/2011 69 Male 6/24/2011 Physician Japan
Primary
Secondary
Csf Pressure Decreased Hospitalization 4/24/2011 64 Male 137 lb 6/29/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 10/29/2010 51 Male 146 lb 6/29/2011 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/22/2011 51 Male 146 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/26/2011 85 Male 7/6/2011 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 11/22/2010 67 Male 7/12/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 7/11/2011 74 Male 154 lb 7/14/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 5/1/2011 64 Male 108 lb 7/15/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Death 4/21/2011 78 Female 119 lb 7/14/2011 Physician Japan
Primary
Concomitant
Somnolence Other Serious 1/1/2011 65 Male 137 lb 7/18/2011 Physician Japan
Primary
Concomitant
Altered State Of Consciousness Hospitalization 5/26/2011 87 Female 93 lb 7/17/2011 Physician Japan
Primary
Concomitant
Pulmonary Embolism Death 4/21/2011 78 Female 119 lb 7/20/2011 Physician Japan
Primary
Concomitant
Neurogenic Bladder Other Serious 12/11/2010 65 Female 7/21/2011 Physician Japan
Primary
Concomitant
Decreased Appetite Life Threatening 1/1/2011 65 Male 137 lb 7/25/2011 Physician Japan
Primary
Concomitant
Generalised Oedema Other Serious 7/9/2011 86 Male 7/27/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 3/18/2011 64 Male 132 lb 7/29/2011 Consumer Japan
Primary
Concomitant

Drug Data