Losartan combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Photopsia Hospitalization 72 Female 6/25/2007 Japan
Primary
Secondary
Concomitant
Oesophagitis Life Threatening 12/19/2007 86 Female 1/22/2008 United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 75 Male 176 lb 7/3/2008 Physician Brazil
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 1 Male 35 lb 9/24/2008 Other Health Professional Canada
Primary
Concomitant
Thrombocytopenia Other Serious 5/1/2007 Male 35 lb 9/24/2008 Other Health Professional Canada
Primary
Concomitant
Pulmonary Embolism Other Serious 1 Male 35 lb 9/29/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Muscle Disorder Other Serious 11/1/2006 78 Female 9/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 78 Female 10/8/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 78 Female 10/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscle Disorder Other Serious 11/1/2006 78 Female 10/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 1 Male 35 lb 10/13/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 78 Female 10/23/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2006 78 Female 10/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 1 Male 12/22/2008 Other Health Professional Canada
Primary
Concomitant
Ventricular Tachycardia Other Serious 56 Male 1/5/2009 Physician India
Primary
Concomitant
Venous Pressure Jugular Increased Other Serious 56 Male 1/30/2009 Other Health Professional India
Primary
Concomitant
Ventricular Dysfunction Other Serious 2/23/2009 Other Health Professional Italy
Primary
Concomitant
Ventricular Dysfunction Other Serious 61 Male 2/24/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 10/29/2002 Female 3/9/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 65 Female 167 lb 7/22/2009 Lawyer United States
Primary
Concomitant
Renal Impairment Hospitalization 6/1/2009 79 Male 8/7/2009 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/13/2006 65 Female 167 lb 8/5/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 77 Female 8/24/2009 Other Health Professional Netherlands
Primary
Concomitant
Interacting
Ventricular Tachycardia Hospitalization 72 Male 8/31/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 72 Male 9/4/2009 United States
Primary
Concomitant
Somnolence Disability 9/1/2009 77 Female 9/18/2009 Consumer Colombia
Primary
Concomitant
Cardiac Arrest Death 70 Male 9/23/2009
Primary
Secondary
Renal Failure Other Serious 72 10/5/2009 Physician Brazil
Primary
Concomitant
Hyperkalaemia Required Intervention 5/11/2009 79 Male 223 lb 10/2/2009 Pharmacist United States
Primary
Secondary
Renal Failure Acute Hospitalization 9/9/2009 Male 10/22/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 72 Male 10/16/2009 Lawyer United States
Primary
Concomitant
Haematoma Hospitalization 1/29/2009 Male 12/7/2009 Pharmacist France
Primary
Secondary
Concomitant
Haematoma Hospitalization 1/29/2009 Male 12/8/2009 Pharmacist France
Primary
Secondary
Concomitant
Haemoglobin Decreased Required Intervention 10/26/2009 56 Male 130 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 56 Male 12/17/2009 Other Health Professional
Primary
Concomitant
Tremor Hospitalization 7/1/2010 80 Female 8/3/2010 Consumer Colombia
Primary
Concomitant
Staphylococcal Infection Other Serious 2/1/2008 75 Female 170 lb 8/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Proteinuria Other Serious 8/11/2010 55 Female 10/8/2010 Other Health Professional Brazil
Primary
Concomitant
Poor Peripheral Circulation Other Serious 1/1/2010 69 Female 10/15/2010 Consumer Brazil
Primary
Concomitant
Polymyositis Hospitalization 1/1/2009 70 Female 10/29/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious Female 141 lb 11/2/2010 Physician United Kingdom
Primary
Concomitant
Proteinuria Other Serious 8/11/2010 55 Female 11/3/2010 Other Health Professional Brazil
Primary
Concomitant
Vertigo Male 11/16/2010 Consumer United States
Primary
Concomitant
Pelvic Mass Hospitalization 4/17/2009 75 Female 197 lb 11/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Off Label Use Other Serious Male 250 lb 12/3/2010 Consumer United States
Primary
Concomitant
Rash Erythematous Hospitalization 9/15/2010 60 Female 12/8/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization 8/12/2010 60 Female 154 lb 12/10/2010 Consumer Brazil
Primary
Concomitant
Epistaxis Hospitalization 7/24/2010 78 Male 200 lb 8/4/2010 Pharmacist United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2010 60 Female 12/27/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/6/2010 84 Female 143 lb 12/27/2010 Physician
Primary
Concomitant
Cardiac Failure Hospitalization 9/1/2010 86 Female 227 lb 12/29/2010 Physician Netherlands
Primary
Concomitant
Dizziness 12/8/2010 80 Female 1/13/2011 Consumer
Primary
Concomitant
Weight Increased 12/1/2010 71 Male 269 lb 1/14/2011 Consumer
Primary
Concomitant
Renal Impairment Other Serious 1/1/2007 78 Female 106 lb 1/27/2011 Consumer Argentina
Primary
Concomitant
Eye Pruritus Other Serious 12/4/2008 67 Male 254 lb 2/17/2011 Other Health Professional United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 10/1/2010 15 Female 2/22/2011 Physician United States
Primary
Concomitant
Pelvic Mass Hospitalization 4/17/2009 75 Female 197 lb 2/25/2011 Other Health Professional United Kingdom
Primary
Concomitant
Acute Myeloid Leukaemia Death 2/11/2009 67 Male 3/15/2011 Consumer Israel
Primary
Secondary
Concomitant
Leg Amputation Hospitalization 1/1/2010 69 Female 3/17/2011 Consumer Brazil
Primary
Concomitant
Urine Odour Abnormal Hospitalization 9/28/2007 4/11/2011 Other Health Professional United States
Primary
Concomitant
Pelvic Mass Hospitalization 4/1/2009 75 Female 197 lb 4/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 4/8/2011 71 Male 271 lb 4/13/2011 Pharmacist United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 2/11/2009 67 Male 197 lb 5/4/2011 Physician Israel
Primary
Secondary
Concomitant
Pelvic Mass Hospitalization 4/1/2009 75 Female 197 lb 5/6/2011 Other Health Professional United Kingdom
Primary
Concomitant
Tachypnoea Other Serious 12/19/2010 53 Female 228 lb 5/9/2011 Physician United States
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 2/11/2009 67 Male 197 lb 5/11/2011 Consumer Israel
Primary
Secondary
Concomitant
Keratopathy Other Serious 80 Female 7/7/2011 Physician United States
Primary
Concomitant
Keratopathy Other Serious 80 Female 7/13/2011 Physician United States
Primary
Concomitant
Cardiac Failure Hospitalization 5/18/2011 75 Male 185 lb 7/15/2011 Physician Brazil
Primary
Concomitant
Flatulence 5/19/2011 82 Male 201 lb 7/19/2011 Consumer United States
Primary
Concomitant
Blood Glucose Fluctuation 6/1/2011 82 Female 8/23/2011 Consumer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 2/1/2011 61 Female 270 lb 8/30/2011 Physician United States
Primary
Concomitant
Asthenia Other Serious 5/1/2011 70 Female 230 lb 9/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Headache Other Serious 8/2/2011 27 Female 119 lb 9/1/2011 Consumer Brazil
Primary
Concomitant
Blood Pressure Increased Death 11/2/2010 86 Male 9/5/2011 Brazil
Primary
Concomitant
Cardiac Failure Hospitalization 5/18/2011 75 Male 185 lb 9/6/2011 Physician Brazil
Primary
Concomitant
Bundle Branch Block Left Other Serious 34 Male 216 lb 11/4/2011 Physician Brazil
Primary
Secondary
Musculoskeletal Discomfort 8/25/2011 79 Female 141 lb 11/8/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/18/2011 75 Male 185 lb 11/21/2011 Physician Brazil
Primary
Concomitant
Fatigue Hospitalization 66 Male 12/28/2011 Physician Sweden
Primary
Concomitant
Hypoacusis Other Serious Male 1/24/2012 Consumer United States
Primary
Concomitant
Drug Interaction Hospitalization 11/5/2011 66 Male 2/3/2012 Physician Sweden
Primary
Concomitant
Interacting
Overdose Other Serious 6/25/2011 86 Male 2/17/2012 Physician Denmark
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 11/5/2011 66 Male 2/23/2012 Physician Sweden
Primary
Concomitant
Interacting
Hypotension Hospitalization 11/9/2011 60 Female 106 lb 3/1/2012 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 11/9/2011 60 Female 106 lb 3/6/2012 Physician United States
Primary
Secondary
Concomitant
Drug Effect Decreased Male 240 lb 3/23/2012 Consumer United States
Primary
Concomitant
Drug Ineffective Male 240 lb 3/27/2012 Consumer United States
Primary
Concomitant
Tobacco User Other Serious 9/1/2011 60 Male 298 lb 4/13/2012 Consumer United States
Primary
Concomitant
Abdominal Discomfort 1/1/2012 79 Male 4/19/2012 Physician United States
Primary
Concomitant
Nephrotic Syndrome Hospitalization 4/30/2012 65 Male 181 lb 6/1/2012 Physician Chile
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 5/11/2012 73 Male 6/28/2012 Consumer United States
Primary
Concomitant
Orthopnoea Other Serious 6/17/2008 70 Male 7/12/2012 Physician Colombia
Primary
Secondary
Concomitant
Haematuria Other Serious 6/25/2011 76 Male 7/17/2012 Physician Colombia
Primary
Concomitant
Pruritus Other Serious 6/25/2012 51 Female 253 lb 7/30/2012 Consumer United States
Primary
Secondary
Concomitant
Rash Other Serious 7/1/2012 51 Female 253 lb 8/7/2012 Consumer United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 10/1/2007 81 Female 8/7/2012 Consumer Brazil
Primary
Concomitant
Hallucination, Visual Hospitalization 6/24/2012 77 Female 8/24/2012 Physician United Kingdom
Primary
Concomitant
Varicose Ulceration Hospitalization 3/2009 58 Female 10/30/2012 Consumer Co
Primary
Concomitant
Wound Infection Death 1/25/2012 73 Female 12/3/2012 Consumer Country Not Specified
Primary
Concomitant
Thrombosis Other Serious 2011 58 Female 165 lb 3/11/2013 Consumer Br
Primary
Concomitant
Renal Failure Other Serious 6/30/2012 71 Male 257 lb 8/29/2012 Consumer Us
Primary
Concomitant
Mobility Decreased Other Serious 11/2010 87 Male 9/18/2012 Consumer Us
Primary
Concomitant
Stress Other Serious 1/8/2011 82 Female 1/23/2013 Consumer Us
Primary
Secondary
Prostate Cancer Hospitalization 74 Male 9/17/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/12/2012 82 Female 9/7/2012 Pharmacist Br
Primary
Concomitant
Pyrexia Other Serious 8/2012 37 Female 10/2/2012 Consumer Country Not Specified
Primary
Concomitant
Vomiting Other Serious 5/2012 63 Female 1/7/2013 Consumer Us
Primary
Secondary
Concomitant
Pruritus 8/10/2011 71 Male 9/5/2012 Consumer Us
Primary
Concomitant
Blood Potassium Increased Hospitalization 8/16/2012 63 Male 12/21/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Gout 8/2012 Male 9/12/2012 Consumer Us
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 66 Male 185 lb 10/29/2012 Physician Us
Primary
Concomitant
Lung Disorder 6/2012 Female 161 lb 9/24/2012 Consumer Us
Primary
Concomitant
Back Pain 8/2012 82 Female 9/27/2012 Consumer Us
Primary
Concomitant
Thrombosis Hospitalization 7/2012 Male 10/5/2012 Consumer Us
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 10/5/2012 85 Female 12/26/2012 Physician Ph
Primary
Concomitant
Hypertension Hospitalization 12/2011 Female 209 lb 10/29/2012 Other Health Professional Us
Primary
Concomitant
Pollakiuria 60 Male 268 lb 11/2/2012 Consumer Us
Primary
Concomitant
Weight Decreased Other Serious 8/2012 62 Female 291 lb 12/17/2012 Consumer Us
Primary
Concomitant
Hiatus Hernia 72 Male 11/20/2012 Us
Primary
Concomitant
Weight Loss Poor 52 Female 235 lb 11/20/2012 Us
Primary
Concomitant
Gingival Pain 79 Female 165 lb 11/1/2012 Consumer Us
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 9/8/2012 78 Male 248 lb 9/12/2012 Pharmacist Us
Primary
Secondary
Concomitant
Pruritus 5/7/2012 69 Female 11/28/2012 Pharmacist Us
Primary
Concomitant
Paralysis Other Serious 7/2012 79 Female 165 lb 12/7/2012 Physician At
Primary
Secondary
Concomitant
Dyspnoea Other Serious 11/2012 Male 12/26/2012 Consumer Us
Primary
Concomitant
Vomiting Other Serious 11/28/2011 71 Female 12/17/2012 Consumer Us
Primary
Concomitant
Transient Ischaemic Attack Other Serious NotSpecified 1/4/2013 Other Health Professional Nz
Primary
Concomitant
Trigger Finger Other Serious 7/2012 54 Female 2/1/2013 Consumer Ca
Primary
Concomitant
Device Related Infection Hospitalization 12/10/2012 82 Female 155 lb 2/12/2013 Physician Us
Primary
Concomitant
Dyspnoea Hospitalization 7/2012 Male 330 lb 1/3/2013 Consumer Us
Primary
Concomitant
Syncope Hospitalization 11/27/2012 70 Female 1/2/2013 Physician It
Primary
Concomitant
Interacting
Syncope Hospitalization 11/27/2012 70 Female 1/7/2013 Physician It
Primary
Concomitant
Interacting
Transient Ischaemic Attack Other Serious 87 Female 12/28/2012 Other Health Professional Nz
Primary
Concomitant
Transient Ischaemic Attack Other Serious 87 Female 1/7/2013 Nz
Primary
Concomitant
Panniculitis Hospitalization 7/30/2012 55 Female 213 lb 12/13/2012 Other Health Professional Us
Primary
Concomitant
Injection Site Pain 6/20/2012 37 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 7/5/2012 88 Female 2/11/2013 Physician Es
Primary
Concomitant
Interacting
Refusal Of Treatment By Patient Hospitalization 2/2/2013 63 Male 181 lb 2/15/2013 Consumer Mx
Primary
Concomitant
Left Ventricular Hypertrophy Hospitalization 36 Male 2/6/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Tendon Rupture 5/2012 Female 245 lb 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Other Serious 2/2012 69 Male 11/12/2013 Consumer Country Not Specified
Primary
Concomitant
Pulmonary Toxicity Hospitalization 1/31/2013 66 Male 152 lb 3/8/2013 Physician Us
Primary
Secondary
Concomitant
Pallor Hospitalization 2/1/2013 75 Female 3/1/2013 Consumer Us
Primary
Concomitant
Wrong Drug Administered Other Serious Male 10/18/2013 Physician Gb
Primary
Secondary
Urinary Tract Infection Other Serious 2009 Female 345 lb 2/22/2013 Physician Us
Primary
Secondary
Concomitant
Disease Progression Death 1/16/2013 72 Male 2/15/2013 Pharmacist Us
Primary
Concomitant
Drug Ineffective 2/14/2013 55 Male 3/4/2013 Other Health Professional Us
Primary
Concomitant
Respiratory Failure Death 11/3/2012 76 Female 106 lb 3/6/2013 Physician Gb
Primary
Concomitant

Drug Data