Losartan Potassium combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypertension Hospitalization 1/16/2006 Female 1/31/2006 Physician United States
Primary
Concomitant
Hyperkalaemia Life Threatening 11/22/2005 65 Male 298 lb 11/28/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/1/2006 96 Female 132 lb 2/23/2006 Other Health Professional Brazil
Primary
Concomitant
Scrotal Swelling Hospitalization 2/1/2006 76 Male 3/23/2006 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 12/28/2005 65 Female 3/31/2006 Switzerland
Primary
Secondary
Concomitant
Rash Required Intervention 4/6/2006 83 Male 184 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Postoperative Infection Hospitalization 89 Female 7/7/2006 Physician United States
Primary
Secondary
Vitamin B12 Deficiency Other Serious 74 Male 7/3/2006 United States
Primary
Concomitant
Postoperative Infection Hospitalization 89 Female 7/11/2006 Physician United States
Primary
Secondary
Pancytopenia Required Intervention 74 Male 7/5/2006 Physician United States
Primary
Concomitant
Gastrointestinal Toxicity Hospitalization 4/1/2006 74 Female 159 lb 8/8/2006 Consumer Mexico
Primary
Concomitant
Myocarditis Hospitalization 7/1/2002 Male 8/25/2006 Physician Japan
Primary
Secondary
Concomitant
Erythema Hospitalization 7/26/2006 75 Female 9/1/2006 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Toxicity Hospitalization 4/1/2006 74 Female 159 lb 9/12/2006 Consumer Mexico
Primary
Concomitant
Hyperlipidaemia Other Serious 7/1/2002 Male 11/1/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/21/2006 75 Female 11/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 11/30/2006 55 Male 197 lb 12/4/2006 Pharmacist United States
Primary
Secondary
Pallor Hospitalization 10/15/2006 84 Female 12/19/2006 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 56 Male 3/6/2007 Other Health Professional France
Primary
Concomitant
Myositis Other Serious 2/1/2007 64 Female 220 lb 3/14/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 76 Female 4/9/2007 Consumer Colombia
Primary
Concomitant
Rash Other Serious Female 200 lb 4/27/2007 Physician United States
Primary
Concomitant
Interacting
Respiration Abnormal Life Threatening 89 Male 5/16/2007 Physician Japan
Primary
Secondary
Concomitant
Sensation Of Heaviness Hospitalization 12/25/2005 68 Male 5/17/2007 Consumer New Zealand
Primary
Concomitant
Visual Acuity Reduced Hospitalization 72 Female 115 lb 6/22/2007
Primary
Secondary
Photopsia Hospitalization 72 Female 6/28/2007 Japan
Primary
Secondary
Concomitant
Thrombosis In Device Hospitalization 67 Male 7/3/2007 United States
Primary
Secondary
Concomitant
Thrombosis In Device Hospitalization 67 Male 7/2/2007 United States
Primary
Secondary
Concomitant
Tremor Other Serious 6/28/2007 64 Female 126 lb 7/19/2007 Consumer Brazil
Primary
Concomitant
Nausea Other Serious 7/16/2007 Female 280 lb 7/27/2007 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/28/2007 64 Female 126 lb 8/3/2007 Consumer Brazil
Primary
Concomitant
Urinary Tract Infection Other Serious 6/28/2007 64 Female 130 lb 8/10/2007 Consumer Brazil
Primary
Concomitant
Visual Acuity Reduced Hospitalization 72 Female 115 lb 8/21/2007 Physician Japan
Primary
Concomitant
Respiration Abnormal Life Threatening 89 Male 8/24/2007 Physician Japan
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 5/1/2007 81 Female 8/23/2007 Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 6/28/2007 64 Female 130 lb 9/10/2007 Consumer Brazil
Primary
Concomitant
Hiatus Hernia Hospitalization 9/18/2007 84 Female 10/31/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Nasopharyngitis 11/23/2007 Male 12/3/2007 Consumer United States
Primary
Concomitant
Nasopharyngitis 11/23/2007 Male 12/5/2007 Consumer United States
Primary
Concomitant
Photosensitivity Reaction Other Serious 56 Female 12/19/2007 Other Health Professional Spain
Primary
Secondary
Photosensitivity Reaction Other Serious 56 Female 12/27/2007 Other Health Professional Spain
Primary
Secondary
Oesophagitis Life Threatening 12/19/2007 86 Female 1/9/2008 United Kingdom
Primary
Secondary
Concomitant
Rash Hospitalization 10/3/2006 85 Female 11/29/2007 Consumer United States
Primary
Concomitant
Nasopharyngitis 11/23/2007 Male 2/12/2008 Consumer United States
Primary
Concomitant
Renal Failure Chronic Death 11/11/2007 Male 2/21/2008 Pharmacist United States
Primary
Concomitant
Mass 1/1/2008 Female 114 lb 3/15/2008 Consumer United States
Primary
Concomitant
Orthopnoea Other Serious 2/25/2008 69 Male 201 lb 4/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 10/10/2007 Female 250 lb 4/30/2008 Physician United States
Primary
Concomitant
Lipodystrophy Acquired Hospitalization 1/8/2008 Male 172 lb 5/2/2008 Physician Brazil
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 53 Female 5/13/2008 Physician Nepal
Primary
Secondary
Concomitant
Cardiac Failure Death 1/1/2003 60 Female 110 lb 5/22/2008 Physician Japan
Primary
Concomitant
Underdose Other Serious 7/1/2001 Male 287 lb 6/12/2008 Physician United States
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Hospitalization 5/1/2008 Male 287 lb 6/13/2008 Physician United States
Primary
Concomitant
Interacting
Lipohypertrophy Hospitalization 3/10/2008 Male 172 lb 7/21/2008 Physician Brazil
Primary
Secondary
Concomitant
Hypomagnesaemia Other Serious 11/1/2006 78 Female 7/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hyperkalaemia Hospitalization 10/5/2007 71 Female 7/25/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2006 78 Female 8/3/2008 United Kingdom
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 6/18/2008 80 Female 8/7/2008 Other Health Professional France
Primary
Concomitant
Vomiting Other Serious 78 Female 8/8/2008 United Kingdom
Primary
Concomitant
Cardiac Failure Other Serious 61 Male 8/27/2008 United States
Primary
Concomitant
Pain Of Skin 8/16/2007 Female 185 lb 8/27/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Life Threatening 5/1/2007 Male 8/27/2008 Canada
Primary
Concomitant
Septic Shock Death 92 Female 110 lb 9/11/2008 Consumer Brazil
Primary
Concomitant
Pulmonary Embolism Other Serious 1 Male 35 lb 9/12/2008 Other Health Professional Canada
Primary
Concomitant
Muscle Disorder Other Serious 11/1/2006 78 Female 9/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Required Intervention 78 Female 11/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 61 Male 11/21/2008 Italy
Primary
Concomitant
Pneumonia Life Threatening 10/1/2008 65 Female 12/9/2008 Physician Austria
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Hospitalization 5/1/2008 59 Male 288 lb 1/7/2009 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 3/20/2008 61 Female 2/5/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 78 Female 3/26/2009 United Kingdom
Primary
Concomitant
Pruritus Hospitalization 1/8/2009 Male 4/1/2009 Pharmacist France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/9/2009 60 Male 4/1/2009 Physician United Kingdom
Primary
Concomitant
Haematoma Hospitalization 1/29/2009 Male 4/7/2009 Pharmacist France
Primary
Secondary
Concomitant
Sudden Death Death 3/20/2008 61 Female 4/16/2009 Physician Japan
Primary
Concomitant
Organising Pneumonia Hospitalization 9/1/2008 71 Female 5/29/2009 Physician Japan
Primary
Concomitant
Organising Pneumonia Hospitalization 9/1/2008 71 Female 6/9/2009 Consumer Japan
Primary
Concomitant
Cardiac Arrest Death 70 Male 6/22/2009 Other Health Professional Netherlands
Primary
Concomitant
Hypoglycaemia Required Intervention 3/31/2009 Male 200 lb 4/11/2009 Pharmacist United States
Primary
Concomitant
Pruritus 1/1/2005 Female 8/21/2009 United States
Primary
Concomitant
Incorrect Dose Administered 4/2/2007 Female 115 lb 9/11/2009 Consumer United States
Primary
Concomitant
Hypoglycaemia Hospitalization 50 Male 161 lb 12/8/2009 Physician Japan
Primary
Secondary
Concomitant
Hypophagia Hospitalization 1/29/2010 63 Male 181 lb 2/2/2010 Physician United States
Primary
Concomitant
Generalised Oedema Other Serious 2/7/2010 81 Male 3/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 2/1/2005 50 Male 161 lb 3/12/2010 Other Health Professional Japan
Primary
Concomitant
Generalised Oedema Other Serious 2/7/2010 81 Male 3/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Generalised Oedema Other Serious 2/7/2010 81 Male 3/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Generalised Oedema Other Serious 2/7/2010 81 Male 3/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Generalised Oedema Other Serious 2/7/2010 81 Male 3/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Generalised Oedema Other Serious 81 Male 3/22/2010 Other Health Professional
Primary
Concomitant
International Normalised Ratio Increased Other Serious 77 Female 4/14/2010 Other Health Professional Netherlands
Primary
Concomitant
Interacting
Hepatic Neoplasm Life Threatening 76 Female 4/22/2010 Physician Philippines
Primary
Concomitant
Visual Acuity Reduced Disability Female 5/11/2010 France
Primary
Concomitant
Haematoma Hospitalization 1/29/2009 83 Male 5/12/2010 Pharmacist France
Primary
Secondary
Concomitant
Thrombosis In Device Other Serious 2/19/2010 69 Male 5/18/2010 Pharmacist United States
Primary
Secondary
Concomitant
Thrombosis In Device Other Serious 2/9/2010 69 Male 5/19/2010 Pharmacist France
Primary
Secondary
Concomitant
Thrombosis In Device Other Serious 2/9/2010 69 Male 5/24/2010 Pharmacist France
Primary
Secondary
Concomitant
Vascular Graft Thrombosis Other Serious 2/9/2010 70 Male 5/26/2010 Pharmacist United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 2/13/2008 75 Female 170 lb 6/10/2010 Lawyer United States
Primary
Concomitant
Hypotension Hospitalization 6/1/2010 82 Male 185 lb 6/8/2010 Pharmacist United States
Primary
Secondary
Stomatitis Hospitalization 6/16/2009 76 Male 176 lb 7/21/2010 Physician Japan
Primary
Concomitant
Jaundice Other Serious 3/17/2010 70 Female 7/27/2010 Japan
Primary
Concomitant
Depressed Level Of Consciousness Hospitalization 12/25/2008 76 Male 115 lb 8/17/2010 Japan
Primary
Concomitant
Inappropriate Schedule Of Drug Administration 1/1/2010 73 Female 170 lb 9/2/2010 Consumer United States
Primary
Secondary
Concomitant
Deafness Other Serious 8/25/2010 59 Female 9/8/2010 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Hospitalization 50 Male 161 lb 9/10/2010 Physician Japan
Primary
Secondary
Concomitant
Fatigue Hospitalization 8/16/2010 60 Female 9/15/2010 Consumer Mexico
Primary
Concomitant
Tremor Hospitalization 7/11/2010 80 Female 9/16/2010 Consumer Colombia
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 9/3/2010 United States
Primary
Concomitant
Infection Hospitalization 3/25/2010 58 Female 9/20/2010 Sweden
Primary
Concomitant
Thrombosis In Device Other Serious 2/9/2010 69 Male 9/21/2010 Pharmacist France
Primary
Secondary
Concomitant
Vascular Graft Thrombosis Hospitalization 1/1/2010 70 Male 174 lb 9/23/2010 Pharmacist United States
Primary
Secondary
Concomitant
Thrombosis In Device Other Serious 1/1/2010 69 Male 9/24/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Stomatitis Hospitalization 6/16/2009 76 Male 176 lb 9/20/2010 Other Health Professional Japan
Primary
Concomitant
Mechanical Ventilation Hospitalization 12/25/2008 76 Male 115 lb 10/5/2010 Physician Japan
Primary
Concomitant
Muscle Spasms 10/1/2010 80 Female 204 lb 12/16/2010 Physician United States
Primary
Secondary
Concomitant
Mechanical Ventilation Hospitalization 12/25/2008 76 Male 115 lb 12/27/2010 Physician Japan
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 9/15/2010 60 Female 1/10/2011 Physician United States
Primary
Secondary
Concomitant
Hypotension Other Serious 2/1/2008 75 Female 170 lb 2/3/2011 Lawyer United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 2/11/2009 67 Male 2/11/2011 Physician Israel
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 9/1/2010 86 Female 227 lb 2/15/2011 Physician Netherlands
Primary
Concomitant
Pulmonary Fibrosis Death 7/10/2009 78 Female 101 lb 2/15/2011 Physician Japan
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 2/11/2009 67 Male 197 lb 2/16/2011 Physician Israel
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 2/11/2009 67 Male 2/16/2011 Physician Israel
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 7/28/2010 81 Female 108 lb 2/22/2011 Physician Japan
Primary
Concomitant
Activities Of Daily Living Impaired 12/8/2010 80 Female 2/27/2011 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Death 2/11/2009 67 Male 2/28/2011 Consumer Israel
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 2/11/2009 67 Male 197 lb 2/28/2011 Physician Israel
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 9/1/2010 86 Female 227 lb 3/2/2011 Physician Netherlands
Primary
Concomitant
White Blood Cell Count Decreased Death 2/11/2009 67 Male 197 lb 3/11/2011 Physician Israel
Primary
Secondary
Concomitant
Insomnia 12/20/2010 66 Female 3/18/2011 Consumer United States
Primary
Concomitant
Acute Myeloid Leukaemia Death 2/11/2009 67 Male 3/22/2011 Consumer Israel
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 3/15/2011 77 Male 194 lb 3/21/2011 Pharmacist United States
Primary
Concomitant
Abdominal Distension Hospitalization 9/28/2007 3/23/2011 Physician United States
Primary
Concomitant
Pulmonary Arterial Hypertension Death 3/8/2011 76 Female 3/29/2011 Other Health Professional United States
Primary
Concomitant
Feeling Cold Hospitalization 60 Female 163 lb 4/1/2011 Consumer Denmark
Primary
Concomitant
Constipation Other Serious 1/1/2006 71 Female 120 lb 4/1/2011 Consumer United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 3/1/2011 63 Female 165 lb 4/5/2011 Consumer Brazil
Primary
Concomitant
Paraesthesia Life Threatening 54 Male 150 lb 4/7/2011 Physician United Kingdom
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 7/28/2010 81 Female 108 lb 4/15/2011 Physician Japan
Primary
Concomitant
Dizziness Postural Other Serious 12/1/2010 69 Female 4/19/2011 Consumer Denmark
Primary
Concomitant
Food Poisoning Hospitalization 1/1/2007 49 Female 4/26/2011 Consumer Netherlands
Primary
Concomitant
Fatigue Hospitalization 1/7/2011 63 Female 139 lb 4/26/2011 Other Health Professional United States
Primary
Concomitant
Ill-defined Disorder 6/15/2010 67 Female 5/25/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Death 9/26/2006 56 Female 132 lb 6/1/2011 Consumer United States
Primary
Concomitant
Death Death 3/25/2010 58 Female 6/3/2011 Consumer Sweden
Primary
Concomitant
Feeling Cold Hospitalization 3/7/2011 60 Female 163 lb 6/13/2011 Consumer Denmark
Primary
Concomitant
Somnolence Hospitalization 1/1/2011 58 Female 6/21/2011 Other Health Professional United States
Primary
Concomitant
Fall Other Serious 5/1/2011 70 Female 230 lb 6/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Immunoglobulin G Decreased Hospitalization 7/1/2006 51 Male 148 lb 6/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data