Lorazepam combined with Zopiclone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tachycardia Hospitalization 53 Male 1/25/2006 Other Health Professional Canada
Primary
Concomitant
Respiration Abnormal Hospitalization 1/31/2006 40 Female 2/16/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 6/1/2003 58 Female 141 lb 2/24/2006 Lawyer Canada
Primary
Concomitant
Neuroleptic Malignant Syndrome Life Threatening 1/6/2006 23 Male 2/24/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Paranoia Other Serious 2/4/2006 20 Male 3/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Other Serious 2/14/2006 32 Female 3/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sleep Disorder Hospitalization 3/12/2006 52 Female 3/27/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 3/12/2006 52 Female 3/27/2006 Physician Finland
Primary
Secondary
Concomitant
Pancreatitis Life Threatening 3/1/2006 20 Female 3/23/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 3/12/2006 52 Female 4/6/2006 Physician Finland
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 3/12/2006 52 Female 4/6/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Stomach Discomfort Hospitalization 6/1/2003 58 Female 141 lb 4/7/2006 Physician Canada
Primary
Concomitant
Sleep Disorder Hospitalization 3/12/2006 52 Female 4/7/2006 Physician Finland
Primary
Secondary
Concomitant
Pancreatitis Life Threatening 3/1/2006 20 Female 3/31/2006 Germany
Primary
Secondary
Concomitant
Panic Disorder Hospitalization 1/1/2002 37 Female 214 lb 4/17/2006 Lawyer Canada
Primary
Concomitant
Treatment Noncompliance Death 9/18/2003 Male 4/20/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Death 9/18/2003 Male 4/27/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 3/22/2005 81 Female 4/27/2006 Canada
Primary
Concomitant
Venous Pressure Jugular Increased Hospitalization 53 Male 5/25/2005 Other Health Professional Canada
Primary
Concomitant
Therapy Non-responder Hospitalization 53 Male 5/25/2006 Other Health Professional Canada
Primary
Concomitant
Shock Other Serious 4/17/2006 78 Male 6/12/2006 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 3/25/2006 80 Male 6/30/2006 France
Primary
Concomitant
Rhabdomyolysis Death Male 154 lb 9/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Haemorrhage Other Serious 9/8/2006 42 Female 9/21/2006 Pharmacist Canada
Primary
Concomitant
Post Procedural Complication Hospitalization 8/5/2006 Female 104 lb 9/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 2/1/2005 76 Male 10/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Swelling Face Other Serious 8/7/2006 48 Male 11/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Restlessness Other Serious 11/8/2006 Consumer United Kingdom
Primary
Secondary
Overdose Death 45 Female 12/14/2006 Other Health Professional Canada
Primary
Concomitant
Rash Other Serious 10/21/2006 Male 231 lb 12/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Tremor Hospitalization 4/24/2002 Female 1/22/2007 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thermal Burn Other Serious Female 2/6/2007 Physician United Kingdom
Primary
Concomitant
Sudden Death Death 4/11/2007 16 Female 5/25/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/5/2001 85 Male 146 lb 5/31/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Obsessive-compulsive Disorder Hospitalization 11/21/2003 Female 7/3/2007 Physician Japan
Primary
Concomitant
Pancreatitis Acute Hospitalization 6/1/2006 Male 7/6/2007 Physician France
Primary
Concomitant
Obsessive-compulsive Disorder Hospitalization 11/21/2003 Female 7/9/2007 Physician Japan
Primary
Concomitant
Suicide Attempt Hospitalization 62 Male 7/27/2007 United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 7/15/2007 7/30/2007 Consumer United States
Primary
Secondary
Sleep Disorder Other Serious 7/21/2007 60 Female 8/1/2007 Consumer United Kingdom
Primary
Concomitant
Interacting
Suicide Attempt Life Threatening 62 Male 7/26/2007 United Kingdom
Primary
Secondary
Somnolence Other Serious 7/21/2007 60 Female 8/16/2007 Consumer United Kingdom
Primary
Concomitant
Interacting
Pain In Extremity Other Serious Male 8/20/2007 Other Health Professional France
Primary
Concomitant
Suicide Attempt Other Serious 7/6/2007 58 Female 8/6/2007 Physician Germany
Primary
Secondary
Suicide Attempt Other Serious 7/6/2007 58 Female 8/6/2007 Pharmacist Germany
Primary
Secondary
Suicide Attempt Other Serious 7/6/2007 58 Female 8/6/2007 Physician Germany
Primary
Secondary
Platelet Count Increased Other Serious 7/9/2007 50 Male 320 lb 8/23/2007 Physician United Kingdom
Primary
Concomitant
Suicide Attempt Other Serious 62 Male 8/24/2007 United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Life Threatening 62 Male 8/16/2007 United Kingdom
Primary
Secondary
Tongue Discolouration Hospitalization 7/15/2007 9/5/2007 Consumer United States
Primary
Secondary
Platelet Count Increased Other Serious 6/23/2007 50 Male 320 lb 9/13/2007 Physician United Kingdom
Primary
Concomitant
Sudden Death Death 4/11/2007 16 Female 9/14/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Ejaculation Failure Other Serious 7/25/2007 17 Male 10/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Suicide Attempt Other Serious 62 Male 10/3/2007 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 6/1/2006 Male 11/12/2007 Physician France
Primary
Concomitant
Subcutaneous Haematoma Other Serious 8/6/2007 59 Male 154 lb 11/14/2007 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 6/27/2007 60 Male 11/15/2007 Physician Taiwan, Province Of China
Primary
Concomitant
Mobility Decreased Other Serious 9/4/2007 83 Male 11/19/2007 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 6/27/2007 60 Male 12/8/2007 Physician Taiwan, Province Of China
Primary
Concomitant
Weight Decreased Hospitalization 6/27/2007 60 Male 12/20/2007 Physician Taiwan, Province Of China
Primary
Concomitant
Vision Blurred Hospitalization 4/24/2002 47 Female 1/10/2008 Physician United Kingdom
Primary
Concomitant
Tremor Other Serious 11/12/2007 1/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 11/12/2007 44 Female 128 lb 1/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 11/12/2007 44 Female 128 lb 1/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Death 45 Female 1/25/2008 Physician Canada
Primary
Concomitant
Tremor Other Serious 11/12/2007 44 Female 1/18/2008 United Kingdom
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 1/1/2007 42 Male 1/28/2008 Consumer Germany
Primary
Concomitant
Tremor Other Serious 11/12/2007 44 Female 1/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 11/21/2006 2/14/2008 Physician Canada
Primary
Concomitant
Dysarthria Other Serious Female 183 lb 3/11/2008 Canada
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 87 Male 3/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 2/18/2008 86 Female 3/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Proteinuria Other Serious 12/1/2007 Male 3/26/2008 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 3/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 87 Male 3/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 87 Male 3/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dysarthria Other Serious Female 183 lb 4/4/2008 Canada
Primary
Concomitant
Weight Fluctuation Other Serious 8/4/2001 31 Male 4/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/7/2008 Female 4/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Fluctuation Other Serious 8/4/2001 31 Male 5/5/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/27/2008 61 Male 5/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Shock Other Serious 3/27/2008 60 Male 5/16/2008 Other Health Professional France
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 1/1/2008 60 Male 5/16/2008 Consumer France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/2008 47 Female 5/27/2008 Other Health Professional France
Primary
Concomitant
Tachycardia Hospitalization 5/14/2008 Male 5/29/2008 Physician Germany
Primary
Secondary
Vision Blurred Hospitalization 4/24/2002 47 Female 6/9/2008 Physician United Kingdom
Primary
Concomitant
Drug Toxicity Other Serious 58 Male 6/9/2008 Physician Canada
Primary
Secondary
Gamma-glutamyltransferase Increased Other Serious 1/22/2008 72 Female 207 lb 6/23/2008 Physician France
Primary
Concomitant
Withdrawal Syndrome Hospitalization 4/24/2002 47 Female 7/2/2008 Physician United Kingdom
Primary
Concomitant
Narcotic Intoxication Death 8/18/2001 Female 84 lb 7/7/2008 Other Health Professional Canada
Primary
Concomitant
Overdose Hospitalization 52 Male 7/29/2008 Other Health Professional Canada
Primary
Secondary
Lower Respiratory Tract Infection Death 66 Male 8/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sinus Tachycardia Life Threatening 8/11/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 4/21/2008 22 Female 154 lb 8/14/2008 Physician Germany
Primary
Concomitant
Interacting
Malaise Other Serious 7/28/2008 67 Male 8/19/2008 Consumer United States
Primary
Concomitant
Interacting
Overdose Hospitalization 8/20/2008 Physician Canada
Primary
Secondary
Concomitant
Tremor Other Serious 5/31/2008 57 Female 8/22/2008 Physician Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2001 44 Female 8/28/2008 Physician United Kingdom
Primary
Concomitant
Malaise Other Serious 7/28/2008 67 Male 8/26/2008 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Death Death 8/22/2008 Male 174 lb 9/12/2008 Canada
Primary
Concomitant
Urinary Retention Hospitalization 15 Female 9/12/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 8/30/2008 Male 183 lb 9/19/2008 Canada
Primary
Secondary
Concomitant
Suicide Attempt Life Threatening 3/4/2004 69 Female 10/2/2008 China
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 8/30/2008 Male 183 lb 10/10/2008 Canada
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 8/30/2008 Male 183 lb 10/24/2008 Canada
Primary
Secondary
Concomitant
Neck Pain Disability 10/23/2008 Female 11/4/2008 Consumer Canada
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 1/1/2007 42 Male 11/6/2008 Consumer Germany
Primary
Concomitant
Sinus Tachycardia Hospitalization 52 Male 11/3/2008 Canada
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/16/2006 Female 132 lb 11/6/2008 Taiwan, Province Of China
Primary
Concomitant
Completed Suicide Life Threatening 4/6/2008 43 Male 11/5/2008 Germany
Primary
Secondary
Concomitant
Confusional State Other Serious 10/24/2008 75 Female 11/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 8/30/2008 Male 183 lb 11/14/2008 Canada
Primary
Secondary
Concomitant
Confusional State Other Serious 10/24/2008 75 Female 11/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Completed Suicide Death 7/1/2006 43 Male 172 lb 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neck Pain Disability 10/23/2008 Female 11/26/2008 Physician Canada
Primary
Concomitant
Tremor Other Serious 5/31/2008 57 Female 12/8/2008 Physician Canada
Primary
Secondary
Concomitant
Hypernatraemia Other Serious 1/1/2008 Male 12/17/2008 Pharmacist France
Primary
Concomitant
Sepsis Hospitalization 3/7/2008 Female 12/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 58 Male 1/6/2009 Physician Canada
Primary
Secondary
Grand Mal Convulsion Other Serious 37 Male 176 lb 1/23/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 1/5/2009 Female 3/3/2009 Physician Ireland
Primary
Concomitant
Motor Dysfunction Other Serious 1/29/2009 3/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Unevaluable Event Other Serious 2/1/2009 Male 181 lb 3/9/2009 Canada
Primary
Concomitant
Tinnitus Other Serious 2/1/2009 Male 181 lb 3/11/2009 Canada
Primary
Concomitant
Pulmonary Congestion Death 4/9/1998 Male 3/13/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Pulmonary Congestion Death 4/9/1998 Male 3/16/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Nightmare Hospitalization 3/31/2008 72 Female 3/13/2009 Germany
Primary
Secondary
Concomitant
Psychiatric Symptom Hospitalization 3/6/2008 72 Female 3/19/2009 Consumer Germany
Primary
Secondary
Concomitant
Overdose Other Serious 28 Female 3/24/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Sinus Tachycardia Other Serious 52 Male 4/7/2009
Primary
Secondary
Concomitant
Sepsis Hospitalization 11/15/2007 Female 4/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 3/25/2009 Male 4/9/2009 Physician New Zealand
Primary
Secondary
Concomitant
Tinnitus Other Serious 2/1/2009 Male 181 lb 4/22/2009 Canada
Primary
Concomitant
Hypertensive Crisis Life Threatening 1/19/2009 Male 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 69 Male 4/29/2009 Canada
Primary
Secondary
Concomitant
Renal Failure Hospitalization 69 Male 4/30/2009 Physician Canada
Primary
Secondary
Concomitant
Sedation Other Serious 1/1/2004 Male 5/26/2009 Other Health Professional Canada
Primary
Concomitant
Sedation Other Serious 1/1/2004 Male 6/4/2009 Other Health Professional Canada
Primary
Concomitant

Drug Data