Lorazepam combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
Vision Blurred 1/9/2006 83 Female 108 lb 1/13/2006 United States
Primary
Concomitant
Heart Rate Increased Hospitalization 11/1/2005 74 Male 2/3/2006 United States
Primary
Concomitant
Dehydration Hospitalization 9/16/2005 61 Female 2/13/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/26/2005 84 Male 245 lb 3/3/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Other Serious 1/13/2005 83 Male 134 lb 3/16/2006 Physician Canada
Primary
Concomitant
Renal Failure Other Serious 1/13/2005 83 Male 134 lb 3/17/2006 Physician Canada
Primary
Concomitant
Transfusion Reaction Death 8/13/2002 58 Female 155 lb 3/14/2006 Physician United States
Primary
Concomitant
Retroperitoneal Haemorrhage Other Serious 3/8/2006 Male 164 lb 4/24/2006 Physician Japan
Primary
Concomitant
Interacting
Urinary Tract Infection Other Serious 1/1/2004 Female 4/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/1/2006 Female 4/25/2006 Other Health Professional United States
Primary
Concomitant
Retching Hospitalization 4/6/2006 54 Male 140 lb 4/20/2006 Other Health Professional United States
Primary
Concomitant
Loss Of Consciousness Death 2/1/2005 50 Female 135 lb 5/1/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/20/2006 65 Male 5/8/2006 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Decreased Life Threatening 1/31/2006 29 Female 2/14/2006 United States
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Blood Parathyroid Hormone Increased 8/22/2005 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Blood Parathyroid Hormone Increased 8/22/2005 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Infected Skin Ulcer Hospitalization 4/1/2006 59 Male 109 lb 5/23/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/1/2005 62 Male 185 lb 6/12/2006 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2003 60 Male 185 lb 6/15/2006 Consumer United States
Primary
Concomitant
Palpitations Other Serious 2/16/2006 80 Female 158 lb 6/28/2006 Physician United States
Primary
Concomitant
Cerebral Infarction Death 6/29/2006 78 Female 7/13/2006 Physician Japan
Primary
Concomitant
Epistaxis 75 Male 152 lb 8/1/2006 Consumer United States
Primary
Concomitant
Therapy Non-responder Other Serious 1/1/2006 77 Female 8/14/2006 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/28/2003 56 Male 320 lb 8/21/2006 United States
Primary
Concomitant
Overdose Death 2/20/2003 Female 9/8/2006 Physician United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 72 Male 9/27/2006 Other Health Professional United States
Primary
Concomitant
Interacting
Pancytopenia Life Threatening 8/3/2005 54 Male 126 lb 10/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 72 Male 10/5/2006 Other Health Professional United States
Primary
Concomitant
Interacting
Thrombophlebitis Superficial Hospitalization 6/12/2006 39 Male 10/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 6/18/2006 87 Male 179 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Heart Rate Increased Hospitalization 11/1/2005 74 Male 7/18/2006 United States
Primary
Concomitant
Sinusitis Other Serious 72 Male 10/18/2006 Other Health Professional United States
Primary
Concomitant
Interacting
Gastrointestinal Haemorrhage Hospitalization 8/9/2006 80 Male 215 lb 8/15/2006 Pharmacist United States
Primary
Concomitant
Sepsis Required Intervention 9/19/2006 20 Female 273 lb 10/19/2006 Pharmacist United States
Primary
Concomitant
Respiratory Disorder Required Intervention 9/19/2006 20 Female 273 lb 10/19/2006 Pharmacist United States
Primary
Concomitant
Suicide Attempt Hospitalization 9/1/2006 62 Female 183 lb 10/24/2006 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Death 10/6/2006 Male 11/1/2006 Pharmacist United States
Primary
Concomitant
Surgery Other Serious 72 Female 11/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 1/1/1986 Male 212 lb 12/1/2006 Consumer Canada
Primary
Concomitant
Sedation Life Threatening 5/29/2006 82 Male 12/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Drug Ineffective 8/1/2006 82 Male 12/28/2006 Consumer United States
Primary
Concomitant
Pulmonary Oedema Death 11/22/2005 41 Male 170 lb 12/27/2006 United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 8/12/2006 Male 182 lb 10/11/2006 Pharmacist United States
Primary
Concomitant
Delusion Of Replacement Hospitalization 1/1/2006 77 Female 10/8/2006 Physician United States
Primary
Concomitant
Hypertension Other Serious 1/1/2005 81 Female 148 lb 11/16/2006 Other Health Professional United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 7/1/2006 81 Female 11/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 6/1/2006 78 Male 1/19/2007 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/24/2006 64 Male 1/11/2007 United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 6/22/2006 78 Male 1/16/2007 United Kingdom
Primary
Concomitant
Visual Acuity Reduced 6/22/2006 78 Male 1/23/2007 United Kingdom
Primary
Concomitant
Subdural Haematoma Life Threatening 75 Male 1/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Other Serious 9/6/2006 63 Female 134 lb 1/2/2007 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 10/23/2006 61 Male 124 lb 10/27/2006 Pharmacist United States
Primary
Concomitant
Visual Acuity Reduced 6/23/2006 78 Male 2/5/2007 United Kingdom
Primary
Concomitant
Subdural Haematoma Hospitalization 75 Male 2/6/2007 United States
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 75 Male 2/13/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Pain Other Serious 66 Male 201 lb 2/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Retroperitoneal Haematoma Other Serious 66 Male 201 lb 2/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Hospitalization 66 Male 2/20/2007 United Kingdom
Primary
Concomitant
Pulmonary Oedema Death 11/22/2005 41 Male 170 lb 2/20/2007 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/1/2006 66 Male 201 lb 3/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 66 Male 201 lb 2/23/2007 United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 66 Male 201 lb 2/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urticaria Other Serious 1/1/1999 69 Female 109 lb 3/1/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/12/2007 58 Female 3/20/2007 Pharmacist United States
Primary
Concomitant
Central Line Infection Hospitalization 3/2/2007 55 Female 3/23/2007 Consumer United States
Primary
Secondary
Concomitant
Pericardial Haemorrhage Required Intervention 67 Female 4/9/2007 Canada
Primary
Concomitant
Mental Status Changes Hospitalization 4/7/2007 92 Male 159 lb 4/20/2007 Pharmacist United States
Primary
Concomitant
Rash Other Serious Female 200 lb 4/27/2007 Physician United States
Primary
Concomitant
Interacting
Renal Failure Acute Other Serious 11/4/2006 59 Male 230 lb 11/8/2006 Physician United States
Primary
Concomitant
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
Palpitations Other Serious 83 Male 3/19/2007 Consumer United States
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 10/4/2006 59 Female 160 lb 1/14/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain 12/1/2006 60 Male 3/13/2007 Consumer United States
Primary
Concomitant
Headache 12/1/2006 78 Male 175 lb 4/12/2007 Consumer United States
Primary
Secondary
Concomitant
Insomnia 12/11/2006 80 Female 172 lb 4/12/2007 Consumer United States
Primary
Concomitant
Hepatorenal Failure Hospitalization 7/24/2006 63 Female 6/1/2007 Italy
Primary
Concomitant
Intracardiac Thrombus Life Threatening 67 Female 117 lb 6/26/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 6/20/2007 49 Female 6/28/2007 Pharmacist United States
Primary
Concomitant
Physical Assault Other Serious 1/1/2006 Male 167 lb 7/3/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/8/2007 94 Female 125 lb 4/25/2007 Pharmacist United States
Primary
Concomitant
Rash 5/11/2007 59 Female 7/6/2007 Consumer United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 78 Male 6/21/2007 Pharmacist United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 6/24/2007 46 Female 181 lb 7/6/2007 Consumer United States
Primary
Concomitant
Retroperitoneal Haematoma Other Serious 66 Male 7/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 66 Male 201 lb 7/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Hospitalization 5/1/2007 80 Female 8/1/2007 United States
Primary
Concomitant
Somnolence 89 Female 8/9/2007 Consumer United States
Primary
Concomitant
Pain Hospitalization 66 Male 201 lb 8/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Jugular Vein Thrombosis Other Serious 8/3/2007 68 Female 8/10/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/1/2006 66 Male 201 lb 8/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Hospitalization 66 Male 201 lb 8/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/5/2007 70 Female 140 lb 8/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 6/24/2007 46 Female 181 lb 8/29/2007 Physician United States
Primary
Concomitant
Movement Disorder Hospitalization 7/25/2007 Female 9/12/2007 Physician United Kingdom
Primary
Concomitant
Pancreatitis Acute Required Intervention 6/1/2007 80 Female 176 lb 9/14/2007 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 8/23/2007 83 Male 9/27/2007 Pharmacist United States
Primary
Secondary
Concomitant
Occult Blood Positive Other Serious 6/1/2007 Male 130 lb 10/5/2007 Physician Belgium
Primary
Concomitant
Weight Increased Other Serious 2/4/2006 Male 10/5/2007 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/5/2007 70 Female 140 lb 10/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 2/1/2007 47 Female 9/14/2007 Physician United States
Primary
Concomitant
Palpitations Other Serious 83 Male 9/12/2007 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 72 Male 10/18/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 5/19/2007 76 Female 132 lb 10/15/2007 Pharmacist United States
Primary
Concomitant
Red Man Syndrome Other Serious 5/26/2006 69 Female 10/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 75 Male 10/23/2007 Pharmacist United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 74 Female 10/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Hospitalization 8/31/2007 75 Female 168 lb 11/5/2007 Pharmacist United States
Primary
Concomitant
Tremor Other Serious Male 202 lb 11/21/2007 Physician United States
Primary
Concomitant
Intraventricular Haemorrhage Life Threatening 10/25/2007 74 Female 11/16/2007 Pharmacist United States
Primary
Concomitant
Physical Assault Other Serious 1/1/2006 Male 167 lb 12/28/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 8/24/2007 67 Female 1/9/2008 Other Health Professional United States
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 11/30/2007 49 Female 181 lb 1/16/2008 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 1/11/2008 Male 1/16/2008 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 1/1/2007 50 Female 2/20/2008 Consumer Canada
Primary
Concomitant
Skin Discolouration 56 Female 134 lb 2/25/2008 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 10/13/2007 58 Male 3/3/2008 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/8/2007 67 Female 135 lb 3/4/2008 Pharmacist United States
Primary
Secondary
Concomitant
Wheezing Hospitalization Female 231 lb 3/7/2008 Physician United States
Primary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 1/1/2002 27 Female 299 lb 3/24/2008 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/2/2008 85 Male 187 lb 4/17/2008 Pharmacist United States
Primary
Secondary
Concomitant
Urticaria Required Intervention 10/12/2007 73 Female 4/15/2008 Pharmacist United States
Primary
Concomitant
Death Death 1/29/2007 Male 176 lb 4/23/2008 Physician United States
Primary
Secondary
Concomitant
Sexual Dysfunction 5/29/2007 80 Male 5/30/2007 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 12/22/2007 Male 224 lb 4/25/2008 Physician United States
Primary
Concomitant
Cholecystitis Hospitalization 4/13/2008 Female 137 lb 4/28/2008 United States
Primary
Concomitant
Cholecystitis Hospitalization 4/13/2008 Female 137 lb 5/5/2008 United States
Primary
Concomitant
Knee Operation Other Serious 3/1/2008 86 Female 5/22/2008 Consumer United States
Primary
Concomitant
Myalgia Other Serious Female 140 lb 6/5/2008 United States
Primary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Other Serious 61 Female 6/4/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious Female 6/11/2008 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/28/2003 Male 320 lb 6/19/2008 Lawyer United States
Primary
Concomitant
Tremor Other Serious 61 Female 6/17/2008 Other Health Professional United States
Primary
Concomitant
Haemorrhage Intracranial Death 6/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ascites Hospitalization 5/30/2008 Male 7/7/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/24/2006 74 Male 7/21/2008 United Kingdom
Primary
Concomitant
Tongue Disorder Hospitalization 7/22/2008 64 Female 127 lb 7/23/2008 Consumer United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 6/20/2007 Male 117 lb 7/25/2008 Italy
Primary
Concomitant
Ascites Hospitalization 5/30/2008 Male 7/30/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 74 Male 7/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pain Other Serious 6/17/2008 Female 145 lb 8/1/2008 Consumer United States
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 66 Male 7/29/2008 United Kingdom
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 7/22/2008 64 Female 127 lb 8/5/2008 United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 4/1/2008 Female 275 lb 8/7/2008 Consumer United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Death 66 Male 8/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 6/1/2008 Female 145 lb 8/11/2008 Consumer United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 4/1/2008 Female 275 lb 8/14/2008 Consumer United States
Primary
Secondary
Concomitant
Ventricular Septal Defect Other Serious Female 8/12/2008 United Kingdom
Primary
Concomitant

Drug Data