Lorazepam combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Gamma-glutamyltransferase Increased Required Intervention 11/24/2005 89 Female 129 lb 2/1/2006 Germany
Primary
Concomitant
Hyperkalaemia Life Threatening 11/22/2005 65 Male 298 lb 11/28/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Tension Female 2/8/2006 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2003 38 Female 2/13/2006 Physician Germany
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 2/14/2006 47 Male 150 lb 2/22/2006 United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 1/1/2006 74 Female 165 lb 3/3/2006 Consumer United States
Primary
Concomitant
Hyperkalaemia Required Intervention 3/6/2006 79 Male 184 lb 3/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2006 47 Male 150 lb 3/10/2006 United States
Primary
Concomitant
Wheezing Other Serious 63 Male 3/16/2006 Pharmacist United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2006 47 Male 150 lb 3/24/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/4/2003 63 Female 154 lb 4/10/2006 Lawyer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2006 47 Male 150 lb 4/7/2006 Physician United States
Primary
Concomitant
Supraventricular Extrasystoles Hospitalization 7/31/2000 49 Male 4/24/2006 Lawyer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 11/27/2001 69 Female 121 lb 4/25/2006 Physician United States
Primary
Concomitant
Wheezing Other Serious 63 Male 4/25/2006 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Other Serious 3/22/2005 81 Female 4/27/2006 Canada
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 7/31/2000 49 Male 5/8/2006 Physician United States
Primary
Concomitant
Psoriasis Hospitalization 2/14/2006 Male 5/5/2006 Physician Belgium
Primary
Concomitant
Tooth Extraction Other Serious 68 Male 5/23/2006 United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 1/27/2006 74 Female 165 lb 5/30/2006 Consumer United States
Primary
Concomitant
Wheezing Other Serious 63 Male 6/6/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2005 Female 283 lb 6/19/2006 Consumer United States
Primary
Concomitant
Tooth Infection Other Serious 6/1/2006 59 Female 8/4/2006 Physician United States
Primary
Concomitant
Thinking Abnormal 5/1/2006 64 Male 200 lb 7/12/2006 Consumer United States
Primary
Concomitant
Tooth Extraction Other Serious 5/1/2006 68 Male 8/17/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 71 Female 155 lb 8/22/2006 United States
Primary
Concomitant
Therapy Non-responder Other Serious 1/1/2006 77 Female 8/14/2006 Physician United States
Primary
Concomitant
Myalgia Required Intervention 7/27/2006 47 Male 265 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 9/30/2005 66 Female 10/23/2006 Switzerland
Primary
Concomitant
Serotonin Syndrome Hospitalization 9/30/2005 66 Female 10/23/2006 Switzerland
Primary
Concomitant
Portal Vein Occlusion Hospitalization 10/9/2006 64 Female 11/3/2006 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Alopecia 2/1/2005 68 Male 11/13/2006 Consumer United States
Primary
Secondary
Dizziness Required Intervention 10/20/2006 83 Male 144 lb 11/1/2006 Other Health Professional United States
Primary
Concomitant
Neoplasm Hospitalization 10/9/2006 64 Female 11/14/2006 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Pancreatitis Chronic Other Serious 7/1/2006 45 Female 115 lb 11/20/2006 Physician Germany
Primary
Concomitant
Pseudocyst Other Serious 7/1/2006 45 Female 115 lb 11/20/2006 Physician Germany
Primary
Concomitant
Diverticulitis Other Serious 11/12/2006 80 Male 12/4/2006 Other Health Professional Japan
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 10/9/2006 64 Female 12/20/2006 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Pulmonary Oedema Death 11/22/2005 41 Male 170 lb 12/27/2006 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 10/17/2006 93 Female 1/2/2007 Italy
Primary
Secondary
Concomitant
Delusion Of Replacement Hospitalization 1/1/2006 77 Female 10/8/2006 Physician United States
Primary
Concomitant
Peripheral Ischaemia Hospitalization 93 Female 1/9/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Jaundice Hospitalization 10/9/2006 Female 1/16/2007 Taiwan, Province Of China
Primary
Concomitant
Delusion Of Replacement Hospitalization 1/1/2006 77 Female 10/8/2006 Physician United States
Primary
Concomitant
Localised Infection Other Serious 4/1/2006 57 Male 255 lb 1/30/2007 United States
Primary
Concomitant
Feeling Jittery 9/9/2006 76 Female 156 lb 10/16/2006 Consumer United States
Primary
Concomitant
Pulmonary Oedema Death 11/22/2005 41 Male 170 lb 2/20/2007 United States
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 1/27/2007 83 Female 3/7/2007 Other Health Professional France
Primary
Concomitant
Congestive Cardiomyopathy Other Serious 8/9/2004 46 Female 173 lb 11/27/2006 United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious Female 3/23/2007 Lawyer United States
Primary
Concomitant
Rash Erythematous Hospitalization 1/27/2007 83 Female 3/29/2007 Other Health Professional France
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 93 Female 3/27/2007 Italy
Primary
Secondary
Concomitant
Myalgia 11/8/2006 71 Female 116 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2002 Female 202 lb 4/4/2007 Physician United States
Primary
Secondary
Concomitant
Blood Creatine Increased Required Intervention 4/24/2006 39 Male 237 lb 1/3/2007 United States
Primary
Concomitant
Rash Other Serious Female 200 lb 4/27/2007 Physician United States
Primary
Concomitant
Interacting
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 5/1/2007 Physician United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 4/30/2007 63 Female 220 lb 5/16/2007 Consumer United States
Primary
Concomitant
Musculoskeletal Stiffness Life Threatening 4/23/2007 83 Female 5/15/2007 Finland
Primary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 5/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 1/22/2006 66 Female 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Intracardiac Thrombus Life Threatening 67 Female 117 lb 6/26/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 6/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 6/24/2007 46 Female 181 lb 7/6/2007 Consumer United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 4/6/2007 Female 128 lb 7/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Haemodynamic Instability Life Threatening 7/5/2007 Male 159 lb 7/23/2007 Physician Switzerland
Primary
Concomitant
Vision Blurred 3/23/2007 72 Female 133 lb 7/10/2007 Consumer United States
Primary
Concomitant
Hepatotoxicity Other Serious 38 Female 8/3/2007 Germany
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 6/24/2007 46 Female 181 lb 8/29/2007 Physician United States
Primary
Concomitant
Panic Attack Other Serious 8/1/2007 Female 200 lb 9/5/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious Female 9/1/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus 11/17/2000 35 Female 216 lb 9/18/2007 Other Health Professional United States
Primary
Concomitant
Pancreatitis Acute Required Intervention 6/1/2007 80 Female 176 lb 9/14/2007 Consumer United States
Primary
Concomitant
Completed Suicide Life Threatening 7/5/2007 Male 159 lb 10/2/2007 Physician Switzerland
Primary
Concomitant
Weight Decreased Death 1/1/2007 Female 160 lb 10/4/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 2/4/2006 Male 10/5/2007 United States
Primary
Secondary
Concomitant
Drug Administration Error 7/1/2007 65 Female 10/11/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Death 9/29/2007 63 Male 10/18/2007 Other Health Professional United States
Primary
Concomitant
Meningitis Death 11/10/2006 66 Female 11/20/2007 Physician Germany
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 73 Male 12/18/2007 Physician Switzerland
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/21/2007 76 Female 12/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/21/2007 76 Female 12/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 9/1/2007 62 Female 147 lb 1/18/2008 Physician United States
Primary
Concomitant
Vitreous Floaters Death 12/7/2007 53 Male 231 lb 2/4/2008 Physician United States
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 5/25/2007 Male 2/14/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Chronic Death 11/11/2007 Male 2/21/2008 Pharmacist United States
Primary
Concomitant
Swelling 11/1/2007 69 Male 234 lb 3/11/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 2/6/2008 76 Male 195 lb 3/7/2008 Other Health Professional United States
Primary
Concomitant
Quadriparesis Hospitalization 1/1/2008 47 Male 220 lb 3/5/2008 Consumer United States
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 1/1/2002 27 Female 299 lb 3/24/2008 Physician United States
Primary
Concomitant
Paralysis Required Intervention 1/1/2008 47 Male 220 lb 4/1/2008 United States
Primary
Concomitant
Unevaluable Event Required Intervention 1/1/2008 47 Male 220 lb 4/3/2008 United States
Primary
Concomitant
Waist Circumference Increased Other Serious 6/3/2006 Male 5/1/2008 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 Female 175 lb 5/6/2008 Pharmacist United States
Primary
Concomitant
Paraesthesia Hospitalization 5/7/2008 Female 245 lb 5/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Paralysis Required Intervention 1/1/2008 47 Male 220 lb 5/14/2008 United States
Primary
Concomitant
Paraesthesia Hospitalization 5/7/2008 Female 245 lb 6/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia Oral 5/3/2008 Female 278 lb 6/13/2008 United States
Primary
Concomitant
Hepatic Failure Hospitalization 8/9/2007 Male 185 lb 7/1/2008 United States
Primary
Concomitant
Pain Hospitalization 7/13/2007 77 Female 7/3/2008 Physician Belgium
Primary
Concomitant
Ascites Hospitalization 5/30/2008 Male 7/30/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 6/1/2008 Female 342 lb 7/30/2008 Consumer United States
Primary
Concomitant
Lung Disorder Hospitalization 4/1/2008 Female 342 lb 7/31/2008 Consumer United States
Primary
Concomitant
Waist Circumference Increased Other Serious 6/3/2006 Male 8/4/2008 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 6/30/2008 74 Female 192 lb 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Waist Circumference Increased Other Serious 6/3/2006 Male 8/26/2008 Lawyer United States
Primary
Concomitant
Ascites Hospitalization 5/30/2008 Male 8/26/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 2/1/2005 Female 267 lb 8/28/2008 Physician United States
Primary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 9/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Waist Circumference Increased Other Serious 6/3/2006 Male 9/5/2008 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 6/30/2008 74 Female 192 lb 9/4/2008 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 6/30/2008 74 Female 192 lb 9/15/2008 Physician United States
Primary
Secondary
Concomitant
Waist Circumference Increased Other Serious 6/3/2006 Male 9/19/2008 Lawyer United States
Primary
Concomitant
Tooth Extraction Other Serious 2/1/1998 Male 10/29/2008 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9/1/2008 Female 11/3/2008 Consumer United States
Primary
Concomitant
Waist Circumference Increased Other Serious 6/3/2006 Male 11/14/2008 Lawyer United States
Primary
Concomitant
Urosepsis Other Serious 9/1/2008 Female 11/13/2008 Physician United States
Primary
Concomitant
Ascites Hospitalization 5/30/2008 Male 12/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 12/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 1/1/2008 47 Male 220 lb 12/4/2008 United States
Primary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 12/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Ascites Hospitalization 5/30/2008 Male 12/31/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 80 Female 1/14/2009 Pharmacist Canada
Primary
Concomitant
Interacting
Psychomotor Hyperactivity Other Serious 11/30/2007 59 Female 229 lb 1/13/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/26/2008 Female 1/22/2009 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 2/1/1998 Male 2/19/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2007 71 Female 2/20/2009 Lawyer United States
Primary
Concomitant
Chest Pain Hospitalization Female 195 lb 3/3/2009 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization Female 195 lb 3/5/2009 Physician United States
Primary
Concomitant
Abdominal Neoplasm Hospitalization Male 230 lb 3/5/2009 Consumer United States
Primary
Concomitant
Tooth Extraction Other Serious 2/1/1998 Male 3/9/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 10/20/2008 67 Female 3/9/2009 Other Health Professional France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 6/22/2008 80 Female 3/12/2009 Pharmacist Canada
Primary
Concomitant
Interacting
Vomiting Other Serious 9/27/2008 74 Female 3/31/2009
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Death 1/1/1996 45 Male 4/2/2009 United States
Primary
Concomitant
Sepsis Death 1/1/2006 40 Male 4/3/2009 United States
Primary
Concomitant
Pulmonary Hypertension Death Female 195 lb 4/8/2009 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 2/1/1998 Male 4/10/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 7/29/2003 43 Male 249 lb 4/21/2009 United States
Primary
Concomitant
Pruritus Disability 10/15/2008 Female 108 lb 4/23/2009 Physician United States
Primary
Concomitant
Seborrhoeic Dermatitis Other Serious 12/1/2008 57 Male 119 lb 4/24/2009 Physician Germany
Primary
Secondary
Concomitant
Nausea Male 5/4/2009 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 4/26/2009 51 Male 271 lb 5/5/2009 Pharmacist United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 4/7/2009 36 Male 5/14/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 11/17/2000 35 Female 210 lb 5/15/2009 United States
Primary
Concomitant
Stress Other Serious 3/12/2004 44 Male 350 lb 5/20/2009 United States
Primary
Concomitant
Urosepsis Other Serious 5/1/1998 39 Male 275 lb 5/20/2009 United States
Primary
Concomitant
Tooth Extraction Other Serious 2/1/1998 Male 5/20/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 3/2/2009 72 Female 5/26/2009 Physician Switzerland
Primary
Secondary
Concomitant
Pneumonia Other Serious 2/14/2006 Male 150 lb 5/27/2009 Other Health Professional United States
Primary
Concomitant
Interacting

Drug Data