Lorazepam combined with Sodium Bicarbonate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 11/9/2005 64 Male 171 lb 1/5/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 12/2/2004 65 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 12/18/2004 38 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Weight Increased Other Serious 10/1/2005 59 Male 198 lb 1/24/2006 Pharmacist Spain
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 6/9/2006 48 Female 227 lb 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Anaemia 9/2/2005 Female 213 lb 8/9/2006 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/14/2007 Female 112 lb 2/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 5/10/2006 41 Male 8/31/2006 Pharmacist United States
Primary
Concomitant
Toothache 8/4/2006 50 Female 317 lb 9/20/2007 Consumer United States
Primary
Concomitant
Dyspnoea Life Threatening 6/8/2007 53 Female 169 lb 10/4/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/28/2007 14 Female 126 lb 11/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 126 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 8/24/2007 67 Female 1/9/2008 Other Health Professional United States
Primary
Concomitant
Poriomania Other Serious 4/20/2007 34 Female 1/14/2008 Other Health Professional Japan
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/12/2008 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/13/2008 Physician United States
Primary
Concomitant
Rash Erythematous Hospitalization 12/24/2007 64 Male 2/24/2008 United States
Primary
Secondary
Concomitant
Hypotension 12/1/2007 50 Male 315 lb 3/11/2008 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 12/15/2004 59 Male 3/7/2008 Physician Germany
Primary
Secondary
Tachycardia Other Serious 2/13/2008 Male 165 lb 3/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhage Other Serious 6/28/2004 64 Male 4/29/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 2/13/2008 Male 165 lb 4/29/2008 Consumer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11 Male 5/13/2008
Primary
Concomitant
Renal Failure Other Serious 1/1/2007 45 Male 5/19/2008 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2007 45 Male 6/3/2008 Physician United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2007 45 Male 7/31/2008 Physician United States
Primary
Concomitant
Troponin I Increased Hospitalization 1/30/2008 Female 213 lb 1/9/2009 Physician United States
Primary
Concomitant
Completed Suicide Other Serious 41 Female 1/23/2009 Physician United States
Primary
Secondary
Serotonin Syndrome Hospitalization 9 Male 68 lb 1/23/2009
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2007 71 Female 2/20/2009 Lawyer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 Female 213 lb 3/9/2009 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 7/9/2009 United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 8/4/2009 United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/23/2008 24 10/28/2009 Physician Korea, Republic Of
Primary
Concomitant
Renal Failure Acute Life Threatening 8/23/2008 24 Male 148 lb 11/9/2009 Physician Korea, Republic Of
Primary
Concomitant
Vomiting Other Serious 1/1/2005 71 Female 146 lb 12/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Schizophrenia, Catatonic Type Other Serious 2/1/2008 57 Male 12/16/2009 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 7/8/2008 34 Female 1/7/2010 Consumer United States
Primary
Secondary
Concomitant
Hepatotoxicity Death 9/21/2009 33 Female 1/21/2010 Pharmacist Spain
Primary
Concomitant
Visual Impairment Other Serious 11/27/2007 58 Female 123 lb 2/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 2/4/2010 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 2/18/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 10/15/2009 Female 175 lb 2/26/2010 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 3/10/2010 Female 130 lb 3/14/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2010 Female 130 lb 3/18/2010 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2010 65 Female 3/25/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/1/2008 34 Female 117 lb 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 71 Female 146 lb 4/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 69 Male 142 lb 4/26/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 5/3/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 5/7/2010 Other Health Professional United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 50 Male 5/10/2010
Primary
Secondary
Lung Neoplasm Malignant Other Serious 1/1/2008 73 Male 6/10/2010 Lawyer United States
Primary
Concomitant
Septic Shock Death 5/10/2006 41 Male 6/29/2010 Pharmacist United States
Primary
Concomitant
Respiratory Tract Inflammation Other Serious 4/1/2010 64 Male 6/28/2010 Physician United States
Primary
Concomitant
Somnolence Other Serious 6/1/2010 69 Female 100 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 69 Male 142 lb 7/2/2010 United States
Primary
Secondary
Concomitant
Respiratory Tract Inflammation Other Serious 4/1/2010 64 Male 7/7/2010 Physician United States
Primary
Concomitant
Hypotension Other Serious 1/3/2008 76 Male 7/7/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious Male 154 lb 7/12/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/2/2009 61 Male 154 lb 7/12/2010 Other Health Professional France
Primary
Secondary
Concomitant
Somnolence Other Serious 6/1/2010 69 Female 100 lb 7/12/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Tract Inflammation Other Serious 4/1/2010 64 Male 7/13/2010 Physician United States
Primary
Concomitant
Weight Increased 2/1/2008 44 Male 7/19/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 7/2/2009 61 Male 7/21/2010 Consumer France
Primary
Secondary
Concomitant
Splenomegaly Required Intervention 12/3/2006 9 Female 64 lb 7/23/2010 Physician United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2008 72 Male 8/5/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Life Threatening 8/23/2008 24 Male 148 lb 8/16/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pancreatic Mass Other Serious 2/1/2010 27 Male 216 lb 8/19/2010 Pharmacist Canada
Primary
Concomitant
Toxic Encephalopathy Hospitalization 7/19/2010 67 Female 146 lb 8/15/2010 Other Health Professional United States
Primary
Concomitant
Urosepsis Other Serious 1/1/2007 76 Male 8/26/2010 Other Health Professional United States
Primary
Concomitant
Tachycardia Other Serious 9/20/2007 50 Male 194 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/1/2010 61 Female 9/27/2010 Other Health Professional Netherlands
Primary
Concomitant
Urosepsis Other Serious 1/1/2007 76 Male 10/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tachypnoea Other Serious 9 Male 10/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tachypnoea Other Serious 9 Male 10/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/1/2008 12 Female 66 lb 10/28/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 69 Male 142 lb 11/11/2010 United States
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 10/1/2009 70 Female 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 11/22/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/1/2008 34 Female 117 lb 11/29/2010 Consumer United States
Primary
Secondary
Concomitant
Urosepsis Other Serious 1/1/2007 76 Male 12/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 11/1/2007 50 Male 262 lb 12/20/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Life Threatening 12/18/2010 55 Female 164 lb 12/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Headache Other Serious 9/1/2007 50 Male 194 lb 1/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 34 Female 1/13/2011 Physician United States
Primary
Secondary
Tumour Lysis Syndrome Other Serious 11/12/2006 61 Male 138 lb 1/14/2011 Physician Canada
Primary
Concomitant
Completed Suicide Death 34 Female 1/14/2011 Physician United States
Primary
Secondary
Multi-organ Failure Life Threatening 1/6/2011 79 Male 150 lb 1/18/2011 Physician Chile
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 12/15/2004 59 Male 1/20/2011 Physician Germany
Primary
Secondary
Platelet Count Decreased 38 Male 161 lb 2/1/2011 Pharmacist United States
Primary
Concomitant
Completed Suicide Death 34 Female 2/7/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 1/1/2009 34 Female 1/26/2011 Physician United States
Primary
Secondary
Completed Suicide Death 34 Female 3/4/2011 Other Health Professional United States
Primary
Secondary
Aortic Aneurysm Other Serious 1/1/2004 69 Male 142 lb 3/7/2011 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Death 1/1/2010 61 Female 3/11/2011 Physician Netherlands
Primary
Secondary
Concomitant
Anaemia Other Serious 1/1/2005 71 Female 146 lb 4/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Completed Suicide Death 34 Female 3/18/2011 Other Health Professional United States
Primary
Secondary
International Normalised Ratio Increased Hospitalization 3/6/2011 4/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/6/2004 62 Female 126 lb 4/8/2011 Lawyer United States
Primary
Concomitant
Anxiety Other Serious 2/6/2004 62 Female 126 lb 4/8/2011 Lawyer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 4/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 8/9/2004 74 Male 183 lb 4/15/2011 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2004 69 Male 142 lb 4/28/2011 Physician United States
Primary
Secondary
Concomitant
Chills Death 3/6/2011 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Walking Disability Other Serious 3/1/2007 55 Female 190 lb 5/4/2011 Other Health Professional United States
Primary
Concomitant
Stress Hospitalization 10/11/2005 75 Female 172 lb 5/12/2011 Consumer United States
Primary
Concomitant
Resuscitation Hospitalization 3/6/2011 6/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 4/7/2010 61 Female 6/10/2011 Physician Netherlands
Primary
Secondary
Concomitant
Fear Death 8/9/2004 74 Male 220 lb 6/20/2011 Consumer United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Death 6/13/2011 71 Male 211 lb 6/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 4/10/2011 27 Female 74 lb 6/29/2011 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/7/2011 60 Male 119 lb 7/21/2011 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/7/2011 60 Male 119 lb 8/11/2011 Pharmacist United States
Primary
Concomitant
Hyperkalaemia Hospitalization 7/9/2011 63 Female 102 lb 8/12/2011 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Death 6/13/2011 71 Male 211 lb 8/19/2011 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/13/2011 71 Male 211 lb 8/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Central Nervous System Lymphoma Other Serious 12/1/2010 67 Female 8/23/2011 United States
Primary
Concomitant
Dehydration Hospitalization 1/1/2007 81 Female 165 lb 9/13/2011 Lawyer United States
Primary
Concomitant
Pyrexia Hospitalization 10/25/2010 11 Male 66 lb 12/12/2011 Physician Japan
Primary
Concomitant
Suicidal Ideation Death 34 Female 12/14/2011 Other Health Professional United States
Primary
Secondary
Suicidal Ideation Death 34 Female 12/14/2011 Other Health Professional United States
Primary
Secondary
Dehydration Other Serious 4/1/2011 69 Female 137 lb 12/19/2011 United States
Primary
Concomitant
Dehydration Hospitalization 12/2/2011 12/23/2011 Consumer United States
Primary
Concomitant
Toxicity To Various Agents Death 34 Female 1/24/2012 Physician United States
Primary
Secondary
Dehydration Other Serious 4/1/2011 69 Female 137 lb 1/25/2012 United States
Primary
Concomitant
Arthralgia Other Serious 1/1/2009 52 Male 141 lb 2/8/2012 Lawyer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 8/18/2011 66 Male 239 lb 3/7/2012 Physician United States
Primary
Secondary
Concomitant
5Q Minus Syndrome Other Serious 1/10/2012 68 Male 173 lb 3/21/2012 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/25/2010 11 Male 66 lb 3/26/2012 Physician Japan
Primary
Concomitant
Sepsis Death 8/18/2011 66 Male 3/27/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Bronchitis Hospitalization 4/4/2011 55 Male 212 lb 4/5/2012 Physician Germany
Primary
Secondary
Concomitant
Completed Suicide Death 34 Female 4/10/2012 Other Health Professional United States
Primary
Secondary

Drug Data