Lorazepam combined with Nicotine

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Required Intervention 4/1/2002 39 Male 213 lb 12/30/2005 Physician United States
Primary
Concomitant
Pancreatitis Required Intervention 12/16/2005 46 Male 234 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Tachypnoea Hospitalization 11/15/2005 Male 2/21/2006 Pharmacist United States
Primary
Concomitant
Splenic Rupture Hospitalization 10/2/2000 Female 4/5/2006 Consumer United States
Primary
Secondary
Sinus Tachycardia Other Serious 10/1/2005 48 Male 4/7/2006 Physician United States
Primary
Concomitant
Sinus Bradycardia Life Threatening 1/25/2006 59 Male 250 lb 1/30/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/20/2006 65 Male 5/8/2006 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 4/6/2006 Female 5/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 4/6/2006 Female 5/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 8/1/2006 47 Male 166 lb 8/14/2006 United States
Primary
Secondary
Concomitant
Purple Glove Syndrome Other Serious 8/1/2006 47 Male 166 lb 8/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 4/6/2006 Female 9/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 1/24/2006 Male 176 lb 10/5/2006 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 1/24/2006 Male 176 lb 11/28/2006 Other Health Professional United States
Primary
Concomitant
Pruritus Other Serious 10/11/2006 55 Male 146 lb 10/11/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 7/1/2006 62 Male 139 lb 3/7/2007 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/1/2006 62 Male 139 lb 3/8/2007 United States
Primary
Secondary
Concomitant
Pyrexia Death 7/1/2006 62 Male 139 lb 3/8/2007 United States
Primary
Secondary
Concomitant
Rash Generalised Other Serious 2/7/2007 35 Female 101 lb 2/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Nightmare Other Serious 2/17/2007 52 Male 3/1/2007 Physician France
Primary
Concomitant
Pyrexia Death 7/1/2006 60 Male 139 lb 3/20/2007 United States
Primary
Secondary
Concomitant
Pyrexia Death 7/1/2006 60 Male 139 lb 4/5/2007 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 23 Male 6/5/2007 Pharmacist United States
Primary
Secondary
Concomitant
Peak Expiratory Flow Rate Decreased Other Serious 2/17/2007 53 Male 6/7/2007 Physician France
Primary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 6/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperprolactinaemia Other Serious 5/30/2007 19 Female 115 lb 6/29/2007 Pharmacist United States
Primary
Concomitant
Peak Expiratory Flow Rate Decreased Other Serious 2/17/2007 53 Male 172 lb 7/5/2007 Physician France
Primary
Concomitant
Urinary Tract Infection Hospitalization 10/13/2003 43 Female 271 lb 7/12/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2006 64 Female 7/13/2007 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 2/1/2006 64 Female 7/19/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Overdose Other Serious 7/21/2007 39 Male 144 lb 7/26/2007 Pharmacist United States
Primary
Concomitant
Dyspnoea Other Serious 8/7/2007 47 Male 8/16/2007 Consumer United States
Primary
Concomitant
Panic Disorder Other Serious 6/1/2007 42 Female 8/22/2007 Other Health Professional Finland
Primary
Secondary
Concomitant
Splenomegaly Death 3/12/2007 32 Male 165 lb 8/31/2007 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 23 Male 9/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 6/19/2007 64 Male 10/9/2007 Other Health Professional Switzerland
Primary
Concomitant
Mouth Haemorrhage Hospitalization 9/8/2007 66 Male 142 lb 10/17/2007 Pharmacist United States
Primary
Concomitant
Parkinsonism Death 9/16/2007 Female 150 lb 10/9/2007 Other Health Professional United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 3 Female 162 lb 11/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 Female 162 lb 11/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death 3/12/2007 32 Male 165 lb 10/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 31 Female 162 lb 12/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 31 Female 162 lb 12/14/2007 Consumer United States
Primary
Secondary
Concomitant
Pulse Pressure Decreased 1/20/2006 54 Male 160 lb 1/20/2006 Pharmacist United States
Primary
Secondary
Concomitant
Blood Sodium Decreased Hospitalization 45 Male 12/21/2007 Physician United Kingdom
Primary
Concomitant
Sepsis Death 10/30/2007 31 Female 162 lb 1/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 31 Female 162 lb 1/26/2008 Consumer United States
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 4/1/2001 Female 3/24/2008 Consumer United States
Primary
Concomitant
Tremor Hospitalization 23 Male 3/18/2008 Pharmacist United States
Primary
Concomitant
Suicidal Ideation Death 3/3/2007 20 Male 4/3/2008 Switzerland
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 Female 162 lb 4/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Panic Reaction Other Serious 12/16/2005 56 Male 4/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Streptococcal Infection Death 4/2/2008 47 Male 137 lb 5/9/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/19/2008 Female 147 lb 5/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Streptococcal Sepsis Death 4/2/2008 47 Male 137 lb 6/2/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/19/2008 Female 147 lb 6/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 7/8/2008 23 Male 227 lb 7/15/2008 Pharmacist United States
Primary
Concomitant
Lower Respiratory Tract Infection Death 66 Male 8/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/11/2007 Male 174 lb 8/25/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/11/2007 Male 174 lb 8/21/2008 Physician United States
Primary
Concomitant
Dyspnoea Other Serious Female 8/29/2008 Consumer United States
Primary
Concomitant
Death Death 8/22/2008 Male 174 lb 9/12/2008 Canada
Primary
Concomitant
Dyspnoea Other Serious Female 9/23/2008 Consumer United States
Primary
Concomitant
Overdose Death 8/1/2008 27 Male 220 lb 10/17/2008 Physician Switzerland
Primary
Concomitant
Rash Hospitalization 5/8/2008 49 Male 7/17/2008 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 80 Female 1/14/2009 Pharmacist Canada
Primary
Concomitant
Interacting
Tremor Other Serious 1/1/2004 Male 2/25/2009 Consumer
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/22/2008 80 Female 3/12/2009 Pharmacist Canada
Primary
Concomitant
Interacting
Suicidal Ideation Other Serious 10/1/1997 42 Male 236 lb 4/3/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2002 45 Male 230 lb 4/6/2009 United States
Primary
Concomitant
Nightmare Other Serious 11/1/2008 Female 243 lb 4/2/2009 Physician United States
Primary
Concomitant
Tremor Other Serious 1/1/2004 Male 4/9/2009 Consumer
Primary
Concomitant
Wheezing Hospitalization 7/16/2005 43 Female 154 lb 4/21/2009 Other Health Professional United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 4/7/2009 36 Male 5/14/2009 Physician United States
Primary
Concomitant
Urosepsis Other Serious 5/1/1998 39 Male 275 lb 5/20/2009 United States
Primary
Concomitant
Pyrexia Hospitalization 5/28/2009 54 166 lb 5/29/2009 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 47 Female 201 lb 7/30/2009 United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 10/1/2005 55 Male 229 lb 9/23/2009 United States
Primary
Concomitant
Urinary Tract Infection 5/25/2001 35 Female 100 lb 9/23/2009 United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 2/25/2002 25 Female 9/23/2009 United States
Primary
Concomitant
Sepsis Other Serious 4/11/2008 69 Male 10/28/2009 Lawyer United States
Primary
Concomitant
Schizophrenia Death 9/17/2009 Male 11/13/2009 Pharmacist United Kingdom
Primary
Concomitant
Schizophrenia Death 9/17/2009 Male 11/16/2009 Pharmacist United Kingdom
Primary
Concomitant
Metastases To Lymph Nodes Other Serious Female 132 lb 12/3/2009 Other Health Professional Canada
Primary
Concomitant
Sepsis Other Serious 4/11/2008 69 Male 2/1/2010 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Required Intervention 10/26/2008 Male 166 lb 11/18/2008 Other Health Professional United States
Primary
Concomitant
Overdose Other Serious 5/9/2009 Male 200 lb 3/2/2010 Consumer United States
Primary
Concomitant
Transitional Cell Carcinoma Other Serious 12/1/2007 60 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Pancreatitis Chronic Other Serious 12/1/2007 Male 220 lb 3/19/2010 Consumer United States
Primary
Concomitant
Laboratory Test Abnormal Other Serious 3/18/2010 46 Male 185 lb 3/19/2010 Pharmacist United States
Primary
Concomitant
Metastases To Lymph Nodes Other Serious Female 132 lb 3/30/2010 Other Health Professional Canada
Primary
Concomitant
Sensation Of Foreign Body Other Serious 3/1/2010 17 Male 4/13/2010 Consumer Canada
Primary
Concomitant
Urinary Tract Infection Hospitalization 10/13/2003 43 Female 270 lb 4/16/2010 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 9/17/2009 30 Female 126 lb 5/3/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/17/2009 30 Female 126 lb 5/7/2010 Physician United States
Primary
Secondary
Concomitant
Transitional Cell Carcinoma Other Serious 11/29/2007 60 Male 183 lb 5/24/2010 Other Health Professional United States
Primary
Concomitant
Tooth Infection Other Serious 3/4/1996 25 Female 5/27/2010 Pharmacist United States
Primary
Secondary
Concomitant
Viral Infection Life Threatening 10/11/2009 59 Female 190 lb 6/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Feeling Abnormal 11/20/2006 78 Female 7/8/2010 Other Health Professional United States
Primary
Concomitant
Hypoxia Hospitalization Female 8/25/2010 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity 2/26/2010 25 Female 3/16/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 4/11/2008 69 Male 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 11/1/2002 31 Female 98 lb 9/17/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2010 52 Female 148 lb 9/22/2010 Physician United States
Primary
Concomitant
Vaginitis Bacterial Other Serious 3/4/1996 25 Female 9/28/2010 Pharmacist United States
Primary
Secondary
Concomitant
Hypoxia Hospitalization Female 10/1/2010 Physician United States
Primary
Concomitant
Condition Aggravated Other Serious 45 Female 10/12/2010 Physician
Primary
Secondary
Concomitant
Mental Disorder Other Serious 45 Female 10/13/2010 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious 5/1/2010 52 Male 110 lb 10/14/2010 Physician United States
Primary
Concomitant
Mental Disorder Other Serious 45 Female 10/29/2010 Physician United States
Primary
Secondary
Mental Disorder Other Serious 45 Female 10/29/2010 Physician United States
Primary
Secondary
Narcotic Intoxication Death 3/7/2007 48 Female 160 lb 10/29/2010 Other Health Professional United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious Male 147 lb 10/27/2010 Physician United States
Primary
Concomitant
Mental Disorder Hospitalization 45 Female 11/3/2010 Physician United States
Primary
Secondary
Tumour Lysis Syndrome Other Serious 5/1/2010 52 Male 110 lb 11/4/2010 Physician United States
Primary
Secondary
Concomitant
Mental Disorder Other Serious 45 Female 11/24/2010 Physician United States
Primary
Secondary
Mental Disorder Hospitalization 45 Female 11/8/2010 United States
Primary
Secondary
Mental Disorder Hospitalization 45 Female 12/1/2010 Other Health Professional United States
Primary
Secondary
Cerebrovascular Accident Other Serious 1/28/2010 66 Male 11/19/2010 Physician United States
Primary
Secondary
Mental Status Changes Other Serious 6/1/2010 52 Male 153 lb 12/9/2010 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/1/2010 52 Male 110 lb 12/21/2010 Physician United States
Primary
Secondary
Concomitant
Drug Administered At Inappropriate Site Death 3/7/2007 48 Female 160 lb 1/6/2011 Lawyer United States
Primary
Concomitant
Glossitis Other Serious 68 Female 1/13/2011 Consumer United States
Primary
Concomitant
Radiculitis Lumbosacral Hospitalization 3/4/1996 25 Female 1/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Crohn's Disease 12/12/2010 29 Male 1/30/2011 Consumer United States
Primary
Concomitant
Completed Suicide Death 1/1/2009 55 Female 2/4/2011 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious Male 2/22/2011 Physician New Zealand
Primary
Concomitant
Drug Administered At Inappropriate Site Death 3/7/2007 48 Female 160 lb 3/17/2011 Lawyer United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 10/11/2009 59 Female 190 lb 3/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Off Label Use Hospitalization 7/1/2007 62 Male 220 lb 5/6/2011 Consumer United States
Primary
Concomitant
Pharyngitis Other Serious 3/4/1996 25 Female 6/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Life Threatening 9/23/2010 51 Male 181 lb 7/6/2011 Physician United States
Primary
Concomitant
Headache Other Serious 7/9/2011 55 Female 7/18/2011 Consumer Brazil
Primary
Concomitant
Dizziness Hospitalization 1/1/2010 61 Female 7/28/2011 Consumer United States
Primary
Concomitant
Diabetes Mellitus Other Serious 7/12/2002 47 Male 236 lb 8/1/2011 Lawyer United States
Primary
Concomitant
Large Intestine Perforation Death 7/1/2011 52 Female 119 lb 9/12/2011 Physician United States
Primary
Concomitant
Prinzmetal Angina Other Serious 49 Female 130 lb 9/21/2011 Pharmacist United States
Primary
Concomitant
Interacting
Somnolence Hospitalization 49 Female 130 lb 9/23/2011 United States
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 9/28/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Mitral Valve Incompetence Hospitalization 10/5/2011 United States
Primary
Concomitant
Interacting
Heart Rate Decreased Hospitalization 49 Female 130 lb 10/4/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Heart Rate Decreased Hospitalization 49 Female 130 lb 10/11/2011 United States
Primary
Concomitant
Interacting
Rhonchi Hospitalization 64 Female 10/3/2011 Other Health Professional Netherlands
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 59 Male 11/21/2011 Pharmacist United States
Primary
Concomitant
Cerebral Haemorrhage Death 50 Female 150 lb 11/22/2011 Other Health Professional United States
Primary
Concomitant
Prinzmetal Angina Hospitalization 49 Female 130 lb 12/1/2011 United States
Primary
Concomitant
Nicotine Dependence Other Serious 1/1/2006 48 Female 220 lb 12/8/2011 Lawyer United States
Primary
Concomitant
Incorrect Dose Administered Other Serious 65 Female 172 lb 1/10/2012 Consumer France
Primary
Secondary
Concomitant
Metastases To Skin Other Serious 12/1/2011 1/18/2012 Other Health Professional United States
Primary
Concomitant
Blood Sodium Decreased Hospitalization 59 Male 1/24/2012 Pharmacist United States
Primary
Concomitant