Lorazepam combined with Metoprolol Succinate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Gamma-glutamyltransferase Increased Hospitalization 4/19/2005 63 Male 1/30/2006 Germany
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 4/19/2005 63 Male 2/1/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Death Death 12/1/2005 50 Male 2/6/2006 United States
Primary
Concomitant
Pain In Jaw Other Serious 12/1/2005 37 Female 160 lb 2/20/2006 Consumer United States
Primary
Secondary
Concomitant
Pruritus Generalised Other Serious 12/1/2005 37 Female 160 lb 3/8/2006 Consumer United States
Primary
Secondary
Concomitant
Contusion Hospitalization 3/17/2004 53 Female 190 lb 12/27/2005 Consumer United States
Primary
Concomitant
Pruritus Generalised Other Serious 12/1/2005 37 Female 160 lb 4/5/2006 Consumer United States
Primary
Secondary
Concomitant
Urticaria Other Serious 2/23/2006 55 Male 228 lb 4/7/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Viral Pharyngitis Hospitalization 1/1/2001 50 Female 320 lb 4/10/2006 Physician United States
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 5/5/2006 United States
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 47 Female 5/1/2006 Physician United States
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 47 Female 5/3/2006 United States
Primary
Secondary
Telangiectasia Hospitalization 1/5/2005 80 Male 5/31/2006 Physician France
Primary
Secondary
Concomitant
Rash Other Serious 6/6/2006 78 Male 190 lb 6/6/2006 Pharmacist United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/19/2006 62 Male 180 lb 6/21/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/13/2006 56 Female 180 lb 5/11/2006 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/1/2006 47 Female 9/18/2006 Pharmacist United States
Primary
Secondary
Lipase Increased Other Serious 4/1/2006 68 Female 10/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Anterior Chamber Inflammation Female 8/23/2006 Other Health Professional United States
Primary
Concomitant
Sudden Death Death 11/25/2005 69 Female 11/10/2006 Physician Germany
Primary
Secondary
Concomitant
Quadriplegia Other Serious 10/8/2006 59 Male 236 lb 11/10/2006 Pharmacist United States
Primary
Concomitant
Stress Other Serious 1/1/2006 79 Female 78 lb 11/16/2006 Physician United States
Primary
Secondary
Concomitant
Stomach Discomfort Death 88 Female 176 lb 12/8/2006 Physician Canada
Primary
Concomitant
Anaphylactic Reaction Other Serious 12/2/2006 Female 140 lb 12/11/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 10/3/2006 46 Female 185 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/6/2006 Female 88 lb 11/16/2006 Other Health Professional United States
Primary
Concomitant
Cardiomegaly Other Serious 4/24/2006 Female 160 lb 12/14/2006 Consumer Canada
Primary
Concomitant
Suspiciousness Hospitalization 7/29/2006 42 Female 12/8/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 12/21/2006 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 10/1/2006 Female 200 lb 12/29/2006 Physician United States
Primary
Concomitant
Short-bowel Syndrome Hospitalization 11/24/2006 72 Female 12/29/2006 Physician United States
Primary
Secondary
Concomitant
Lipase Increased Other Serious 4/1/2006 68 Female 1/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Glucose Increased Life Threatening 7/6/2006 Male 187 lb 7/12/2006 Pharmacist United States
Primary
Concomitant
Rectal Haemorrhage Required Intervention 8/15/2006 Female 160 lb 8/23/2006 Pharmacist United States
Primary
Concomitant
Occult Blood Positive Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Short-bowel Syndrome Hospitalization 11/24/2006 72 Female 1/10/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 200 lb 1/18/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 1/23/2007 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 10/23/2006 61 Male 124 lb 10/27/2006 Pharmacist United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 1/1/2007 68 Female 2/16/2007 Physician United Kingdom
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/29/2007 72 Female 375 lb 2/7/2007 Pharmacist United States
Primary
Concomitant
Sinus Arrhythmia Hospitalization 42 Male 2/23/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/30/2006 51 Female 3/6/2007 Physician Germany
Primary
Concomitant
Respiratory Distress Required Intervention 12/31/2006 49 Male 229 lb 3/6/2007 Pharmacist United States
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 200 lb 3/10/2007 United States
Primary
Secondary
Concomitant
Paranoia Disability 12/12/2006 42 Male 132 lb 3/13/2007 Physician Switzerland
Primary
Concomitant
Interacting
Intraventricular Haemorrhage Hospitalization 7/29/2006 Male 231 lb 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2003 46 Male 145 lb 3/22/2007 Physician United States
Primary
Concomitant
Pancytopenia Death 3/10/2007 37 Female 165 lb 3/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 4/2/2007 Physician United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 2/23/2007 79 Female 189 lb 3/27/2007 Pharmacist United States
Primary
Concomitant
Renal Impairment Life Threatening 10/13/2006 Female 121 lb 4/3/2007 Netherlands
Primary
Concomitant
Restlessness Hospitalization 11/8/2006 73 Male 123 lb 11/29/2006 Pharmacist United States
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 3/29/2007 73 Male 176 lb 4/9/2007 Physician United States
Primary
Secondary
Concomitant
Sinus Bradycardia Life Threatening 3/16/2007 72 Male 201 lb 4/7/2007 Switzerland
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 7/29/2006 42 Female 4/6/2007 Other Health Professional United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 4/16/2007 Female 4/20/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 3/29/2007 73 Male 176 lb 4/13/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Hospitalization 3/29/2007 73 Male 176 lb 4/25/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/30/2006 51 Female 5/7/2007 Physician Germany
Primary
Concomitant
Speech Disorder Other Serious 2/7/2003 83 Male 134 lb 5/14/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 5/16/2007 Physician United States
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Life Threatening 4/23/2007 83 Female 5/15/2007 Finland
Primary
Concomitant
Gastrointestinal Stromal Tumour Other Serious 6/16/2006 Male 158 lb 6/1/2007 Physician United States
Primary
Concomitant
Disease Progression Other Serious Female 117 lb 6/4/2007 Consumer Canada
Primary
Concomitant
Gait Disturbance Hospitalization 9/19/2006 52 Female 6/6/2007 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Disease Progression Other Serious Female 117 lb 6/22/2007 Consumer Canada
Primary
Concomitant
Speech Disorder Other Serious 2/7/2003 83 Male 134 lb 7/3/2007 Physician United States
Primary
Secondary
Concomitant
Physical Assault Other Serious 1/1/2006 Male 167 lb 7/3/2007 Consumer United States
Primary
Secondary
Concomitant
Speech Disorder Other Serious 2/7/2003 83 Male 134 lb 7/11/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3/29/2007 73 Male 176 lb 7/6/2007 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/26/2000 29 Female 155 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Overdose 6/28/2007 55 Female 7/16/2007 Physician Netherlands
Primary
Concomitant
Rash Required Intervention 7/9/2007 47 Female 188 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Middle Insomnia 5/1/2007 84 Male 160 lb 7/10/2007 Consumer United States
Primary
Concomitant
Gastrointestinal Stromal Tumour Other Serious 6/1/2006 Male 158 lb 8/14/2007 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 10/1/2000 Male 8/17/2007 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/5/2007 70 Female 140 lb 8/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Required Intervention 6/1/2007 48 Female 6/8/2007 United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 7/29/2007 69 Male 162 lb 8/16/2007 Other Health Professional United States
Primary
Concomitant
Nervous System Disorder Other Serious 6/10/2007 Male 201 lb 9/7/2007 Physician United States
Primary
Secondary
Concomitant
Retinal Vein Thrombosis Hospitalization 8/8/2007 72 Female 9/10/2007 Physician Germany
Primary
Concomitant
White Blood Cell Disorder Hospitalization 5/1/2007 62 Male 9/10/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 10/1/2000 Male 10/2/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 10/1/2000 Male 10/25/2007 Consumer United States
Primary
Concomitant
Heart Rate Increased 1/1/2006 Female 130 lb 12/14/2007 Consumer United States
Primary
Concomitant
Transplant Failure Hospitalization 12/13/2007 53 Male 225 lb 12/13/2007 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Hospitalization 1/4/2008 Female 1/30/2008 Other Health Professional Germany
Primary
Secondary
Oropharyngeal Candidiasis Hospitalization 2/3/2008 55 Male 221 lb 2/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/1/2000 Male 2/8/2008 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 2/5/2008 55 Male 218 lb 2/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 12/31/2007 Female 174 lb 2/28/2008 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/27/2004 76 Female 2/29/2008 Physician Germany
Primary
Secondary
Concomitant
Vomiting 1/30/2008 66 Female 170 lb 3/11/2008 Physician United States
Primary
Concomitant
Swollen Tongue Death 11/4/2004 Female 3/14/2008 Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 12/15/2004 59 Male 3/7/2008 Physician Germany
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 12/15/2004 Male 3/24/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Swollen Tongue Death 11/4/2004 Female 4/18/2008 Germany
Primary
Secondary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 4/29/2008 Physician Germany
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious Female 5/8/2008 Denmark
Primary
Secondary
Somnolence Hospitalization 2/16/2008 71 Female 165 lb 6/12/2008 United States
Primary
Concomitant
Swollen Tongue Life Threatening 6/8/2008 81 Male 222 lb 6/26/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 7/18/2008 67 Male 187 lb 7/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 2/16/2008 71 Female 165 lb 7/14/2008 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 38 Male 8/7/2008
Primary
Secondary
Concomitant
Mobility Decreased Hospitalization 2/1/2008 Female 208 lb 8/8/2008 Consumer United States
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/19/2008 Female 135 lb 8/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 4/2/2008 Female 200 lb 8/8/2008 Consumer United States
Primary
Secondary
Concomitant
Hypertension 12/19/2007 Male 160 lb 8/27/2008 Consumer United States
Primary
Concomitant
Skin Laceration Other Serious Female 11/17/2008 Physician Belgium
Primary
Secondary
Concomitant
Osteoporosis 6/1/2008 63 Female 200 lb 9/2/2008 Consumer United States
Primary
Concomitant
Pyrexia Life Threatening 10/26/2008 34 Female 11/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Ulceration 8/1/2008 Female 11/26/2008 United States
Primary
Concomitant
Urine Colour Abnormal 11/2/2007 Female 185 lb 12/4/2008 Physician United States
Primary
Concomitant
Wheezing 9/5/2008 Female 214 lb 12/12/2008 United States
Primary
Concomitant
Weight Increased Other Serious Male 12/29/2008 Other Health Professional Ireland
Primary
Concomitant
Blood Pressure Increased Male 1/12/2009 Pharmacist United States
Primary
Concomitant
Toxic Encephalopathy Hospitalization 9/14/2008 61 Female 1/8/2009 Other Health Professional Switzerland
Primary
Concomitant
Vomiting Other Serious 2/9/2008 Male 1/19/2009 Lawyer United States
Primary
Concomitant
Completed Suicide Death 69 Male 1/15/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 51 Female 1/19/2009 Physician United States
Primary
Secondary
Wheezing Other Serious 8/1/2007 55 Male 220 lb 1/27/2009 Consumer United States
Primary
Secondary
Concomitant
Poisoning Deliberate Death 69 Male 1/16/2009 Physician United States
Primary
Secondary
Vomiting Other Serious 2/9/2008 82 Male 2/19/2009 Lawyer United States
Primary
Concomitant
Tachycardia Death 1/24/2009 Male 157 lb 3/5/2009 Physician United States
Primary
Secondary
Concomitant
Parkinsonism 1/1/2008 60 Female 3/13/2009 Physician Germany
Primary
Concomitant
Neutropenia Hospitalization 3/1/2007 87 Female 192 lb 3/17/2009 Other Health Professional Austria
Primary
Secondary
Concomitant
Wound Hospitalization 5/16/2008 55 Female 112 lb 3/16/2009 Physician United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Life Threatening 10/26/2008 34 Female 3/13/2009 Physician United States
Primary
Secondary
Concomitant
Disease Progression Death 3/13/2009 Male 206 lb 4/2/2009 United States
Primary
Concomitant
Palpitations 69 Female 220 lb 4/21/2009 Consumer United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Life Threatening 10/26/2008 34 Female 4/13/2009 Physician United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 2/1/2009 Male 181 lb 4/22/2009 Canada
Primary
Concomitant
Somnolence Hospitalization 4/9/2009 50 Female 245 lb 4/27/2009 Pharmacist United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 3/18/2009 77 Male 137 lb 3/19/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2008 44 Male 192 lb 5/7/2009 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 5/1/2009 Male 6/1/2009 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2009 66 Male 6/3/2009 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 2/1/2008 71 Female 113 lb 6/4/2009 Consumer United States
Primary
Concomitant
Middle Ear Effusion Required Intervention 5/18/2009 Female 107 lb 6/3/2009 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 4/23/2009 Male 6/8/2009 Physician United States
Primary
Concomitant
Ischaemia Hospitalization 2/20/2007 Male 219 lb 6/10/2009 Ireland
Primary
Concomitant
Peritoneal Dialysis Hospitalization Male 152 lb 6/5/2009 Other Health Professional United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/29/2009 Male 160 lb 6/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/26/2000 29 Female 186 lb 6/17/2009 United States
Primary
Concomitant
Myelitis Hospitalization 1/1/2009 61 Female 141 lb 6/17/2009 Pharmacist United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 5/11/2009 55 Male 207 lb 6/22/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 10/14/2004 Male 188 lb 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Ischaemia Hospitalization 2/20/2007 Male 219 lb 6/24/2009 Ireland
Primary
Concomitant

Drug Data